| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takagi M |
| Year: |
2001 |
| Journal: |
J Biol Chem |
| Title: |
A novel nucleolar protein, NIFK, interacts with the forkhead associated domain of Ki-67 antigen in mitosis. |
| Volume: |
276 |
| Issue: |
27 |
| Pages: |
25386-91 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287821 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 12.5 |
| Image: |
1D1 |
| Note: |
Mki67 is a proliferation marker. |
| Specimen Label: |
1D1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287822 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 14.5 |
| Image: |
1D2 |
| Note: |
Mki67 is a proliferation marker. |
| Specimen Label: |
1D2 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3287824 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 16.5 |
| Image: |
1D3 |
| Note: |
Mki67 is a proliferation marker. |
| Specimen Label: |
1D3 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3288121 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 12.5 |
| Image: |
1D1 |
| Note: |
Mki67 is a proliferation marker. |
| Specimen Label: |
1D1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3288122 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 14.5 |
| Image: |
1D2 |
| Note: |
Mki67 is a proliferation marker. |
| Specimen Label: |
1D2 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3288124 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 16.5 |
| Image: |
1D3 |
| Note: |
Mki67 is a proliferation marker. |
| Specimen Label: |
1D3 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3747020 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 12.5 |
| Image: |
S7C |
| Note: |
Mki67 expression was detected in cycling cells. |
| Specimen Label: |
S7C |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3284223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7444001 |
| Age: |
embryonic day 15.5 |
| Image: |
S4A Ki67 KO |
| Note: |
Smaller proportion BrdU-labeled cells co-expressing Mki67 |
| Specimen Label: |
S4A Ki67 KO |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3747023 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 15.5 |
| Image: |
9M' |
| Note: |
Mki67 expression was detected in cycling cells. |
| Specimen Label: |
9M' |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8409356 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-09-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733724 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:8409551 |
| Age: |
embryonic day 16.5 |
| Image: |
2A cTnt-Cre; Bcl11b f/f |
| Note: |
Percentage of Mki67 expressing cardiomyocytes significantly reduced compared to control. |
| Specimen Label: |
2A cTnt-Cre; Bcl11b f/f |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8409356 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2026-09-10 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1733724 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:8409551 |
| Age: |
embryonic day 16.5 |
| Image: |
2A cTnt-Cre; Bcl11b f/f |
| Note: |
Percentage of Mki67 expressing cardiomyocytes significantly reduced compared to control. |
| Specimen Label: |
2A cTnt-Cre; Bcl11b f/f |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7448888 |
| Age: |
embryonic day 10.5 |
| Image: |
S4A Ctrl |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4A Ctrl |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268817 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:7448888 |
| Age: |
embryonic day 10.5 |
| Image: |
S4A Ctrl |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4A Ctrl |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7448888 |
| Age: |
embryonic day 11.5 |
| Image: |
S4B Ctrl E11.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7448888 |
| Age: |
embryonic day 12.5 |
| Image: |
S4B Ctrl E12.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E12.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8235081 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-08-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616415 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8235159 |
| Age: |
embryonic day 9.5 |
| Image: |
3Ac |
| Note: |
Mki67 (a late G1-M phase marker) labels all dividing cells. |
| Specimen Label: |
3Ac |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8235081 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-08-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616417 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:8235159 |
| Age: |
embryonic day 10.5 |
| Image: |
3Ag |
| Note: |
Mki67 (a late G1-M phase marker) labels all dividing cells. |
| Specimen Label: |
3Ag |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754724 |
| Pattern: |
Not Specified |
| Stage: |
TS24 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 16.5 |
| Image: |
5E miR-9-2 +/+; miR9-3 +/+ |
| Note: |
Mki67 expression was detected in cycling cells in the pallium. |
| Specimen Label: |
5E miR-9-2 +/+; miR9-3 +/+ |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754725 |
| Pattern: |
Not Specified |
| Stage: |
TS25 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 17.5 |
| Image: |
5G miR-9-2 +/+; miR9-3 +/+ E17.5 |
| Note: |
Mki67 expression was detected in cycling cells in the pallium. |
| Specimen Label: |
5G miR-9-2 +/+; miR9-3 +/+ E17.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754726 |
| Pattern: |
Not Specified |
| Stage: |
TS26 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 18.5 |
| Image: |
5G miR-9-2 +/+; miR9-3 +/+ E18.5 |
| Note: |
Mki67 expression was detected in cycling cells in the pallium. |
| Specimen Label: |
5G miR-9-2 +/+; miR9-3 +/+ E18.5 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6382931 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3289726 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:8250581 |
| Age: |
embryonic day 18.5 |
| Image: |
1D4 |
| Note: |
Mki67 was expressed only in regions near the cervical loop. |
| Specimen Label: |
1D4 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3270423 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 15.5 |
| Image: |
5A miR-9-2 +/+; miR9-3 +/+ |
| Note: |
Mki67 expression was detected in cycling cells in the pallium. |
| Specimen Label: |
5A miR-9-2 +/+; miR9-3 +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268819 |
| Pattern: |
Regionally restricted |
| Stage: |
TS19 |
| Assay Id: |
MGI:7448888 |
| Age: |
embryonic day 11.5 |
| Image: |
S4B Ctrl E11.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E11.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5792660 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-03-30 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3268820 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:7448888 |
| Age: |
embryonic day 12.5 |
| Image: |
S4B Ctrl E12.5 |
| Note: |
Co-expression of Mki67 and Tnnt2 was detected in proliferating cardiomyocytes. |
| Specimen Label: |
S4B Ctrl E12.5 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7736601 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-10-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1754723 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:7736602 |
| Age: |
embryonic day 15.5 |
| Image: |
5A miR-9-2 +/+; miR9-3 +/+ |
| Note: |
Mki67 expression was detected in cycling cells in the pallium. |
| Specimen Label: |
5A miR-9-2 +/+; miR9-3 +/+ |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8235081 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-08-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616417 |
| Pattern: |
Regionally restricted |
| Stage: |
TS17 |
| Assay Id: |
MGI:8235159 |
| Age: |
embryonic day 10.5 |
| Image: |
3Ah |
| Note: |
Proliferation was enormously increased in the Palladin-/- neural tube as confirmed with Mki67 staining. |
| Specimen Label: |
3Ah |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3057020 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2004-11-18 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1702128 |
| Pattern: |
Not Specified |
| Stage: |
TS28 |
| Assay Id: |
MGI:3057278 |
| Age: |
postnatal year 1 |
|
| Note: |
A marked increase in Mki67 expressing is noted in the knockout. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6454056 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-09-11 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3803620 |
| Pattern: |
Regionally restricted |
| Stage: |
TS20 |
| Assay Id: |
MGI:6454685 |
| Age: |
embryonic day 12.5 |
| Image: |
6C |
| Note: |
Lymphatic endothelial cells expressing Mki67 and Lyve1 were detected in the jugular lymph sac. |
| Specimen Label: |
6C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6194264 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2018-08-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1778721 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:6194373 |
| Age: |
embryonic day 12.5 |
| Image: |
2E,F,H |
| Note: |
Expression was detected in mitotic cells. Some cells were immunopositive for both Mki67 and Olig2. |
| Specimen Label: |
2E,F,H |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7341462 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2022-09-28 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3521627 |
| Pattern: |
Not Specified |
| Stage: |
TS27 |
| Assay Id: |
MGI:7341515 |
| Age: |
postnatal day 3 |
| Image: |
10B |
| Note: |
The proportion of Mki67 positive cells labelled by BrdU was significantly lower than wild type. |
| Specimen Label: |
10B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:8235081 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-08-14 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1616415 |
| Pattern: |
Regionally restricted |
| Stage: |
TS15 |
| Assay Id: |
MGI:8235159 |
| Age: |
embryonic day 9.5 |
| Image: |
3Ad |
| Note: |
Proliferation was enormously increased in the Palladin-/- neural tube as confirmed with Mki67 staining. |
| Specimen Label: |
3Ad |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| UniProt Feature |
| Begin: |
2 |
| Description: |
MKI67 FHA domain-interacting nucleolar phosphoprotein |
| Type: |
chain |
| End: |
317 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6407085 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691322 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:6416293 |
| Age: |
embryonic day 14.5 |
|
| Note: |
The cortical hem was enlarged in the conditional mutant, and the percentage of Mki67 immunolabeled cells was increased at E14.5. |
| Specimen Label: |
not shown E14.5 Nf2;Emx1-Cre (2H) |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6715366 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2025-08-26 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3599825 |
| Pattern: |
Regionally restricted |
| Stage: |
TS25 |
| Assay Id: |
MGI:8238907 |
| Age: |
embryonic day 17.5 |
| Image: |
1K |
| Note: |
Expression was detected in proliferating cells. Insm1 and Mki67 double labeled cells were only very rarely observed. |
| Specimen Label: |
1K |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7608423 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-03-05 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1783721 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7610017 |
| Age: |
embryonic day 13.5 |
| Image: |
S3d |
| Note: |
Increased cell proliferation was indicated by Mki67 immunostaining in the primary vitreous of Tgfb2-/- versus wild type embryos. |
| Specimen Label: |
S3d |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6407085 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2020-05-13 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:6416293 |
| Age: |
embryonic day 15.5 |
| Image: |
2G |
| Note: |
The cortical hem was enlarged in the conditional mutant, and the percentage of Mki67 immunolabeled cells was increased at E15.5. |
| Specimen Label: |
2G |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, African clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pan WA |
| Year: |
2015 |
| Journal: |
RNA Biol |
| Title: |
The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression. |
| Volume: |
12 |
| Issue: |
3 |
| Pages: |
255-67 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
This entry corresponds includes NIFK and similar eukaryotic proteins including SPCC1827.05c, its orthologue from S.pombe and Ribosome biogenesis protein 15 (NOP15) from S.cerevisae [].NIFK, also termed MKI67 FHA domain-interacting nucleolar phosphoprotein, or nucleolar phosphoprotein Nopp34, is a putative RNA-binding protein interacting with the forkhead associated (FHA) domain of pKi-67 antigen in a mitosis-specific and phosphorylation-dependent manner. It is nucleolar in interphase but associates with condensed mitotic chromosomes [, , , , ].NOP15 is involved in the biogenesis of the 60S ribosomal subunit. It is required for pre-rRNA processing and cytokinesis. It associates with the precursors of the 25S and 5.8S rRNAs [, ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Basak O |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy. |
| Volume: |
115 |
| Issue: |
4 |
| Pages: |
E610-E619 |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Magnusson C |
| Year: |
2003 |
| Journal: |
Cell Biol Int |
| Title: |
The nifk gene is widely expressed in mouse tissues and is up-regulated in denervated hind limb muscle. |
| Volume: |
27 |
| Issue: |
6 |
| Pages: |
469-75 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
269
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Verheijen M |
| Year: |
2020 |
| Journal: |
Cell Rep |
| Title: |
Fate Mapping Quantifies the Dynamics of B Cell Development and Activation throughout Life. |
| Volume: |
33 |
| Issue: |
7 |
| Pages: |
108376 |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
zebrafish |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ren C |
| Year: |
2026 |
| Journal: |
Front Cell Dev Biol |
| Title: |
Single-cell RNA sequencing revealed cell heterogeneity in sagittal suture mesenchyme. |
| Volume: |
14 |
|
| Pages: |
1725375 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry corresponds to the RRM domain of NIFK and similar eukaryotic proteins including SPCC1827.05c its orthologue from S.pombe.NIFK, also termed MKI67 FHA domain-interacting nucleolar phosphoprotein, or nucleolar phosphoprotein Nopp34, is a putative RNA-binding protein interacting with the forkhead associated (FHA) domain of pKi-67 antigen in a mitosis-specific and phosphorylation-dependent manner. It is nucleolar in interphase but associates with condensed mitotic chromosomes [, , , , ]. |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Biehl MJ |
| Year: |
2018 |
| Journal: |
Dev Biol |
| Title: |
Cellular fate decisions in the developing female anteroventral periventricular nucleus are regulated by canonical Notch signaling. |
| Volume: |
442 |
| Issue: |
1 |
| Pages: |
87-100 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Kretzschmar K |
| Year: |
2018 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
Profiling proliferative cells and their progeny in damaged murine hearts. |
| Volume: |
115 |
| Issue: |
52 |
| Pages: |
E12245-E12254 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Niethamer TK |
| Year: |
2025 |
| Journal: |
Cell Stem Cell |
| Title: |
Longitudinal single-cell profiles of lung regeneration after viral infection reveal persistent injury-associated cell states. |
| Volume: |
32 |
| Issue: |
2 |
| Pages: |
302-321.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Yee M |
| Year: |
2025 |
| Journal: |
EMBO Mol Med |
| Title: |
Ki-67 promotes inflammatory signaling governing neutrophil recruitment during respiratory infections. |
| Volume: |
17 |
| Issue: |
8 |
| Pages: |
2011-2039 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Harris L |
| Year: |
2021 |
| Journal: |
Cell Stem Cell |
| Title: |
Coordinated changes in cellular behavior ensure the lifelong maintenance of the hippocampal stem cell population. |
| Volume: |
28 |
| Issue: |
5 |
| Pages: |
863-876.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Frumm SM |
| Year: |
2021 |
| Journal: |
Cell Stem Cell |
| Title: |
A Hierarchy of Proliferative and Migratory Keratinocytes Maintains the Tympanic Membrane. |
| Volume: |
28 |
| Issue: |
2 |
| Pages: |
315-330.e5 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liu X |
| Year: |
2021 |
| Journal: |
Nat Commun |
| Title: |
Cell proliferation fate mapping reveals regional cardiomyocyte cell-cycle activity in subendocardial muscle of left ventricle. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
5784 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Saygili Demir C |
| Year: |
2023 |
| Journal: |
J Cell Biol |
| Title: |
Mechanosensitive mTORC1 signaling maintains lymphatic valves. |
| Volume: |
222 |
| Issue: |
6 |
|
|
•
•
•
•
•
|
| Publication |
| First Author: |
Ugur M |
| Year: |
2023 |
| Journal: |
Immunity |
| Title: |
Lymph node medulla regulates the spatiotemporal unfolding of resident dendritic cell networks. |
| Volume: |
56 |
| Issue: |
8 |
| Pages: |
1778-1793.e10 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhao H |
| Year: |
2023 |
| Journal: |
Cell Discov |
| Title: |
Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas. |
| Volume: |
9 |
| Issue: |
1 |
| Pages: |
1 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Chen J |
| Year: |
2022 |
| Journal: |
Mol Neurobiol |
| Title: |
Function of Oncogene Mycn in Adult Neurogenesis and Oligodendrogenesis. |
| Volume: |
59 |
| Issue: |
1 |
| Pages: |
77-92 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gerhardt LMS |
| Year: |
2023 |
| Journal: |
J Am Soc Nephrol |
| Title: |
Lineage Tracing and Single-Nucleus Multiomics Reveal Novel Features of Adaptive and Maladaptive Repair after Acute Kidney Injury. |
| Volume: |
34 |
| Issue: |
4 |
| Pages: |
554-571 |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Domain |
| Description: |
This entry represents eukaryotic proteins that contain a domain of approximately 40 amino acids in length. These proteins are found in association with . There are two conserved sequence motifs: TPVCTP and LERRKS. This domain is found on the human nucleolar protein hNIFK.NIFK, also termed MKI67 FHA domain-interacting nucleolar phosphoprotein, or nucleolar phosphoprotein Nopp34, is a putative RNA-binding protein interacting with the forkhead associated (FHA) domain of pKi-67 antigen in a mitosis-specific and phosphorylation-dependent manner. It is nucleolar in interphase but associates with condensed mitotic chromosomes [, , , , ]. |
|
•
•
•
•
•
|