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Search results 1 to 100 out of 110 for Mlana

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Domain
Type: Family
Description: Melan-A, also known as melanoma antigen recognised by T-cells 1, or MART-1, is a protein that in humans is encoded by the MLANA gene. It is required for the function of the melanosomal matrix protein PMEL17/GP100 and thus plays an important role in regulating mammalian pigmentation []. Melan-A is a member of the MAGE gene family []and is a tumour associated antigen. Clinically, the protein may serve as an anti-cancer vaccine [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 113  
Fragment?: false
Publication
First Author: Hoashi T
Year: 2005
Journal: J Biol Chem
Title: MART-1 is required for the function of the melanosomal matrix protein PMEL17/GP100 and the maturation of melanosomes.
Volume: 280
Issue: 14
Pages: 14006-16
Publication
First Author: Bardliving CL
Year: 2013
Journal: Protein Expr Purif
Title: Process development and production of cGMP grade Melan-A for cancer vaccine clinical trials.
Volume: 92
Issue: 2
Pages: 171-82
Publication
First Author: Chomez P
Year: 2001
Journal: Cancer Res
Title: An overview of the MAGE gene family with the identification of all human members of the family.
Volume: 61
Issue: 14
Pages: 5544-51
Publication
First Author: Aydin IT
Year: 2011
Journal: Genesis
Title: A mart-1::Cre transgenic line induces recombination in melanocytes and retinal pigment epithelium.
Volume: 49
Issue: 5
Pages: 403-9
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Mouriaux F
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Effects of Long-term Serial Passaging on the Characteristics and Properties of Cell Lines Derived From Uveal Melanoma Primary Tumors.
Volume: 57
Issue: 13
Pages: 5288-5301
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 3 C57BL/6J
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 3 Mitf Mi/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 3 Mitf Mi/Mi
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_Mlana_+_+_a_head_40
Specimen Label: sl_Mlana_+_+_a_head_40
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_Mlana_mi_+_a_head_40
Specimen Label: sl_Mlana_mi_+_a_head_40
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_Mlana_mi_mi_a_head_40
Specimen Label: sl_Mlana_mi_mi_a_head_40
Detected: false
Specimen Num: 11
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_MlanA_mi_mi_a_side_16
Specimen Label: sl_MlanA_mi_mi_a_side_16
Detected: false
Specimen Num: 12
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_MlnA_mi_+_a_side_16
Specimen Label: sl_MlnA_mi_+_a_side_16
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_MlanA_+_+_a_side_16
Specimen Label: sl_MlanA_+_+_a_side_16
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 5A Mitf+/+
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1717219
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 5A Mitf Mi/+
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1717219
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 5A Mitf Mi/Mi
Detected: false
Specimen Num: 6
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616919
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_Mlana_+_+_a_head_40
Note: Absent in melanoblasts.
Specimen Label: sl_Mlana_+_+_a_head_40
Detected: false
Specimen Num: 7
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616919
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_Mlana_mi_+_a_head_40
Note: Absent in melanoblasts.
Specimen Label: sl_Mlana_mi_+_a_head_40
Detected: false
Specimen Num: 9
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1616919
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_Mlana_mi_mi_a_head_40
Note: Absent in melanoblasts.
Specimen Label: sl_Mlana_mi_mi_a_head_40
Detected: false
Specimen Num: 11
GXD Expression
Probe: MGI:6456179
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-21
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3639228
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6456591
Age: postnatal adult
Image: 3H (Late)
Note: Abnormal increase in density in dermis in locations concurrent with increased incidence of pigment.
Specimen Label: 3H (Late)
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273519
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Note: Absent in melanoblasts.
Specimen Label: 3 C57BL/6J
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273519
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Note: Absent in melanoblasts.
Specimen Label: 3 Mitf Mi/+
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273519
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Specimen Label: 3 Mitf Mi/Mi
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273519
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_MlanA_+_+_a_side_16
Note: Absent in melanoblasts.
Specimen Label: sl_MlanA_+_+_a_side_16
Detected: false
Specimen Num: 8
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273519
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_MlanA_mi_mi_a_side_16
Note: Absent in melanoblasts.
Specimen Label: sl_MlanA_mi_mi_a_side_16
Detected: false
Specimen Num: 12
GXD Expression  
Probe: MGI:4437036
Assay Type: RNA in situ
Annotation Date: 2010-03-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3273519
Stage: TS19
Assay Id: MGI:4437035
Age: embryonic day 11.5
Image: sl_MlnA_mi_+_a_side_16
Note: Absent in melanoblasts.
Specimen Label: sl_MlnA_mi_+_a_side_16
Detected: false
Specimen Num: 10
GXD Expression
Probe: MGI:6456179
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6456591
Age: postnatal adult
Image: 3H +/+
Note: Expression in dermal melanocytes.
Specimen Label: 3H +/+
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6456179
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6456591
Age: postnatal adult
Image: 3H (Early)
Specimen Label: 3H (Early)
Detected: true
Specimen Num: 2
Publication
First Author: Aydin IT
Year: 2012
Journal: Pigment Cell Melanoma Res
Title: Coat color dilution in mice because of inactivation of the melanoma antigen MART-1.
Volume: 25
Issue: 1
Pages: 37-46
Publication
First Author: Giordano F
Year: 2009
Journal: Hum Mol Genet
Title: The ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and composition.
Volume: 18
Issue: 23
Pages: 4530-45
Publication
First Author: Zhai Y
Year: 1997
Journal: J Immunother
Title: Cloning and characterization of the genes encoding the murine homologues of the human melanoma antigens MART1 and gp100.
Volume: 20
Issue: 1
Pages: 15-25
Publication  
First Author: Sun G
Year: 2020
Journal: Front Genet
Title: Functional Analysis of KIT Gene Structural Mutations Causing the Porcine Dominant White Phenotype Using Genome Edited Mouse Models.
Volume: 11
Pages: 138
Publication
First Author: DiTommaso T
Year: 2014
Journal: PLoS Genet
Title: Keratin 76 is required for tight junction function and maintenance of the skin barrier.
Volume: 10
Issue: 10
Pages: e1004706
Publication
First Author: Loftus SK
Year: 2009
Journal: Pigment Cell Melanoma Res
Title: Comparison of melanoblast expression patterns identifies distinct classes of genes.
Volume: 22
Issue: 5
Pages: 611-22
Publication
First Author: Wright A
Year: 1997
Journal: Mamm Genome
Title: Mart1 is located on mouse chromosome 19 and is excluded as a candidate for ep and ru.
Volume: 8
Issue: 5
Pages: 377-8
Publication      
First Author: Raymundo JR
Year: 2023
Journal: J Clin Invest
Title: KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions and their impairment causes aplasia cutis.
Publication
First Author: Raviv S
Year: 2014
Journal: PLoS Genet
Title: PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF.
Volume: 10
Issue: 5
Pages: e1004360
Publication      
First Author: Sahut-Barnola I
Year: 2022
Journal: J Invest Dermatol
Title: Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome.
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: melan-A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: transgene insertion 5, Friedrich Beermann
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: melan-A; targeted mutation 1.2, Friedrich Beermann
Allele Type: Targeted
Attribute String: Null/knockout