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Search results 1 to 100 out of 113 for Mff

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Hanada Y
Year: 2020
Journal: Nat Commun
Title: MAVS is energized by Mff which senses mitochondrial metabolism via AMPK for acute antiviral immunity.
Volume: 11
Issue: 1
Pages: 5711
Publication
First Author: Otera H
Year: 2010
Journal: J Cell Biol
Title: Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells.
Volume: 191
Issue: 6
Pages: 1141-58
Publication    
First Author: Cha MY
Year: 2018
Journal: PLoS Curr
Title: Removal of the Mitochondrial Fission Factor Mff Exacerbates Neuronal Loss and Neurological Phenotypes in a Huntington's Disease Mouse Model.
Volume: 10
Publication  
First Author: Gonçalves MFF
Year: 2022
Journal: Mol Cell Endocrinol
Title: GATA-1 mutation alters the spermatogonial phase and steroidogenesis in adult mouse testis.
Volume: 542
Pages: 111519
Publication
First Author: Losón OC
Year: 2013
Journal: Mol Biol Cell
Title: Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission.
Volume: 24
Issue: 5
Pages: 659-67
Publication
First Author: Varuzhanyan G
Year: 2021
Journal: Biochim Biophys Acta Gen Subj
Title: Mitochondrial fission factor (Mff) is required for organization of the mitochondrial sheath in spermatids.
Volume: 1865
Issue: 5
Pages: 129845
Publication
First Author: Takeichi Y
Year: 2021
Journal: Diabetologia
Title: Non-alcoholic fatty liver disease in mice with hepatocyte-specific deletion of mitochondrial fission factor.
Volume: 64
Issue: 9
Pages: 2092-2107
Publication
First Author: Chen H
Year: 2015
Journal: J Cell Biol
Title: Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy.
Volume: 211
Issue: 4
Pages: 795-805
Publication
First Author: Osellame LD
Year: 2016
Journal: J Cell Sci
Title: Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission.
Volume: 129
Issue: 11
Pages: 2170-81
Publication  
First Author: Jin Q
Year: 2018
Journal: Redox Biol
Title: DUSP1 alleviates cardiac ischemia/reperfusion injury by suppressing the Mff-required mitochondrial fission and Bnip3-related mitophagy via the JNK pathways.
Volume: 14
Pages: 576-587
Publication  
First Author: Zhou H
Year: 2017
Journal: J Am Heart Assoc
Title: Mff-Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS-Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation-Involved mPTP Opening.
Volume: 6
Issue: 3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lee J
Year: 2018
Journal: Endocrinology
Title: A Genetic Interaction Map of Insulin Production Identifies Mfi as an Inhibitor of Mitochondrial Fission.
Volume: 159
Issue: 9
Pages: 3321-3330
Publication    
First Author: Rojansky R
Year: 2016
Journal: Elife
Title: Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1.
Volume: 5
Publication
First Author: Zhao Y
Year: 2019
Journal: Nat Commun
Title: ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.
Volume: 10
Issue: 1
Pages: 1371
Publication
First Author: Dixit E
Year: 2010
Journal: Cell
Title: Peroxisomes are signaling platforms for antiviral innate immunity.
Volume: 141
Issue: 4
Pages: 668-81
Publication
First Author: Ishihara T
Year: 2015
Journal: Mol Cell Biol
Title: Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development.
Volume: 35
Issue: 1
Pages: 211-23
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Author
Publication
First Author: Hammerschmidt P
Year: 2019
Journal: Cell
Title: CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.
Volume: 177
Issue: 6
Pages: 1536-1552.e23
Publication
First Author: Palmer CS
Year: 2013
Journal: J Biol Chem
Title: Adaptor proteins MiD49 and MiD51 can act independently of Mff and Fis1 in Drp1 recruitment and are specific for mitochondrial fission.
Volume: 288
Issue: 38
Pages: 27584-93
Publication
First Author: Gandre-Babbe S
Year: 2008
Journal: Mol Biol Cell
Title: The novel tail-anchored membrane protein Mff controls mitochondrial and peroxisomal fission in mammalian cells.
Volume: 19
Issue: 6
Pages: 2402-12
Protein Domain
Type: Domain
Description: This entry represents a domain found in mitochondrial fission factor (Mff) and at the C terminus of FATE1. This domain has a predicted transmembrane segment preceded by a coiled-coil region. Despite their similarity in the C terminus, FATE1 lacks a Mff-similar N-terminal domain that is essential for interaction of Mff with the dynamin-related GTPase Drp1, which mediates mitochondrial fission. Instead, FATE1 is involved in the regulation of ER-mitochondria distance and Ca(2+) uptake by mitochondria [].
Protein
Organism: Mus musculus/domesticus
Length: 291  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 243  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 220  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 316  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 340  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 137  
Fragment?: true
Publication
First Author: Palmer CS
Year: 2011
Journal: EMBO Rep
Title: MiD49 and MiD51, new components of the mitochondrial fission machinery.
Volume: 12
Issue: 6
Pages: 565-73
Publication
First Author: Bartsakoulia M
Year: 2018
Journal: Hum Mol Genet
Title: A novel mechanism causing imbalance of mitochondrial fusion and fission in human myopathies.
Volume: 27
Issue: 7
Pages: 1186-1195
Publication
First Author: Chen KH
Year: 2018
Journal: Circulation
Title: Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Volume: 138
Issue: 3
Pages: 287-304
Publication
First Author: Kalia R
Year: 2018
Journal: Nature
Title: Structural basis of mitochondrial receptor binding and constriction by DRP1.
Volume: 558
Issue: 7710
Pages: 401-405
Protein Domain
Type: Family
Description: This entry represents the mitochondrial dynamics protein MID49/MID51. Most members of this protein family contain a Mab-21 domain and are found in chordates.In humans, MID49 and MID51 are outer membrane proteins involved in the regulation of mitochondrial organisation and required for mitochondrial fission by promoting the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. They also regulate DNM1L GTPase activity [, , , , ]. Deregulation of these proteins has been linked to human diseases such as pulmonary arterial hypertension [].
Publication
First Author: D'Amico D
Year: 2019
Journal: Mol Cell
Title: The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging.
Volume: 73
Issue: 4
Pages: 775-787.e10
Publication
First Author: Pangou E
Year: 2021
Journal: Cell Rep
Title: A PKD-MFF signaling axis couples mitochondrial fission to mitotic progression.
Volume: 35
Issue: 7
Pages: 109129