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Search results 1 to 100 out of 841 for Mlx

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0.041s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Protein Domain
Type: Family
Description: Mlx is a Max-like basic-helix-loop-helix zipper protein that interacts with the Max network of transcription factors [, , ]. Mlx forms a complex with MondoA (also known as MLXIP), and this complex regulates glucose-induced gene expression []. The transcriptional activity of the MondoA-Mlx complex is limited by mTOR-MondoA interaction [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Carroll PA
Year: 2021
Journal: PLoS Biol
Title: The glucose-sensing transcription factor MLX balances metabolism and stress to suppress apoptosis and maintain spermatogenesis.
Volume: 19
Issue: 10
Pages: e3001085
Publication
First Author: Diolaiti D
Year: 2015
Journal: Biochim Biophys Acta
Title: Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis.
Volume: 1849
Issue: 5
Pages: 484-500
Publication  
First Author: Billin AN
Year: 2006
Journal: Curr Top Microbiol Immunol
Title: The Mlx network: evidence for a parallel Max-like transcriptional network that regulates energy metabolism.
Volume: 302
Pages: 255-78
Publication
First Author: Wang H
Year: 2022
Journal: Cell Mol Gastroenterol Hepatol
Title: Coordinated Cross-Talk Between the Myc and Mlx Networks in Liver Regeneration and Neoplasia.
Volume: 13
Issue: 6
Pages: 1785-1804
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Stoeckman AK
Year: 2004
Journal: J Biol Chem
Title: Mlx is the functional heteromeric partner of the carbohydrate response element-binding protein in glucose regulation of lipogenic enzyme genes.
Volume: 279
Issue: 15
Pages: 15662-9
Publication
First Author: Hunt LC
Year: 2015
Journal: Genes Dev
Title: The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.
Volume: 29
Issue: 23
Pages: 2475-89
Gene
Type: gene
Organism: human
Publication
First Author: Billin AN
Year: 1999
Journal: J Biol Chem
Title: Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors.
Volume: 274
Issue: 51
Pages: 36344-50
Publication
First Author: Kaadige MR
Year: 2015
Journal: Mol Cell Biol
Title: MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction.
Volume: 35
Issue: 1
Pages: 101-10
Publication
First Author: Sans CL
Year: 2006
Journal: Mol Cell Biol
Title: MondoA-Mlx heterodimers are candidate sensors of cellular energy status: mitochondrial localization and direct regulation of glycolysis.
Volume: 26
Issue: 13
Pages: 4863-71
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190802
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mlx
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190802
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mlx
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190802
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mlx
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190802
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mlx
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190802
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mlx
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190802
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mlx
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6178033
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190802
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mlx
Detected: true
Specimen Num: 7
Protein
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 298  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 244  
Fragment?: false
Publication
First Author: Peterson CW
Year: 2010
Journal: Mol Cell Biol
Title: Glucose controls nuclear accumulation, promoter binding, and transcriptional activity of the MondoA-Mlx heterodimer.
Volume: 30
Issue: 12
Pages: 2887-95
Publication
First Author: Herman MA
Year: 2012
Journal: Nature
Title: A novel ChREBP isoform in adipose tissue regulates systemic glucose metabolism.
Volume: 484
Issue: 7394
Pages: 333-8
Publication
First Author: Bricambert J
Year: 2010
Journal: J Clin Invest
Title: Salt-inducible kinase 2 links transcriptional coactivator p300 phosphorylation to the prevention of ChREBP-dependent hepatic steatosis in mice.
Volume: 120
Issue: 12
Pages: 4316-31
Publication
First Author: Eilers AL
Year: 2002
Journal: Mol Cell Biol
Title: A novel heterodimerization domain, CRM1, and 14-3-3 control subcellular localization of the MondoA-Mlx heterocomplex.
Volume: 22
Issue: 24
Pages: 8514-26
Publication
First Author: Cairo S
Year: 2001
Journal: Hum Mol Genet
Title: WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network.
Volume: 10
Issue: 6
Pages: 617-27
Publication
First Author: Sakiyama H
Year: 2008
Journal: J Biol Chem
Title: Regulation of nuclear import/export of carbohydrate response element-binding protein (ChREBP): interaction of an alpha-helix of ChREBP with the 14-3-3 proteins and regulation by phosphorylation.
Volume: 283
Issue: 36
Pages: 24899-908
Publication
First Author: Meroni G
Year: 2000
Journal: Oncogene
Title: Mlx, a new Max-like bHLHZip family member: the center stage of a novel transcription factors regulatory pathway?
Volume: 19
Issue: 29
Pages: 3266-77
Publication  
First Author: Wang H
Year: 2022
Journal: Cells
Title: Disruption of Multiple Overlapping Functions Following Stepwise Inactivation of the Extended Myc Network.
Volume: 11
Issue: 24
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Bjerknes M
Year: 1996
Journal: Gene
Title: TCFL4: a gene at 17q21.1 encoding a putative basic helix-loop-helix leucine-zipper transcription factor.
Volume: 181
Issue: 1-2
Pages: 7-11
Publication      
First Author: Eisenman RN
Year: 2017
Journal: MGI Direct Data Submission
Title: Direct data submission 2017-08-30
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816704
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816704
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816704
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816704
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816704
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816704
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816704
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3815900
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816704
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3516422
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716122
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691621
Stage: TS21
Assay Id: MGI:3508072
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691627
Stage: TS27
Assay Id: MGI:3508072
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1691622
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1760622
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623037
Specimen Label: JAX_1623037
Detected: true
Specimen Num: 41
GXD Expression  
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1777821
Stage: TS21
Assay Id: MGI:3508072
Age: embryonic day 13.5
Image: 1
Note: The tissue was olfactory epithelium and/or bulb.
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1777828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623010
Specimen Label: JAX_1623010
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737322
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623026
Note: kidney
Specimen Label: JAX_1623026
Detected: true
Specimen Num: 30
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3284222
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666522
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1666528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623032
Specimen Label: JAX_1623032
Detected: true
Specimen Num: 36
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1619822
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1619828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623046
Specimen Label: JAX_1623046
Detected: true
Specimen Num: 50
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:3267828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623036
Specimen Label: JAX_1623036
Detected: true
Specimen Num: 40
GXD Expression    
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754921
Stage: TS21
Assay Id: MGI:3508072
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754927
Stage: TS27
Assay Id: MGI:3508072
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1754922
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Note: Expression was not detected in the corpus striatum (lateral ganglionic eminence).
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1754928
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623009
Specimen Label: JAX_1623009
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697421
Stage: TS21
Assay Id: MGI:3508072
Age: embryonic day 13.5
Image: 1
Specimen Label: 1
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:3506591
Assay Type: RNA in situ
Annotation Date: 2004-12-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697427
Stage: TS27
Assay Id: MGI:3508072
Age: postnatal newborn
Image: 2
Specimen Label: 2
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:5310427
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1697422
Stage: TS22
Assay Id: MGI:5423750
Age: embryonic day 14.5
Specimen Label: EB536; Specimen B319
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1697428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6691130
Age: postnatal adult
Image: JAX_1623005
Specimen Label: JAX_1623005
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:3506592
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Female
Emaps: EMAPS:2769723
Stage: TS23
Assay Id: MGI:5539579
Age: embryonic day 15.5
Image: GUDMAP:5924
Specimen Label: GUDMAP:5924
Detected: false
Specimen Num: 1