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Search results 1 to 100 out of 135 for Mmp20

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Type Details Score
Gene
9313 | MMP20
Type: gene
Organism: human
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Protein
Q3LRH7
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Gene
703188 | MMP20
Type: gene
Organism: macaque, rhesus
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Gene
100489409 | mmp20
Type: gene
Organism: frog, western clawed
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Gene
281916 | MMP20
Type: gene
Organism: cattle
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Gene
300341 | Mmp20
Type: gene
Organism: rat
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Gene
611829 | MMP20
Type: gene
Organism: dog, domestic
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Gene
740407 | MMP20
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1353466 | Mmp20
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR028716 | MMP20
Type: Family
Description: Matrix metalloproteinases (MMPs) degrade most components of the extracellular matrix (ECM) and process a number of bioactive molecules. Matrix metalloproteinase-20 (MMP20, also known as enamelysin; MEROPS identifier M10.019) degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterising the cartilage extracellular matrix: aggrecan and the cartilage oligomeric matrix protein (COMP) [, ]. It facilitates ameloblast movements during enamel development and plays a central role in tooth enamel formation [, ].Mutations in MMP20 gene cause amelogenesis imperfecta, hypomaturation type, 2A2 (AI2A2), which is a defect of enamel formation [].
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Gene
101928477 | MMP20-AS1
Type: gene
Organism: human
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Publication
24067343 | -
First Author: Guan X
Year: 2013
Journal: J Dent Res
Title: MMP20 modulates cadherin expression in ameloblasts as enamel develops.
Volume: 92
Issue: 12
Pages: 1123-8
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Publication
21386097 | J:278761
First Author: Sharma R
Year: 2011
Journal: J Dent Res
Title: Assessment of dental fluorosis in Mmp20 +/- mice.
Volume: 90
Issue: 6
Pages: 788-92
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Publication
21144496 | J:174111
First Author: Küchler EC
Year: 2011
Journal: Arch Oral Biol
Title: MMP1 and MMP20 contribute to tooth agenesis in humans.
Volume: 56
Issue: 5
Pages: 506-11
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Publication
20929715 | J:323258
First Author: Tye CE
Year: 2010
Journal: J Dent Res
Title: Altered ion-responsive gene expression in Mmp20 null mice.
Volume: 89
Issue: 12
Pages: 1421-6
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Publication
22243248 | J:199350
 
First Author: Yamakoshi Y
Year: 2011
Journal: Eur J Oral Sci
Title: Enamel proteins and proteases in Mmp20 and Klk4 null and double-null mice.
Volume: 119 Suppl 1
Pages: 206-16
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Publication
16548514 | -
First Author: Turk BE
Year: 2006
Journal: Biochemistry
Title: MMP-20 is predominately a tooth-specific enzyme with a deep catalytic pocket that hydrolyzes type V collagen.
Volume: 45
Issue: 12
Pages: 3863-74
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Publication
9398237 | -
First Author: Llano E
Year: 1997
Journal: Biochemistry
Title: Identification and structural and functional characterization of human enamelysin (MMP-20).
Volume: 36
Issue: 49
Pages: 15101-8
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Publication
23053846 | -
First Author: Bartlett JD
Year: 2013
Journal: J Dent Res
Title: Modulation of cell-cell junctional complexes by matrix metalloproteinases.
Volume: 92
Issue: 1
Pages: 10-7
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Publication
15744043 | -
First Author: Kim JW
Year: 2005
Journal: J Med Genet
Title: MMP-20 mutation in autosomal recessive pigmented hypomaturation amelogenesis imperfecta.
Volume: 42
Issue: 3
Pages: 271-5
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Publication
10922468 | -
First Author: Stracke JO
Year: 2000
Journal: FEBS Lett
Title: Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP).
Volume: 478
Issue: 1-2
Pages: 52-6
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Protein
P57748
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
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Publication
24466234 | J:206207
First Author: Shin M
Year: 2014
Journal: PLoS One
Title: Matrix metalloproteinase-20 over-expression is detrimental to enamel development: a Mus musculus model.
Volume: 9
Issue: 1
Pages: e86774
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Publication
29535349 | J:259442
First Author: Niwa T
Year: 2018
Journal: Sci Rep
Title: The dynamics of TGF-β in dental pulp, odontoblasts and dentin.
Volume: 8
Issue: 1
Pages: 4450
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Publication
34012043 | J:306286
First Author: Bartlett JD
Year: 2021
Journal: Sci Rep
Title: MMP20-generated amelogenin cleavage products prevent formation of fan-shaped enamel malformations.
Volume: 11
Issue: 1
Pages: 10570
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Publication
21454549 | J:172681
First Author: Smith CE
Year: 2011
Journal: J Biol Chem
Title: Effect of kallikrein 4 loss on enamel mineralization: comparison with mice lacking matrix metalloproteinase 20.
Volume: 286
Issue: 20
Pages: 18149-60
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Publication
27066511 | J:258669
First Author: Hu Y
Year: 2016
Journal: Mol Genet Genomic Med
Title: MMP20, KLK4, and MMP20/KLK4 double null mice define roles for matrix proteases during dental enamel formation.
Volume: 4
Issue: 2
Pages: 178-96
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Publication
22243238 | J:268514
 
First Author: Smith CE
Year: 2011
Journal: Eur J Oral Sci
Title: Relationships between protein and mineral during enamel development in normal and genetically altered mice.
Volume: 119 Suppl 1
Pages: 125-35
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Publication
30929801 | J:290672
First Author: Okubo M
Year: 2019
Journal: J Oral Biosci
Title: Potential function of TGF-β isoforms in maturation-stage ameloblasts.
Volume: 61
Issue: 1
Pages: 43-54
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Protein Coding Gene
MGP_CAROLIEiJ_G0031758 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034326 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034298 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034009 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1353466 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034820 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033337 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034084 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034225 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034128 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034839 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033040 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014636 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032878 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12393861 | J:80925
First Author: Caterina JJ
Year: 2002
Journal: J Biol Chem
Title: Enamelysin (matrix metalloproteinase 20)-deficient mice display an amelogenesis imperfecta phenotype.
Volume: 277
Issue: 51
Pages: 49598-604
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Publication
15557396 | J:95072
First Author: Bartlett JD
Year: 2004
Journal: J Dent Res
Title: Decreased mineral content in MMP-20 null mouse enamel is prominent during the maturation stage.
Volume: 83
Issue: 12
Pages: 909-13
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Publication
16674658 | J:145683
 
First Author: Beniash E
Year: 2006
Journal: Eur J Oral Sci
Title: Formation of the dentino-enamel interface in enamelysin (MMP-20)-deficient mouse incisors.
Volume: 114 Suppl 1
Pages: 24-9; discussion 39-41, 379
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Publication
11023266 | J:74065
First Author: Caterina J
Year: 2000
Journal: J Dent Res
Title: Cloning, characterization, and expression analysis of mouse enamelysin.
Volume: 79
Issue: 9
Pages: 1697-703
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Heart
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Liver
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Kidney
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Brain
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3278228
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Bone
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Muscle
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1640522
Stage: TS22
Assay Id: MGI:4420431
Age: embryonic day 14.5
Specimen Label: Limb (14.5 dpc)
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1721422
Stage: TS22
Assay Id: MGI:4420431
Age: embryonic day 14.5
Specimen Label: Axial Skeleton (14.5)
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:4420428
Assay Type: Northern blot
Annotation Date: 2010-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288928
Stage: TS28
Assay Id: MGI:4420431
Age: postnatal week 3
Specimen Label: Incisor
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793925
Stage: TS25
Assay Id: MGI:4849221
Age: embryonic day 17.5
Specimen Label: E17.5 tip
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793925
Stage: TS25
Assay Id: MGI:4849221
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793927
Stage: TS27
Assay Id: MGI:4849221
Age: postnatal day 0
Specimen Label: P0 tip
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793927
Stage: TS27
Assay Id: MGI:4849221
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793927
Stage: TS27
Assay Id: MGI:4849221
Age: postnatal day 1
Specimen Label: P1 tip
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793927
Stage: TS27
Assay Id: MGI:4849221
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793927
Stage: TS27
Assay Id: MGI:4849221
Age: postnatal day 2
Specimen Label: P2 tip
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793927
Stage: TS27
Assay Id: MGI:4849221
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793928
Stage: TS28
Assay Id: MGI:4849221
Age: postnatal day 10
Specimen Label: P10 tip
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:4848083
Assay Type: RT-PCR
Annotation Date: 2010-12-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1793928
Stage: TS28
Assay Id: MGI:4849221
Age: postnatal day 10
Specimen Label: P10
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:4420429
Assay Type: RNA in situ
Annotation Date: 2010-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1792127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:4420432
Age: postnatal day 3
Note: Expression is in ameloblasts and odontoblasts.
Specimen Label: 4A,B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4420429
Assay Type: RNA in situ
Annotation Date: 2010-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:4420432
Age: postnatal day 3
Note: Expression is in ameloblasts.
Specimen Label: 4A,B
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6361551
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6363084
Age: postnatal month 2
Specimen Label: 6D WT secretory
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6361551
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3288828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6363084
Age: postnatal month 2
Specimen Label: 6D KO secretory
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6361551
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3288828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6363084
Age: postnatal month 2
Specimen Label: 6D WT maturation
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6361551
Assay Type: Immunohistochemistry
Annotation Date: 2019-10-09
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3288828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6363084
Age: postnatal month 2
Specimen Label: 6D KO maturation
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:4420429
Assay Type: RNA in situ
Annotation Date: 2010-02-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1829027
Stage: TS27
Assay Id: MGI:4420432
Age: postnatal day 3
Note: Absent in the alveolar bone or in other areas of the dental sac or pulp.
Specimen Label: 4A,B
Detected: false
Specimen Num: 1
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Publication
16674657 | J:145684
 
First Author: Bartlett JD
Year: 2006
Journal: Eur J Oral Sci
Title: A developmental comparison of matrix metalloproteinase-20 and amelogenin null mouse enamel.
Volume: 114 Suppl 1
Pages: 18-23; discussion 39-41, 379
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Publication
16998127 | J:267865
First Author: Bartlett JD
Year: 2006
Journal: J Dent Res
Title: Origin, splicing, and expression of rodent amelogenin exon 8.
Volume: 85
Issue: 10
Pages: 894-9
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Publication
15296943 | J:92108
First Author: Väänänen A
Year: 2004
Journal: Matrix Biol
Title: Expression of collagen XVIII and MMP-20 in developing teeth and odontogenic tumors.
Volume: 23
Issue: 3
Pages: 153-61
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Publication
15748894 | J:98200
First Author: Bourd-Boittin K
Year: 2005
Journal: Exp Cell Res
Title: Matrix metalloproteinase inhibition impairs the processing, formation and mineralization of dental tissues during mouse molar development.
Volume: 304
Issue: 2
Pages: 493-505
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Publication
10610728 | J:60096
First Author: Caterina J
Year: 1999
Journal: Genomics
Title: Isolation, characterization, and chromosomal location of the mouse enamelysin gene.
Volume: 62
Issue: 2
Pages: 308-11
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Publication
- | J:219404
     
First Author: Klaften M
Year: 2006
Journal: PhD Thesis - HelmholtzZentrum München
Title: Ein neuartiges Konzept zur genomweiten Kartierung von ENU-induzierten Mausmutanten in Hochdurchsatz.
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Publication
20147630 | J:219403
First Author: Mirabella F
Year: 2010
Journal: J Immunol
Title: The human IL-3/granulocyte-macrophage colony-stimulating factor locus is epigenetically silent in immature thymocytes and is progressively activated during T cell development.
Volume: 184
Issue: 6
Pages: 3043-54
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Publication
29684584 | J:270176
First Author: Tian Z
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Deletion of epithelial cell-specific Cdc42 leads to enamel hypermaturation in a conditional knockout mouse model.
Volume: 1864
Issue: 8
Pages: 2623-2632
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Publication
22351765 | J:184287
First Author: Duverger O
Year: 2012
Journal: J Biol Chem
Title: Neural crest deletion of Dlx3 leads to major dentin defects through down-regulation of Dspp.
Volume: 287
Issue: 15
Pages: 12230-40
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Publication
15525533 | J:94518
First Author: Wang XP
Year: 2004
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