Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Matrix metalloproteinases (MMPs) degrade most components of the extracellular matrix (ECM) and process a number of bioactive molecules.Matrix metalloproteinase-19 (MMP19) degrades various components of the extracellular matrix, such as aggrecan and cartilage oligomeric matrix protein (comp), during development, haemostasis and pathological conditions (arthritic disease) [, ]. It may also play a role in neovascularization or angiogenesis []. MMP19 hydrolyses collagen type IV, laminin, nidogen, nascin-C isoform, fibronectin, and type I gelatin []. Its expression has been linked to melanoma progression []. |
|
•
•
•
•
•
|
Publication |
First Author: |
Jost M |
Year: |
2006 |
Journal: |
Cancer Res |
Title: |
Earlier onset of tumoral angiogenesis in matrix metalloproteinase-19-deficient mice. |
Volume: |
66 |
Issue: |
10 |
Pages: |
5234-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Beck IM |
Year: |
2008 |
Journal: |
PLoS One |
Title: |
MMP19 is essential for T cell development and T cell-mediated cutaneous immune responses. |
Volume: |
3 |
Issue: |
6 |
Pages: |
e2343 |
|
•
•
•
•
•
|
Publication |
First Author: |
Müller M |
Year: |
2010 |
Journal: |
Mod Pathol |
Title: |
MMP19 is upregulated during melanoma progression and increases invasion of melanoma cells. |
Volume: |
23 |
Issue: |
4 |
Pages: |
511-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sedlacek R |
Year: |
1998 |
Journal: |
Immunobiology |
Title: |
Matrix metalloproteinase MMP-19 (RASI-1) is expressed on the surface of activated peripheral blood mononuclear cells and is detected as an autoantigen in rheumatoid arthritis. |
Volume: |
198 |
Issue: |
4 |
Pages: |
408-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stracke JO |
Year: |
2000 |
Journal: |
J Biol Chem |
Title: |
Biochemical characterization of the catalytic domain of human matrix metalloproteinase 19. Evidence for a role as a potent basement membrane degrading enzyme. |
Volume: |
275 |
Issue: |
20 |
Pages: |
14809-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stracke JO |
Year: |
2000 |
Journal: |
FEBS Lett |
Title: |
Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP). |
Volume: |
478 |
Issue: |
1-2 |
Pages: |
52-6 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
527
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
520
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
455
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Jirouskova M |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Hepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosis. |
Volume: |
7 |
Issue: |
10 |
Pages: |
e46271 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brauer R |
Year: |
2016 |
Journal: |
Mucosal Immunol |
Title: |
MMP-19 deficiency causes aggravation of colitis due to defects in innate immune cell function. |
Volume: |
9 |
Issue: |
4 |
Pages: |
974-85 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Mueller MS |
Year: |
2000 |
Journal: |
Gene |
Title: |
The murine ortholog of matrix metalloproteinase 19: its cloning, gene organization, and expression. |
Volume: |
256 |
Issue: |
1-2 |
Pages: |
101-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pendás AM |
Year: |
2004 |
Journal: |
Mol Cell Biol |
Title: |
Diet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase 19-deficient mice. |
Volume: |
24 |
Issue: |
12 |
Pages: |
5304-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jara P |
Year: |
2015 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Matrix metalloproteinase (MMP)-19-deficient fibroblasts display a profibrotic phenotype. |
Volume: |
308 |
Issue: |
6 |
Pages: |
L511-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gueders MM |
Year: |
2010 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Matrix metalloproteinase-19 deficiency promotes tenascin-C accumulation and allergen-induced airway inflammation. |
Volume: |
43 |
Issue: |
3 |
Pages: |
286-95 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
testis |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
kidney |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
skeletal muscle |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
liver |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
lung |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
spleen |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
brain |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1930942 |
Assay Type: |
Northern blot |
Annotation Date: |
2003-05-16 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:2658841 |
Age: |
postnatal adult |
|
|
Specimen Label: |
heart |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7526065 |
Age: |
embryonic day 18.5 |
Image: |
4 |
|
Specimen Label: |
EpCAM+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283426 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7526065 |
Age: |
embryonic day 18.5 |
Image: |
4 |
|
Specimen Label: |
EpCAM-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1925226 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7526074 |
Age: |
embryonic day 18.5 |
Image: |
4 |
|
Specimen Label: |
EpCAM+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1925226 |
|
Stage: |
TS26 |
Assay Id: |
MGI:7526074 |
Age: |
embryonic day 18.5 |
Image: |
4 |
|
Specimen Label: |
EpCAM-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526079 |
Age: |
postnatal day 0 |
Image: |
4 |
|
Specimen Label: |
EpCAM+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526079 |
Age: |
postnatal day 0 |
Image: |
4 |
|
Specimen Label: |
EpCAM-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1925227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526086 |
Age: |
postnatal day 0 |
Image: |
4 |
|
Specimen Label: |
EpCAM+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1925227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526086 |
Age: |
postnatal day 0 |
Image: |
4 |
|
Specimen Label: |
EpCAM-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526099 |
Age: |
postnatal day 3 |
Image: |
4 |
|
Specimen Label: |
EpCAM+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283427 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526099 |
Age: |
postnatal day 3 |
Image: |
4 |
|
Specimen Label: |
EpCAM-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1925227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526106 |
Age: |
postnatal day 3 |
Image: |
4 |
|
Specimen Label: |
EpCAM+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7525618 |
Assay Type: |
RT-PCR |
Annotation Date: |
2023-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1925227 |
|
Stage: |
TS27 |
Assay Id: |
MGI:7526106 |
Age: |
postnatal day 3 |
Image: |
4 |
|
Specimen Label: |
EpCAM-/- |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hurskainen T |
Year: |
2000 |
Journal: |
GenBank Submission |
Title: |
Mus musculus matrix metalloproteinase-19 mRNA, complete cds |
|
|
Pages: |
AF162446 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nalvarte I |
Year: |
2016 |
Journal: |
Reproduction |
Title: |
Estrogen receptor β controls MMP-19 expression in mouse ovaries during ovulation. |
Volume: |
151 |
Issue: |
3 |
Pages: |
253-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caterina JJ |
Year: |
2000 |
Journal: |
Mol Biol Rep |
Title: |
Characterization, expression analysis and chromosomal mapping of mouse matrix metalloproteinase-19 (MMP-19). |
Volume: |
27 |
Issue: |
2 |
Pages: |
73-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vanden Berghe T |
Year: |
2015 |
Journal: |
Immunity |
Title: |
Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice. |
Volume: |
43 |
Issue: |
1 |
Pages: |
200-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Newby AC |
Year: |
2015 |
Journal: |
Matrix Biol |
Title: |
Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation. |
Volume: |
44-46 |
|
Pages: |
157-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nuttall RK |
Year: |
2004 |
Journal: |
FEBS Lett |
Title: |
Expression analysis of the entire MMP and TIMP gene families during mouse tissue development. |
Volume: |
563 |
Issue: |
1-3 |
Pages: |
129-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tocchi A |
Year: |
2013 |
Journal: |
FEBS J |
Title: |
Functional interactions between matrix metalloproteinases and glycosaminoglycans. |
Volume: |
280 |
Issue: |
10 |
Pages: |
2332-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Seo S |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Forkhead box transcription factor FoxC1 preserves corneal transparency by regulating vascular growth. |
Volume: |
109 |
Issue: |
6 |
Pages: |
2015-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perez SE |
Year: |
2005 |
Journal: |
Diabetes |
Title: |
Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo. |
Volume: |
54 |
Issue: |
3 |
Pages: |
694-701 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kobielak A |
Year: |
2006 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Links between alpha-catenin, NF-kappaB, and squamous cell carcinoma in skin. |
Volume: |
103 |
Issue: |
7 |
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