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Search results 1 to 100 out of 405 for Men1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Chandrasekharappa SC
Year: 2003
Journal: J Intern Med
Title: Functional studies of the MEN1 gene.
Volume: 253
Issue: 6
Pages: 606-15
Publication
First Author: Khodaei S
Year: 1999
Journal: Biochem Biophys Res Commun
Title: Characterization of the MEN1 ortholog in zebrafish.
Volume: 264
Issue: 2
Pages: 404-8
Publication
First Author: Bertolino P
Year: 2003
Journal: Mol Endocrinol
Title: Heterozygous Men1 mutant mice develop a range of endocrine tumors mimicking multiple endocrine neoplasia type 1.
Volume: 17
Issue: 9
Pages: 1880-92
Publication
First Author: Gurung B
Year: 2013
Journal: Cancer Res
Title: Menin epigenetically represses Hedgehog signaling in MEN1 tumor syndrome.
Volume: 73
Issue: 8
Pages: 2650-8
Publication
First Author: Suphapeetiporn K
Year: 2002
Journal: Genes Chromosomes Cancer
Title: MEN1 tumor-suppressor protein localizes to telomeres during meiosis.
Volume: 35
Issue: 1
Pages: 81-5
Publication
First Author: Lu J
Year: 2010
Journal: Gastroenterology
Title: Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development.
Volume: 138
Issue: 5
Pages: 1954-65
Publication
First Author: Matoso A
Year: 2008
Journal: Carcinogenesis
Title: Cell lineage-specific interactions between Men1 and Rb in neuroendocrine neoplasia.
Volume: 29
Issue: 3
Pages: 620-8
Publication
First Author: Lejonklou MH
Year: 2012
Journal: Endocrinology
Title: Accelerated proliferation and differential global gene expression in pancreatic islets of five-week-old heterozygous Men1 mice: Men1 is a haploinsufficient suppressor.
Volume: 153
Issue: 6
Pages: 2588-98
Publication
First Author: Qiu H
Year: 2020
Journal: Nat Commun
Title: MEN1 deficiency leads to neuroendocrine differentiation of lung cancer and disrupts the DNA damage response.
Volume: 11
Issue: 1
Pages: 1009
Publication
First Author: Stewart C
Year: 1998
Journal: Oncogene
Title: Characterization of the mouse Men1 gene and its expression during development.
Volume: 17
Issue: 19
Pages: 2485-93
Publication
First Author: Li F
Year: 2015
Journal: Endocrinology
Title: Conditional deletion of Men1 in the pancreatic β-cell leads to glucagon-expressing tumor development.
Volume: 156
Issue: 1
Pages: 48-57
Publication
First Author: Libutti SK
Year: 2003
Journal: Cancer Res
Title: Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism.
Volume: 63
Issue: 22
Pages: 8022-8
Publication
First Author: Gillam MP
Year: 2015
Journal: Oncogene
Title: MEN1 tumorigenesis in the pituitary and pancreatic islet requires Cdk4 but not Cdk2.
Volume: 34
Issue: 7
Pages: 932-8
Publication
First Author: Lu J
Year: 2012
Journal: Oncogene
Title: Reexpression of oncoprotein MafB in proliferative β-cells and Men1 insulinomas in mouse.
Volume: 31
Issue: 31
Pages: 3647-54
Publication
First Author: Karges W
Year: 1999
Journal: Biochim Biophys Acta
Title: Primary structure, gene expression and chromosomal mapping of rodent homologs of the MEN1 tumor suppressor gene.
Volume: 1446
Issue: 3
Pages: 286-94
Publication
First Author: Guru SC
Year: 1999
Journal: Mamm Genome
Title: Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene.
Volume: 10
Issue: 6
Pages: 592-6
Publication
First Author: Schnepp RW
Year: 2006
Journal: Cancer Res
Title: Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells.
Volume: 66
Issue: 11
Pages: 5707-15
Publication
First Author: Walls GV
Year: 2012
Journal: Cancer Res
Title: MEN1 gene replacement therapy reduces proliferation rates in a mouse model of pituitary adenomas.
Volume: 72
Issue: 19
Pages: 5060-8
Publication
First Author: Monazzam A
Year: 2018
Journal: Sci Rep
Title: Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [68Ga]Ga-DO3A-VS-Cys40-Exendin-4 /PET.
Volume: 8
Issue: 1
Pages: 748
Publication
First Author: Chu X
Year: 2013
Journal: Am J Pathol
Title: Multiple microvascular alterations in pancreatic islets and neuroendocrine tumors of a Men1 mouse model.
Volume: 182
Issue: 6
Pages: 2355-67
Publication
First Author: Fontanière S
Year: 2006
Journal: Fam Cancer
Title: Analysis of p27(Kip1) expression in insulinomas developed in pancreatic beta-cell specific Men1 mutant mice.
Volume: 5
Issue: 1
Pages: 49-54
Publication
First Author: Forsberg L
Year: 2001
Journal: Int J Mol Med
Title: Differential expression of multiple alternative spliceforms of the Men1 tumor suppressor gene in mouse.
Volume: 8
Issue: 6
Pages: 681-9
Publication
First Author: Pei XH
Year: 2007
Journal: Cancer Res
Title: p18Ink4c collaborates with Men1 to constrain lung stem cell expansion and suppress non-small-cell lung cancers.
Volume: 67
Issue: 7
Pages: 3162-70
Publication
First Author: Bai F
Year: 2007
Journal: Mol Cell Biol
Title: p18Ink4c, but not p27Kip1, collaborates with Men1 to suppress neuroendocrine organ tumors.
Volume: 27
Issue: 4
Pages: 1495-504
Publication
First Author: Yang Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Reversal of preexisting hyperglycemia in diabetic mice by acute deletion of the Men1 gene.
Volume: 107
Issue: 47
Pages: 20358-63
Publication
First Author: Loffler KA
Year: 2007
Journal: Oncogene
Title: Lack of augmentation of tumor spectrum or severity in dual heterozygous Men1 and Rb1 knockout mice.
Volume: 26
Issue: 27
Pages: 4009-17
Publication
First Author: Wasylishen AR
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress.
Volume: 117
Issue: 12
Pages: 6622-6629
Publication
First Author: Teinturier R
Year: 2021
Journal: Oncogene
Title: Men1 disruption in Nkx3.1-deficient mice results in ARlow/CD44+ microinvasive carcinoma development with the dysregulated AR pathway.
Volume: 40
Issue: 6
Pages: 1118-1127
Publication
First Author: Bonnavion R
Year: 2017
Journal: J Pathol
Title: Foxa2, a novel protein partner of the tumour suppressor menin, is deregulated in mouse and human MEN1 glucagonomas.
Volume: 242
Issue: 1
Pages: 90-101
Publication
First Author: Lemos MC
Year: 2009
Journal: J Endocrinol
Title: Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: relevance to genetic modifiers.
Volume: 203
Issue: 1
Pages: 133-42
Publication
First Author: Biondi C
Year: 2002
Journal: Genesis
Title: Targeting and conditional inactivation of the murine Men1 locus using the Cre recombinase: loxP system.
Volume: 32
Issue: 2
Pages: 150-1
Publication
First Author: Biondi CA
Year: 2004
Journal: Mol Cell Biol
Title: Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues.
Volume: 24
Issue: 8
Pages: 3125-31
Publication
First Author: Mould AW
Year: 2009
Journal: Int J Cancer
Title: Global expression profiling of sex cord stromal tumors from Men1 heterozygous mice identifies altered TGF-beta signaling, decreased Gata6 and increased Csf1r expression.
Volume: 124
Issue: 5
Pages: 1122-32
Publication
First Author: Fontanière S
Year: 2006
Journal: Endocr Relat Cancer
Title: Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.
Volume: 13
Issue: 4
Pages: 1223-36
Publication
First Author: Walls GV
Year: 2016
Journal: Endocrinology
Title: Pasireotide Therapy of Multiple Endocrine Neoplasia Type 1-Associated Neuroendocrine Tumors in Female Mice Deleted for an Men1 Allele Improves Survival and Reduces Tumor Progression.
Volume: 157
Issue: 5
Pages: 1789-98
Publication
First Author: Hussein N
Year: 2008
Journal: Endocr Relat Cancer
Title: Deregulation of anti-Mullerian hormone/BMP and transforming growth factor-beta pathways in Leydig cell lesions developed in male heterozygous multiple endocrine neoplasia type 1 mutant mice.
Volume: 15
Issue: 1
Pages: 217-27
Publication
First Author: Hussein N
Year: 2007
Journal: Eur J Cancer
Title: Reconstituted expression of menin in Men1-deficient mouse Leydig tumour cells induces cell cycle arrest and apoptosis.
Volume: 43
Issue: 2
Pages: 402-14
Publication
First Author: Bertolino P
Year: 2003
Journal: Mech Dev
Title: Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs.
Volume: 120
Issue: 5
Pages: 549-60
Publication
First Author: Bertolino P
Year: 2003
Journal: Cancer Res
Title: Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice.
Volume: 63
Issue: 16
Pages: 4836-41
Publication
First Author: Căpraru OM
Year: 2016
Journal: Rom J Morphol Embryol
Title: Histopathological changes induced by selective inactivation of menin on the thyroid gland in RET÷PTC3 and E7 transgenic mice. A study of 77 cases.
Volume: 57
Issue: 1
Pages: 91-8
Publication
First Author: Gherardi S
Year: 2017
Journal: Biochim Biophys Acta
Title: Menin regulates Inhbb expression through an Akt/Ezh2-mediated H3K27 histone modification.
Volume: 1860
Issue: 4
Pages: 427-437
Publication
First Author: Fontanière S
Year: 2008
Journal: J Endocrinol
Title: Tumour suppressor menin is essential for development of the pancreatic endocrine cells.
Volume: 199
Issue: 2
Pages: 287-98
Publication
First Author: Balogh K
Year: 2010
Journal: Mol Cell Endocrinol
Title: Menin dynamics and functional insight: take your partners.
Volume: 326
Issue: 1-2
Pages: 80-4
Publication
First Author: Cheng P
Year: 2015
Journal: FEBS Lett
Title: Tumor suppressor Menin acts as a corepressor of LXRα to inhibit hepatic lipogenesis.
Volume: 589
Issue: 20 Pt B
Pages: 3079-84
Publication
First Author: Lemmens IH
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Menin interacts directly with the homeobox-containing protein Pem.
Volume: 286
Issue: 2
Pages: 426-31
Publication
First Author: Guo SS
Year: 2001
Journal: Mol Endocrinol
Title: Molecular and genetic mechanisms of tumorigenesis in multiple endocrine neoplasia type-1.
Volume: 15
Issue: 10
Pages: 1653-64
Publication
First Author: Agarwal SK
Year: 2005
Journal: Horm Metab Res
Title: Menin molecular interactions: insights into normal functions and tumorigenesis.
Volume: 37
Issue: 6
Pages: 369-74
Publication
First Author: Liu P
Year: 2017
Journal: Cell Death Differ
Title: Loss of menin in osteoblast lineage affects osteocyte-osteoclast crosstalk causing osteoporosis.
Volume: 24
Issue: 4
Pages: 672-682
Publication
First Author: Leng L
Year: 2018
Journal: Neuron
Title: Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation.
Volume: 100
Issue: 3
Pages: 551-563.e7
Publication
First Author: Zhuang K
Year: 2018
Journal: Cell Rep
Title: Neuron-Specific Menin Deletion Leads to Synaptic Dysfunction and Cognitive Impairment by Modulating p35 Expression.
Volume: 24
Issue: 3
Pages: 701-712
Publication
First Author: Vijayaraghavan J
Year: 2014
Journal: Am J Physiol Endocrinol Metab
Title: miR-24 regulates menin in the endocrine pancreas.
Volume: 307
Issue: 1
Pages: E84-92
Publication
First Author: Milne TA
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
Volume: 102
Issue: 3
Pages: 749-54
Publication
First Author: Cheng P
Year: 2011
Journal: FEBS Lett
Title: Menin prevents liver steatosis through co-activation of peroxisome proliferator-activated receptor alpha.
Volume: 585
Issue: 21
Pages: 3403-8
Publication
First Author: Feng Z
Year: 2017
Journal: Cancer Res
Title: Menin and Daxx Interact to Suppress Neuroendocrine Tumors through Epigenetic Control of the Membrane Metallo-Endopeptidase.
Volume: 77
Issue: 2
Pages: 401-411
Publication  
First Author: Jiang X
Year: 2014
Journal: Nat Commun
Title: Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours.
Volume: 5
Pages: 5809
Publication
First Author: Xu B
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Menin promotes hepatocellular carcinogenesis and epigenetically up-regulates Yap1 transcription.
Volume: 110
Issue: 43
Pages: 17480-5
Publication
First Author: Dreijerink KM
Year: 2009
Journal: Mol Cell Biol
Title: The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates peroxisome proliferator-activated receptor gamma-dependent adipocyte differentiation.
Volume: 29
Issue: 18
Pages: 5060-9
Publication
First Author: Cao Y
Year: 2009
Journal: Mol Cell Biol
Title: Nuclear-cytoplasmic shuttling of menin regulates nuclear translocation of {beta}-catenin.
Volume: 29
Issue: 20
Pages: 5477-87
Publication
First Author: Maruyama K
Year: 1999
Journal: Mol Cell Endocrinol
Title: Structure and distribution of rat menin mRNA.
Volume: 156
Issue: 1-2
Pages: 25-33
Publication
First Author: Crabtree JS
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors.
Volume: 98
Issue: 3
Pages: 1118-23
Publication
First Author: Lee S
Year: 2018
Journal: Oncogene
Title: Deletion of Menin in craniofacial osteogenic cells in mice elicits development of mandibular ossifying fibroma.
Volume: 37
Issue: 5
Pages: 616-626
Publication
First Author: Crabtree JS
Year: 2003
Journal: Mol Cell Biol
Title: Of mice and MEN1: Insulinomas in a conditional mouse knockout.
Volume: 23
Issue: 17
Pages: 6075-85
Publication
First Author: Seigne C
Year: 2013
Journal: J Pathol
Title: High incidence of mammary intraepithelial neoplasia development in Men1-disrupted murine mammary glands.
Volume: 229
Issue: 4
Pages: 546-58
Publication
First Author: Harding B
Year: 2009
Journal: Endocr Relat Cancer
Title: Multiple endocrine neoplasia type 1 knockout mice develop parathyroid, pancreatic, pituitary and adrenal tumours with hypercalcaemia, hypophosphataemia and hypercorticosteronaemia.
Volume: 16
Issue: 4
Pages: 1313-27
Publication
First Author: Walls GV
Year: 2012
Journal: Endocrinology
Title: Proliferation rates of multiple endocrine neoplasia type 1 (MEN1)-associated tumors.
Volume: 153
Issue: 11
Pages: 5167-79
Publication
First Author: Maillard I
Year: 2009
Journal: Blood
Title: Menin regulates the function of hematopoietic stem cells and lymphoid progenitors.
Volume: 113
Issue: 8
Pages: 1661-9
Publication
First Author: Scacheri PC
Year: 2004
Journal: Mamm Genome
Title: Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1.
Volume: 15
Issue: 11
Pages: 872-7
Publication
First Author: Smith TL
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: AAVP displaying octreotide for ligand-directed therapeutic transgene delivery in neuroendocrine tumors of the pancreas.
Volume: 113
Issue: 9
Pages: 2466-71
Publication
First Author: Shen HC
Year: 2010
Journal: Endocrinology
Title: Multiple endocrine neoplasia type 1 deletion in pancreatic alpha-cells leads to development of insulinomas in mice.
Volume: 151
Issue: 8
Pages: 4024-30
Publication
First Author: La P
Year: 2007
Journal: J Biol Chem
Title: Menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1.
Volume: 282
Issue: 43
Pages: 31332-40
Publication  
First Author: Vijayakurup V
Year: 2022
Journal: JCI Insight
Title: Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival.
Volume: 7
Issue: 19
Publication
First Author: Loffler KA
Year: 2007
Journal: Int J Cancer
Title: Broad tumor spectrum in a mouse model of multiple endocrine neoplasia type 1.
Volume: 120
Issue: 2
Pages: 259-67
Publication
First Author: Scacheri PC
Year: 2001
Journal: Genesis
Title: Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice.
Volume: 30
Issue: 4
Pages: 259-63
Publication
First Author: Manickam P
Year: 2000
Journal: Mamm Genome
Title: Isolation, characterization, expression and functional analysis of the zebrafish ortholog of MEN1.
Volume: 11
Issue: 6
Pages: 448-54
Publication
First Author: Aziz A
Year: 2009
Journal: Dev Biol
Title: Menin expression modulates mesenchymal cell commitment to the myogenic and osteogenic lineages.
Volume: 332
Issue: 1
Pages: 116-30
Publication
First Author: Hamze Z
Year: 2013
Journal: Endocr Relat Cancer
Title: Altered MENIN expression disrupts the MAFA differentiation pathway in insulinoma.
Volume: 20
Issue: 6
Pages: 833-48
Publication
First Author: Elvis-Offiah UB
Year: 2023
Journal: FASEB J
Title: MENIN-mediated regulation of gastrin gene expression and its role in gastrinoma development.
Volume: 37
Issue: 5
Pages: e22913
Publication
First Author: Hughes CM
Year: 2004
Journal: Mol Cell
Title: Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.
Volume: 13
Issue: 4
Pages: 587-97
Publication
First Author: Bassett JH
Year: 1999
Journal: J Bone Miner Res
Title: Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, men1.
Volume: 14
Issue: 1
Pages: 3-10
Publication
First Author: Lin W
Year: 2016
Journal: Cancer Biol Ther
Title: Kmt2a cooperates with menin to suppress tumorigenesis in mouse pancreatic islets.
Volume: 17
Issue: 12
Pages: 1274-1281
Publication
First Author: Veniaminova NA
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia.
Volume: 303
Issue: 6
Pages: G752-64
Publication
First Author: Karnik SK
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.
Volume: 102
Issue: 41
Pages: 14659-64
Publication
First Author: Modali SD
Year: 2015
Journal: Mol Endocrinol
Title: Epigenetic regulation of the lncRNA MEG3 and its target c-MET in pancreatic neuroendocrine tumors.
Volume: 29
Issue: 2
Pages: 224-37
Publication
First Author: Novotny E
Year: 2009
Journal: Mech Dev
Title: In vitro hematopoietic differentiation of mouse embryonic stem cells requires the tumor suppressor menin and is mediated by Hoxa9.
Volume: 126
Issue: 7
Pages: 517-22
Publication
First Author: La P
Year: 2004
Journal: Endocrinology
Title: Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2.
Volume: 145
Issue: 7
Pages: 3443-50
Publication  
First Author: Xu S
Year: 2012
Journal: Neuroscience
Title: Tumor suppressor menin mediates peripheral nerve injury-induced neuropathic pain through potentiating synaptic plasticity.
Volume: 223
Pages: 473-85
Publication
First Author: Wu Y
Year: 2012
Journal: J Biol Chem
Title: Interplay between menin and K-Ras in regulating lung adenocarcinoma.
Volume: 287
Issue: 47
Pages: 40003-11
Publication
First Author: Nilubol N
Year: 2018
Journal: J Natl Cancer Inst
Title: Novel Dual-Action Targeted Nanomedicine in Mice With Metastatic Thyroid Cancer and Pancreatic Neuroendocrine Tumors.
Volume: 110
Issue: 9
Pages: 1019-1029
Publication
First Author: Huang J
Year: 2012
Journal: Nature
Title: The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Volume: 482
Issue: 7386
Pages: 542-6
Publication
First Author: Chen YX
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: The tumor suppressor menin regulates hematopoiesis and myeloid transformation by influencing Hox gene expression.
Volume: 103
Issue: 4
Pages: 1018-23
Publication
First Author: Libbrecht C
Year: 2021
Journal: Leukemia
Title: Menin is necessary for long term maintenance of meningioma-1 driven leukemia.
Volume: 35
Issue: 5
Pages: 1405-1417