Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Kantardzhieva A |
Year: |
2005 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
MPP5 recruits MPP4 to the CRB1 complex in photoreceptors. |
Volume: |
46 |
Issue: |
6 |
Pages: |
2192-201 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aartsen WM |
Year: |
2006 |
Journal: |
Hum Mol Genet |
Title: |
Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse. |
Volume: |
15 |
Issue: |
8 |
Pages: |
1291-302 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang J |
Year: |
2007 |
Journal: |
Hum Mol Genet |
Title: |
Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals. |
Volume: |
16 |
Issue: |
9 |
Pages: |
1017-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aartsen WM |
Year: |
2009 |
Journal: |
Mol Cell Neurosci |
Title: |
PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse. |
Volume: |
41 |
Issue: |
2 |
Pages: |
156-65 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Inagaki H |
Year: |
2002 |
Journal: |
Cell Biol Int |
Title: |
Spatial distribution of mDLG6 mRNA in embryonic and adult mouse brain. |
Volume: |
26 |
Issue: |
7 |
Pages: |
635-40 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5897603 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-05-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5897774 |
Age: |
postnatal month 10 |
|
|
Specimen Label: |
-/- |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5897603 |
Assay Type: |
RT-PCR |
Annotation Date: |
2017-05-19 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1778728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5897774 |
Age: |
postnatal month 10 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7614833 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-03-21 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:3102528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:7614856 |
Age: |
postnatal adult |
|
|
Specimen Label: |
oocyte |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7614833 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160331 |
|
Stage: |
TS01 |
Assay Id: |
MGI:7614856 |
Age: |
embryonic day 0.5 |
|
|
Specimen Label: |
1-cell |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7614833 |
Assay Type: |
RT-PCR |
Annotation Date: |
2024-03-21 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:160362 |
|
Stage: |
TS02 |
Assay Id: |
MGI:7614856 |
Age: |
embryonic day 1.0 |
|
|
Specimen Label: |
2-cell |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7506768 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574428 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7511559 |
Age: |
postnatal month 3 |
|
Note: |
Expression was detected in a continuous band at the outer plexiform layer. |
Specimen Label: |
S6G |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7506768 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3574428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7511559 |
Age: |
postnatal month 3 |
|
Note: |
The mutant immunopositive outer plexiform layer was thinner and showed some disruptions compared with control. |
Specimen Label: |
S6H |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 6-7 |
Image: |
P6/7 |
|
Specimen Label: |
P6/7 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 8-10 |
Image: |
P8/10 |
|
Specimen Label: |
P8/10 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1915528 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal adult |
Image: |
Adult |
|
Specimen Label: |
Adult |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7506768 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3651828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7511559 |
Age: |
postnatal month 3 |
|
Note: |
Expression was present at the synapses of photoreceptors, and at lower levels at the outer limiting membrane. Expression was detected in a continuous band at the outer limiting membrane. |
Specimen Label: |
S6G |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603924 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:3585283 |
Age: |
embryonic day 16.0 |
|
Note: |
Expression was widespread. |
Specimen Label: |
Embryo |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915726 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:3585283 |
Age: |
embryonic day 18.0 |
Image: |
E18 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
E18 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915727 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 0-1 |
Image: |
P0/1 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
P0/1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915727 |
Pattern: |
Not Specified |
Stage: |
TS27 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 2-3 |
Image: |
P2/3 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
P2/3 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 4-5 |
Image: |
P4/5 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
P4/5 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 6-7 |
Image: |
P6/7 |
|
Specimen Label: |
P6/7 |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1915728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 8-10 |
Image: |
P8/10 |
|
Specimen Label: |
P8/10 |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1915728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal adult |
Image: |
Adult |
|
Specimen Label: |
Adult |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1859224 |
Pattern: |
Regionally restricted |
Stage: |
TS24 |
Assay Id: |
MGI:3585283 |
Age: |
embryonic day 16.0 |
Image: |
E16 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
E16 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3521628 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:3585283 |
Age: |
postnatal day 6 |
|
|
Specimen Label: |
CNS |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717120 |
Pattern: |
Regionally restricted |
Stage: |
TS20 |
Assay Id: |
MGI:3585283 |
Age: |
embryonic day 12.0 |
Image: |
E12 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
E12 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3584924 |
Assay Type: |
RNA in situ |
Annotation Date: |
2005-08-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1717122 |
Pattern: |
Regionally restricted |
Stage: |
TS22 |
Assay Id: |
MGI:3585283 |
Age: |
embryonic day 14.0 |
Image: |
E14 |
Note: |
Expression was detected in the outer neuroblastic layer. |
Specimen Label: |
E14 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
van de Pavert SA |
Year: |
2004 |
Journal: |
J Cell Sci |
Title: |
Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure. |
Volume: |
117 |
Issue: |
Pt 18 |
Pages: |
4169-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abe K |
Year: |
2015 |
Journal: |
EMBO J |
Title: |
The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing. |
Volume: |
34 |
Issue: |
11 |
Pages: |
1523-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiao J |
Year: |
2016 |
Journal: |
Exp Neurol |
Title: |
Motor phenotypes and molecular networks associated with germline deficiency of Ciz1. |
Volume: |
283 |
Issue: |
Pt A |
Pages: |
110-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alves CH |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene. |
Volume: |
22 |
Issue: |
1 |
Pages: |
35-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Blackshaw S |
Year: |
2004 |
Journal: |
PLoS Biol |
Title: |
Genomic analysis of mouse retinal development. |
Volume: |
2 |
Issue: |
9 |
Pages: |
E247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
FANTOM2 Data Curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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•
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•
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Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
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•
•
•
•
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Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
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•
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•
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Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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•
•
•
•
•
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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•
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•
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•
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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•
•
•
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•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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•
•
•
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•
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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•
•
•
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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HT Sample |
Organism Name: |
mouse, laboratory |
Sex: |
Female |
Age: |
postnatal week 8-12 |
Stage: |
28 |
Structure . Name: |
bone marrow |
Notes: |
MPP4 (LSK CD34+ CD135+ CD150- CD48+) |
Curation Status: |
Curated |
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•
•
•
•
•
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HT Sample |
Organism Name: |
mouse, laboratory |
Sex: |
Female |
Age: |
postnatal week 8-12 |
Stage: |
28 |
Structure . Name: |
bone marrow |
Notes: |
MPP4 (LSK CD34+ CD135+ CD150- CD48+) |
Curation Status: |
Curated |
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•
•
•
•
•
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HT Sample |
Organism Name: |
mouse, laboratory |
Sex: |
Female |
Age: |
postnatal week 8-12 |
Stage: |
28 |
Structure . Name: |
bone marrow |
Notes: |
MPP4 (LSK CD34+ CD135+ CD150- CD48+) |
Curation Status: |
Curated |
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•
•
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•
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Publication |
First Author: |
Li M |
Year: |
2003 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Developmental and tissue expression patterns of mouse Mpp4 gene. |
Volume: |
307 |
Issue: |
2 |
Pages: |
229-35 |
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•
•
•
•
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Publication |
First Author: |
Stöhr H |
Year: |
2005 |
Journal: |
J Comp Neurol |
Title: |
Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina. |
Volume: |
481 |
Issue: |
1 |
Pages: |
31-41 |
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•
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HT Experiment |
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Experiment Type: |
RNA-Seq |
Study Type: |
Baseline |
Source: |
ArrayExpress |
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•
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Publication |
First Author: |
Lenaerts A |
Year: |
2022 |
Journal: |
J Exp Med |
Title: |
EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors. |
Volume: |
219 |
Issue: |
11 |
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•
•
•
•
•
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Publication |
First Author: |
Klein F |
Year: |
2022 |
Journal: |
Nat Immunol |
Title: |
Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors. |
Volume: |
23 |
Issue: |
4 |
Pages: |
505-517 |
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•
•
•
•
•
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Publication |
First Author: |
Pietras EM |
Year: |
2015 |
Journal: |
Cell Stem Cell |
Title: |
Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions. |
Volume: |
17 |
Issue: |
1 |
Pages: |
35-46 |
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•
•
•
•
•
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Publication |
First Author: |
Förster JR |
Year: |
2009 |
Journal: |
Exp Eye Res |
Title: |
Proteomic analysis of the membrane palmitoylated protein-4 (MPP4)-associated protein complex in the retina. |
Volume: |
88 |
Issue: |
1 |
Pages: |
39-48 |
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•
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Protein Domain |
Type: |
Domain |
Description: |
This entry represents the SH3 domain of MPP4. MPP4, also called Disks Large homologue 6 (DLG6) or amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein (ALS2CR5), is a retina-specific scaffolding protein that plays a role in organizing presynaptic protein complexes in the photoreceptor synapse, where it localizes to the plasma membrane []. It is required in the proper localization of calcium ATPases and for maintenance of calcium homeostasis []. MPP4 belongs to the membrane-associated guanylate kinase (MAGUK) p55 subfamily. The membrane-associated guanylate kinase (MAGUK) p55 subfamily (also known as MPP subfamily) members include the Drosophila Stardust protein and its vertebrate homologues, MPP1-7. They contain the core of three domains characteristic of MAGUK (membrane-associated guanylate kinase) proteins: PDZ, SH3, and guanylate kinase (GuK). In addition, they also contain the Hook (Protein 4.1 Binding) motif in between the SH3 and GuK domains []. MPP2-7 have two additional L27 domains at their N terminus. The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain []. |
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Publication |
First Author: |
Stöhr H |
Year: |
2009 |
Journal: |
J Neurosci |
Title: |
TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals. |
Volume: |
29 |
Issue: |
21 |
Pages: |
6809-18 |
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•
•
•
•
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Publication |
First Author: |
Kantardzhieva A |
Year: |
2006 |
Journal: |
FEBS J |
Title: |
MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane. |
Volume: |
273 |
Issue: |
6 |
Pages: |
1152-65 |
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•
•
•
•
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Publication |
First Author: |
Pilzecker B |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
DNA damage tolerance in hematopoietic stem and progenitor cells in mice. |
Volume: |
114 |
Issue: |
33 |
Pages: |
E6875-E6883 |
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•
•
•
•
•
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Publication |
First Author: |
Zhou C |
Year: |
2022 |
Journal: |
Exp Hematol |
Title: |
Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors. |
Volume: |
112-113 |
|
Pages: |
24-34 |
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•
•
•
•
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Publication |
First Author: |
Stöhr H |
Year: |
2001 |
Journal: |
Genomics |
Title: |
Cloning and characterization of the human retina-specific gene MPP4, a novel member of the p55 subfamily of MAGUK proteins. |
Volume: |
74 |
Issue: |
3 |
Pages: |
377-84 |
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•
•
•
•
•
|
Publication |
First Author: |
te Velthuis AJ |
Year: |
2007 |
Journal: |
BMC Evol Biol |
Title: |
Molecular evolution of the MAGUK family in metazoan genomes. |
Volume: |
7 |
|
Pages: |
129 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
635
 |
Fragment?: |
false |
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•
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