|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 112 for Mpc2

<< First    < Previous  |  Next >    Last >>
0.06s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
25874 | MPC2
Type: gene
Organism: human
•
•
•
•
•
Gene
748336 | MPC2
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
616718 | MPC2
Type: gene
Organism: cattle
•
•
•
•
•
Gene
100359982 | Mpc2
Type: gene
Organism: rat
•
•
•
•
•
Gene
768451 | MPC2
Type: gene
Organism: chicken
•
•
•
•
•
Gene
698807 | MPC2
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
549449 | mpc2
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
480086 | MPC2
Type: gene
Organism: dog, domestic
•
•
•
•
•
Protein Coding Gene
MGI:1917706 | Mpc2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
22628558 | J:185357
First Author: Bricker DK
Year: 2012
Journal: Science
Title: A mitochondrial pyruvate carrier required for pyruvate uptake in yeast, Drosophila, and humans.
Volume: 337
Issue: 6090
Pages: 96-100
•
•
•
•
•
Publication
24910426 | J:211781
First Author: Vigueira PA
Year: 2014
Journal: Cell Rep
Title: Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion.
Volume: 7
Issue: 6
Pages: 2042-2053
•
•
•
•
•
Publication
29126303 | J:255591
First Author: Chen Y
Year: 2018
Journal: Endocrinology
Title: Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid.
Volume: 159
Issue: 2
Pages: 609-621
•
•
•
•
•
Publication
22628554 | J:185358
First Author: Herzig S
Year: 2012
Journal: Science
Title: Identification and functional expression of the mitochondrial pyruvate carrier.
Volume: 337
Issue: 6090
Pages: 93-6
•
•
•
•
•
Publication
26344101 | J:236436
First Author: McCommis KS
Year: 2015
Journal: Cell Metab
Title: Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling.
Volume: 22
Issue: 4
Pages: 682-94
•
•
•
•
•
Publication
28597936 | J:280209
First Author: Vigueira PA
Year: 2017
Journal: Exp Physiol
Title: The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism.
Volume: 102
Issue: 8
Pages: 985-999
•
•
•
•
•
Publication
33106690 | J:325378
First Author: McCommis KS
Year: 2020
Journal: Nat Metab
Title: Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice.
Volume: 2
Issue: 11
Pages: 1232-1247
•
•
•
•
•
Publication
37716594 | J:340888
 
First Author: Yiew NKH
Year: 2023
Journal: Mol Metab
Title: Hepatic pyruvate and alanine metabolism are critical and complementary for maintenance of antioxidant capacity and resistance to oxidative insult.
Volume: 77
Pages: 101808
•
•
•
•
•
Publication
28154187 | J:241379
First Author: Vadvalkar SS
Year: 2017
Journal: J Biol Chem
Title: Decreased Mitochondrial Pyruvate Transport Activity in the Diabetic Heart: ROLE OF MITOCHONDRIAL PYRUVATE CARRIER 2 (MPC2) ACETYLATION.
Volume: 292
Issue: 11
Pages: 4423-4433
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0014805 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0016693 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0016674 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0016640 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0016635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0016459 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_1917706 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0017096 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0016039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0016434 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0016540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0016538 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0016611 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0016563 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0017132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0015825 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0016101 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0028042 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0015612 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
27396958 | J:259904
First Author: Lam WY
Year: 2016
Journal: Immunity
Title: Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells.
Volume: 45
Issue: 1
Pages: 60-73
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6719524
Assay Type: RT-PCR
Annotation Date: 2021-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6720320
Age: embryonic day 1.0
Specimen Label: Control
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6719524
Assay Type: RT-PCR
Annotation Date: 2021-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:6720320
Age: embryonic day 1.0
Specimen Label: Imp2-/+
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5908826
Assay Type: RT-PCR
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909402
Age: embryonic day 13.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5908826
Assay Type: RT-PCR
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909402
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/+
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5908826
Assay Type: RT-PCR
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909402
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/gt
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:5908837
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909404
Age: embryonic day 13.5
Image: 1
Specimen Label: +/+
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5908837
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909404
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/gt
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:5908837
Assay Type: Western blot
Annotation Date: 2017-09-18
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603921
Stage: TS21
Assay Id: MGI:5909404
Age: embryonic day 13.5
Image: 1
Specimen Label: gt/gt
Specimen Num: 3
•
•
•
•
•
Publication
37942005 | J:342356
First Author: Yiew NKH
Year: 2023
Journal: iScience
Title: Effects of hepatic mitochondrial pyruvate carrier deficiency on de novo lipogenesis and gluconeogenesis in mice.
Volume: 26
Issue: 11
Pages: 108196
•
•
•
•
•
Publication
34973337 | J:325377
First Author: Hodges WT
Year: 2022
Journal: J Biol Chem
Title: Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice.
Volume: 298
Issue: 2
Pages: 101554
•
•
•
•
•
Publication
25458843 | J:219501
First Author: Vacanti NM
Year: 2014
Journal: Mol Cell
Title: Regulation of substrate utilization by the mitochondrial pyruvate carrier.
Volume: 56
Issue: 3
Pages: 425-35
•
•
•
•
•
Publication
33824958 | J:314463
First Author: Tanaka K
Year: 2021
Journal: Biol Reprod
Title: Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes†.
Volume: 105
Issue: 1
Pages: 64-75
•
•
•
•
•
Publication
33106688 | J:338776
First Author: Fernandez-Caggiano M
Year: 2020
Journal: Nat Metab
Title: Mitochondrial pyruvate carrier abundance mediates pathological cardiac hypertrophy.
Volume: 2
Issue: 11
Pages: 1223-1231
•
•
•
•
•
Publication
27176894 | J:241329
First Author: Vanderperre B
Year: 2016
Journal: PLoS Genet
Title: Embryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.
Volume: 12
Issue: 5
Pages: e1006056
•
•
•
•
•
Publication
31406667 | J:302708
First Author: Liu HB
Year: 2019
Journal: Adv Sci (Weinh)
Title: RNA-Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation.
Volume: 6
Issue: 15
Pages: 1900295
•
•
•
•
•
Publication
27754788 | J:240750
First Author: Bose SK
Year: 2016
Journal: Endocrinology
Title: Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation.
Volume: 157
Issue: 12
Pages: 4943-4960
•
•
•
•
•
Publication
27760309 | J:240758
First Author: Duteil D
Year: 2016
Journal: Cell Rep
Title: Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.
Volume: 17
Issue: 4
Pages: 1008-1021
•
•
•
•
•
Publication
10051400 | J:52606
First Author: Eddleston J
Year: 1999
Journal: Genomics
Title: Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp).
Volume: 56
Issue: 2
Pages: 149-59
•
•
•
•
•
Publication
27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
•
•
•
•
•
Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
•
•
•
•
•
Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
•
•
•
•
•
Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Protein Coding Gene
MGI:1195985 | Cbx4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Allele
Mpc2<em2Smoc> | MGI:7291138
Name: mitochondrial pyruvate carrier 2; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Protein
O55187
Organism: Mus musculus/domesticus
Length: 551  
Fragment?: false
•
•
•
•
•
Protein
O55187-2
Organism: Mus musculus/domesticus
Length: 485  
Fragment?: false
•
•
•
•
•
Strain
MGI:7623436 | C57BL/6J-Mpc2<em2Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Allele
Mpc2<em1Smoc> | MGI:7291137
Name: mitochondrial pyruvate carrier 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
•
•
•
•
•
Strain
MGI:6475812 | C57BL/6J-Mpc2<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
•
•
•
•
•
Protein
P63030
Organism: Mus musculus/domesticus
Length: 109  
Fragment?: false
•
•
•
•
•
Protein
Q9D023
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
•
•
•
•
•
Protein
D3Z5S0
Organism: Mus musculus/domesticus
Length: 86  
Fragment?: false
•
•
•
•
•
Protein
Q9D6B6
Organism: Mus musculus/domesticus
Length: 167  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom