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Search results 1 to 100 out of 5081 for Mtor

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
100491970 | mtor
Type: gene
Organism: frog, western clawed
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Gene
106992736 | MTOR
Type: gene
Organism: macaque, rhesus
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Gene
2475 | MTOR
Type: gene
Organism: human
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Gene
56718 | Mtor
Type: gene
Organism: rat
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Gene
457945 | MTOR
Type: gene
Organism: chimpanzee
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Gene
478232 | MTOR
Type: gene
Organism: dog, domestic
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Gene
100139219 | MTOR
Type: gene
Organism: cattle
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Gene
419455 | MTOR
Type: gene
Organism: chicken
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Gene
324254 | mtor
Type: gene
Organism: zebrafish
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Protein Coding Gene
MGI:1928394 | Mtor
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Widespread
Stage: TS02
Assay Id: MGI:6755548
Age: embryonic day 1.0
Image: 7B mTOR
Note: Expression throughout embryo.
Specimen Label: 7B mTOR
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5796583
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384546
Age: embryonic day 15.5
Image: 5a mTOR WT
Note: Widely expressed throughout cortical primordium
Specimen Label: 5a mTOR WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:5796583
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384546
Age: embryonic day 15.5
Image: 5a mTOR Fmr1 KO
Note: No difference compared with wild type.
Specimen Label: 5a mTOR Fmr1 KO
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Widespread
Stage: TS03
Assay Id: MGI:6755548
Age: embryonic day 2.0
Image: 7C mTOR 4-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 4-c
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Widespread
Stage: TS01
Assay Id: MGI:6755548
Age: embryonic day 0.5
Image: 7C mTOR 1-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 1-c
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Widespread
Stage: TS03
Assay Id: MGI:6755548
Age: embryonic day 2.5
Image: 7C mTOR 8-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 8-c
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Widespread
Stage: TS04
Assay Id: MGI:6755548
Age: embryonic day 3.5
Image: 7C mTOR Blastocyst
Note: Expression throughout embryo.
Specimen Label: 7C mTOR Blastocyst
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:6755548
Age: postnatal adult
Image: 7C mTOR Ooc
Specimen Label: 7C mTOR Ooc
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Widespread
Stage: TS02
Assay Id: MGI:6755548
Age: embryonic day 1.0
Image: 7C mTOR 2-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 2-c
Detected: true
Specimen Num: 4
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Publication
15485918 | J:94133
First Author: Gangloff YG
Year: 2004
Journal: Mol Cell Biol
Title: Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.
Volume: 24
Issue: 21
Pages: 9508-16
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Publication
19487463 | J:151331
First Author: Acosta-Jaquez HA
Year: 2009
Journal: Mol Cell Biol
Title: Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
Volume: 29
Issue: 15
Pages: 4308-24
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Publication
18046414 | J:128527
First Author: Cunningham JT
Year: 2007
Journal: Nature
Title: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Volume: 450
Issue: 7170
Pages: 736-40
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Publication
29750810 | J:263234
First Author: Ramanathan C
Year: 2018
Journal: PLoS Genet
Title: mTOR signaling regulates central and peripheral circadian clock function.
Volume: 14
Issue: 5
Pages: e1007369
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Publication
21258367 | J:175316
First Author: Kim J
Year: 2011
Journal: Nat Cell Biol
Title: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Volume: 13
Issue: 2
Pages: 132-41
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Publication
23027611 | J:215861
First Author: Meffre J
Year: 2012
Journal: EMBO Mol Med
Title: 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
Volume: 4
Issue: 10
Pages: 1043-56
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Publication
16962829 | J:119564
First Author: Shiota C
Year: 2006
Journal: Dev Cell
Title: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.
Volume: 11
Issue: 4
Pages: 583-9
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Publication
21321111 | J:355659
First Author: Wu YT
Year: 2011
Journal: J Biol Chem
Title: mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif.
Volume: 286
Issue: 16
Pages: 14190-8
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Gene
64223 | MLST8
Type: gene
Organism: human
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Gene
57707 | MEAK7
Type: gene
Organism: human
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Gene
100873935 | MTOR-AS1
Type: gene
Organism: human
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Publication
25336251 | J:225705
 
First Author: Scheffler JM
Year: 2014
Journal: Nat Commun
Title: LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.
Volume: 5
Pages: 5138
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Publication
28283069 | J:320286
First Author: Saxton RA
Year: 2017
Journal: Cell
Title: mTOR Signaling in Growth, Metabolism, and Disease.
Volume: 168
Issue: 6
Pages: 960-976
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Publication
20801936 | J:164024
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
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Publication
18566587 | J:137601
First Author: Ikenoue T
Year: 2008
Journal: EMBO J
Title: Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling.
Volume: 27
Issue: 14
Pages: 1919-31
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Publication
22500797 | J:319697
First Author: Laplante M
Year: 2012
Journal: Cell
Title: mTOR signaling in growth control and disease.
Volume: 149
Issue: 2
Pages: 274-93
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Publication
27913603 | J:285017
First Author: Wada S
Year: 2016
Journal: Genes Dev
Title: The tumor suppressor FLCN mediates an alternate mTOR pathway to regulate browning of adipose tissue.
Volume: 30
Issue: 22
Pages: 2551-2564
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Publication
19704009 | J:153992
First Author: Liu GH
Year: 2009
Journal: Mol Cell Biol
Title: Regulation of myoblast differentiation by the nuclear envelope protein NET39.
Volume: 29
Issue: 21
Pages: 5800-12
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Publication
11930000 | J:384328
First Author: Desai BN
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: FKBP12-rapamycin-associated protein associates with mitochondria and senses osmotic stress via mitochondrial dysfunction.
Volume: 99
Issue: 7
Pages: 4319-24
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Publication
21045808 | J:167176
First Author: Oh WJ
Year: 2010
Journal: EMBO J
Title: mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide.
Volume: 29
Issue: 23
Pages: 3939-51
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Publication
25418727 | J:338236
First Author: Lee D
Year: 2014
Journal: Stem Cell Reports
Title: Transmembrane Inhibitor of RICTOR/mTORC2 in Hematopoietic Progenitors.
Volume: 3
Issue: 5
Pages: 832-40
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Publication
37532788 | J:341188
First Author: Fan C
Year: 2023
Journal: Leukemia
Title: Kinase-independent role of mTOR and on-/off-target effects of an mTOR kinase inhibitor.
Volume: 37
Issue: 10
Pages: 2073-2081
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Publication
29150432 | J:257513
First Author: Bodur C
Year: 2018
Journal: EMBO J
Title: The IKK-related kinase TBK1 activates mTORC1 directly in response to growth factors and innate immune agonists.
Volume: 37
Issue: 1
Pages: 19-38
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Publication
34245780 | J:328512
First Author: Tooley AS
Year: 2021
Journal: J Biol Chem
Title: The innate immune kinase TBK1 directly increases mTORC2 activity and downstream signaling to Akt.
Volume: 297
Issue: 2
Pages: 100942
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Publication
33971888 | J:370073
First Author: Wang L
Year: 2021
Journal: J Transl Med
Title: mTOR regulates GPVI-mediated platelet activation.
Volume: 19
Issue: 1
Pages: 201
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Publication
19185849 | J:144810
First Author: Guertin DA
Year: 2009
Journal: Cancer Cell
Title: mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Volume: 15
Issue: 2
Pages: 148-59
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Publication
23388827 | J:193606
First Author: Dai N
Year: 2013
Journal: Genes Dev
Title: mTOR complex 2 phosphorylates IMP1 cotranslationally to promote IGF2 production and the proliferation of mouse embryonic fibroblasts.
Volume: 27
Issue: 3
Pages: 301-12
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Publication
39957408 | J:373724
First Author: Chowdhury O
Year: 2025
Journal: Aging Cell
Title: Activated mTOR Signaling in the RPE Drives EMT, Autophagy, and Metabolic Disruption, Resulting in AMD-Like Pathology in Mice.
Volume: 24
Issue: 6
Pages: e70018
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Publication
18566586 | J:137614
First Author: Facchinetti V
Year: 2008
Journal: EMBO J
Title: The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C.
Volume: 27
Issue: 14
Pages: 1932-43
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Publication
31548312 | J:282915
First Author: Kearney AL
Year: 2019
Journal: J Biol Chem
Title: Serine 474 phosphorylation is essential for maximal Akt2 kinase activity in adipocytes.
Volume: 294
Issue: 45
Pages: 16729-16739
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Publication
32289154 | J:288637
 
First Author: Ramalingam P
Year: 2020
Journal: J Exp Med
Title: Endothelial mTOR maintains hematopoiesis during aging.
Volume: 217
Issue: 6
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Publication
23142081 | J:193983
First Author: Kim SJ
Year: 2012
Journal: Mol Cell
Title: mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.
Volume: 48
Issue: 6
Pages: 875-87
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Publication
19176516 | J:261276
First Author: Nardella C
Year: 2009
Journal: Sci Signal
Title: Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Volume: 2
Issue: 55
Pages: ra2
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Publication
23716557 | J:205539
First Author: Guo F
Year: 2013
Journal: Haematologica
Title: Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis.
Volume: 98
Issue: 9
Pages: 1353-8
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Publication
23102618 | J:190892
First Author: Bayeva M
Year: 2012
Journal: Cell Metab
Title: mTOR regulates cellular iron homeostasis through tristetraprolin.
Volume: 16
Issue: 5
Pages: 645-57
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Publication
33443202 | J:300033
 
First Author: Fan C
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.
Volume: 118
Issue: 1
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Publication
29384525 | J:267927
First Author: Hassan Z
Year: 2018
Journal: Br J Cancer
Title: MTOR inhibitor-based combination therapies for pancreatic cancer.
Volume: 118
Issue: 3
Pages: 366-377
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Publication
16915281 | J:111744
First Author: Bernardi R
Year: 2006
Journal: Nature
Title: PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR.
Volume: 442
Issue: 7104
Pages: 779-85
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Publication
15467718 | J:93907
First Author: Jacinto E
Year: 2004
Journal: Nat Cell Biol
Title: Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive.
Volume: 6
Issue: 11
Pages: 1122-8
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Publication
24717934 | J:310016
First Author: Morran DC
Year: 2014
Journal: Gut
Title: Targeting mTOR dependency in pancreatic cancer.
Volume: 63
Issue: 9
Pages: 1481-9
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Publication
37979583 | J:343575
First Author: Ge MK
Year: 2023
Journal: Cell Metab
Title: The tRNA-GCN2-FBXO22-axis-mediated mTOR ubiquitination senses amino acid insufficiency.
Volume: 35
Issue: 12
Pages: 2216-2230.e8
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Publication
21512002 | J:172208
First Author: Narita M
Year: 2011
Journal: Science
Title: Spatial coupling of mTOR and autophagy augments secretory phenotypes.
Volume: 332
Issue: 6032
Pages: 966-70
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Publication
34309874 | J:317932
First Author: Jiao L
Year: 2021
Journal: J Pathol
Title: Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer.
Volume: 255
Issue: 3
Pages: 270-284
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Publication
17141160 | J:137592
First Author: Guertin DA
Year: 2006
Journal: Dev Cell
Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Volume: 11
Issue: 6
Pages: 859-71
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Publication
27340174 | J:233300
First Author: Smithson LJ
Year: 2016
Journal: Genes Dev
Title: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Volume: 30
Issue: 12
Pages: 1383-8
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Publication
29625033 | J:262039
First Author: Jia J
Year: 2018
Journal: Mol Cell
Title: Galectins Control mTOR in Response to Endomembrane Damage.
Volume: 70
Issue: 1
Pages: 120-135.e8
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Publication
27880763 | J:242988
First Author: Bulut-Karslioglu A
Year: 2016
Journal: Nature
Title: Inhibition of mTOR induces a paused pluripotent state.
Volume: 540
Issue: 7631
Pages: 119-123
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Publication
20670887 | J:163259
First Author: D?vel K
Year: 2010
Journal: Mol Cell
Title: Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Volume: 39
Issue: 2
Pages: 171-83
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Publication
29143288 | J:367331
First Author: Urbanska M
Year: 2018
Journal: Mol Neurobiol
Title: GSK3? Controls mTOR and Prosurvival Signaling in Neurons.
Volume: 55
Issue: 7
Pages: 6050-6062
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Publication
23538752 | J:201860
First Author: Guo F
Year: 2013
Journal: Leukemia
Title: mTOR regulates DNA damage response through NF-?B-mediated FANCD2 pathway in hematopoietic cells.
Volume: 27
Issue: 10
Pages: 2040-2046
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Publication
27524416 | J:305118
First Author: Chen R
Year: 2017
Journal: Oncogene
Title: mTOR promotes pituitary tumor development through activation of PTTG1.
Volume: 36
Issue: 7
Pages: 979-988
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Publication
29567716 | J:261780
First Author: Terenzio M
Year: 2018
Journal: Science
Title: Locally translated mTOR controls axonal local translation in nerve injury.
Volume: 359
Issue: 6382
Pages: 1416-1421
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Publication
29720621 | J:263661
First Author: Zhu C
Year: 2018
Journal: Sci Rep
Title: mTOR complexes differentially orchestrates eosinophil development in allergy.
Volume: 8
Issue: 1
Pages: 6883
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Gene
253260 | RICTOR
Type: gene
Organism: human
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Gene
57521 | RPTOR
Type: gene
Organism: human
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Gene
8649 | LAMTOR3
Type: gene
Organism: human
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Gene
28956 | LAMTOR2
Type: gene
Organism: human
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Gene
64798 | DEPTOR
Type: gene
Organism: human
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Gene
55004 | LAMTOR1
Type: gene
Organism: human
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Gene
10542 | LAMTOR5
Type: gene
Organism: human
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Gene
389541 | LAMTOR4
Type: gene
Organism: human
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Publication
28381544 | J:242296
First Author: Li R
Year: 2017
Journal: Cancer Res
Title: Modulation of Bax and mTOR for Cancer Therapeutics.
Volume: 77
Issue: 11
Pages: 3001-3012
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Publication
23129577 | J:316435
First Author: Carr TD
Year: 2012
Journal: Cancer Prev Res (Phila)
Title: Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.
Volume: 5
Issue: 12
Pages: 1394-404
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Publication
22561297 | J:189057
First Author: Aoyagi T
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac mTOR protects the heart against ischemia-reperfusion injury.
Volume: 303
Issue: 1
Pages: H75-85
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Publication
32917361 | J:304752
First Author: Tokumura K
Year: 2020
Journal: Biochem Biophys Res Commun
Title: mTOR regulates skeletogenesis through canonical and noncanonical pathways.
Volume: 533
Issue: 1
Pages: 30-35
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Publication
32282093 | J:301777
First Author: Pan X
Year: 2020
Journal: FASEB J
Title: Accumulation of prelamin A induces premature aging through mTOR overactivation.
Volume: 34
Issue: 6
Pages: 7905-7914
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Publication
16221682 | J:104099
First Author: Hresko RC
Year: 2005
Journal: J Biol Chem
Title: mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes.
Volume: 280
Issue: 49
Pages: 40406-16
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Publication
21310925 | J:172837
First Author: Gorentla BK
Year: 2011
Journal: Blood
Title: Negative regulation of mTOR activation by diacylglycerol kinases.
Volume: 117
Issue: 15
Pages: 4022-31
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Publication
24481314 | J:206952
First Author: Khapre RV
Year: 2014
Journal: Aging (Albany NY)
Title: BMAL1-dependent regulation of the mTOR signaling pathway delays aging.
Volume: 6
Issue: 1
Pages: 48-57
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Publication
22193387 | J:184667
First Author: Cin? DP
Year: 2012
Journal: J Am Soc Nephrol
Title: Inhibition of MTOR disrupts autophagic flux in podocytes.
Volume: 23
Issue: 3
Pages: 412-20
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Publication
23454868 | J:267894
First Author: Liu Y
Year: 2013
Journal: Aging (Albany NY)
Title: Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development.
Volume: 5
Issue: 2
Pages: 111-9
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Publication
26279396 | J:229176
 
First Author: Xu G
Year: 2015
Journal: Mol Cell Endocrinol
Title: Ghrelin regulates GLP-1 production through mTOR signaling in L cells.
Volume: 416
Pages: 9-18
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Publication
30318987 | J:295690
First Author: Xu Z
Year: 2019
Journal: Adipocyte
Title: Elucidating the role of Lkb1 and mTOR in adipose tissue.
Volume: 8
Issue: 1
Pages: 26-30
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Publication
21284988 | J:169560
First Author: Kim S
Year: 2011
Journal: Cell Metab
Title: Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase.
Volume: 13
Issue: 2
Pages: 215-21
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Publication
19733540 | J:154125
First Author: Castilho RM
Year: 2009
Journal: Cell Stem Cell
Title: mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Volume: 5
Issue: 3
Pages: 279-89
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Publication
29555746 | J:261082
First Author: Liu D
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.
Volume: 115
Issue: 14
Pages: E3296-E3304
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Publication
26631481 | J:230899
First Author: Sampson LL
Year: 2016
Journal: FASEB J
Title: mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice.
Volume: 30
Issue: 3
Pages: 1263-75
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Publication
21750711 | J:176072
First Author: Yu J
Year: 2011
Journal: PLoS One
Title: mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
Volume: 6
Issue: 7
Pages: e21415
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Publication
41223856 | J:386569
First Author: Li Y
Year: 2025
Journal: Cell Chem Biol
Title: Lactylation of mTOR enhances autophagy in skeletal muscle during exercise.
Volume: 32
Issue: 11
Pages: 1367-1380.e5
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Publication
26418749 | J:309334
First Author: Wu M
Year: 2015
Journal: Oncotarget
Title: Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
Volume: 6
Issue: 32
Pages: 32761-73
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Publication
26416965 | J:227652
First Author: Bao Y
Year: 2015
Journal: J Cell Biol
Title: mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.
Volume: 210
Issue: 7
Pages: 1153-64
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