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Search results 1 to 100 out of 101 for Mob1a

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Type Details Score
Gene
55233 | MOB1A
Type: gene
Organism: human
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Gene
612924 | MOB1A
Type: gene
Organism: dog, domestic
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Gene
614611 | MOB1A
Type: gene
Organism: cattle
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Gene
429657 | MOB1A
Type: gene
Organism: chicken
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Gene
100005014 | mob1a
Type: gene
Organism: zebrafish
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Gene
707984 | MOB1A
Type: gene
Organism: macaque, rhesus
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Gene
549780 | mob1a
Type: gene
Organism: frog, western clawed
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Gene
297387 | Mob1a
Type: gene
Organism: rat
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Gene
459544 | MOB1A
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2442631 | Mob1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23143302 | J:193981
First Author: Nishio M
Year: 2012
Journal: J Clin Invest
Title: Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice.
Volume: 122
Issue: 12
Pages: 4505-18
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Protein Coding Gene
MGP_CAROLIEiJ_G0028554 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030898 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0030826 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030908 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0030802 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2442631 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0031368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0030017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0030595 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0030748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0030701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0030827 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0030737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0031392 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0029732 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0030098 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0022289 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0029560 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
30640535 | J:289144
First Author: Nishio M
Year: 2019
Journal: FASEB J
Title: Hippo pathway controls cell adhesion and context-dependent cell competition to influence skin engraftment efficiency.
Volume: 33
Issue: 4
Pages: 5548-5560
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Publication
31125466 | J:295815
First Author: Kato W
Year: 2019
Journal: Genes Cells
Title: MOB1 regulates thymocyte egress and T-cell survival in mice in a YAP1-independent manner.
Volume: 24
Issue: 7
Pages: 485-495
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GXD Expression
GXD Expression
     
Probe: MGI:7387069
Assay Type: Western blot
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Stage: TS22
Assay Id: MGI:7387070
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7387069
Assay Type: Western blot
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:7387070
Age: embryonic day 16.5
Specimen Label: E16.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7387069
Assay Type: Western blot
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:7387070
Age: embryonic day 17.5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7387069
Assay Type: Western blot
Annotation Date: 2022-11-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672826
Stage: TS26
Assay Id: MGI:7387070
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Stage: TS23
Assay Id: MGI:7565515
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Stage: TS27
Assay Id: MGI:7565515
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Stage: TS27
Assay Id: MGI:7565515
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7565515
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7565515
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7565515
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7565515
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7565515
Age: postnatal day 28
Specimen Label: P28
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:7565515
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Stage: TS23
Assay Id: MGI:7565517
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:7565517
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:7565517
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7565517
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7565517
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7565517
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7565517
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7565517
Age: postnatal day 28
Specimen Label: P28
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:7565463
Assay Type: Western blot
Annotation Date: 2023-12-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:7565517
Age: postnatal adult
Specimen Label: Adult
Detected: true
Specimen Num: 9
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Publication
30349003 | J:288139
First Author: Bae JS
Year: 2018
Journal: Cell Death Dis
Title: Depletion of MOB1A/B causes intestinal epithelial degeneration by suppressing Wnt activity and activating BMP/TGF-β signaling.
Volume: 9
Issue: 11
Pages: 1083
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Publication
28346423 | J:243360
First Author: Otsubo K
Year: 2017
Journal: Oncogene
Title: MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation.
Volume: 36
Issue: 29
Pages: 4201-4211
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Publication
32206709 | J:287695
First Author: Omori H
Year: 2020
Journal: Sci Adv
Title: YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma.
Volume: 6
Issue: 12
Pages: eaay3324
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Publication
18328708 | J:135359
First Author: Praskova M
Year: 2008
Journal: Curr Biol
Title: MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation.
Volume: 18
Issue: 5
Pages: 311-21
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Publication
28681838 | J:252240
 
First Author: Miyamura N
Year: 2017
Journal: Nat Commun
Title: YAP determines the cell fate of injured mouse hepatocytes in vivo.
Volume: 8
Pages: 16017
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Publication
35858357 | J:332523
First Author: Soyama H
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers.
Volume: 119
Issue: 29
Pages: e2123134119
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Publication
32716083 | J:299883
First Author: Nishio M
Year: 2020
Journal: Cancer Sci
Title: Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice.
Volume: 111
Issue: 10
Pages: 3576-3587
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Publication
29511023 | J:260465
 
First Author: Goto H
Year: 2018
Journal: Development
Title: Loss of Mob1a/b in mice results in chondrodysplasia due to YAP1/TAZ-TEAD-dependent repression of SOX9.
Volume: 145
Issue: 6
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Publication
30069702 | J:316118
First Author: Song Z
Year: 2018
Journal: Cell Mol Life Sci
Title: PTEN-GSK3β-MOB1 axis controls neurite outgrowth in vitro and in vivo.
Volume: 75
Issue: 23
Pages: 4445-4464
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Publication
26699479 | J:228499
First Author: Nishio M
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice.
Volume: 113
Issue: 1
Pages: E71-80
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Publication
29632206 | J:261328
First Author: Zou J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Volume: 115
Issue: 17
Pages: E4101-E4110
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Mob1a<em2Smoc> | MGI:7291127
Name: MOB kinase activator 1A; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Mob1a<em1Smoc> | MGI:7291126
Name: MOB kinase activator 1A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Strain
MGI:6429195 | C57BL/6J-Mob1a<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein Domain
IPR028741 | LATS1
Type: Family
Description: There are two mammalian homologue of Drosophila tumor suppressor Lats (large tumor suppressor, also known as Warts): LATS1 and LATS2. Lats/Warts is a serine/threonine-protein kinase that negatively regulates YAP1 (Drosophila Yorkie (Yki) homologue) in the Hippo signaling pathway, which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis [, ]. This entry represents LATS1 from mammals. During cell division, LATS1 interacts with MOB1A and serves as a mitotic exit network kinase [].
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Publication
18158288 | -
First Author: Hao Y
Year: 2008
Journal: J Biol Chem
Title: Tumor suppressor LATS1 is a negative regulator of oncogene YAP.
Volume: 283
Issue: 9
Pages: 5496-509
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Publication
16061636 | -
First Author: Bothos J
Year: 2005
Journal: Cancer Res
Title: Human LATS1 is a mitotic exit network kinase.
Volume: 65
Issue: 15
Pages: 6568-75
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Publication
16096061 | -
First Author: Huang J
Year: 2005
Journal: Cell
Title: The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP.
Volume: 122
Issue: 3
Pages: 421-34
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