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Search results 1 to 100 out of 308 for Mfn2

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Boutant M
Year: 2017
Journal: EMBO J
Title: Mfn2 is critical for brown adipose tissue thermogenic function.
Volume: 36
Issue: 11
Pages: 1543-1558
Publication
First Author: Chen H
Year: 2003
Journal: J Cell Biol
Title: Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development.
Volume: 160
Issue: 2
Pages: 189-200
Publication
First Author: Chen W
Year: 2020
Journal: Stem Cell Reports
Title: MFN2 Plays a Distinct Role from MFN1 in Regulating Spermatogonial Differentiation.
Volume: 14
Issue: 5
Pages: 803-817
Publication  
First Author: Han S
Year: 2020
Journal: Cells
Title: Mfn2 Ablation in the Adult Mouse Hippocampus and Cortex Causes Neuronal Death.
Volume: 9
Issue: 1
Publication
First Author: Hu L
Year: 2019
Journal: Theranostics
Title: Targeting mitochondrial dynamics by regulating Mfn2 for therapeutic intervention in diabetic cardiomyopathy.
Volume: 9
Issue: 13
Pages: 3687-3706
Publication
First Author: Muñoz JP
Year: 2013
Journal: EMBO J
Title: Mfn2 modulates the UPR and mitochondrial function via repression of PERK.
Volume: 32
Issue: 17
Pages: 2348-61
Publication
First Author: Kim HJ
Year: 2015
Journal: Biochem Biophys Res Commun
Title: HDAC6 maintains mitochondrial connectivity under hypoxic stress by suppressing MARCH5/MITOL dependent MFN2 degradation.
Volume: 464
Issue: 4
Pages: 1235-40
Publication
First Author: Li J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Lysocardiolipin acyltransferase 1 (ALCAT1) controls mitochondrial DNA fidelity and biogenesis through modulation of MFN2 expression.
Volume: 109
Issue: 18
Pages: 6975-80
Publication
First Author: Detmer SA
Year: 2007
Journal: J Cell Biol
Title: Complementation between mouse Mfn1 and Mfn2 protects mitochondrial fusion defects caused by CMT2A disease mutations.
Volume: 176
Issue: 4
Pages: 405-14
Publication
First Author: Jiang S
Year: 2018
Journal: Mol Neurodegener
Title: Mfn2 ablation causes an oxidative stress response and eventual neuronal death in the hippocampus and cortex.
Volume: 13
Issue: 1
Pages: 5
Publication
First Author: Mahdaviani K
Year: 2017
Journal: EMBO Rep
Title: Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis.
Volume: 18
Issue: 7
Pages: 1123-1138
Publication
First Author: Sebastián D
Year: 2016
Journal: EMBO J
Title: Mfn2 deficiency links age-related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway.
Volume: 35
Issue: 15
Pages: 1677-93
Publication  
First Author: Lee YS
Year: 2018
Journal: Cancer Lett
Title: Deficiency of parkin suppresses melanoma tumor development and metastasis through inhibition of MFN2 ubiquitination.
Volume: 433
Pages: 156-164
Publication
First Author: Pham AH
Year: 2012
Journal: Hum Mol Genet
Title: Loss of Mfn2 results in progressive, retrograde degeneration of dopaminergic neurons in the nigrostriatal circuit.
Volume: 21
Issue: 22
Pages: 4817-26
Publication  
First Author: Vadnais ML
Year: 2014
Journal: Cilia
Title: Mitochondrial fusion protein MFN2 interacts with the mitostatin-related protein MNS1 required for mouse sperm flagellar structure and function.
Volume: 3
Pages: 5
Publication
First Author: Franco A
Year: 2016
Journal: Nature
Title: Correcting mitochondrial fusion by manipulating mitofusin conformations.
Volume: 540
Issue: 7631
Pages: 74-79
Publication    
First Author: Franco A
Year: 2020
Journal: Elife
Title: Burst mitofusin activation reverses neuromuscular dysfunction in murine CMT2A.
Volume: 9
Publication
First Author: Bannerman P
Year: 2016
Journal: PLoS One
Title: Mice Hemizygous for a Pathogenic Mitofusin-2 Allele Exhibit Hind Limb/Foot Gait Deficits and Phenotypic Perturbations in Nerve and Muscle.
Volume: 11
Issue: 12
Pages: e0167573
Publication
First Author: Guillet V
Year: 2011
Journal: FASEB J
Title: Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.
Volume: 25
Issue: 5
Pages: 1618-27
Publication
First Author: Mancini G
Year: 2019
Journal: Cell Rep
Title: Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight.
Volume: 26
Issue: 11
Pages: 2849-2858.e4
Publication
First Author: Zhao J
Year: 2018
Journal: Sci Rep
Title: Embryonic Surface Ectoderm-specific Mitofusin 2 Conditional Knockout Induces Congenital Cataracts in Mice.
Volume: 8
Issue: 1
Pages: 1522
Publication
First Author: Sebastián D
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Volume: 109
Issue: 14
Pages: 5523-8
Publication
First Author: Mourier A
Year: 2015
Journal: J Cell Biol
Title: Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels.
Volume: 208
Issue: 4
Pages: 429-42
Publication
First Author: Wang L
Year: 2018
Journal: Cell Metab
Title: Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles.
Volume: 28
Issue: 3
Pages: 400-414.e8
Publication
First Author: Yue W
Year: 2014
Journal: Cell Res
Title: A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30.
Volume: 24
Issue: 4
Pages: 482-96
Publication  
First Author: Zhou Y
Year: 2019
Journal: J Clin Invest
Title: Restoring mitofusin balance prevents axonal degeneration in a Charcot-Marie-Tooth type 2A model.
Volume: 130
Pages: 1756-1771
Publication
First Author: Debattisti V
Year: 2014
Journal: J Cell Biol
Title: Reduction of endoplasmic reticulum stress attenuates the defects caused by Drosophila mitofusin depletion.
Volume: 204
Issue: 3
Pages: 303-12
Publication
First Author: McFie PJ
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Endoplasmic reticulum-mitochondrial interaction mediated by mitofusin-1 or mitofusin-2 is not required for lipid droplet formation or adipocyte differentiation.
Volume: 478
Issue: 1
Pages: 392-397
Publication  
First Author: Hou X
Year: 2019
Journal: Redox Biol
Title: Mitofusin1 in oocyte is essential for female fertility.
Volume: 21
Pages: 101110
Publication
First Author: Schneeberger M
Year: 2013
Journal: Cell
Title: Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Volume: 155
Issue: 1
Pages: 172-87
Publication
First Author: Misko A
Year: 2010
Journal: J Neurosci
Title: Mitofusin 2 is necessary for transport of axonal mitochondria and interacts with the Miro/Milton complex.
Volume: 30
Issue: 12
Pages: 4232-40
Publication
First Author: Chen KH
Year: 2014
Journal: FASEB J
Title: Role of mitofusin 2 (Mfn2) in controlling cellular proliferation.
Volume: 28
Issue: 1
Pages: 382-94
Publication
First Author: Honda S
Year: 2005
Journal: J Cell Sci
Title: Mutational analysis of action of mitochondrial fusion factor mitofusin-2.
Volume: 118
Issue: Pt 14
Pages: 3153-61
Publication
First Author: Zhang Y
Year: 2013
Journal: Mol Cell Endocrinol
Title: MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2.
Volume: 381
Issue: 1-2
Pages: 230-40
Publication
First Author: Kawalec M
Year: 2015
Journal: PLoS One
Title: Mitofusin 2 Deficiency Affects Energy Metabolism and Mitochondrial Biogenesis in MEF Cells.
Volume: 10
Issue: 7
Pages: e0134162
Publication  
First Author: Zhou W
Year: 2020
Journal: J Cell Sci
Title: Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton.
Volume: 133
Issue: 17
Publication
First Author: Gall JM
Year: 2012
Journal: PLoS One
Title: Role of mitofusin 2 in the renal stress response.
Volume: 7
Issue: 1
Pages: e31074
Publication
First Author: Soriano FX
Year: 2006
Journal: Diabetes
Title: Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-gamma coactivator-1 alpha, estrogen-related receptor-alpha, and mitofusin 2.
Volume: 55
Issue: 6
Pages: 1783-91
Publication
First Author: Segalés J
Year: 2013
Journal: Am J Physiol Endocrinol Metab
Title: A form of mitofusin 2 (Mfn2) lacking the transmembrane domains and the COOH-terminal end stimulates metabolism in muscle and liver cells.
Volume: 305
Issue: 10
Pages: E1208-21
Publication
First Author: Filadi R
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Mitofusin 2 ablation increases endoplasmic reticulum-mitochondria coupling.
Volume: 112
Issue: 17
Pages: E2174-81
Publication
First Author: Tur J
Year: 2020
Journal: Cell Rep
Title: Mitofusin 2 in Macrophages Links Mitochondrial ROS Production, Cytokine Release, Phagocytosis, Autophagy, and Bactericidal Activity.
Volume: 32
Issue: 8
Pages: 108079
Publication
First Author: Filadi R
Year: 2016
Journal: Cell Rep
Title: Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2.
Volume: 15
Issue: 10
Pages: 2226-2238
Publication
First Author: Sugiura A
Year: 2013
Journal: Mol Cell
Title: MITOL regulates endoplasmic reticulum-mitochondria contacts via Mitofusin2.
Volume: 51
Issue: 1
Pages: 20-34
Publication
First Author: Harland M
Year: 2020
Journal: J Neurosci
Title: Neuronal Mitochondria Modulation of LPS-Induced Neuroinflammation.
Volume: 40
Issue: 8
Pages: 1756-1765
Publication
First Author: Gong G
Year: 2015
Journal: Science
Title: Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice.
Volume: 350
Issue: 6265
Pages: aad2459
Publication
First Author: Dietrich MO
Year: 2013
Journal: Cell
Title: Mitochondrial dynamics controlled by mitofusins regulate Agrp neuronal activity and diet-induced obesity.
Volume: 155
Issue: 1
Pages: 188-99
Publication
First Author: Song M
Year: 2014
Journal: Circ Res
Title: Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy.
Volume: 115
Issue: 3
Pages: 348-53
Publication
First Author: Chen Y
Year: 2012
Journal: Circ Res
Title: Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.
Volume: 111
Issue: 7
Pages: 863-75
Publication
First Author: Ngoh GA
Year: 2012
Journal: J Biol Chem
Title: Loss of mitofusin 2 promotes endoplasmic reticulum stress.
Volume: 287
Issue: 24
Pages: 20321-32
Publication
First Author: Koshiba T
Year: 2011
Journal: Sci Signal
Title: Mitochondrial membrane potential is required for MAVS-mediated antiviral signaling.
Volume: 4
Issue: 158
Pages: ra7
Publication
First Author: Chen Y
Year: 2013
Journal: Science
Title: PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria.
Volume: 340
Issue: 6131
Pages: 471-5
Publication
First Author: Chung KP
Year: 2019
Journal: Nat Commun
Title: Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.
Volume: 10
Issue: 1
Pages: 3390
Publication
First Author: Yasukawa K
Year: 2009
Journal: Sci Signal
Title: Mitofusin 2 inhibits mitochondrial antiviral signaling.
Volume: 2
Issue: 84
Pages: ra47
Publication
First Author: Gautier CA
Year: 2016
Journal: Hum Mol Genet
Title: The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations.
Volume: 25
Issue: 14
Pages: 2972-2984
Publication
First Author: Luchsinger LL
Year: 2016
Journal: Nature
Title: Mitofusin 2 maintains haematopoietic stem cells with extensive lymphoid potential.
Volume: 529
Issue: 7587
Pages: 528-31
Publication
First Author: Zhao T
Year: 2012
Journal: J Biol Chem
Title: Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes.
Volume: 287
Issue: 28
Pages: 23615-25
Publication  
First Author: Kuo IY
Year: 2019
Journal: Sci Signal
Title: Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.
Volume: 12
Issue: 580
Publication
First Author: Brooks C
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Bak regulates mitochondrial morphology and pathology during apoptosis by interacting with mitofusins.
Volume: 104
Issue: 28
Pages: 11649-54
Publication
First Author: de Brito OM
Year: 2009
Journal: Mitochondrion
Title: Mitofusin-2 regulates mitochondrial and endoplasmic reticulum morphology and tethering: the role of Ras.
Volume: 9
Issue: 3
Pages: 222-6
Publication
First Author: Chen H
Year: 2007
Journal: Cell
Title: Mitochondrial fusion protects against neurodegeneration in the cerebellum.
Volume: 130
Issue: 3
Pages: 548-62
Publication
First Author: Karbowski M
Year: 2006
Journal: Nature
Title: Role of Bax and Bak in mitochondrial morphogenesis.
Volume: 443
Issue: 7112
Pages: 658-62
Publication  
First Author: Nivison MP
Year: 2017
Journal: Exp Neurol
Title: Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression.
Volume: 296
Pages: 49-61
Publication
First Author: Lee S
Year: 2012
Journal: Hum Mol Genet
Title: Mitofusin 2 is necessary for striatal axonal projections of midbrain dopamine neurons.
Volume: 21
Issue: 22
Pages: 4827-35
Publication
First Author: Liesa M
Year: 2008
Journal: PLoS One
Title: Mitochondrial fusion is increased by the nuclear coactivator PGC-1beta.
Volume: 3
Issue: 10
Pages: e3613
Publication
First Author: Hong Y
Year: 2020
Journal: Cell Death Differ
Title: RNA binding protein HuD contributes to β-cell dysfunction by impairing mitochondria dynamics.
Volume: 27
Issue: 5
Pages: 1633-1643
Publication
First Author: Chen H
Year: 2005
Journal: J Biol Chem
Title: Disruption of fusion results in mitochondrial heterogeneity and dysfunction.
Volume: 280
Issue: 28
Pages: 26185-92
Publication
First Author: Uo T
Year: 2009
Journal: Exp Neurol
Title: Drp1 levels constitutively regulate mitochondrial dynamics and cell survival in cortical neurons.
Volume: 218
Issue: 2
Pages: 274-85
Publication  
First Author: Bhatia D
Year: 2019
Journal: JCI Insight
Title: Mitophagy-dependent macrophage reprogramming protects against kidney fibrosis.
Volume: 4
Issue: 23
Publication
First Author: Ballard A
Year: 2020
Journal: J Biol Chem
Title: The tethering function of mitofusin2 controls osteoclast differentiation by modulating the Ca2+-NFATc1 axis.
Volume: 295
Issue: 19
Pages: 6629-6640
Publication
First Author: Chen Y
Year: 2011
Journal: Circ Res
Title: Mitochondrial fusion is essential for organelle function and cardiac homeostasis.
Volume: 109
Issue: 12
Pages: 1327-31
Publication
First Author: Drew BG
Year: 2014
Journal: Diabetes
Title: HSP72 is a mitochondrial stress sensor critical for Parkin action, oxidative metabolism, and insulin sensitivity in skeletal muscle.
Volume: 63
Issue: 5
Pages: 1488-505
Publication
First Author: Cleland MM
Year: 2011
Journal: Cell Death Differ
Title: Bcl-2 family interaction with the mitochondrial morphogenesis machinery.
Volume: 18
Issue: 2
Pages: 235-47
Publication
First Author: Li Y
Year: 2009
Journal: J Mol Cell Cardiol
Title: Peroxisome proliferator-activated receptor delta regulates mitofusin 2 expression in the heart.
Volume: 46
Issue: 6
Pages: 876-82
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Schneeberger M
Year: 2015
Journal: Cell Rep
Title: Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis.
Volume: 12
Issue: 3
Pages: 361-70
Publication
First Author: Singaravelu K
Year: 2011
Journal: J Biol Chem
Title: Mitofusin 2 regulates STIM1 migration from the Ca2+ store to the plasma membrane in cells with depolarized mitochondria.
Volume: 286
Issue: 14
Pages: 12189-201
Publication
First Author: Jiang GJ
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Expression of HSG is essential for mouse blastocyst formation.
Volume: 335
Issue: 2
Pages: 351-5
Publication
First Author: Lopez-Bigas N
Year: 2008
Journal: Mol Cell
Title: Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.
Volume: 31
Issue: 4
Pages: 520-30