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Search results 1 to 93 out of 93 for Mia2

0.049s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Pitman JL
Year: 2011
Journal: J Lipid Res
Title: Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.
Volume: 52
Issue: 10
Pages: 1775-86
Publication
First Author: Fan J
Year: 2017
Journal: J Cell Biol
Title: cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.
Volume: 216
Issue: 12
Pages: 4153-4164
Publication
First Author: Bosserhoff AK
Year: 2004
Journal: Gene Expr Patterns
Title: Characterization and expression pattern of the novel MIA homolog TANGO.
Volume: 4
Issue: 4
Pages: 473-9
Publication
First Author: Zhang F
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: cTAGE5/MEA6 plays a critical role in neuronal cellular components trafficking and brain development.
Volume: 115
Issue: 40
Pages: E9449-E9458
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication  
First Author: Wang XT
Year: 2020
Journal: Front Cell Dev Biol
Title: Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance.
Volume: 8
Pages: 627146
Publication  
First Author: Wang XT
Year: 2019
Journal: Front Cell Neurosci
Title: MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.
Volume: 13
Pages: 250
Publication
First Author: Wang Y
Year: 2016
Journal: Cell Res
Title: Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.
Volume: 26
Issue: 7
Pages: 787-804
GXD Expression      
Probe: MGI:3797252
Assay Type: RT-PCR
Annotation Date: 2008-07-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672820
Stage: TS20
Assay Id: MGI:3797258
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6111889
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6111914
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6111889
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6111914
Age: embryonic day 18.5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6111889
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6111914
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3524981
Assay Type: RNA in situ
Annotation Date: 2005-02-01
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1684620
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:3524982
Age: embryonic day 12.5
Image: 4B
Specimen Label: 4B
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4424792
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540754
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Lin S
Year: 2008
Journal: Dev Biol
Title: Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.
Volume: 316
Issue: 2
Pages: 441-55
Publication
First Author: Moser M
Year: 2002
Journal: Mol Cell Biol
Title: Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.
Volume: 22
Issue: 5
Pages: 1438-45
Publication
First Author: Jin L
Year: 2020
Journal: Nat Commun
Title: STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells.
Volume: 11
Issue: 1
Pages: 5941
Publication      
First Author: The Jackson Laboratory DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX Interspecific Backcross BSS and BSB Public Mapping Data
Publication
First Author: Brady KP
Year: 1997
Journal: Genome Res
Title: Genetic mapping of 262 loci derived from expressed sequences in a murine interspecific cross using single-strand conformational polymorphism analysis.
Volume: 7
Issue: 11
Pages: 1085-93
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication
First Author: Bosserhoff AK
Year: 2003
Journal: J Biol Chem
Title: Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.
Volume: 278
Issue: 17
Pages: 15225-31
Publication
First Author: Hellerbrand C
Year: 2008
Journal: Gut
Title: The novel gene MIA2 acts as a tumour suppressor in hepatocellular carcinoma.
Volume: 57
Issue: 2
Pages: 243-51
Protein
Organism: Mus musculus/domesticus
Length: 1396  
Fragment?: false
Publication
First Author: Hellerbrand C
Year: 2005
Journal: Liver Int
Title: In situ expression patterns of melanoma inhibitory activity 2 in healthy and diseased livers.
Volume: 25
Issue: 2
Pages: 357-66
Protein Domain
Type: Domain
Description: MIA2 is expressed specifically in hepatocytes and its expression is controlled by hepatocyte nuclear factor 1 binding sites in the MIA2 promoter [, ]. It inhibits the growth and invasion of hepatocellular carcinomas (HCC) and may act as a tumour suppressor []. A mutation in MIA2 in mice resulted in reduced cholesterol and triglycerides. Since MIA2 localizes to ER exit sites, it may function as an ER-to-Golgi trafficking protein that regulates lipid metabolism []. MIA2 contains an N-terminal SH3-like domain, similar to MIA.MIA (melanoma inhibitory activity) family members include MIA, MIAL, MIA2, and MIA3 (also called TANGO). MIA was found to be strongly expressed and secreted by malignant melanomas. It contains a domain that adopts a Src Homology 3 (SH3) domain-like fold; however, it contains an additional antiparallel beta sheet and two disulfide bonds compared to classical SH3 domains. Unlike classical SH3 domains, MIA does not bind proline-rich ligands [, ].
Allele
Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Biocytogen LLC
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Epitope tag, Humanized sequence, Inserted expressed sequence
Publication
First Author: Stoll R
Year: 2008
Journal: Curr Protein Pept Sci
Title: Extracellular SH3 domain containing proteins--features of a new protein family.
Volume: 9
Issue: 3
Pages: 221-6
Publication
First Author: Stoll R
Year: 2003
Journal: Protein Sci
Title: Backbone dynamics of the human MIA protein studied by (15)N NMR relaxation: implications for extended interactions of SH3 domains.
Volume: 12
Issue: 3
Pages: 510-9
Publication
First Author: Santos AJ
Year: 2016
Journal: J Cell Biol
Title: TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.
Volume: 213
Issue: 3
Pages: 343-54