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Search results 1 to 64 out of 64 for Mrgpra3

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Hits by Strain

Hits by Category

Type Details Score
Protein Coding Gene
MGI:2684085 | Mrgpra3
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:7388606
Assay Type: RNA in situ
Annotation Date: 2022-12-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7388628
Age: postnatal day 30
Image: 4B Mrgpra3 Control
Specimen Label: 4B Mrgpra3 Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7388606
Assay Type: RNA in situ
Annotation Date: 2022-12-02
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3667828
Stage: TS28
Assay Id: MGI:7388628
Age: postnatal day 30
Image: 4B Mrgpra3 Tlx3 CKO
Note: Expression eliminated.
Specimen Label: 4B Mrgpra3 Tlx3 CKO
Detected: false
Specimen Num: 2
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Publication
33727332 | J:311626
First Author: Grundy L
Year: 2021
Journal: J Neurosci
Title: Activation of MrgprA3 and MrgprC11 on Bladder-Innervating Afferents Induces Peripheral and Central Hypersensitivity to Bladder Distension.
Volume: 41
Issue: 17
Pages: 3900-3916
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Publication
23263443 | J:197482
First Author: Han L
Year: 2013
Journal: Nat Neurosci
Title: A subpopulation of nociceptors specifically linked to itch.
Volume: 16
Issue: 2
Pages: 174-82
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Publication
25834056 | J:221586
First Author: Lou S
Year: 2015
Journal: J Neurosci
Title: Incoherent feed-forward regulatory loops control segregation of C-mechanoreceptors, nociceptors, and pruriceptors.
Volume: 35
Issue: 13
Pages: 5317-29
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Publication
24549959 | J:346363
First Author: Qu L
Year: 2014
Journal: Brain
Title: Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain.
Volume: 137
Issue: Pt 4
Pages: 1039-50
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Publication
20004959 | J:157470
First Author: Liu Q
Year: 2009
Journal: Cell
Title: Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.
Volume: 139
Issue: 7
Pages: 1353-65
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Publication
23000623 | J:192750
 
First Author: Akiyama T
Year: 2012
Journal: Neuroscience
Title: Cross-sensitization of histamine-independent itch in mouse primary sensory neurons.
Volume: 226
Pages: 305-12
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Protein Coding Gene
MGI_C57BL6J_2684085 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0032768 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0032785 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
11551509 | J:71586
First Author: Dong X
Year: 2001
Journal: Cell
Title: A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons.
Volume: 106
Issue: 5
Pages: 619-32
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Publication
12397184 | J:87341
First Author: Han SK
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway.
Volume: 99
Issue: 23
Pages: 14740-5
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Publication
12909716 | J:87340
First Author: Zylka MJ
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family.
Volume: 100
Issue: 17
Pages: 10043-8
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
17553423 | J:126484
First Author: Luo W
Year: 2007
Journal: Neuron
Title: A hierarchical NGF signaling cascade controls Ret-dependent and Ret-independent events during development of nonpeptidergic DRG neurons.
Volume: 54
Issue: 5
Pages: 739-54
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Publication
29045838 | J:254788
First Author: Chen Z
Year: 2017
Journal: Cell Rep
Title: p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling.
Volume: 21
Issue: 3
Pages: 707-720
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Publication
28476948 | J:242690
First Author: Qi L
Year: 2017
Journal: J Neurosci
Title: Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1.
Volume: 37
Issue: 22
Pages: 5549-5561
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Publication
35875660 | J:326957
 
First Author: Cao Z
Year: 2022
Journal: Front Mol Neurosci
Title: Meis1 Regulates Nociceptor Development and Behavioral Response to Tactile Stimuli.
Volume: 15
Pages: 901466
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Publication
22787056 | J:186470
First Author: Lopes C
Year: 2012
Journal: J Neurosci
Title: Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors.
Volume: 32
Issue: 28
Pages: 9706-15
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
26874069 | J:230862
 
First Author: Tang M
Year: 2016
Journal: Brain Res
Title: Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons.
Volume: 1636
Pages: 161-71
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GXD Expression
GXD Expression
 
Probe: MGI:6694323
Assay Type: RNA in situ
Annotation Date: 2021-04-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2516728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6694327
Age: postnatal adult
Image: 7A
Specimen Label: 7A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6694323
Assay Type: RNA in situ
Annotation Date: 2021-04-23
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2516728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6694327
Age: postnatal adult
Image: 7D
Note: Authors report over 50% of MrgA-expressing neurons were lost.
Specimen Label: 7D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7471454
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7481282
Age: postnatal day 14
Note: Expression in ~10 neurons/section.
Specimen Label: 6M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7471454
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1666828
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:7481282
Age: postnatal day 14
Note: Expression greatly reduced compared to control. Expression in ~2 neurons/section.
Specimen Label: 6N
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7471454
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666827
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:7481282
Age: postnatal day 0
Note: Expression in ~16 neurons/section.
Specimen Label: 7C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7471454
Assay Type: RNA in situ
Annotation Date: 2023-05-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1666827
Stage: TS27
Assay Id: MGI:7481282
Age: postnatal day 0
Note: ression completely eliminated.
Specimen Label: 7D
Detected: false
Specimen Num: 4
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
32298640 | J:296179
First Author: Sharif B
Year: 2020
Journal: Neuron
Title: Differential Coding of Itch and Pain by a Subpopulation of Primary Afferent Neurons.
Volume: 106
Issue: 6
Pages: 940-951.e4
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Publication
35704588 | J:326779
First Author: Tseng PY
Year: 2022
Journal: Sci Adv
Title: GPR15L is an epithelial inflammation-derived pruritogen.
Volume: 8
Issue: 24
Pages: eabm7342
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Allele
Tg(Mrgpra3-GFP/cre)#Xzd | MGI:5506535
Name: transgene insertion, Xinzhong Dong
Allele Type: Transgenic
Attribute String: Recombinase
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Publication
29988128 | J:268042
First Author: Huang CC
Year: 2018
Journal: Nat Med
Title: Anatomical and functional dichotomy of ocular itch and pain.
Volume: 24
Issue: 8
Pages: 1268-1276
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Publication
21460831 | J:172290
First Author: Wilson SR
Year: 2011
Journal: Nat Neurosci
Title: TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch.
Volume: 14
Issue: 5
Pages: 595-602
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Trpv1/Trpv1 Tg(Mrgpra3-GFP/cre)#Xzd/?
Background: involves: 129P2/OlaHsd * 129X1/SvJ
Zygosity: cn
Has Mutant Allele: true
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Publication
31536477 | J:287663
 
First Author: Castro J
Year: 2019
Journal: JCI Insight
Title: Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity.
Volume: 4
Issue: 20
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Publication
34480893 | J:316388
     
First Author: Tseng PY
Year: 2021
Journal: J Invest Dermatol
Title: Specific β-Defensins Stimulate Pruritus through Activation of Sensory Neurons.
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Publication
30395542 | J:270913
First Author: Salvatierra J
Year: 2018
Journal: J Clin Invest
Title: A disease mutation reveals a role for NaV1.9 in acute itch.
Volume: 128
Issue: 12
Pages: 5434-5447
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Mrgpra3-GFP/cre)#Xzd/?
Background: involves: C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Publication
36693373 | J:337518
First Author: Elias LJ
Year: 2023
Journal: Cell
Title: Touch neurons underlying dopaminergic pleasurable touch and sexual receptivity.
Volume: 186
Issue: 3
Pages: 577-590.e16
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Publication
30408082 | J:267833
First Author: Wu P
Year: 2018
Journal: PLoS One
Title: Characterization of sensory neuronal subtypes innervating mouse tongue.
Volume: 13
Issue: 11
Pages: e0207069
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Publication
30657454 | J:277452
   
First Author: Meixiong J
Year: 2019
Journal: Elife
Title: Identification of a bilirubin receptor that may mediate a component of cholestatic itch.
Volume: 8
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Publication
34986325 | J:325013
First Author: Cui L
Year: 2022
Journal: Neuron
Title: Glutamate in primary afferents is required for itch transmission.
Volume: 110
Issue: 5
Pages: 809-823.e5
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Publication
33876765 | J:304844
 
First Author: Steele HR
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: MrgprC11+ sensory neurons mediate glabrous skin itch.
Volume: 118
Issue: 15
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Publication
29864146 | J:262850
First Author: Patil MJ
Year: 2018
Journal: PLoS One
Title: Characteristics of sensory neuronal groups in CGRP-cre-ER reporter mice: Comparison to Nav1.8-cre, TRPV1-cre and TRPV1-GFP mouse lines.
Volume: 13
Issue: 6
Pages: e0198601
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Publication
31103358 | J:278487
First Author: Pagani M
Year: 2019
Journal: Neuron
Title: How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch.
Volume: 103
Issue: 1
Pages: 102-117.e5
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Publication
30655357 | J:273606
First Author: Albisetti GW
Year: 2019
Journal: J Neurosci
Title: Dorsal Horn Gastrin-Releasing Peptide Expressing Neurons Transmit Spinal Itch But Not Pain Signals.
Volume: 39
Issue: 12
Pages: 2238-2250
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Publication
31914619 | J:299493
First Author: Patil MJ
Year: 2020
Journal: FASEB J
Title: Sensitization of small-diameter sensory neurons is controlled by TRPV1 and TRPA1 association.
Volume: 34
Issue: 1
Pages: 287-302
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Publication
33765440 | J:305469
First Author: Zhang S
Year: 2021
Journal: Cell
Title: Nonpeptidergic neurons suppress mast cells via glutamate to maintain skin homeostasis.
Volume: 184
Issue: 8
Pages: 2151-2166.e16
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Publication
33091423 | J:305032
First Author: Xing Y
Year: 2021
Journal: J Invest Dermatol
Title: Visualizing the Itch-Sensing Skin Arbors.
Volume: 141
Issue: 5
Pages: 1308-1316
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Publication
30104684 | J:267282
First Author: Ralvenius WT
Year: 2018
Journal: Nat Commun
Title: Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors.
Volume: 9
Issue: 1
Pages: 3230
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Publication
28231466 | J:249930
First Author: Sun S
Year: 2017
Journal: Neuron
Title: Leaky Gate Model: Intensity-Dependent Coding of Pain and Itch in the Spinal Cord.
Volume: 93
Issue: 4
Pages: 840-853.e5
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Publication
37541195 | J:341426
First Author: Wolfson RL
Year: 2023
Journal: Cell
Title: DRG afferents that mediate physiologic and pathologic mechanosensation from the distal colon.
Volume: 186
Issue: 16
Pages: 3368-3385.e18
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