| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Membrane-spanning 4-domains subfamily A member 7 (MS4A7), also known as CD20/FcepsilonRIbeta family member 4 (CFFM4), is associated with mature cellular function in the monocytic lineage and, like CD20 and FcepsilonRIbeta, it may be a component of a receptor complex involved in signal transduction []. |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
267
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
267
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
234
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
102
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
234
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
130
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
234
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
234
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
215
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Gingras MC |
| Year: |
2001 |
| Journal: |
Immunogenetics |
| Title: |
CFFM4: a new member of the CD20/FcepsilonRIbeta family. |
| Volume: |
53 |
| Issue: |
6 |
| Pages: |
468-76 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Zhou L |
| Year: |
2024 |
| Journal: |
Sci Transl Med |
| Title: |
Hepatic danger signaling triggers TREM2(+) macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation. |
| Volume: |
16 |
| Issue: |
738 |
| Pages: |
eadk1866 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Srivastava N |
| Year: |
2024 |
| Journal: |
Immunity |
| Title: |
CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8(+) T cells in diabetic autoimmunity. |
|
|
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_01 |
|
| Specimen Label: |
euxassay_012608_01 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_02 |
|
| Specimen Label: |
euxassay_012608_02 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_03 |
|
| Specimen Label: |
euxassay_012608_03 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_04 |
|
| Specimen Label: |
euxassay_012608_04 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_05 |
|
| Specimen Label: |
euxassay_012608_05 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_06 |
|
| Specimen Label: |
euxassay_012608_06 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_07 |
|
| Specimen Label: |
euxassay_012608_07 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_08 |
|
| Specimen Label: |
euxassay_012608_08 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_09 |
|
| Specimen Label: |
euxassay_012608_09 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_10 |
|
| Specimen Label: |
euxassay_012608_10 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_11 |
|
| Specimen Label: |
euxassay_012608_11 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_12 |
|
| Specimen Label: |
euxassay_012608_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_13 |
|
| Specimen Label: |
euxassay_012608_13 |
| Detected: |
true |
| Specimen Num: |
13 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_14 |
|
| Specimen Label: |
euxassay_012608_14 |
| Detected: |
true |
| Specimen Num: |
14 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_15 |
|
| Specimen Label: |
euxassay_012608_15 |
| Detected: |
true |
| Specimen Num: |
15 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_16 |
|
| Specimen Label: |
euxassay_012608_16 |
| Detected: |
true |
| Specimen Num: |
16 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_17 |
|
| Specimen Label: |
euxassay_012608_17 |
| Detected: |
true |
| Specimen Num: |
17 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_18 |
|
| Specimen Label: |
euxassay_012608_18 |
| Detected: |
true |
| Specimen Num: |
18 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_19 |
|
| Specimen Label: |
euxassay_012608_19 |
| Detected: |
true |
| Specimen Num: |
19 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_20 |
|
| Specimen Label: |
euxassay_012608_20 |
| Detected: |
true |
| Specimen Num: |
20 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3596123 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_21 |
|
| Specimen Label: |
euxassay_012608_21 |
| Detected: |
true |
| Specimen Num: |
21 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:4416970 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2010-09-14 |
| Strength: |
Moderate |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:4826463 |
| Age: |
embryonic day 14.5 |
| Image: |
euxassay_012608_12 |
|
| Specimen Label: |
euxassay_012608_12 |
| Detected: |
true |
| Specimen Num: |
12 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Liang Y |
| Year: |
2001 |
| Journal: |
Genomics |
| Title: |
Identification of a CD20-, FcepsilonRIbeta-, and HTm4-related gene family: sixteen new MS4A family members expressed in human and mouse. |
| Volume: |
72 |
| Issue: |
2 |
| Pages: |
119-27 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Hammond TR |
| Year: |
2019 |
| Journal: |
Immunity |
| Title: |
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes. |
| Volume: |
50 |
| Issue: |
1 |
| Pages: |
253-271.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Rosin JM |
| Year: |
2021 |
| Journal: |
Dev Cell |
| Title: |
A subpopulation of embryonic microglia respond to maternal stress and influence nearby neural progenitors. |
| Volume: |
56 |
| Issue: |
9 |
| Pages: |
1326-1345.e6 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lopez-Tello J |
| Year: |
2023 |
| Journal: |
Front Endocrinol (Lausanne) |
| Title: |
Characterization of placental endocrine function and fetal brain development in a mouse model of small for gestational age. |
| Volume: |
14 |
|
| Pages: |
1116770 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Abdallah BM |
| Year: |
2011 |
| Journal: |
J Bone Miner Res |
| Title: |
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. |
| Volume: |
26 |
| Issue: |
7 |
| Pages: |
1457-71 |
|
•
•
•
•
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Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
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2001 |
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LocusLink Collaboration |
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Mouse Genome Informatics Scientific Curators |
| Year: |
2002 |
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Function or Process or Component Unknown following Literature Review |
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| First Author: |
Velocigene |
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2008 |
| Journal: |
MGI Direct Data Submission |
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Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
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Shanghai Model Organisms Center |
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2017 |
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MGI Direct Data Submission |
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Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
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Mouse Genome Informatics Scientific Curators |
| Year: |
2003 |
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MGI Sequence Curation Reference |
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| First Author: |
Mouse Genome Informatics Scientific Curators |
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2002 |
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Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
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Carninci P |
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2005 |
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Science |
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The transcriptional landscape of the mammalian genome. |
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Kawai J |
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2001 |
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Nature |
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Cyagen Biosciences Inc. |
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2002 |
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Nature |
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Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
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The Gene Ontology Consortium |
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2010 |
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Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
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Mouse Genome Informatics Scientific Curators |
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2002 |
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Mouse Genome Informatics Computational Sequence to Gene Associations |
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MGI Genome Annotation Group and UniGene Staff |
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MGI-UniGene Interconnection Effort |
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Annotation inferences using phylogenetic trees |
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Mouse Genome Database and National Center for Biotechnology Information |
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2000 |
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Allen Institute for Brain Science |
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2004 |
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Allen Institute |
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Allen Brain Atlas: mouse riboprobes |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
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2010 |
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Mouse Genome Informatics Group |
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2003 |
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Database Procedure |
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Mouse Genome Informatics Scientific Curators |
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2005 |
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Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Mouse Genome Informatics Scientific Curators |
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2005 |
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Obtaining and loading genome assembly coordinates from NCBI annotations |
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Mouse Genome Informatics Scientific Curators |
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2009 |
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Database Download |
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Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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| Allele |
| Name: |
membrane-spanning 4-domains, subfamily A, member 7; endonuclease-mediated mutation 1, Jiandie D Lin |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Conditional ready |
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| Allele |
| Name: |
membrane-spanning 4-domains, subfamily A, member 7; endonuclease-mediated mutation 1, Xiaoxiao Wan |
| Allele Type: |
Endonuclease-mediated |
| Attribute String: |
Null/knockout |
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