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Search results 1 to 77 out of 77 for Mmel1

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Hits by Category

Hits by Strain

Type Details Score
Gene
79258 | MMEL1
Type: gene
Organism: human
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Gene
100145721 | mmel1
Type: gene
Organism: frog, western clawed
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Gene
313755 | Mmel1
Type: gene
Organism: rat
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Gene
489617 | MMEL1
Type: gene
Organism: dog, domestic
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Gene
744165 | MMEL1
Type: gene
Organism: chimpanzee
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Gene
616991 | MMEL1
Type: gene
Organism: cattle
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Gene
770671 | MMEL1
Type: gene
Organism: chicken
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Gene
560703 | mmel1
Type: gene
Organism: zebrafish
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Gene
698525 | MMEL1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1351603 | Mmel1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029735 | MMEL1
Type: Family
Description: Membrane metallo-endopeptidase-like 1 (MMEL1, also known as Neprilysin 2) is a metalloprotease involved in sperm function and neuropeptide degradation [, ]. The expression of MMEL1 is limited to the testis and CNS []. In humans, it is involved in beta-amyloid (Abeta) degradation and hence associated with Alzheimer's disease [].
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Publication
11278416 | J:70325
First Author: Shirotani K
Year: 2001
Journal: J Biol Chem
Title: Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.
Volume: 276
Issue: 24
Pages: 21895-901
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Protein
B2RPX5
Organism: Mus musculus/domesticus
Length: 742  
Fragment?: false
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Gene
105378597 | MMEL1-AS1
Type: gene
Organism: human
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Publication
10814502 | -
First Author: Ouimet T
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Neprilysin II: A putative novel metalloprotease and its isoforms in CNS and testis.
Volume: 271
Issue: 3
Pages: 565-70
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Publication
18571334 | -
First Author: Huang JY
Year: 2008
Journal: Neuroscience
Title: Human membrane metallo-endopeptidase-like protein degrades both beta-amyloid 42 and beta-amyloid 40.
Volume: 155
Issue: 1
Pages: 258-62
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Protein
B1AS18
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
Q9JLI3
Organism: Mus musculus/domesticus
Length: 765  
Fragment?: false
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Protein
B1AS17
Organism: Mus musculus/domesticus
Length: 782  
Fragment?: false
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Protein
E9QPA9
Organism: Mus musculus/domesticus
Length: 780  
Fragment?: false
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Protein
E9PVK7
Organism: Mus musculus/domesticus
Length: 766  
Fragment?: false
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Protein
B1AS15
Organism: Mus musculus/domesticus
Length: 768  
Fragment?: false
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Protein
B1AS16
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0026876 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029200 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029165 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1351603 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028315 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028977 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029004 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029662 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029224 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027869 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
10542292 | J:58258
First Author: Ikeda K
Year: 1999
Journal: J Biol Chem
Title: Molecular identification and characterization of novel membrane-bound metalloprotease, the soluble secreted form of which hydrolyzes a variety of vasoactive peptides.
Volume: 274
Issue: 45
Pages: 32469-77
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Publication
10749671 | J:61898
First Author: Ghaddar G
Year: 2000
Journal: Biochem J
Title: Molecular cloning and biochemical characterization of a new mouse testis soluble-zinc-metallopeptidase of the neprilysin family.
Volume: 347
Issue: Pt 2
Pages: 419-29
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Publication
15121861 | J:89881
First Author: Carpentier M
Year: 2004
Journal: Mol Cell Biol
Title: Reduced fertility in male mice deficient in the zinc metallopeptidase NL1.
Volume: 24
Issue: 10
Pages: 4428-37
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Publication
27369050 | J:245517
First Author: Wick MJ
Year: 2016
Journal: Transgenic Res
Title: Protection against vascular leak in neprilysin transgenic mice with complex overexpression pattern.
Volume: 25
Issue: 6
Pages: 773-784
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Publication
18539150 | J:137354
First Author: Whyteside AR
Year: 2008
Journal: FEBS Lett
Title: Human neprilysin-2 (NEP2) and NEP display distinct subcellular localisations and substrate preferences.
Volume: 582
Issue: 16
Pages: 2382-6
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Publication
29191928 | J:284960
First Author: Karoor V
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice.
Volume: 38
Issue: 1
Pages: 154-163
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Publication
21224067 | J:168082
First Author: Hafez D
Year: 2011
Journal: Am J Pathol
Title: Neprilysin-2 is an important β-amyloid degrading enzyme.
Volume: 178
Issue: 1
Pages: 306-12
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Publication
25991605 | J:336965
First Author: Krohn M
Year: 2015
Journal: Brain
Title: Accumulation of murine amyloid-β mimics early Alzheimer's disease.
Volume: 138
Issue: Pt 8
Pages: 2370-82
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Mmel1<em1Smoc> | MGI:7291111
Name: membrane metallo-endopeptidase-like 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6475799 | C57BL/6JSmoc-Mmel1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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