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Search results 1 to 89 out of 89 for Mrfap1

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: MRFAP1 (MORF4 family-associated protein 1) and its interaction partner MORF4L1 (or MRG15) are target proteins of the NEDD8-cullin pathway, which plays an important role in the degradation of cell cycle regulators and transcriptional control networks. It has been suggest that MRFAP1 competes with MRGBP for binding to MORF4L1, thereby regulating MORF4L1 function in chromatin modification [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Larance M
Year: 2012
Journal: Mol Cell Proteomics
Title: Characterization of MRFAP1 turnover and interactions downstream of the NEDD8 pathway.
Volume: 11
Issue: 3
Pages: M111.014407
Protein
Organism: Mus musculus/domesticus
Length: 125  
Fragment?: false
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Brain +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Kidney +/+
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Liver +/+
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Lung +/+
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Testis +/+
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Brain +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Brain -/-
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Kidney +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Kidney -/-
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Liver +/-
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Liver -/-
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Lung +/-
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Lung -/-
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Testis +/-
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:3513674
Assay Type: Northern blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3513683
Age: postnatal
Specimen Label: Testis -/-
Detected: false
Specimen Num: 15
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: +/+
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: +/-
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: +/-
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: +/-
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:3513680
Assay Type: Western blot
Annotation Date: 2005-01-11
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3513770
Age: postnatal
Specimen Label: -/-
Detected: false
Specimen Num: 9
Publication
First Author: Tominaga K
Year: 2004
Journal: Mol Cell Biol
Title: PAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in mice.
Volume: 24
Issue: 19
Pages: 8366-73
Publication
First Author: Thuret S
Year: 2004
Journal: Mol Cell Neurosci
Title: Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.
Volume: 25
Issue: 3
Pages: 394-405
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Yochum GS
Year: 2002
Journal: Mol Cell Biol
Title: Role for the mortality factors MORF4, MRGX, and MRG15 in transcriptional repression via associations with Pf1, mSin3A, and Transducin-Like Enhancer of Split.
Volume: 22
Issue: 22
Pages: 7868-76
Publication
First Author: Tominaga K
Year: 2003
Journal: J Biol Chem
Title: MRGX is a novel transcriptional regulator that exhibits activation or repression of the B-myb promoter in a cell type-dependent manner.
Volume: 278
Issue: 49
Pages: 49618-24
Protein Domain
Type: Family
Description: Mortality factor 4-like protein 2 (MORF4L2 or MRGX) is a component of the NuA4 histone acetyltransferase complex []and the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones []. MRGX interacts with MRFAP1 and RB1 and represses the B-myb promoter in EJ cells but activates it in HeLa cells []. MRGX contains an MRG domain.The NuA4 histone acetyltransferase complex (also known as the TRRAP/TIP60-containing histone acetyltransferase complex) acetylates nucleosomal histones H4 and H2A thereby activating selected genes for transcription and is a a key regulator of transcription, cellular response to DNA damage and cell cycle control []. In yeast, where the complex was first identified, NuA4 consists of at least ACT1, ARP4, YAF9, VID21, SWC4, EAF3, EAF5, EAF6, EAF7, EPL1, ESA1, TRA1 and YNG2 []. In humans, the complex is composed of the histone acetyltransferase KAT5 (also known as TIP60) plus the subunits EP400, TRRAP/PAF400, BRD8/SMAP, EPC1, MAP1/DNMAP1, RUVBL1/TIP49, RUVBL2, ING3, actin, ACTL6A/BAF53A, MORF4L1/MRG15, MORF4L2/MRGX, MRGBP, YEATS4/GAS41, VPS72/YL1 and MEAF6 [].
Protein
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 305  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 288  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 204  
Fragment?: true
Publication
First Author: Cai Y
Year: 2003
Journal: J Biol Chem
Title: Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex.
Volume: 278
Issue: 44
Pages: 42733-6
Publication
First Author: Kobor MS
Year: 2004
Journal: PLoS Biol
Title: A protein complex containing the conserved Swi2/Snf2-related ATPase Swr1p deposits histone variant H2A.Z into euchromatin.
Volume: 2
Issue: 5
Pages: E131
Publication
First Author: Doyon Y
Year: 2004
Journal: Curr Opin Genet Dev
Title: The highly conserved and multifunctional NuA4 HAT complex.
Volume: 14
Issue: 2
Pages: 147-54