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Search results 1 to 100 out of 177 for Mre11a

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Type Details Score
Gene
406637 | mre11a
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1100512 | Mre11a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29973640 | J:268252
First Author: Hartlerode AJ
Year: 2018
Journal: Sci Rep
Title: Reversible mislocalization of a disease-associated MRE11 splice variant product.
Volume: 8
Issue: 1
Pages: 10121
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Publication
21826105 | J:184053
First Author: Yu Z
Year: 2012
Journal: Cell Res
Title: The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.
Volume: 22
Issue: 2
Pages: 305-20
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Publication
35153719 | J:326998
 
First Author: Ding M
Year: 2021
Journal: Front Aging Neurosci
Title: The Essential DNA Damage Response Complex MRN Is Dispensable for the Survival and Function of Purkinje Neurons.
Volume: 13
Pages: 786199
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Publication
19667076 | J:153902
First Author: Attwooll CL
Year: 2009
Journal: Mol Cell Biol
Title: The mre11 complex and the response to dysfunctional telomeres.
Volume: 29
Issue: 20
Pages: 5540-51
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Publication
14690604 | J:87088
First Author: Theunissen JW
Year: 2003
Journal: Mol Cell
Title: Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice.
Volume: 12
Issue: 6
Pages: 1511-23
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Publication
17291760 | J:120745
First Author: Cherry SM
Year: 2007
Journal: Curr Biol
Title: The Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosis.
Volume: 17
Issue: 4
Pages: 373-8
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Publication
28362262 | J:258212
   
First Author: Morales AJ
Year: 2017
Journal: Elife
Title: A type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.
Volume: 6
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Publication
24120666 | J:205983
First Author: Gupta GP
Year: 2013
Journal: Mol Cell
Title: The Mre11 complex suppresses oncogene-driven breast tumorigenesis and metastasis.
Volume: 52
Issue: 3
Pages: 353-65
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Publication
23912341 | J:203129
First Author: Regal JA
Year: 2013
Journal: Hum Mol Genet
Title: Disease-associated MRE11 mutants impact ATM/ATR DNA damage signaling by distinct mechanisms.
Volume: 22
Issue: 25
Pages: 5146-59
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Publication
18854157 | J:147247
First Author: Buis J
Year: 2008
Journal: Cell
Title: Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation.
Volume: 135
Issue: 1
Pages: 85-96
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Publication
19633670 | J:272543
First Author: Dinkelmann M
Year: 2009
Journal: Nat Struct Mol Biol
Title: Multiple functions of MRN in end-joining pathways during isotype class switching.
Volume: 16
Issue: 8
Pages: 808-13
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Publication
19015239 | J:144749
First Author: Stracker TH
Year: 2009
Journal: Mol Cell Biol
Title: Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability.
Volume: 29
Issue: 2
Pages: 503-14
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Publication
28819025 | J:245675
First Author: Spehalski E
Year: 2017
Journal: Cancer Res
Title: MRE11 Promotes Tumorigenesis by Facilitating Resistance to Oncogene-Induced Replication Stress.
Volume: 77
Issue: 19
Pages: 5327-5338
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Protein Coding Gene
MGP_CAROLIEiJ_G0031788 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034356 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034262 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034328 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1100512 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034850 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033366 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034012 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034255 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034158 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034869 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033072 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014664 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032908 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9224597 | J:42675
First Author: Xiao Y
Year: 1997
Journal: Nucleic Acids Res
Title: Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells.
Volume: 25
Issue: 15
Pages: 2985-91
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Publication
19075003 | J:145743
First Author: Vissinga CS
Year: 2009
Journal: Mol Cell Biol
Title: Nuclear export of NBN is required for normal cellular responses to radiation.
Volume: 29
Issue: 4
Pages: 1000-6
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Publication
27708105 | J:235861
First Author: Kanakkanthara A
Year: 2016
Journal: Science
Title: Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation.
Volume: 353
Issue: 6307
Pages: 1549-1552
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GXD Expression
GXD Expression
   
Probe: MGI:7412813
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691016
Stage: TS16
Assay Id: MGI:7412905
Age: embryonic day 10.0
Image: 2
Specimen Label: E10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7412813
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754426
Stage: TS26
Assay Id: MGI:7412905
Age: embryonic day 18.0
Image: 2
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7412813
Assay Type: RT-PCR
Annotation Date: 2022-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7412905
Age: postnatal month 2
Image: 2
Specimen Label: 2 months
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7448599
Assay Type: Western blot
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Stage: TS20
Assay Id: MGI:7448705
Age: embryonic day 12.5
Image: 2
Specimen Label: CNS-ctr E12.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7448599
Assay Type: Western blot
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Stage: TS23
Assay Id: MGI:7448705
Age: embryonic day 15.5
Image: 2
Specimen Label: CNS-ctr E15.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7448599
Assay Type: Western blot
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7448705
Age: embryonic day 18.5
Image: 2
Specimen Label: CNS-ctr E18.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7448599
Assay Type: Western blot
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284220
Stage: TS20
Assay Id: MGI:7448705
Age: embryonic day 12.5
Image: 2
Specimen Label: CNS-del E12.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7448599
Assay Type: Western blot
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284223
Stage: TS23
Assay Id: MGI:7448705
Age: embryonic day 15.5
Image: 2
Specimen Label: CNS-del E15.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7448599
Assay Type: Western blot
Annotation Date: 2023-03-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284226
Stage: TS26
Assay Id: MGI:7448705
Age: embryonic day 18.5
Image: 2
Specimen Label: CNS-del E18.5
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:7464280
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-20
Strength: Present
Sex: Male
Emaps: EMAPS:3148428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7464322
Age: postnatal day 18
Image: 7Bj
Note: Expression in XY body in pachytene spermatocytes.
Specimen Label: 7Bj
Detected: true
Specimen Num: 1
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Publication
- | J:65962
   
First Author: Oshiumi H
Year: 1996
Journal: GenBank Submission
Title: Mus musculus putative endo/exonuclease MmMre11b (MmMRE11) mRNA, alternative splicing product, complete cds
Pages: U60318
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Publication
- | J:65963
   
First Author: Oshiumi H
Year: 1996
Journal: GenBank Submission
Title: Mus musculus putative endo/exonuclease MmMre11a (MmMRE11) mRNA, complete cds
Pages: U58987
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Publication
19171781 | J:144172
First Author: Shull ER
Year: 2009
Journal: Genes Dev
Title: Differential DNA damage signaling accounts for distinct neural apoptotic responses in ATLD and NBS.
Volume: 23
Issue: 2
Pages: 171-80
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Publication
20086180 | J:156862
First Author: Rotolo JA
Year: 2010
Journal: Cancer Res
Title: Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.
Volume: 70
Issue: 3
Pages: 957-67
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Publication
18614044 | J:138550
First Author: Stracker TH
Year: 2008
Journal: Mol Cell
Title: Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.
Volume: 31
Issue: 1
Pages: 21-32
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Publication
16357220 | J:103922
First Author: Morales M
Year: 2005
Journal: Genes Dev
Title: The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.
Volume: 19
Issue: 24
Pages: 3043-54
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Publication
25768017 | J:224234
First Author: Pacheco S
Year: 2015
Journal: PLoS Genet
Title: The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes.
Volume: 11
Issue: 3
Pages: e1005017
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Publication
18381424 | J:133303
First Author: Morales M
Year: 2008
Journal: Cancer Res
Title: DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesions.
Volume: 68
Issue: 7
Pages: 2186-93
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Publication
19221393 | J:146799
First Author: Helmink BA
Year: 2009
Journal: J Exp Med
Title: MRN complex function in the repair of chromosomal Rag-mediated DNA double-strand breaks.
Volume: 206
Issue: 3
Pages: 669-79
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Publication
31285322 | J:277750
First Author: Kim JH
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Nbn-Mre11 interaction is required for tumor suppression and genomic integrity.
Volume: 116
Issue: 30
Pages: 15178-15183
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Publication
23388631 | J:195213
First Author: Kondo T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking.
Volume: 110
Issue: 8
Pages: 2969-74
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Publication
28076792 | J:251434
First Author: Kim JH
Year: 2017
Journal: Cell Rep
Title: The Mre11-Nbs1 Interface Is Essential for Viability and Tumor Suppression.
Volume: 18
Issue: 2
Pages: 496-507
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Publication
27814490 | J:252209
First Author: Hoa NN
Year: 2016
Journal: Mol Cell
Title: Mre11 Is Essential for the Removal of Lethal Topoisomerase 2 Covalent Cleavage Complexes.
Volume: 64
Issue: 3
Pages: 580-592
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Publication
19633651 | J:151777
First Author: Deng Y
Year: 2009
Journal: Nature
Title: Multiple roles for MRE11 at uncapped telomeres.
Volume: 460
Issue: 7257
Pages: 914-8
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Publication
26512707 | J:320151
First Author: Lavin MF
Year: 2015
Journal: Biomolecules
Title: ATM-Dependent Phosphorylation of All Three Members of the MRN Complex: From Sensor to Adaptor.
Volume: 5
Issue: 4
Pages: 2877-902
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Publication
23444137 | J:228107
First Author: Chang FT
Year: 2013
Journal: Nucleic Acids Res
Title: PML bodies provide an important platform for the maintenance of telomeric chromatin integrity in embryonic stem cells.
Volume: 41
Issue: 8
Pages: 4447-58
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Publication
12687013 | J:84394
First Author: Franchitto A
Year: 2003
Journal: Oncogene
Title: The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase.
Volume: 22
Issue: 14
Pages: 2110-20
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Publication
21677273 | J:178657
First Author: Dmitrieva NI
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: Mre11 is expressed in mammalian mitochondria where it binds to mitochondrial DNA.
Volume: 301
Issue: 3
Pages: R632-40
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Publication
31123184 | J:277567
First Author: Chen BR
Year: 2019
Journal: J Cell Biol
Title: XLF and H2AX function in series to promote replication fork stability.
Volume: 218
Issue: 7
Pages: 2113-2123
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Publication
36563124 | J:344817
First Author: Liu W
Year: 2023
Journal: Adv Sci (Weinh)
Title: RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.
Volume: 10
Issue: 5
Pages: e2203884
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Publication
24793032 | J:212924
First Author: Katyal S
Year: 2014
Journal: Nat Neurosci
Title: Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes.
Volume: 17
Issue: 6
Pages: 813-21
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Publication
12208847 | J:78820
First Author: Bender CF
Year: 2002
Journal: Genes Dev
Title: Cancer predisposition and hematopoietic failure in Rad50(S/S) mice.
Volume: 16
Issue: 17
Pages: 2237-51
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Publication
17429352 | J:129762
First Author: Stracker TH
Year: 2007
Journal: Nature
Title: The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex.
Volume: 447
Issue: 7141
Pages: 218-21
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Publication
19667071 | J:153904
First Author: Dimitrova N
Year: 2009
Journal: Mol Cell Biol
Title: Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2.
Volume: 29
Issue: 20
Pages: 5552-63
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Publication
15734743 | J:99937
First Author: Alt JR
Year: 2005
Journal: J Biol Chem
Title: Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.
Volume: 280
Issue: 19
Pages: 18771-81
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Publication
29709199 | J:320083
 
First Author: Syed A
Year: 2018
Journal: Annu Rev Biochem
Title: The MRE11-RAD50-NBS1 Complex Conducts the Orchestration of Damage Signaling and Outcomes to Stress in DNA Replication and Repair.
Volume: 87
Pages: 263-294
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Publication
18171670 | J:319979
First Author: Chen L
Year: 2008
Journal: J Biol Chem
Title: Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.
Volume: 283
Issue: 12
Pages: 7713-20
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Publication
30657944 | J:319683
First Author: Mohiuddin M
Year: 2019
Journal: Nucleic Acids Res
Title: CtIP-BRCA1 complex and MRE11 maintain replication forks in the presence of chain terminating nucleoside analogs.
Volume: 47
Issue: 6
Pages: 2966-2980
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Publication
26232174 | J:316710
First Author: Inagaki A
Year: 2016
Journal: Chromosoma
Title: Functions of the MRE11 complex in the development and maintenance of oocytes.
Volume: 125
Issue: 1
Pages: 151-62
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Publication
30017584 | J:265834
First Author: Hung PJ
Year: 2018
Journal: Mol Cell
Title: MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
Volume: 71
Issue: 2
Pages: 332-342.e8
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Publication
21852425 | J:185876
First Author: Bördlein A
Year: 2011
Journal: J Cell Sci
Title: SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis.
Volume: 124
Issue: Pt 18
Pages: 3137-48
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Publication
28115467 | J:238694
First Author: Gong Y
Year: 2017
Journal: Genes Dev
Title: PHF11 promotes DSB resection, ATR signaling, and HR.
Volume: 31
Issue: 1
Pages: 46-58
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Publication
15364958 | J:92518
First Author: Sengupta S
Year: 2004
Journal: J Cell Biol
Title: Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.
Volume: 166
Issue: 6
Pages: 801-13
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Publication
33524014 | J:305161
First Author: Dar AA
Year: 2021
Journal: PLoS Biol
Title: The E3 ubiquitin ligase Cul4b promotes CD4+ T cell expansion by aiding the repair of damaged DNA.
Volume: 19
Issue: 2
Pages: e3001041
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Publication
27171262 | J:316683
 
First Author: Huh MS
Year: 2016
Journal: Cell Death Dis
Title: Stalled replication forks within heterochromatin require ATRX for protection.
Volume: 7
Pages: e2220
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Publication
22369660 | J:320080
First Author: Wang B
Year: 2012
Journal: Cell Biosci
Title: BRCA1 tumor suppressor network: focusing on its tail.
Volume: 2
Issue: 1
Pages: 6
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Publication
17500065 | J:123598
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
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Publication
19124014 | J:146199
First Author: Barrionuevo F
Year: 2009
Journal: Dev Biol
Title: Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8.
Volume: 327
Issue: 2
Pages: 301-12
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Publication
19876815 | J:159668
First Author: Kim GJ
Year: 2010
Journal: Int J Dev Biol
Title: Dicer is required for Sertoli cell function and survival.
Volume: 54
Issue: 5
Pages: 867-75
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Publication
35920200 | J:329968
First Author: Kazi S
Year: 2022
Journal: FASEB J
Title: MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice.
Volume: 36
Issue: 9
Pages: e22479
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Publication
22212482 | J:316150
First Author: Li R
Year: 2012
Journal: Cell Res
Title: A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.
Volume: 22
Issue: 5
Pages: 859-72
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Publication
34746147 | J:314268
 
First Author: Akagawa R
Year: 2021
Journal: Front Cell Dev Biol
Title: Alternative Functions of Cell Cycle-Related and DNA Repair Proteins in Post-mitotic Neurons.
Volume: 9
Pages: 753175
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
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First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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First Author: Mouse Genome Informatics Scientific Curators
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Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
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First Author: GemPharmatech
Year: 2020
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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14610273 | J:86696
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Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
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Pages: 14109-14
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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