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Search results 1 to 100 out of 432 for Mpc1

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0.037s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Grenell A
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Loss of MPC1 reprograms retinal metabolism to impair visual function.
Volume: 116
Issue: 9
Pages: 3530-3535
Publication
First Author: Zou S
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Fatty acid oxidation alleviates the energy deficiency caused by the loss of MPC1 in MPC1+/- mice.
Volume: 495
Issue: 1
Pages: 1008-1013
Publication
First Author: Bricker DK
Year: 2012
Journal: Science
Title: A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
Volume: 337
Issue: 6090
Pages: 96-100
Publication
First Author: Gray LR
Year: 2015
Journal: Cell Metab
Title: Hepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.
Volume: 22
Issue: 4
Pages: 669-81
Publication
First Author: Petrelli F
Year: 2023
Journal: Sci Adv
Title: Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells.
Volume: 9
Issue: 9
Pages: eadd5220
Publication
First Author: Herzig S
Year: 2012
Journal: Science
Title: Identification and functional expression of the mitochondrial pyruvate carrier.
Volume: 337
Issue: 6090
Pages: 93-6
Publication
First Author: Ramstead AG
Year: 2020
Journal: Cell Rep
Title: Mitochondrial Pyruvate Carrier 1 Promotes Peripheral T Cell Homeostasis through Metabolic Regulation of Thymic Development.
Volume: 30
Issue: 9
Pages: 2889-2899.e6
Publication
First Author: Li X
Year: 2016
Journal: Oncotarget
Title: Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses.
Volume: 7
Issue: 48
Pages: 79981-79994
Publication
First Author: Bensard CL
Year: 2020
Journal: Cell Metab
Title: Regulation of Tumor Initiation by the Mitochondrial Pyruvate Carrier.
Volume: 31
Issue: 2
Pages: 284-300.e7
Publication  
First Author: Shannon CE
Year: 2024
Journal: Mol Metab
Title: The mitochondrial pyruvate carrier regulates adipose glucose partitioning in female mice.
Volume: 88
Pages: 102005
Publication
First Author: Vanderperre B
Year: 2016
Journal: PLoS Genet
Title: Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.
Volume: 12
Issue: 5
Pages: e1006056
Publication
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Rauckhorst AJ
Year: 2017
Journal: Mol Metab
Title: The mitochondrial pyruvate carrier mediates high fat diet-induced increases in hepatic TCA cycle capacity.
Volume: 6
Issue: 11
Pages: 1468-1479
Publication
First Author: Tompkins SC
Year: 2019
Journal: Cell Rep
Title: Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis.
Volume: 28
Issue: 10
Pages: 2608-2619.e6
Publication
First Author: Guo Y
Year: 2021
Journal: Nat Immunol
Title: Metabolic reprogramming of terminally exhausted CD8(+) T cells by IL-10 enhances anti-tumor immunity.
Volume: 22
Issue: 6
Pages: 746-756
Publication
First Author: Ekiz HA
Year: 2020
Journal: J Immunol
Title: T Cell-Expressed microRNA-155 Reduces Lifespan in a Mouse Model of Age-Related Chronic Inflammation.
Volume: 204
Issue: 8
Pages: 2064-2075
Publication
First Author: Fink BD
Year: 2018
Journal: J Biol Chem
Title: Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration.
Volume: 293
Issue: 51
Pages: 19932-19941
Publication    
First Author: De La Rossa A
Year: 2022
Journal: Elife
Title: Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency.
Volume: 11
GXD Expression    
Probe: MGI:5908825
Assay Type: RT-PCR
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909401
Age: embryonic day 13.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5908825
Assay Type: RT-PCR
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909401
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/+
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5908825
Assay Type: RT-PCR
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909401
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/gt
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909403
Age: embryonic day 13.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909403
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/gt
Detected: false
Specimen Num: 2
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909403
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/gt
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: kidney
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: liver
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: muscle
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: lung
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: spleen
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: pancreas
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: brain
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5908834
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:5909406
Age: postnatal adult
Image: 1
Specimen Label: thymus
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:7628167
Age: embryonic day 17.5
Specimen Label: e17.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7628167
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7628167
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7628167
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7628167
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal day 28
Specimen Label: P28
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7628167
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:7628174
Age: embryonic day 17.5
Specimen Label: e17.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7628174
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7628174
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7628174
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610527
Stage: TS27
Assay Id: MGI:7628174
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal day 28
Specimen Label: P28
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:7628174
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684625
Stage: TS25
Assay Id: MGI:7628251
Age: embryonic day 17.5
Specimen Label: e17.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7628251
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7628251
Age: postnatal day 1
Specimen Label: P1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7628251
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684627
Stage: TS27
Assay Id: MGI:7628251
Age: postnatal day 3
Specimen Label: P3
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 5
Specimen Label: P5
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 7
Specimen Label: P7
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 14
Specimen Label: P14
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 21
Specimen Label: P21
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:7628069
Assay Type: Western blot
Annotation Date: 2024-05-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:7628251
Age: postnatal day 28
Specimen Label: P28
Detected: true
Specimen Num: 12