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Search results 1 to 100 out of 210 for Mlkl

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0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication  
First Author: Zhang J
Year: 2019
Journal: Mol Immunol
Title: MLKL deficiency inhibits DSS-induced colitis independent of intestinal microbiota.
Volume: 107
Pages: 132-141
Publication
First Author: Wu J
Year: 2013
Journal: Cell Res
Title: Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.
Volume: 23
Issue: 8
Pages: 994-1006
Publication  
First Author: Xu H
Year: 2019
Journal: Mol Metab
Title: The pseudokinase MLKL regulates hepatic insulin sensitivity independently of inflammation.
Volume: 23
Pages: 14-23
Publication
First Author: Amini P
Year: 2016
Journal: Eur J Immunol
Title: NET formation can occur independently of RIPK3 and MLKL signaling.
Volume: 46
Issue: 1
Pages: 178-84
Publication
First Author: Murphy JM
Year: 2013
Journal: Immunity
Title: The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism.
Volume: 39
Issue: 3
Pages: 443-53
Publication  
First Author: D'Cruz AA
Year: 2018
Journal: Sci Signal
Title: The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils.
Volume: 11
Issue: 546
Publication  
First Author: Zhao Q
Year: 2019
Journal: Cancer Lett
Title: MLKL attenuates colon inflammation and colitis-tumorigenesis via suppression of inflammatory responses.
Volume: 459
Pages: 100-111
Publication
First Author: Xiong Y
Year: 2019
Journal: Cell Death Differ
Title: The bromodomain protein BRD4 positively regulates necroptosis via modulating MLKL expression.
Volume: 26
Issue: 10
Pages: 1929-1941
Publication
First Author: Ying Z
Year: 2018
Journal: Mol Cell
Title: Mixed Lineage Kinase Domain-like Protein MLKL Breaks Down Myelin following Nerve Injury.
Volume: 72
Issue: 3
Pages: 457-468.e5
Publication
First Author: Conos SA
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner.
Volume: 114
Issue: 6
Pages: E961-E969
Publication  
First Author: Kang S
Year: 2015
Journal: Nat Commun
Title: Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.
Volume: 6
Pages: 7515
Publication
First Author: Cai Z
Year: 2014
Journal: Nat Cell Biol
Title: Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis.
Volume: 16
Issue: 1
Pages: 55-65
Publication
First Author: Wang H
Year: 2014
Journal: Mol Cell
Title: Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3.
Volume: 54
Issue: 1
Pages: 133-146
Publication
First Author: Sai K
Year: 2019
Journal: J Cell Biol
Title: Necroptosis mediators RIPK3 and MLKL suppress intracellular Listeria replication independently of host cell killing.
Volume: 218
Issue: 6
Pages: 1994-2005
Publication
First Author: Zhang X
Year: 2016
Journal: Cell Rep
Title: MLKL and FADD Are Critical for Suppressing Progressive Lymphoproliferative Disease and Activating the NLRP3 Inflammasome.
Volume: 16
Issue: 12
Pages: 3247-3259
Publication
First Author: Hildebrand JM
Year: 2020
Journal: Nat Commun
Title: A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction.
Volume: 11
Issue: 1
Pages: 3150
Publication  
First Author: Moerke C
Year: 2019
Journal: Front Cell Dev Biol
Title: Combined Knockout of RIPK3 and MLKL Reveals Unexpected Outcome in Tissue Injury and Inflammation.
Volume: 7
Pages: 19
Publication
First Author: Tanzer MC
Year: 2015
Journal: Biochem J
Title: Necroptosis signalling is tuned by phosphorylation of MLKL residues outside the pseudokinase domain activation loop.
Volume: 471
Issue: 2
Pages: 255-65
Publication
First Author: Rodriguez DA
Year: 2016
Journal: Cell Death Differ
Title: Characterization of RIPK3-mediated phosphorylation of the activation loop of MLKL during necroptosis.
Volume: 23
Issue: 1
Pages: 76-88
Publication
First Author: Günther C
Year: 2016
Journal: J Clin Invest
Title: The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis.
Volume: 126
Issue: 11
Pages: 4346-4360
Publication
First Author: Sarhan J
Year: 2019
Journal: Cell Death Differ
Title: Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.
Volume: 26
Issue: 2
Pages: 332-347
Publication
First Author: Alvarez-Diaz S
Year: 2016
Journal: Immunity
Title: The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis.
Volume: 45
Issue: 3
Pages: 513-526
Publication
First Author: Hildebrand JM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death.
Volume: 111
Issue: 42
Pages: 15072-7
Publication
First Author: Newton K
Year: 2016
Journal: Cell Death Differ
Title: RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury.
Volume: 23
Issue: 9
Pages: 1565-76
Publication
First Author: Van Hoecke L
Year: 2018
Journal: Nat Commun
Title: Treatment with mRNA coding for the necroptosis mediator MLKL induces antitumor immunity directed against neo-epitopes.
Volume: 9
Issue: 1
Pages: 3417
Publication      
First Author: Wang Y
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Ghoulish.
Publication  
First Author: Riegler AN
Year: 2019
Journal: Front Immunol
Title: Necroptotic Cell Death Promotes Adaptive Immunity Against Colonizing Pneumococci.
Volume: 10
Pages: 615
Publication
First Author: Tanzer MC
Year: 2016
Journal: Cell Death Differ
Title: Evolutionary divergence of the necroptosis effector MLKL.
Volume: 23
Issue: 7
Pages: 1185-97
Publication
First Author: Sun L
Year: 2012
Journal: Cell
Title: Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.
Volume: 148
Issue: 1-2
Pages: 213-27
Publication
First Author: Xie T
Year: 2013
Journal: Cell Rep
Title: Structural insights into RIP3-mediated necroptotic signaling.
Volume: 5
Issue: 1
Pages: 70-8
Publication
First Author: Zhang T
Year: 2020
Journal: Cell
Title: Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis.
Volume: 180
Issue: 6
Pages: 1115-1129.e13
Publication
First Author: Desai J
Year: 2016
Journal: Eur J Immunol
Title: PMA and crystal-induced neutrophil extracellular trap formation involves RIPK1-RIPK3-MLKL signaling.
Volume: 46
Issue: 1
Pages: 223-9
Publication
First Author: Nogusa S
Year: 2016
Journal: Cell Host Microbe
Title: RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.
Volume: 20
Issue: 1
Pages: 13-24
Publication    
First Author: Li D
Year: 2017
Journal: Elife
Title: RIPK1-RIPK3-MLKL-dependent necrosis promotes the aging of mouse male reproductive system.
Volume: 6
Publication
First Author: Yang J
Year: 2018
Journal: Cereb Cortex
Title: RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex.
Volume: 28
Issue: 7
Pages: 2622-2635
Publication
First Author: Wang X
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense.
Volume: 111
Issue: 43
Pages: 15438-43
Publication
First Author: González-Juarbe N
Year: 2017
Journal: Cell Death Differ
Title: Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia.
Volume: 24
Issue: 5
Pages: 917-928
Publication
First Author: Xu C
Year: 2018
Journal: J Immunol
Title: Embryonic Lethality and Host Immunity of RelA-Deficient Mice Are Mediated by Both Apoptosis and Necroptosis.
Volume: 200
Issue: 1
Pages: 271-285
Publication  
First Author: Mulay SR
Year: 2016
Journal: Nat Commun
Title: Cytotoxicity of crystals involves RIPK3-MLKL-mediated necroptosis.
Volume: 7
Pages: 10274
Publication
First Author: Zhao J
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Mixed lineage kinase domain-like is a key receptor interacting protein 3 downstream component of TNF-induced necrosis.
Volume: 109
Issue: 14
Pages: 5322-7
Publication
First Author: Speir M
Year: 2020
Journal: Nat Immunol
Title: Ptpn6 inhibits caspase-8- and Ripk3/Mlkl-dependent inflammation.
Volume: 21
Issue: 1
Pages: 54-64
Publication
First Author: Daniels BP
Year: 2017
Journal: Cell
Title: RIPK3 Restricts Viral Pathogenesis via Cell Death-Independent Neuroinflammation.
Volume: 169
Issue: 2
Pages: 301-313.e11
Publication
First Author: Yoon S
Year: 2017
Journal: Immunity
Title: MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation.
Volume: 47
Issue: 1
Pages: 51-65.e7
Publication  
First Author: Devos M
Year: 2020
Journal: J Exp Med
Title: Sensing of endogenous nucleic acids by ZBP1 induces keratinocyte necroptosis and skin inflammation.
Volume: 217
Issue: 7
Publication
First Author: Webster JD
Year: 2020
Journal: J Leukoc Biol
Title: RIP1 kinase activity is critical for skin inflammation but not for viral propagation.
Volume: 107
Issue: 6
Pages: 941-952
Publication
First Author: Zhang Y
Year: 2020
Journal: Cell Death Dis
Title: Catalytically inactive RIP1 and RIP3 deficiency protect against acute ischemic stroke by inhibiting necroptosis and neuroinflammation.
Volume: 11
Issue: 7
Pages: 565
Publication
First Author: Ni HM
Year: 2019
Journal: Am J Pathol
Title: Receptor-Interacting Serine/Threonine-Protein Kinase 3 (RIPK3)-Mixed Lineage Kinase Domain-Like Protein (MLKL)-Mediated Necroptosis Contributes to Ischemia-Reperfusion Injury of Steatotic Livers.
Volume: 189
Issue: 7
Pages: 1363-1374
Publication
First Author: Zhang S
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: RIP1 kinase inhibitor halts the progression of an immune-induced demyelination disease at the stage of monocyte elevation.
Volume: 116
Issue: 12
Pages: 5675-5680
Publication
First Author: Lin QS
Year: 2020
Journal: Lab Invest
Title: RIP1/RIP3/MLKL mediates dopaminergic neuron necroptosis in a mouse model of Parkinson disease.
Volume: 100
Issue: 3
Pages: 503-511
Publication  
First Author: Kim TY
Year: 2021
Journal: Biochem Biophys Res Commun
Title: Down-regulation of pro-necroptotic molecules blunts necroptosis during myogenesis.
Volume: 557
Pages: 33-39
Publication
First Author: O'Donnell JA
Year: 2018
Journal: J Immunol
Title: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.
Volume: 200
Issue: 2
Pages: 737-748
Publication
First Author: Zhang J
Year: 2019
Journal: Cell Rep
Title: Ubiquitin Ligases cIAP1 and cIAP2 Limit Cell Death to Prevent Inflammation.
Volume: 27
Issue: 9
Pages: 2679-2689.e3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication      
First Author: Wang Y
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for secro
Publication      
First Author: Wang Y
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for necro
Publication      
First Author: Wang Y
Year: 2016
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for mecro
Publication
First Author: Desai J
Year: 2017
Journal: Sci Rep
Title: Particles of different sizes and shapes induce neutrophil necroptosis followed by the release of neutrophil extracellular trap-like chromatin.
Volume: 7
Issue: 1
Pages: 15003
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:6196374
Assay Type: Western blot
Annotation Date: 2018-09-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6196560
Age: embryonic day 10.5
Detected: false
Specimen Num: 8
Publication
First Author: Lin J
Year: 2016
Journal: Nature
Title: RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.
Volume: 540
Issue: 7631
Pages: 124-128
Publication
First Author: Chen W
Year: 2013
Journal: J Biol Chem
Title: Diverse sequence determinants control human and mouse receptor interacting protein 3 (RIP3) and mixed lineage kinase domain-like (MLKL) interaction in necroptotic signaling.
Volume: 288
Issue: 23
Pages: 16247-61
Publication  
First Author: Lawlor KE
Year: 2015
Journal: Nat Commun
Title: RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Volume: 6
Pages: 6282
Publication
First Author: Someda M
Year: 2020
Journal: Cell Death Differ
Title: Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
Volume: 27
Issue: 5
Pages: 1539-1553
Publication
First Author: Newton K
Year: 2016
Journal: Nature
Title: RIPK1 inhibits ZBP1-driven necroptosis during development.
Volume: 540
Issue: 7631
Pages: 129-133
Publication
First Author: Newton K
Year: 2019
Journal: Nature
Title: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Volume: 574
Issue: 7778
Pages: 428-431
Publication
First Author: Peltzer N
Year: 2018
Journal: Nature
Title: LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.
Volume: 557
Issue: 7703
Pages: 112-117
Publication
First Author: Bisson N
Year: 2008
Journal: Cell Cycle
Title: Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild type phenotype.
Volume: 7
Issue: 7
Pages: 909-16
Publication
First Author: Liu Z
Year: 2021
Journal: Immunity
Title: A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation.
Volume: 54
Issue: 2
Pages: 247-258.e7
Publication
First Author: Yu X
Year: 2015
Journal: J Virol
Title: Herpes Simplex Virus 1 (HSV-1) and HSV-2 Mediate Species-Specific Modulations of Programmed Necrosis through the Viral Ribonucleotide Reductase Large Subunit R1.
Volume: 90
Issue: 2
Pages: 1088-95
Publication
First Author: Guo H
Year: 2018
Journal: Cell Death Dis
Title: Species-independent contribution of ZBP1/DAI/DLM-1-triggered necroptosis in host defense against HSV1.
Volume: 9
Issue: 8
Pages: 816
Publication  
First Author: Imamura M
Year: 2018
Journal: JCI Insight
Title: RIPK3 promotes kidney fibrosis via AKT-dependent ATP citrate lyase.
Volume: 3
Issue: 3
Publication
First Author: Kitur K
Year: 2016
Journal: Cell Rep
Title: Necroptosis Promotes Staphylococcus aureus Clearance by Inhibiting Excessive Inflammatory Signaling.
Volume: 16
Issue: 8
Pages: 2219-2230
Publication
First Author: Tisch N
Year: 2019
Journal: J Clin Invest
Title: Caspase-8 modulates physiological and pathological angiogenesis during retina development.
Volume: 129
Issue: 12
Pages: 5092-5107
Publication
First Author: Strilic B
Year: 2016
Journal: Nature
Title: Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis.
Volume: 536
Issue: 7615
Pages: 215-8