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Search results 1 to 100 out of 544 for Mlh1

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
4292 | MLH1
Type: gene
Organism: human
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Gene
533652 | MLH1
Type: gene
Organism: cattle
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Gene
420729 | MLH1
Type: gene
Organism: chicken
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Gene
393632 | mlh1
Type: gene
Organism: zebrafish
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Gene
698782 | MLH1
Type: gene
Organism: macaque, rhesus
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Gene
100170640 | mlh1
Type: gene
Organism: frog, western clawed
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Gene
81685 | Mlh1
Type: gene
Organism: rat
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Gene
477019 | MLH1
Type: gene
Organism: dog, domestic
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Gene
747104 | MLH1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:101938 | Mlh1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
10096563 | J:53451
First Author: Edelmann W
Year: 1999
Journal: Cancer Res
Title: Tumorigenesis in Mlh1 and Mlh1/Apc1638N mutant mice.
Volume: 59
Issue: 6
Pages: 1301-7
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Publication
15480418 | J:94712
First Author: Shao C
Year: 2004
Journal: Oncogene
Title: Mlh1 mediates tissue-specific regulation of mitotic recombination.
Volume: 23
Issue: 56
Pages: 9017-24
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Publication
10851078 | J:62824
First Author: Shoemaker AR
Year: 2000
Journal: Oncogene
Title: Mlh1 deficiency enhances several phenotypes of Apc(Min)/+ mice.
Volume: 19
Issue: 23
Pages: 2774-9
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Publication
8674118 | J:33878
First Author: Edelmann W
Year: 1996
Journal: Cell
Title: Meiotic pachytene arrest in MLH1-deficient mice.
Volume: 85
Issue: 7
Pages: 1125-34
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GXD Expression
GXD Expression
 
Probe: MGI:5800470
Assay Type: Immunohistochemistry
Annotation Date: 2016-10-13
Strength: Weak
Sex: Male
Emaps: EMAPS:3148428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5800536
Age: postnatal
Note: Pachytene spermatocytes are deficient in Mlh1 foci.
Specimen Label: 6A M1ap
Detected: true
Specimen Num: 2
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Publication
12881715 | J:84658
First Author: Gutmann DH
Year: 2003
Journal: Oncogene
Title: Mlh1 deficiency accelerates myeloid leukemogenesis in neurofibromatosis 1 (Nf1) heterozygous mice.
Volume: 22
Issue: 29
Pages: 4581-5
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Publication
11555625 | J:71822
First Author: Ellison AR
Year: 2001
Journal: Hum Mol Genet
Title: Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae.
Volume: 10
Issue: 18
Pages: 1889-900
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Publication
29701748 | J:262594
First Author: Pussila M
Year: 2018
Journal: Carcinogenesis
Title: Mlh1 deficiency in normal mouse colon mucosa associates with chromosomally unstable colon cancer.
Volume: 39
Issue: 6
Pages: 788-797
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Publication
30275527 | J:274254
First Author: Patel R
Year: 2019
Journal: Leukemia
Title: Mlh1 deficiency increases the risk of hematopoietic malignancy after simulated space radiation exposure.
Volume: 33
Issue: 5
Pages: 1135-1147
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Publication
19690386 | J:152704
First Author: Fu Z
Year: 2009
Journal: J Clin Invest
Title: Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.
Volume: 119
Issue: 9
Pages: 2714-24
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Publication
13679151 | J:85814
First Author: Takagi Y
Year: 2003
Journal: DNA Repair (Amst)
Title: Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis.
Volume: 2
Issue: 10
Pages: 1135-46
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Publication
12743174 | J:83489
First Author: Schrader CE
Year: 2003
Journal: J Exp Med
Title: Mlh1 can function in antibody class switch recombination independently of Msh2.
Volume: 197
Issue: 10
Pages: 1377-83
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Publication
10092760 | J:53460
First Author: Phung QH
Year: 1999
Journal: J Immunol
Title: Hypermutation in Ig V genes from mice deficient in the MLH1 mismatch repair protein.
Volume: 162
Issue: 6
Pages: 3121-4
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Publication
10385520 | J:56169
First Author: Woods LM
Year: 1999
Journal: J Cell Biol
Title: Chromosomal influence on meiotic spindle assembly: abnormal meiosis I in female Mlh1 mutant mice.
Volume: 145
Issue: 7
Pages: 1395-406
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Publication
19755659 | J:154792
First Author: Itano O
Year: 2009
Journal: Carcinogenesis
Title: Sulindac effects on inflammation and tumorigenesis in the intestine of mice with Apc and Mlh1 mutations.
Volume: 30
Issue: 11
Pages: 1923-6
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Publication
19934329 | J:155534
First Author: van de Vrugt HJ
Year: 2009
Journal: Cancer Res
Title: Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.
Volume: 69
Issue: 24
Pages: 9431-8
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Publication
11126362 | J:67119
First Author: Kuraguchi M
Year: 2000
Journal: Oncogene
Title: Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency.
Volume: 19
Issue: 50
Pages: 5755-63
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Publication
22451719 | J:183862
First Author: Chahwan R
Year: 2012
Journal: J Exp Med
Title: The ATPase activity of MLH1 is required to orchestrate DNA double-strand breaks and end processing during class switch recombination.
Volume: 209
Issue: 4
Pages: 671-8
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Publication
34469738 | J:324645
First Author: Goold R
Year: 2021
Journal: Cell Rep
Title: FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Volume: 36
Issue: 9
Pages: 109649
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Publication
24204323 | J:205134
First Author: Pinto RM
Year: 2013
Journal: PLoS Genet
Title: Mismatch repair genes Mlh1 and Mlh3 modify CAG instability in Huntington's disease mice: genome-wide and candidate approaches.
Volume: 9
Issue: 10
Pages: e1003930
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Publication
8673133 | J:34291
First Author: Baker SM
Year: 1996
Journal: Nat Genet
Title: Involvement of mouse Mlh1 in DNA mismatch repair and meiotic crossing over.
Volume: 13
Issue: 3
Pages: 336-42
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Publication
32876667 | J:298297
First Author: Loupe JM
Year: 2020
Journal: Hum Mol Genet
Title: Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Volume: 29
Issue: 18
Pages: 3044-3053
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QTL
MGI:6400568 | Mlh1fc1
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6400569 | Mlh1fc2
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6400571 | Mlh1fc4
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6400570 | Mlh1fc3
Type: QTL
Organism: mouse, laboratory
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Publication
10657972 | J:60616
First Author: Kawate H
Year: 2000
Journal: Carcinogenesis
Title: A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice.
Volume: 21
Issue: 2
Pages: 301-5
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Publication
- | J:265207
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for andalusia2.
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Publication
- | J:265206
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for andalusia.
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Publication
30949703 | J:285969
First Author: Liu H
Year: 2019
Journal: Nucleic Acids Res
Title: SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice.
Volume: 47
Issue: 11
Pages: 5670-5683
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Publication
8145827 | J:17196
First Author: Bronner CE
Year: 1994
Journal: Nature
Title: Mutation in the DNA mismatch repair gene homologue hMLH1 is associated with hereditary non-polyposis colon cancer.
Volume: 368
Issue: 6468
Pages: 258-61
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Publication
14716311 | J:87869
First Author: Bardwell PD
Year: 2004
Journal: Nat Immunol
Title: Altered somatic hypermutation and reduced class-switch recombination in exonuclease 1-mutant mice.
Volume: 5
Issue: 2
Pages: 224-9
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Publication
34408140 | J:324056
First Author: Singh P
Year: 2021
Journal: Nat Commun
Title: Human MLH1/3 variants causing aneuploidy, pregnancy loss, and premature reproductive aging.
Volume: 12
Issue: 1
Pages: 5005
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Publication
19196996 | J:146488
First Author: Bolitho P
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Perforin-mediated suppression of B-cell lymphoma.
Volume: 106
Issue: 8
Pages: 2723-8
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Publication
15700306 | J:98929
First Author: Kabbarah O
Year: 2005
Journal: Int J Cancer
Title: Diethylstilbestrol effects and lymphomagenesis in Mlh1-deficient mice.
Volume: 115
Issue: 4
Pages: 666-9
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Publication
18337503 | J:133352
First Author: Avdievich E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.
Volume: 105
Issue: 11
Pages: 4247-52
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Publication
24204690 | J:209185
First Author: Pussila M
Year: 2013
Journal: PLoS One
Title: Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice.
Volume: 8
Issue: 10
Pages: e76865
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Publication
21497085 | J:172059
First Author: Nagaoka SI
Year: 2011
Journal: Curr Biol
Title: Oocyte-specific differences in cell-cycle control create an innate susceptibility to meiotic errors.
Volume: 21
Issue: 8
Pages: 651-7
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Publication
17347588 | J:122701
First Author: Taniguchi K
Year: 2006
Journal: Oncology
Title: Mild inflammation accelerates colon carcinogenesis in Mlh1-deficient mice.
Volume: 71
Issue: 1-2
Pages: 124-30
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Publication
30721949 | J:274223
First Author: Daino K
Year: 2019
Journal: Carcinogenesis
Title: Mutational landscape of T-cell lymphoma in mice lacking the DNA mismatch repair gene Mlh1: no synergism with ionizing radiation.
Volume: 40
Issue: 2
Pages: 216-224
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Publication
15084308 | J:89325
First Author: Bannister LA
Year: 2004
Journal: DNA Repair (Amst)
Title: Modulation of error-prone double-strand break repair in mammalian chromosomes by DNA mismatch repair protein Mlh1.
Volume: 3
Issue: 5
Pages: 465-74
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Publication
12419828 | J:80008
First Author: Tsao JL
Year: 2002
Journal: Carcinogenesis
Title: Diet, cancer and aging in DNA mismatch repair deficient mice.
Volume: 23
Issue: 11
Pages: 1807-10
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Publication
25529563 | J:316601
First Author: Morioka T
Year: 2015
Journal: Cancer Sci
Title: Ionizing radiation, inflammation, and their interactions in colon carcinogenesis in Mlh1-deficient mice.
Volume: 106
Issue: 3
Pages: 217-26
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Publication
19638594 | J:151771
First Author: Edwards RA
Year: 2009
Journal: Cancer Res
Title: Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Volume: 69
Issue: 16
Pages: 6423-9
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Publication
17086208 | J:121058
First Author: Kakinuma S
Year: 2007
Journal: Oncogene
Title: Ikaros is a mutational target for lymphomagenesis in Mlh1-deficient mice.
Volume: 26
Issue: 20
Pages: 2945-9
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Publication
16672050 | J:115062
 
First Author: Reed KR
Year: 2006
Journal: BMC Cancer
Title: PPARdelta status and mismatch repair mediated neoplasia in the mouse intestine.
Volume: 6
Pages: 113
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Publication
14562041 | J:86055
First Author: Sansom OJ
Year: 2003
Journal: Oncogene
Title: MBD4 deficiency reduces the apoptotic response to DNA-damaging agents in the murine small intestine.
Volume: 22
Issue: 46
Pages: 7130-6
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Publication
16256150 | J:106384
First Author: Smith-Roe SL
Year: 2006
Journal: Mutat Res
Title: Mlh1-dependent suppression of specific mutations induced in vivo by the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP).
Volume: 594
Issue: 1-2
Pages: 101-12
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Publication
12217320 | J:78790
First Author: Eaker S
Year: 2002
Journal: Dev Biol
Title: Meiotic prophase abnormalities and metaphase cell death in MLH1-deficient mouse spermatocytes: insights into regulation of spermatogenic progress.
Volume: 249
Issue: 1
Pages: 85-95
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Publication
16204034 | J:102704
First Author: Chen PC
Year: 2005
Journal: Cancer Res
Title: Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.
Volume: 65
Issue: 19
Pages: 8662-70
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Publication
19553545 | J:151397
First Author: Eccleston J
Year: 2009
Journal: J Immunol
Title: Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats.
Volume: 183
Issue: 2
Pages: 1222-8
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Publication
10359802 | J:55724
First Author: Yao X
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Different mutator phenotypes in Mlh1- versus Pms2-deficient mice.
Volume: 96
Issue: 12
Pages: 6850-5
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Publication
11940649 | J:75745
First Author: Trinh BN
Year: 2002
Journal: Mol Cell Biol
Title: DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair.
Volume: 22
Issue: 9
Pages: 2906-17
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Publication
11313994 | J:68922
First Author: Baross-Francis A
Year: 2001
Journal: Oncogene
Title: Elevated mutant frequencies and increased C : G-->T : A transitions in Mlh1-/- versus Pms2-/- murine small intestinal epithelial cells.
Volume: 20
Issue: 5
Pages: 619-25
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Publication
18057311 | J:135274
First Author: Kan R
Year: 2008
Journal: Biol Reprod
Title: Comparative analysis of meiotic progression in female mice bearing mutations in genes of the DNA mismatch repair pathway.
Volume: 78
Issue: 3
Pages: 462-71
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Publication
16150740 | J:101745
First Author: Ziv S
Year: 2005
Journal: Hum Mol Genet
Title: Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia.
Volume: 14
Issue: 19
Pages: 2929-43
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Publication
26753533 | J:324085
 
First Author: Fischer JM
Year: 2016
Journal: DNA Repair (Amst)
Title: An intact Pms2 ATPase domain is not essential for male fertility.
Volume: 39
Pages: 46-51
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Publication
21242524 | J:169152
First Author: Eccleston J
Year: 2011
Journal: J Immunol
Title: Mismatch repair proteins MSH2, MLH1, and EXO1 are important for class-switch recombination events occurring in B cells that lack nonhomologous end joining.
Volume: 186
Issue: 4
Pages: 2336-43
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Publication
11828012 | J:124827
First Author: Schrader CE
Year: 2002
Journal: J Exp Med
Title: Role for mismatch repair proteins Msh2, Mlh1, and Pms2 in immunoglobulin class switching shown by sequence analysis of recombination junctions.
Volume: 195
Issue: 3
Pages: 367-73
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Publication
12967659 | J:85600
First Author: Sansom OJ
Year: 2003
Journal: DNA Repair (Amst)
Title: Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo.
Volume: 2
Issue: 9
Pages: 1029-39
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Publication
10430621 | J:56764
First Author: Schrader CE
Year: 1999
Journal: J Exp Med
Title: Reduced isotype switching in splenic B cells from mice deficient in mismatch repair enzymes.
Volume: 190
Issue: 3
Pages: 323-30
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Publication
17344431 | J:120812
First Author: Moens PB
Year: 2007
Journal: J Cell Sci
Title: Initiation and resolution of interhomolog connections: crossover and non-crossover sites along mouse synaptonemal complexes.
Volume: 120
Issue: Pt 6
Pages: 1017-27
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Publication
17291760 | J:120745
First Author: Cherry SM
Year: 2007
Journal: Curr Biol
Title: The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis.
Volume: 17
Issue: 4
Pages: 373-8
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Publication
32232159 | J:289957
First Author: Guan Y
Year: 2020
Journal: Sci Adv
Title: SKP1 drives the prophase I to metaphase I transition during male meiosis.
Volume: 6
Issue: 13
Pages: eaaz2129
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Publication
21637789 | J:172714
First Author: Schramm S
Year: 2011
Journal: PLoS Genet
Title: A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility.
Volume: 7
Issue: 5
Pages: e1002088
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Publication
31256246 | J:281207
First Author: Vazquez BN
Year: 2019
Journal: Chromosoma
Title: SIRT7 promotes chromosome synapsis during prophase I of female meiosis.
Volume: 128
Issue: 3
Pages: 369-383
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Publication
12091911 | J:78200
First Author: Lipkin SM
Year: 2002
Journal: Nat Genet
Title: Meiotic arrest and aneuploidy in MLH3-deficient mice.
Volume: 31
Issue: 4
Pages: 385-90
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Publication
24966277 | J:213861
First Author: Peng M
Year: 2014
Journal: EMBO J
Title: Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.
Volume: 33
Issue: 15
Pages: 1698-712
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Publication
- | J:98660
First Author: Ellenson LH
Year: 2005
Journal: Int J Gynecol Cancer
Title: Early molecular changes in endometrial cancer.
Volume: 15
Issue: 2
Pages: 399-400 (Abstr.)
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Publication
12913077 | J:85108
First Author: Wong JC
Year: 2003
Journal: Hum Mol Genet
Title: Targeted disruption of exons 1 to 6 of the Fanconi Anemia group A gene leads to growth retardation, strain-specific microphthalmia, meiotic defects and primordial germ cell hypoplasia.
Volume: 12
Issue: 16
Pages: 2063-76
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Publication
16260499 | J:104493
First Author: Kolas NK
Year: 2005
Journal: J Cell Biol
Title: Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.
Volume: 171
Issue: 3
Pages: 447-58
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QTL
MGI:6400573 | Sccor2
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6400572 | Sccor1
Type: QTL
Organism: mouse, laboratory
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QTL
MGI:6400574 | Sccor3
Type: QTL
Organism: mouse, laboratory
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Publication
17696610 | J:123677
First Author: Li XC
Year: 2007
Journal: PLoS Genet
Title: Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis.
Volume: 3
Issue: 8
Pages: e130
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Protein Coding Gene
MGP_CAROLIEiJ_G0032755 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035283 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035347 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_101938 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035022 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035260 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035168 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035889 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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