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Search results 1 to 100 out of 772 for Mmp13

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0.036s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rabbit, European
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:5697885
Assay Type: RNA in situ
Annotation Date: 2015-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5697893
Age: embryonic day 15.0
Image: 1B Mmp13
Note: Expression is present in the middle of the hypertrophic zone.
Specimen Label: 1B Mmp13
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5447310
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5447320
Age: embryonic day 18.25
Image: 2C mmp13
Note: Expression limited to hypertrophic and terminally differentiated chondrocytes.
Specimen Label: 2C mmp13
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5447310
Assay Type: RNA in situ
Annotation Date: 2013-01-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3262826
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5447320
Age: embryonic day 18.25
Image: 2C mmp13
Note: No expression in periosteum/ perichondrium.
Specimen Label: 2C mmp13
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6830986
Assay Type: RNA in situ
Annotation Date: 2021-12-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6830999
Age: embryonic day 16.5
Image: 3D Mmp13 OsxCre;Stat3C/+
Note: Expression is in the terminal hypertrophic chondrocytes/ osteoblasts.
Specimen Label: 3D Mmp13 OsxCre;Stat3C/+
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6830986
Assay Type: RNA in situ
Annotation Date: 2021-12-08
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1910624
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6830999
Age: embryonic day 16.5
Image: 3D Mmp13 OsxCre;Stat3C/C
Specimen Label: 3D Mmp13 OsxCre;Stat3C/C
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7447508
Assay Type: RNA in situ
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7448499
Age: embryonic day 16.5
Specimen Label: 2b Mmp13 CTL
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7447508
Assay Type: RNA in situ
Annotation Date: 2023-03-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1910424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:7448499
Age: embryonic day 16.5
Note: Expression similar to that of control.
Specimen Label: 2b Mmp13 cKO
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:7356570
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7356577
Age: embryonic day 18.5
Specimen Label: S1f MMP13 WT
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7356570
Assay Type: Immunohistochemistry
Annotation Date: 2022-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1914226
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7356577
Age: embryonic day 18.5
Note: Expression unchanged compared to wild type.
Specimen Label: S1f MMP13 Mink1-/-
Detected: true
Specimen Num: 2
Publication
First Author: Lederle W
Year: 2010
Journal: Carcinogenesis
Title: MMP13 as a stromal mediator in controlling persistent angiogenesis in skin carcinoma.
Volume: 31
Issue: 7
Pages: 1175-84
Publication  
First Author: Staebler S
Year: 2023
Journal: Cells
Title: MIA/CD-RAP Regulates MMP13 and Is a Potential New Disease-Modifying Target for Osteoarthritis Therapy.
Volume: 12
Issue: 2
Publication
First Author: Wang M
Year: 2013
Journal: Arthritis Res Ther
Title: MMP13 is a critical target gene during the progression of osteoarthritis.
Volume: 15
Issue: 1
Pages: R5
Publication
First Author: Nakatani T
Year: 2017
Journal: Endocrinology
Title: MEF2C Interacts With c-FOS in PTH-Stimulated Mmp13 Gene Expression in Osteoblastic Cells.
Volume: 158
Issue: 11
Pages: 3778-3791
Publication
First Author: Elayyan J
Year: 2017
Journal: FASEB J
Title: LEF1-mediated MMP13 gene expression is repressed by SIRT1 in human chondrocytes.
Volume: 31
Issue: 7
Pages: 3116-3125
Publication
First Author: Cabrera S
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Delayed resolution of bleomycin-induced pulmonary fibrosis in absence of MMP13 (collagenase 3).
Volume: 316
Issue: 5
Pages: L961-L976
Publication
First Author: Almodóvar-García K
Year: 2014
Journal: Mol Cell Biol
Title: ANKRD1 acts as a transcriptional repressor of MMP13 via the AP-1 site.
Volume: 34
Issue: 8
Pages: 1500-11
Publication
First Author: Ponte F
Year: 2022
Journal: Sci Rep
Title: Mmp13 deletion in mesenchymal cells increases bone mass and may attenuate the cortical bone loss caused by estrogen deficiency.
Volume: 12
Issue: 1
Pages: 10257
Publication
First Author: Zhang J
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Dlx2 overexpression enhanced accumulation of type II collagen and aggrecan by inhibiting MMP13 expression in mice chondrocytes.
Volume: 503
Issue: 2
Pages: 528-535
Publication
First Author: Yu H
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: FOXO3a (Forkhead Transcription Factor O Subfamily Member 3a) Links Vascular Smooth Muscle Cell Apoptosis, Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway Involving MMP13 (Matrix Metalloproteinase 13).
Volume: 38
Issue: 3
Pages: 555-565
UniProt Feature
Begin: 111
Description: Cleavage; by MMP13
Type: site
End: 112
Publication
First Author: Quadros RM
Year: 2017
Journal: Genome Biol
Title: Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.
Volume: 18
Issue: 1
Pages: 92
Publication
First Author: Behonick DJ
Year: 2007
Journal: PLoS One
Title: Role of matrix metalloproteinase 13 in both endochondral and intramembranous ossification during skeletal regeneration.
Volume: 2
Issue: 11
Pages: e1150
Publication
First Author: Hartenstein B
Year: 2006
Journal: J Invest Dermatol
Title: Epidermal development and wound healing in matrix metalloproteinase 13-deficient mice.
Volume: 126
Issue: 2
Pages: 486-96
Publication
First Author: Fallowfield JA
Year: 2007
Journal: J Immunol
Title: Scar-associated macrophages are a major source of hepatic matrix metalloproteinase-13 and facilitate the resolution of murine hepatic fibrosis.
Volume: 178
Issue: 8
Pages: 5288-95
Publication
First Author: Vandenbroucke RE
Year: 2013
Journal: EMBO Mol Med
Title: Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF.
Volume: 5
Issue: 7
Pages: 1000-16
Publication
First Author: Nielsen BS
Year: 2008
Journal: PLoS One
Title: Matrix metalloproteinase 13 is induced in fibroblasts in polyomavirus middle T antigen-driven mammary carcinoma without influencing tumor progression.
Volume: 3
Issue: 8
Pages: e2959
Publication
First Author: Nkyimbeng T
Year: 2013
Journal: PLoS One
Title: Pivotal role of matrix metalloproteinase 13 in extracellular matrix turnover in idiopathic pulmonary fibrosis.
Volume: 8
Issue: 9
Pages: e73279
Publication
First Author: Lei H
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: Matrix metalloproteinase 13 is a new contributor to skeletal muscle regeneration and critical for myoblast migration.
Volume: 305
Issue: 5
Pages: C529-38
Publication
First Author: Pitrez PR
Year: 2020
Journal: Nat Commun
Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13.
Volume: 11
Issue: 1
Pages: 4110
Publication
First Author: Jin H
Year: 2011
Journal: FEBS Lett
Title: TGF-β signaling plays an essential role in the growth and maintenance of intervertebral disc tissue.
Volume: 585
Issue: 8
Pages: 1209-15
Publication  
First Author: Tang K
Year: 2022
Journal: Cancer Lett
Title: Elevated MMP10/13 mediated barrier disruption and NF-κB activation aggravate colitis and colon tumorigenesis in both individual or full miR-148/152 family knockout mice.
Volume: 529
Pages: 53-69
Publication
First Author: Otero M
Year: 2012
Journal: J Biol Chem
Title: E74-like factor 3 (ELF3) impacts on matrix metalloproteinase 13 (MMP13) transcriptional control in articular chondrocytes under proinflammatory stress.
Volume: 287
Issue: 5
Pages: 3559-72
Publication
First Author: Fei Y
Year: 2015
Journal: J Biol Chem
Title: Sirtuin 1 is a negative regulator of parathyroid hormone stimulation of matrix metalloproteinase 13 expression in osteoblastic cells: role of sirtuin 1 in the action of PTH on osteoblasts.
Volume: 290
Issue: 13
Pages: 8373-82
Publication
First Author: Ionescu A
Year: 2012
Journal: Dev Cell
Title: FoxA family members are crucial regulators of the hypertrophic chondrocyte differentiation program.
Volume: 22
Issue: 5
Pages: 927-39
Publication
First Author: McDermott BT
Year: 2016
Journal: Osteoarthritis Cartilage
Title: RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes.
Volume: 24
Issue: 7
Pages: 1263-73
Publication
First Author: Shen J
Year: 2013
Journal: Arthritis Rheum
Title: Deletion of the transforming growth factor β receptor type II gene in articular chondrocytes leads to a progressive osteoarthritis-like phenotype in mice.
Volume: 65
Issue: 12
Pages: 3107-19
Publication
First Author: Ma O
Year: 2009
Journal: Cancer Res
Title: MMP13, Birc2 (cIAP1), and Birc3 (cIAP2), amplified on chromosome 9, collaborate with p53 deficiency in mouse osteosarcoma progression.
Volume: 69
Issue: 6
Pages: 2559-67
Publication
First Author: Inada M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Critical roles for collagenase-3 (Mmp13) in development of growth plate cartilage and in endochondral ossification.
Volume: 101
Issue: 49
Pages: 17192-7
Publication
First Author: Hirata M
Year: 2012
Journal: Hum Mol Genet
Title: C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.
Volume: 21
Issue: 5
Pages: 1111-23
Publication
First Author: Pratap J
Year: 2005
Journal: Mol Cell Biol
Title: The Runx2 osteogenic transcription factor regulates matrix metalloproteinase 9 in bone metastatic cancer cells and controls cell invasion.
Volume: 25
Issue: 19
Pages: 8581-91
Publication
First Author: Stickens D
Year: 2004
Journal: Development
Title: Altered endochondral bone development in matrix metalloproteinase 13-deficient mice.
Volume: 131
Issue: 23
Pages: 5883-95
Publication
First Author: Smith LR
Year: 2020
Journal: Cell Physiol Biochem
Title: Matrix Metalloproteinase 13 from Satellite Cells is Required for Efficient Muscle Growth and Regeneration.
Volume: 54
Issue: 3
Pages: 333-353
Publication
First Author: Juncker-Jensen A
Year: 2011
Journal: PLoS One
Title: Phenotypic overlap between MMP-13 and the plasminogen activation system during wound healing in mice.
Volume: 6
Issue: 2
Pages: e16954
Publication
First Author: Lieu S
Year: 2011
Journal: Dis Model Mech
Title: Impaired remodeling phase of fracture repair in the absence of matrix metalloproteinase-2.
Volume: 4
Issue: 2
Pages: 203-11
Publication  
First Author: Koop K
Year: 2023
Journal: Front Immunol
Title: Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis.
Volume: 14
Pages: 1163198
Publication
First Author: Bouaziz W
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Interaction of HIF1α and β-catenin inhibits matrix metalloproteinase 13 expression and prevents cartilage damage in mice.
Volume: 113
Issue: 19
Pages: 5453-8
Publication  
First Author: Li T
Year: 2019
Journal: Sci Transl Med
Title: TGF-β type 2 receptor-mediated modulation of the IL-36 family can be therapeutically targeted in osteoarthritis.
Volume: 11
Issue: 491
Publication
First Author: Jin JZ
Year: 2014
Journal: Int J Dev Biol
Title: Regional divergence of palate medial edge epithelium along the anterior to posterior axis.
Volume: 58
Issue: 9
Pages: 713-7
Publication
First Author: Takarada T
Year: 2009
Journal: Neurosci Lett
Title: Transactivation by Runt related factor-2 of matrix metalloproteinase-13 in astrocytes.
Volume: 451
Issue: 2
Pages: 99-104
Publication
First Author: Ruengsinpinya L
Year: 2020
Journal: Biochem Biophys Res Commun
Title: G protein subunit β1 is an important mediator of the late stage of endochondral ossification.
Volume: 533
Issue: 1
Pages: 90-96
Publication
First Author: Whitaker AT
Year: 2017
Journal: Biol Open
Title: Smad4 regulates growth plate matrix production and chondrocyte polarity.
Volume: 6
Issue: 3
Pages: 358-364
Publication
First Author: Heinonen J
Year: 2017
Journal: Osteoarthritis Cartilage
Title: Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.
Volume: 25
Issue: 7
Pages: 1132-1142
Publication
First Author: Sugita S
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Transcription factor Hes1 modulates osteoarthritis development in cooperation with calcium/calmodulin-dependent protein kinase 2.
Volume: 112
Issue: 10
Pages: 3080-5
Publication
First Author: Nishimura R
Year: 2012
Journal: J Biol Chem
Title: Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification.
Volume: 287
Issue: 40
Pages: 33179-90
Publication
First Author: Madala SK
Year: 2010
Journal: J Immunol
Title: Matrix metalloproteinase 12-deficiency augments extracellular matrix degrading metalloproteinases and attenuates IL-13-dependent fibrosis.
Volume: 184
Issue: 7
Pages: 3955-63
Publication
First Author: Aizawa R
Year: 2012
Journal: Mech Dev
Title: Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development.
Volume: 129
Issue: 1-4
Pages: 38-50
Publication
First Author: Zhang C
Year: 2012
Journal: PLoS One
Title: Matrix metalloproteinase 13 (MMP13) is a direct target of osteoblast-specific transcription factor osterix (Osx) in osteoblasts.
Volume: 7
Issue: 11
Pages: e50525
Publication  
First Author: Shin M
Year: 2022
Journal: Bone
Title: Mesenchymal cell TRPM7 expression is required for bone formation via the regulation of chondrogenesis.
Volume: 166
Pages: 116579
Publication  
First Author: Jáuregui EJ
Year: 2016
Journal: Bone
Title: Parallel mechanisms suppress cochlear bone remodeling to protect hearing.
Volume: 89
Pages: 7-15
Publication  
First Author: Varadinkova S
Year: 2023
Journal: Front Cell Dev Biol
Title: Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.
Volume: 11
Pages: 1168866
Publication
First Author: Lane J
Year: 2015
Journal: Dev Biol
Title: Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development.
Volume: 398
Issue: 2
Pages: 231-41
Publication
First Author: Saito T
Year: 2010
Journal: Nat Med
Title: Transcriptional regulation of endochondral ossification by HIF-2alpha during skeletal growth and osteoarthritis development.
Volume: 16
Issue: 6
Pages: 678-86
Publication
First Author: Ferguson C
Year: 1999
Journal: Mech Dev
Title: Does adult fracture repair recapitulate embryonic skeletal formation?
Volume: 87
Issue: 1-2
Pages: 57-66
Publication  
First Author: Niebler S
Year: 2015
Journal: Arthritis Res Ther
Title: Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development.
Volume: 17
Pages: 119
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Henriet P
Year: 1992
Journal: FEBS Lett
Title: Cloning and sequencing of mouse collagenase cDNA. Divergence of mouse and rat collagenases from the other mammalian collagenases.
Volume: 310
Issue: 2
Pages: 175-8
Publication
First Author: Toriseva M
Year: 2012
Journal: PLoS One
Title: MMP-13 regulates growth of wound granulation tissue and modulates gene expression signatures involved in inflammation, proteolysis, and cell viability.
Volume: 7
Issue: 8
Pages: e42596
Publication
First Author: Pagenstecher A
Year: 1998
Journal: Am J Pathol
Title: Differential expression of matrix metalloproteinase and tissue inhibitor of matrix metalloproteinase genes in the mouse central nervous system in normal and inflammatory states.
Volume: 152
Issue: 3
Pages: 729-41
Publication
First Author: Hao X
Year: 2023
Journal: Cell Stem Cell
Title: Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal.
Volume: 30
Issue: 5
Pages: 648-664.e8
Publication
First Author: Zigrino P
Year: 2009
Journal: J Invest Dermatol
Title: Stromal expression of MMP-13 is required for melanoma invasion and metastasis.
Volume: 129
Issue: 11
Pages: 2686-93
Publication  
First Author: Ma F
Year: 2016
Journal: Neurobiol Dis
Title: Matrix metalloproteinase-13 participates in neuroprotection and neurorepair after cerebral ischemia in mice.
Volume: 91
Pages: 236-46
Publication
First Author: Fu J
Year: 2016
Journal: J Clin Invest
Title: Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease.
Volume: 126
Issue: 5
Pages: 1759-72