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Search results 1 to 100 out of 102 for Mpp4

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0.044s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Kantardzhieva A
Year: 2005
Journal: Invest Ophthalmol Vis Sci
Title: MPP5 recruits MPP4 to the CRB1 complex in photoreceptors.
Volume: 46
Issue: 6
Pages: 2192-201
Publication
First Author: Aartsen WM
Year: 2006
Journal: Hum Mol Genet
Title: Mpp4 recruits Psd95 and Veli3 towards the photoreceptor synapse.
Volume: 15
Issue: 8
Pages: 1291-302
Publication
First Author: Yang J
Year: 2007
Journal: Hum Mol Genet
Title: Mpp4 is required for proper localization of plasma membrane calcium ATPases and maintenance of calcium homeostasis at the rod photoreceptor synaptic terminals.
Volume: 16
Issue: 9
Pages: 1017-29
Publication
First Author: Aartsen WM
Year: 2009
Journal: Mol Cell Neurosci
Title: PSD95beta regulates plasma membrane Ca2+ pump localization at the photoreceptor synapse.
Volume: 41
Issue: 2
Pages: 156-65
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Inagaki H
Year: 2002
Journal: Cell Biol Int
Title: Spatial distribution of mDLG6 mRNA in embryonic and adult mouse brain.
Volume: 26
Issue: 7
Pages: 635-40
GXD Expression      
Probe: MGI:5897603
Assay Type: RT-PCR
Annotation Date: 2017-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5897774
Age: postnatal month 10
Specimen Label: -/-
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5897603
Assay Type: RT-PCR
Annotation Date: 2017-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:5897774
Age: postnatal month 10
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7614833
Assay Type: RT-PCR
Annotation Date: 2024-03-21
Strength: Absent
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:7614856
Age: postnatal adult
Specimen Label: oocyte
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:7614833
Assay Type: RT-PCR
Annotation Date: 2024-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Stage: TS01
Assay Id: MGI:7614856
Age: embryonic day 0.5
Specimen Label: 1-cell
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7614833
Assay Type: RT-PCR
Annotation Date: 2024-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:7614856
Age: embryonic day 1.0
Specimen Label: 2-cell
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7506768
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7511559
Age: postnatal month 3
Note: Expression was detected in a continuous band at the outer plexiform layer.
Specimen Label: S6G
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7506768
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3574428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7511559
Age: postnatal month 3
Note: The mutant immunopositive outer plexiform layer was thinner and showed some disruptions compared with control.
Specimen Label: S6H
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:7506768
Assay Type: Immunohistochemistry
Annotation Date: 2023-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3651828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7511559
Age: postnatal month 3
Note: Expression was present at the synapses of photoreceptors, and at lower levels at the outer limiting membrane. Expression was detected in a continuous band at the outer limiting membrane.
Specimen Label: S6G
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:3585283
Age: embryonic day 16.0
Note: Expression was widespread.
Specimen Label: Embryo
Detected: true
Specimen Num: 12
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:3585283
Age: embryonic day 18.0
Image: E18
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E18
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585283
Age: postnatal day 0-1
Image: P0/1
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P0/1
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3585283
Age: postnatal day 2-3
Image: P2/3
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P2/3
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal day 4-5
Image: P4/5
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: P4/5
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal day 6-7
Image: P6/7
Specimen Label: P6/7
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal day 8-10
Image: P8/10
Specimen Label: P8/10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Male
Emaps: EMAPS:1915728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal adult
Image: Adult
Specimen Label: Adult
Detected: true
Specimen Num: 10
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1859224
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:3585283
Age: embryonic day 16.0
Image: E16
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E16
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3585283
Age: postnatal day 6
Specimen Label: CNS
Detected: true
Specimen Num: 11
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717120
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:3585283
Age: embryonic day 12.0
Image: E12
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E12
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:3584924
Assay Type: RNA in situ
Annotation Date: 2005-08-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1717122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:3585283
Age: embryonic day 14.0
Image: E14
Note: Expression was detected in the outer neuroblastic layer.
Specimen Label: E14
Detected: true
Specimen Num: 2
Publication
First Author: van de Pavert SA
Year: 2004
Journal: J Cell Sci
Title: Crumbs homologue 1 is required for maintenance of photoreceptor cell polarization and adhesion during light exposure.
Volume: 117
Issue: Pt 18
Pages: 4169-77
Publication
First Author: Abe K
Year: 2015
Journal: EMBO J
Title: The first murine zygotic transcription is promiscuous and uncoupled from splicing and 3' processing.
Volume: 34
Issue: 11
Pages: 1523-37
Publication
First Author: Xiao J
Year: 2016
Journal: Exp Neurol
Title: Motor phenotypes and molecular networks associated with germline deficiency of Ciz1.
Volume: 283
Issue: Pt A
Pages: 110-20
Publication
First Author: Alves CH
Year: 2013
Journal: Hum Mol Genet
Title: Loss of CRB2 in the mouse retina mimics human retinitis pigmentosa due to mutations in the CRB1 gene.
Volume: 22
Issue: 1
Pages: 35-50
Publication
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
HT Sample
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 8-12
Stage: 28
Structure . Name: bone marrow
Notes: MPP4 (LSK CD34+ CD135+ CD150- CD48+)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 8-12
Stage: 28
Structure . Name: bone marrow
Notes: MPP4 (LSK CD34+ CD135+ CD150- CD48+)
Curation Status: Curated
HT Sample
Organism Name: mouse, laboratory
Sex: Female
Age: postnatal week 8-12
Stage: 28
Structure . Name: bone marrow
Notes: MPP4 (LSK CD34+ CD135+ CD150- CD48+)
Curation Status: Curated
Publication
First Author: Li M
Year: 2003
Journal: Biochem Biophys Res Commun
Title: Developmental and tissue expression patterns of mouse Mpp4 gene.
Volume: 307
Issue: 2
Pages: 229-35
Publication
First Author: Stöhr H
Year: 2005
Journal: J Comp Neurol
Title: Membrane-associated guanylate kinase proteins MPP4 and MPP5 associate with Veli3 at distinct intercellular junctions of the neurosensory retina.
Volume: 481
Issue: 1
Pages: 31-41
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: ArrayExpress
Publication
First Author: Klein F
Year: 2022
Journal: Nat Immunol
Title: Dntt expression reveals developmental hierarchy and lineage specification of hematopoietic progenitors.
Volume: 23
Issue: 4
Pages: 505-517
Publication  
First Author: Lenaerts A
Year: 2022
Journal: J Exp Med
Title: EBF1 primes B-lymphoid enhancers and limits the myeloid bias in murine multipotent progenitors.
Volume: 219
Issue: 11
Publication
First Author: Pietras EM
Year: 2015
Journal: Cell Stem Cell
Title: Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions.
Volume: 17
Issue: 1
Pages: 35-46
Publication
First Author: Förster JR
Year: 2009
Journal: Exp Eye Res
Title: Proteomic analysis of the membrane palmitoylated protein-4 (MPP4)-associated protein complex in the retina.
Volume: 88
Issue: 1
Pages: 39-48
Protein Domain
Type: Domain
Description: This entry represents the SH3 domain of MPP4. MPP4, also called Disks Large homologue 6 (DLG6) or amyotrophic lateral sclerosis 2 chromosomal region candidate gene 5 protein (ALS2CR5), is a retina-specific scaffolding protein that plays a role in organizing presynaptic protein complexes in the photoreceptor synapse, where it localizes to the plasma membrane []. It is required in the proper localization of calcium ATPases and for maintenance of calcium homeostasis []. MPP4 belongs to the membrane-associated guanylate kinase (MAGUK) p55 subfamily. The membrane-associated guanylate kinase (MAGUK) p55 subfamily (also known as MPP subfamily) members include the Drosophila Stardust protein and its vertebrate homologues, MPP1-7. They contain the core of three domains characteristic of MAGUK (membrane-associated guanylate kinase) proteins: PDZ, SH3, and guanylate kinase (GuK). In addition, they also contain the Hook (Protein 4.1 Binding) motif in between the SH3 and GuK domains []. MPP2-7 have two additional L27 domains at their N terminus. The GuK domain in MAGUK proteins is enzymatically inactive; instead, the domain mediates protein-protein interactions and associates intramolecularly with the SH3 domain [].
Publication
First Author: Stöhr H
Year: 2009
Journal: J Neurosci
Title: TMEM16B, a novel protein with calcium-dependent chloride channel activity, associates with a presynaptic protein complex in photoreceptor terminals.
Volume: 29
Issue: 21
Pages: 6809-18
Publication
First Author: Kantardzhieva A
Year: 2006
Journal: FEBS J
Title: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane.
Volume: 273
Issue: 6
Pages: 1152-65
Publication
First Author: Pilzecker B
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: DNA damage tolerance in hematopoietic stem and progenitor cells in mice.
Volume: 114
Issue: 33
Pages: E6875-E6883
Publication  
First Author: Zhou C
Year: 2022
Journal: Exp Hematol
Title: Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors.
Volume: 112-113
Pages: 24-34
Publication
First Author: Stöhr H
Year: 2001
Journal: Genomics
Title: Cloning and characterization of the human retina-specific gene MPP4, a novel member of the p55 subfamily of MAGUK proteins.
Volume: 74
Issue: 3
Pages: 377-84
Publication  
First Author: te Velthuis AJ
Year: 2007
Journal: BMC Evol Biol
Title: Molecular evolution of the MAGUK family in metazoan genomes.
Volume: 7
Pages: 129
Protein
Organism: Mus musculus/domesticus
Length: 635  
Fragment?: false