|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 436 for Msh2

<< First    < Previous  |  Next >    Last >>
0.038s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
4436 | MSH2
Type: gene
Organism: human
•
•
•
•
•
Gene
533115 | MSH2
Type: gene
Organism: cattle
•
•
•
•
•
Gene
378799 | MSH2
Type: gene
Organism: chicken
•
•
•
•
•
Gene
406845 | msh2
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
718017 | MSH2
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Gene
100380043 | msh2
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
107973458 | MSH2
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
81709 | Msh2
Type: gene
Organism: rat
•
•
•
•
•
Gene
494002 | MSH2
Type: gene
Organism: dog, domestic
•
•
•
•
•
Protein Domain
IPR032642 | Msh2
Type: Family
Description: This entry represents the DNA mismatch repair protein Msh2 (homologous to bacterial MutS) from eukaryotes. Msh2-Msh6 complex recognises base pair mismatches and small insertion/deletions in DNA and initiates repair []. Human Msh2-Msh6 complex has been shown to regulate BLM helicase in response tothe damaged DNA forks during double-stranded break repair []. Mismatch repair (MMR) is one of five major DNA repair pathways. The mismatch repair system recognises and repairs mispaired or unpaired nucleotides that result from errors in DNA replication. The most extensively studied general MMR system is the MutHLS pathway of the bacterium Escherichia coli. In the first step of the MutHLS pathway, the MutS protein (in the form of a dimer) binds to the site of a mismatch in double-stranded DNA. Through a complex interaction between MutS, MutL and MutH, a section of the newly replicated DNA strand (and thus the strand with the replication error) at the location of the mismatch bound by MutS is targeted for removal []. Homologues of MutS have been found in many species including eukaryotes, Archaea and other bacteria, and together these proteins have been grouped into the MutS family.
•
•
•
•
•
Protein Coding Gene
MGI:101816 | Msh2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Gene
644093 | MSH2-OT1
Type: gene
Organism: human
•
•
•
•
•
Protein
G3UXD8
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: true
•
•
•
•
•
Protein
P43247
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
•
•
•
•
•
Publication
12820877 | -
First Author: Antony E
Year: 2003
Journal: Biochemistry
Title: Mismatch recognition-coupled stabilization of Msh2-Msh6 in an ATP-bound state at the initiation of DNA repair.
Volume: 42
Issue: 25
Pages: 7682-93
•
•
•
•
•
Publication
15064730 | -
First Author: Yang Q
Year: 2004
Journal: Oncogene
Title: The mismatch DNA repair heterodimer, hMSH2/6, regulates BLM helicase.
Volume: 23
Issue: 21
Pages: 3749-56
•
•
•
•
•
Publication
7838728 | J:22538
First Author: Varlet I
Year: 1994
Journal: Nucleic Acids Res
Title: Cloning and expression of the Xenopus and mouse Msh2 DNA mismatch repair genes.
Volume: 22
Issue: 25
Pages: 5723-8
•
•
•
•
•
Protein
Q5VIR7
Organism: Mus musculus/domesticus
Length: 275  
Fragment?: true
•
•
•
•
•
Publication
27873144 | J:320945
First Author: Wielders E
Year: 2017
Journal: Fam Cancer
Title: Truncation of the MSH2 C-terminal 60 amino acids disrupts effective DNA mismatch repair and is causative for Lynch syndrome.
Volume: 16
Issue: 2
Pages: 221-229
•
•
•
•
•
Publication
16381012 | J:108203
First Author: Zienolddiny S
Year: 2006
Journal: Int J Cancer
Title: Msh2 deficiency increases susceptibility to benzo[a]pyrene-induced lymphomagenesis.
Volume: 118
Issue: 11
Pages: 2899-902
•
•
•
•
•
Protein
Q3TZI5
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
•
•
•
•
•
Protein
Q80V79
Organism: Mus musculus/domesticus
Length: 935  
Fragment?: false
•
•
•
•
•
Publication
9722651 | -
First Author: Eisen JA
Year: 1998
Journal: Nucleic Acids Res
Title: A phylogenomic study of the MutS family of proteins.
Volume: 26
Issue: 18
Pages: 4291-300
•
•
•
•
•
Publication
7550317 | J:28397
First Author: Reitmair AH
Year: 1995
Journal: Nat Genet
Title: MSH2 deficient mice are viable and susceptible to lymphoid tumours.
Volume: 11
Issue: 1
Pages: 64-70
•
•
•
•
•
Publication
8674041 | J:75393
First Author: Reitmair AH
Year: 1996
Journal: Cancer Res
Title: MSH2 deficiency contributes to accelerated APC-mediated intestinal tumorigenesis.
Volume: 56
Issue: 13
Pages: 2922-6
•
•
•
•
•
Publication
14744764 | J:88092
First Author: Lin DP
Year: 2004
Journal: Cancer Res
Title: An Msh2 point mutation uncouples DNA mismatch repair and apoptosis.
Volume: 64
Issue: 2
Pages: 517-22
•
•
•
•
•
Publication
20923998 | J:166070
First Author: Chalastanis A
Year: 2010
Journal: J Natl Cancer Inst
Title: Azathioprine-induced carcinogenesis in mice according to Msh2 genotype.
Volume: 102
Issue: 22
Pages: 1731-40
•
•
•
•
•
Publication
7713503 | J:47580
First Author: Kolodner RD
Year: 1994
Journal: Genomics
Title: Structure of the human MSH2 locus and analysis of two Muir-Torre kindreds for msh2 mutations.
Volume: 24
Issue: 3
Pages: 516-26
•
•
•
•
•
Publication
24882211 | J:215334
First Author: Zhang M
Year: 2014
Journal: Mol Cell
Title: HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSα.
Volume: 55
Issue: 1
Pages: 31-46
•
•
•
•
•
Publication
19931261 | J:161577
First Author: Kucherlapati MH
Year: 2010
Journal: Gastroenterology
Title: An Msh2 conditional knockout mouse for studying intestinal cancer and testing anticancer agents.
Volume: 138
Issue: 3
Pages: 993-1002.e1
•
•
•
•
•
Publication
18986375 | J:216125
First Author: Martinez P
Year: 2009
Journal: Aging Cell
Title: MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres.
Volume: 8
Issue: 1
Pages: 2-17
•
•
•
•
•
Publication
19436705 | J:149536
First Author: Tomé S
Year: 2009
Journal: PLoS Genet
Title: MSH2 ATPase domain mutation affects CTG*CAG repeat instability in transgenic mice.
Volume: 5
Issue: 5
Pages: e1000482
•
•
•
•
•
Publication
14712231 | J:339372
First Author: Claij N
Year: 2004
Journal: Oncogene
Title: Msh2 deficiency does not contribute to cisplatin resistance in mouse embryonic stem cells.
Volume: 23
Issue: 1
Pages: 260-6
•
•
•
•
•
Publication
17331550 | J:119981
First Author: Burr KL
Year: 2007
Journal: Mutat Res
Title: The effects of MSH2 deficiency on spontaneous and radiation-induced mutation rates in the mouse germline.
Volume: 617
Issue: 1-2
Pages: 147-51
•
•
•
•
•
Publication
20812239 | J:165708
First Author: Leduc C
Year: 2010
Journal: Eur J Immunol
Title: Combined deficiency of MSH2 and Sμ region abolishes class switch recombination.
Volume: 40
Issue: 10
Pages: 2925-31
•
•
•
•
•
Publication
12214270 | J:79081
First Author: Toft NJ
Year: 2002
Journal: Oncogene
Title: Heterozygosity for p53 promotes microsatellite instability and tumorigenesis on a Msh2 deficient background.
Volume: 21
Issue: 41
Pages: 6299-306
•
•
•
•
•
Publication
9288110 | J:42723
First Author: Cranston A
Year: 1997
Journal: Nat Genet
Title: Female embryonic lethality in mice nullizygous for both Msh2 and p53.
Volume: 17
Issue: 1
Pages: 114-8
•
•
•
•
•
Publication
12584170 | J:79407
First Author: Sohn KJ
Year: 2003
Journal: Carcinogenesis
Title: Msh2 deficiency enhances somatic Apc and p53 mutations in Apc+/-Msh2-/- mice.
Volume: 24
Issue: 2
Pages: 217-24
•
•
•
•
•
Publication
27261510 | J:234841
First Author: Eso Y
Year: 2016
Journal: Cancer Res
Title: MSH2 Dysregulation Is Triggered by Proinflammatory Cytokine Stimulation and Is Associated with Liver Cancer Development.
Volume: 76
Issue: 15
Pages: 4383-93
•
•
•
•
•
Publication
12531020 | J:79733
First Author: Meira LB
Year: 2002
Journal: DNA Repair (Amst)
Title: Mice defective in the mismatch repair gene Msh2 show increased predisposition to UVB radiation-induced skin cancer.
Volume: 1
Issue: 11
Pages: 929-34
•
•
•
•
•
Publication
12531021 | J:79734
First Author: Yoshino M
Year: 2002
Journal: DNA Repair (Amst)
Title: Additive roles of XPA and MSH2 genes in UVB-induced skin tumorigenesis in mice.
Volume: 1
Issue: 11
Pages: 935-40
•
•
•
•
•
Publication
16314305 | J:104118
First Author: Larijani M
Year: 2005
Journal: Nucleic Acids Res
Title: Lack of MSH2 involvement differentiates V(D)J recombination from other non-homologous end joining events.
Volume: 33
Issue: 21
Pages: 6733-42
•
•
•
•
•
Publication
22465156 | J:185728
First Author: He D
Year: 2012
Journal: Mutat Res
Title: Role of the Msh2 gene in genome maintenance and development in mouse fetuses.
Volume: 734
Issue: 1-2
Pages: 50-5
•
•
•
•
•
Publication
9244348 | J:41865
First Author: Andrew SE
Year: 1997
Journal: Oncogene
Title: Base transitions dominate the mutational spectrum of a transgenic reporter gene in MSH2 deficient mice.
Volume: 15
Issue: 2
Pages: 123-9
•
•
•
•
•
Publication
11046134 | J:65384
First Author: Jenab-Wolcott J
Year: 2000
Journal: Mol Cell Biol
Title: The absence of Msh2 alters abelson virus pre-B-cell transformation by influencing p53 mutation.
Volume: 20
Issue: 22
Pages: 8373-81
•
•
•
•
•
Publication
7628020 | J:27469
First Author: de Wind N
Year: 1995
Journal: Cell
Title: Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer.
Volume: 82
Issue: 2
Pages: 321-30
•
•
•
•
•
Publication
19435918 | J:148471
First Author: Russo MT
Year: 2009
Journal: Cancer Res
Title: Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis.
Volume: 69
Issue: 10
Pages: 4372-9
•
•
•
•
•
Publication
12554681 | J:81666
First Author: Wheeler VC
Year: 2003
Journal: Hum Mol Genet
Title: Mismatch repair gene Msh2 modifies the timing of early disease in Hdh(Q111) striatum.
Volume: 12
Issue: 3
Pages: 273-81
•
•
•
•
•
Publication
10581038 | J:58797
First Author: Manley K
Year: 1999
Journal: Nat Genet
Title: Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice.
Volume: 23
Issue: 4
Pages: 471-3
•
•
•
•
•
Publication
19596785 | J:152607
First Author: Frieder D
Year: 2009
Journal: Mol Cell Biol
Title: The concerted action of Msh2 and UNG stimulates somatic hypermutation at A . T base pairs.
Volume: 29
Issue: 18
Pages: 5148-57
•
•
•
•
•
Publication
24038355 | J:211221
First Author: Lv L
Year: 2013
Journal: Nucleic Acids Res
Title: Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation.
Volume: 41
Issue: 22
Pages: 10312-22
•
•
•
•
•
Publication
15533840 | J:94447
First Author: van Oosten M
Year: 2005
Journal: DNA Repair (Amst)
Title: Mismatch repair protein Msh2 contributes to UVB-induced cell cycle arrest in epidermal and cultured mouse keratinocytes.
Volume: 4
Issue: 1
Pages: 81-9
•
•
•
•
•
Publication
10097137 | J:54082
First Author: Toft NJ
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Msh2 status modulates both apoptosis and mutation frequency in the murine small intestine.
Volume: 96
Issue: 7
Pages: 3911-5
•
•
•
•
•
Publication
12185594 | J:78943
First Author: Sansom OJ
Year: 2002
Journal: Oncogene
Title: The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient mice.
Volume: 21
Issue: 38
Pages: 5934-9
•
•
•
•
•
Publication
14568978 | J:86278
First Author: Martin A
Year: 2003
Journal: J Exp Med
Title: Msh2 ATPase activity is essential for somatic hypermutation at a-T basepairs and for efficient class switch recombination.
Volume: 198
Issue: 8
Pages: 1171-8
•
•
•
•
•
Publication
10369687 | J:80893
First Author: Ehrenstein MR
Year: 1999
Journal: EMBO J
Title: Deficiency in Msh2 affects the efficiency and local sequence specificity of immunoglobulin class-switch recombination: parallels with somatic hypermutation.
Volume: 18
Issue: 12
Pages: 3484-90
•
•
•
•
•
Publication
11890935 | J:75218
First Author: Zhang S
Year: 2002
Journal: Mutat Res
Title: Thymic lymphomas arising in Msh2 deficient mice display a large increase in mutation frequency and an altered mutational spectrum.
Volume: 500
Issue: 1-2
Pages: 67-74
•
•
•
•
•
Publication
11593414 | J:71905
First Author: Zhang S
Year: 2001
Journal: Oncogene
Title: Msh2 DNA mismatch repair gene deficiency and the food-borne mutagen 2-amino-1-methy1-6-phenolimidazo [4,5-b] pyridine (PhIP) synergistically affect mutagenesis in mouse colon.
Volume: 20
Issue: 42
Pages: 6066-72
•
•
•
•
•
Publication
8252616 | J:22127
First Author: Fishel R
Year: 1993
Journal: Cell
Title: The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.
Volume: 75
Issue: 5
Pages: 1027-38
•
•
•
•
•
Publication
11555625 | J:71822
First Author: Ellison AR
Year: 2001
Journal: Hum Mol Genet
Title: Functional analysis of human MLH1 and MSH2 missense variants and hybrid human-yeast MLH1 proteins in Saccharomyces cerevisiae.
Volume: 10
Issue: 18
Pages: 1889-900
•
•
•
•
•
Publication
9607916 | J:110877
First Author: Phung QH
Year: 1998
Journal: J Exp Med
Title: Increased hypermutation at G and C nucleotides in immunoglobulin variable genes from mice deficient in the MSH2 mismatch repair protein.
Volume: 187
Issue: 11
Pages: 1745-51
•
•
•
•
•
Publication
12531017 | J:79732
First Author: Egashira A
Year: 2002
Journal: DNA Repair (Amst)
Title: Mutational specificity of mice defective in the MTH1 and/or the MSH2 genes.
Volume: 1
Issue: 11
Pages: 881-93
•
•
•
•
•
Publication
9425892 | J:45115
First Author: Toft NJ
Year: 1998
Journal: Nat Genet
Title: No female embryonic lethality in mice nullizygous for Msh2 and p53.
Volume: 18
Issue: 1
Pages: 17
•
•
•
•
•
Publication
26022687 | J:320515
First Author: Winter JM
Year: 2014
Journal: J Nutrigenet Nutrigenomics
Title: Role of Red Meat and Resistant Starch in Promutagenic Adduct Formation, MGMT Repair, Thymic Lymphoma and Intestinal Tumourigenesis in Msh2 -Deficient Mice.
Volume: 7
Issue: 4-6
Pages: 299-313
•
•
•
•
•
Publication
22970194 | J:191886
First Author: Kovalenko M
Year: 2012
Journal: PLoS One
Title: Msh2 acts in medium-spiny striatal neurons as an enhancer of CAG instability and mutant huntingtin phenotypes in Huntington's disease knock-in mice.
Volume: 7
Issue: 9
Pages: e44273
•
•
•
•
•
Publication
12687013 | J:84394
First Author: Franchitto A
Year: 2003
Journal: Oncogene
Title: The mammalian mismatch repair protein MSH2 is required for correct MRE11 and RAD51 relocalization and for efficient cell cycle arrest induced by ionizing radiation in G2 phase.
Volume: 22
Issue: 14
Pages: 2110-20
•
•
•
•
•
Publication
10602475 | J:59017
First Author: Kongkanuntn R
Year: 1999
Journal: Oncogene
Title: Dysregulated expression of beta-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice.
Volume: 18
Issue: 51
Pages: 7219-25
•
•
•
•
•
Publication
9116269 | J:39216
First Author: Lowsky R
Year: 1997
Journal: Blood
Title: Defects of the mismatch repair gene MSH2 are implicated in the development of murine and human lymphoblastic lymphomas and are associated with the aberrant expression of rhombotin-2 (Lmo-2) and Tal-1 (SCL).
Volume: 89
Issue: 7
Pages: 2276-82
•
•
•
•
•
Publication
21804017 | J:179132
First Author: Ranjit S
Year: 2011
Journal: J Immunol
Title: AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].
Volume: 187
Issue: 5
Pages: 2464-75
•
•
•
•
•
Publication
15496421 | J:94584
First Author: Kovtun IV
Year: 2004
Journal: Hum Mol Genet
Title: Somatic deletion events occur during early embryonic development and modify the extent of CAG expansion in subsequent generations.
Volume: 13
Issue: 24
Pages: 3057-68
•
•
•
•
•
Publication
12244177 | J:120202
First Author: Alabyev B
Year: 2002
Journal: J Immunol
Title: Bcl-2 rescues the germinal center response but does not alter the V gene somatic hypermutation spectrum in MSH2-deficient mice.
Volume: 169
Issue: 7
Pages: 3819-24
•
•
•
•
•
Publication
15955838 | J:99207
First Author: Min IM
Year: 2005
Journal: J Exp Med
Title: Shifts in targeting of class switch recombination sites in mice that lack mu switch region tandem repeats or Msh2.
Volume: 201
Issue: 12
Pages: 1885-90
•
•
•
•
•
Publication
9697843 | J:48834
First Author: Rada C
Year: 1998
Journal: Immunity
Title: Hot spot focusing of somatic hypermutation in MSH2-deficient mice suggests two stages of mutational targeting.
Volume: 9
Issue: 1
Pages: 135-41
•
•
•
•
•
Publication
14563316 | J:99462
First Author: Min IM
Year: 2003
Journal: Immunity
Title: The Smu tandem repeat region is critical for Ig isotype switching in the absence of Msh2.
Volume: 19
Issue: 4
Pages: 515-24
•
•
•
•
•
Publication
12606123 | J:82381
First Author: Peters AC
Year: 2003
Journal: DNA Repair (Amst)
Title: Mammalian DNA mismatch repair protects cells from UVB-induced DNA damage by facilitating apoptosis and p53 activation.
Volume: 2
Issue: 4
Pages: 427-35
•
•
•
•
•
Publication
9927509 | J:52568
First Author: Vora KA
Year: 1999
Journal: J Exp Med
Title: Severe attenuation of the B cell immune response in Msh2-deficient mice.
Volume: 189
Issue: 3
Pages: 471-82
•
•
•
•
•
Publication
36715327 | J:333478
First Author: Bruekner SR
Year: 2023
Journal: Nucleic Acids Res
Title: Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.
Volume: 51
Issue: 3
Pages: 1173-1188
•
•
•
•
•
Publication
10747038 | J:61445
First Author: Oda S
Year: 2000
Journal: EMBO J
Title: Efficient repair of A/C mismatches in mouse cells deficient in long-patch mismatch repair.
Volume: 19
Issue: 7
Pages: 1711-8
•
•
•
•
•
Publication
15700306 | J:98929
First Author: Kabbarah O
Year: 2005
Journal: Int J Cancer
Title: Diethylstilbestrol effects and lymphomagenesis in Mlh1-deficient mice.
Volume: 115
Issue: 4
Pages: 666-9
•
•
•
•
•
Publication
10662804 | J:60285
First Author: Wiesendanger M
Year: 2000
Journal: J Exp Med
Title: Somatic hypermutation in MutS homologue (MSH)3-, MSH6-, and MSH3/MSH6-deficient mice reveals a role for the MSH2-MSH6 heterodimer in modulating the base substitution pattern.
Volume: 191
Issue: 3
Pages: 579-84
•
•
•
•
•
Publication
10837019 | J:62878
First Author: Baross-Francis A
Year: 2000
Journal: Carcinogenesis
Title: Tumors arising in DNA mismatch repair-deficient mice show a wide variation in mutation frequency as assessed by a transgenic reporter gene.
Volume: 21
Issue: 6
Pages: 1259-62
•
•
•
•
•
Publication
12195036 | J:102776
First Author: Qin J
Year: 2002
Journal: J Hered
Title: Evidence for the lack of mismatch-repair directed antirecombination during mouse meiosis.
Volume: 93
Issue: 3
Pages: 201-5
•
•
•
•
•
Publication
11429706 | J:70198
First Author: Sansom OJ
Year: 2001
Journal: Oncogene
Title: Msh-2 suppresses in vivo mutation in a gene dose and lesion dependent manner.
Volume: 20
Issue: 27
Pages: 3580-4
•
•
•
•
•
Publication
12727820 | J:83054
First Author: Claij N
Year: 2003
Journal: Cancer Res
Title: DNA mismatch repair deficiency stimulates N-ethyl-N-nitrosourea-induced mutagenesis and lymphomagenesis.
Volume: 63
Issue: 9
Pages: 2062-6
•
•
•
•
•
Publication
11133819 | J:66877
First Author: Campbell MR
Year: 2000
Journal: Carcinogenesis
Title: Candidate mutator genes in mismatch repair-deficient thymic lymphomas: no evidence of mutations in the DNA polymerase delta gene.
Volume: 21
Issue: 12
Pages: 2281-5
•
•
•
•
•
Publication
11283247 | J:68371
First Author: Elliott B
Year: 2001
Journal: Mol Cell Biol
Title: Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells.
Volume: 21
Issue: 8
Pages: 2671-82
•
•
•
•
•
Publication
21865299 | J:176887
First Author: Williams SA
Year: 2011
Journal: Hum Mol Genet
Title: Functional and physical interaction between the mismatch repair and FA-BRCA pathways.
Volume: 20
Issue: 22
Pages: 4395-410
•
•
•
•
•
Publication
17142234 | J:118264
First Author: Aarts M
Year: 2006
Journal: Nucleic Acids Res
Title: Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells.
Volume: 34
Issue: 21
Pages: e147
•
•
•
•
•
Publication
19901081 | J:155454
First Author: Krijger PH
Year: 2009
Journal: J Exp Med
Title: Dependence of nucleotide substitutions on Ung2, Msh2, and PCNA-Ub during somatic hypermutation.
Volume: 206
Issue: 12
Pages: 2603-11
•
•
•
•
•
Publication
26385350 | J:231111
First Author: Gu X
Year: 2016
Journal: Blood
Title: AID-associated DNA repair pathways regulate malignant transformation in a murine model of BCL6-driven diffuse large B-cell lymphoma.
Volume: 127
Issue: 1
Pages: 102-12
•
•
•
•
•
Publication
25773971 | J:317233
First Author: Downey CM
Year: 2015
Journal: Cancer Med
Title: DNA mismatch repair deficiency accelerates lung neoplasm development in K-ras(LA1/+) mice: a brief report.
Volume: 4
Issue: 6
Pages: 897-902
•
•
•
•
•
Publication
21788338 | J:177080
First Author: Green B
Year: 2011
Journal: Blood
Title: The mismatch repair pathway functions normally at a non-AID target in germinal center B cells.
Volume: 118
Issue: 11
Pages: 3013-8
•
•
•
•
•
Publication
15135636 | J:90162
First Author: Hooker AM
Year: 2004
Journal: Mutat Res
Title: Cancer-associated genes can affect somatic intrachromosomal recombination early in carcinogenesis.
Volume: 550
Issue: 1-2
Pages: 1-10
•
•
•
•
•
Publication
34224739 | J:311102
First Author: Gebert J
Year: 2021
Journal: Gastroenterology
Title: Recurrent Frameshift Neoantigen Vaccine Elicits Protective Immunity With Reduced Tumor Burden and Improved Overall Survival in a Lynch Syndrome Mouse Model.
Volume: 161
Issue: 4
Pages: 1288-1302.e13
•
•
•
•
•
Publication
11929830 | J:75751
First Author: Kohonen-Corish MR
Year: 2002
Journal: Cancer Res
Title: Susceptibility of Msh2-deficient mice to inflammation-associated colorectal tumors.
Volume: 62
Issue: 7
Pages: 2092-7
•
•
•
•
•
Publication
11604476 | J:72174
First Author: Colussi C
Year: 2001
Journal: J Natl Cancer Inst
Title: 1,2-Dimethylhydrazine-induced colon carcinoma and lymphoma in msh2(-/-) mice.
Volume: 93
Issue: 20
Pages: 1534-40
•
•
•
•
•
Publication
19553545 | J:151397
First Author: Eccleston J
Year: 2009
Journal: J Immunol
Title: Class switch recombination efficiency and junction microhomology patterns in Msh2-, Mlh1-, and Exo1-deficient mice depend on the presence of mu switch region tandem repeats.
Volume: 183
Issue: 2
Pages: 1222-8
•
•
•
•
•
Publication
12743174 | J:83489
First Author: Schrader CE
Year: 2003
Journal: J Exp Med
Title: Mlh1 can function in antibody class switch recombination independently of Msh2.
Volume: 197
Issue: 10
Pages: 1377-83
•
•
•
•
•
Publication
23935891 | J:204691
First Author: Kucherlapati MH
Year: 2013
Journal: PLoS One
Title: Genotype directed therapy in murine mismatch repair deficient tumors.
Volume: 8
Issue: 7
Pages: e68817
•
•
•
•
•
Publication
31757865 | J:293653
First Author: Choi JE
Year: 2020
Journal: J Immunol
Title: AID Phosphorylation Regulates Mismatch Repair-Dependent Class Switch Recombination and Affinity Maturation.
Volume: 204
Issue: 1
Pages: 13-22
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom