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Search results 1 to 93 out of 93 for Msl2

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
55167 | MSL2
Type: gene
Organism: human
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Gene
470933 | MSL2
Type: gene
Organism: chimpanzee
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Gene
525740 | MSL2
Type: gene
Organism: cattle
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Gene
429119 | MSL2
Type: gene
Organism: chicken
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Gene
717049 | MSL2
Type: gene
Organism: macaque, rhesus
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Gene
100125142 | msl2
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR037922 | MSL2
Type: Family
Description: E3 ubiquitin-protein ligase MSL2 (MSL2; [intenz:6.3.2.-]) is an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. It is a component of MSL complex [].The male-specific lethal (MSL) complex is a histone acetyltransferase with specificity for histone H4 'lysine-16' in chromatin. The complex consists of MOF, MSL1, MSL2, and MSL3 []. The complex was first identified in Drosophila.
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Gene
315959 | Msl2
Type: gene
Organism: rat
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Gene
485673 | MSL2
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1925103 | Msl2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q69ZF8
Organism: Mus musculus/domesticus
Length: 577  
Fragment?: false
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Protein
A0A087WNL5
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: false
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Publication
38030723 | J:344688
First Author: Sun Y
Year: 2023
Journal: Nature
Title: MSL2 ensures biallelic gene expression in mammals.
Volume: 624
Issue: 7990
Pages: 173-181
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Publication
23084835 | -
First Author: Hallacli E
Year: 2012
Journal: Mol Cell
Title: Msl1-mediated dimerization of the dosage compensation complex is essential for male X-chromosome regulation in Drosophila.
Volume: 48
Issue: 4
Pages: 587-600
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Publication
23874665 | J:225193
First Author: Lai Z
Year: 2013
Journal: PLoS One
Title: Msl2 is a novel component of the vertebrate DNA damage response.
Volume: 8
Issue: 7
Pages: e68549
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Publication
16227571 | -
First Author: Smith ER
Year: 2005
Journal: Mol Cell Biol
Title: A human protein complex homologous to the Drosophila MSL complex is responsible for the majority of histone H4 acetylation at lysine 16.
Volume: 25
Issue: 21
Pages: 9175-88
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Protein Coding Gene
MGP_CAROLIEiJ_G0032574 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035162 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1925103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035675 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034982 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033883 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015443 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033719 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115827
Age: embryonic day 14.5
Image: 2
Specimen Label: WT-M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115827
Age: embryonic day 14.5
Image: 2
Specimen Label: KO-M
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115834
Age: embryonic day 10.5
Image: S1
Specimen Label: WT-M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115834
Age: embryonic day 10.5
Image: S1
Specimen Label: KO-M
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115847
Age: embryonic day 18.5
Image: S1
Specimen Label: WT-M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Male
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115847
Age: embryonic day 18.5
Image: S1
Specimen Label: KO-M
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115822
Age: embryonic day 14.5
Image: 2
Specimen Label: WT-F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:6115822
Age: embryonic day 14.5
Image: 2
Specimen Label: KO-F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115839
Age: embryonic day 10.5
Image: S1
Specimen Label: WT-F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:6115839
Age: embryonic day 10.5
Image: S1
Specimen Label: KO-F
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115846
Age: embryonic day 18.5
Image: S1
Specimen Label: WT-F
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6115783
Assay Type: RT-PCR
Annotation Date: 2018-02-13
Strength: Present
Sex: Female
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6115846
Age: embryonic day 18.5
Image: S1
Specimen Label: KO-F
Detected: true
Specimen Num: 2
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Publication
12698291 | J:82856
First Author: Marín I
Year: 2003
Journal: J Mol Evol
Title: Evolution of chromatin-remodeling complexes: comparative genomics reveals the ancient origin of "novel" compensasome genes.
Volume: 56
Issue: 5
Pages: 527-39
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Publication
23210685 | J:206774
First Author: Wolstenholme JT
Year: 2013
Journal: Genes Brain Behav
Title: Sexual differentiation in the developing mouse brain: contributions of sex chromosome genes.
Volume: 12
Issue: 2
Pages: 166-80
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Publication
24842875 | J:313850
 
First Author: Chelmicki T
Year: 2014
Journal: Elife
Title: MOF-associated complexes ensure stem cell identity and Xist repression.
Volume: 3
Pages: e02024
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Publication
28609438 | J:246912
First Author: Ye A
Year: 2017
Journal: PLoS One
Title: PEG3 control on the mammalian MSL complex.
Volume: 12
Issue: 6
Pages: e0178363
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: E3 ubiquitin-protein ligase MSL2
Type: chain
End: 577
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Publication
23029009 | -
First Author: Zheng S
Year: 2012
Journal: PLoS One
Title: Solution structure of MSL2 CXC domain reveals an unusual Zn3Cys9 cluster and similarity to pre-SET domains of histone lysine methyltransferases.
Volume: 7
Issue: 9
Pages: e45437
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Protein Domain
IPR032049 | Msl2-CXC
Type: Domain
Description: This entry represents an autonomously folded domain that binds three zinc ions. This domain can be found in E3 ubiquitin-protein ligase Msl2 from eukaryotes. The CXC domain critically contributes to the DNA-binding activity of Msl2 []. It carries 9 invariant cysteines within about a 50 residue region.
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GO Term
GO:0072487 | MSL complex
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Protein Domain
IPR031840 | MSL1_dimer
Type: Domain
Description: This entry represents the short coiled dimerisation domain of higher eukaryotic MSL1, part of the MSL or Male-Specific Lethal complex. This complex regulates the dosage compensation of the male X chromosome in Drosophila and other eukaryotes. The structure of the MSL1/MSL2 core shows that two MSL2 subunits bind to a dimer formed by two molecules of MSL1. MSL1 is a substrate for MSL2 E3 ubiquitin ligase activity [].
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Protein Coding Gene
MGI:1920640 | Msl3l2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q6PDM1
Organism: Mus musculus/domesticus
Length: 616  
Fragment?: false
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Protein Coding Gene
MGI:1921276 | Msl1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1341851 | Msl3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1915023 | Kat8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1932051 | Kat5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15368895 | J:92575
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
19468303 | -
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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