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Search results 1 to 100 out of 3909 for Mtor

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Type Details Score
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Widespread
Stage: TS02
Assay Id: MGI:6755548
Age: embryonic day 1.0
Image: 7B mTOR
Note: Expression throughout embryo.
Specimen Label: 7B mTOR
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160331
Pattern: Widespread
Stage: TS01
Assay Id: MGI:6755548
Age: embryonic day 0.5
Image: 7C mTOR 1-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 1-c
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Pattern: Widespread
Stage: TS02
Assay Id: MGI:6755548
Age: embryonic day 1.0
Image: 7C mTOR 2-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 2-c
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Pattern: Widespread
Stage: TS03
Assay Id: MGI:6755548
Age: embryonic day 2.0
Image: 7C mTOR 4-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 4-c
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318653
Pattern: Widespread
Stage: TS03
Assay Id: MGI:6755548
Age: embryonic day 2.5
Image: 7C mTOR 8-c
Note: Expression throughout embryo.
Specimen Label: 7C mTOR 8-c
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360354
Pattern: Widespread
Stage: TS04
Assay Id: MGI:6755548
Age: embryonic day 3.5
Image: 7C mTOR Blastocyst
Note: Expression throughout embryo.
Specimen Label: 7C mTOR Blastocyst
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6755523
Assay Type: Immunohistochemistry
Annotation Date: 2021-09-01
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Pattern: Widespread
Stage: TS28
Assay Id: MGI:6755548
Age: postnatal adult
Image: 7C mTOR Ooc
Specimen Label: 7C mTOR Ooc
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5796583
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384546
Age: embryonic day 15.5
Image: 5a mTOR WT
Note: Widely expressed throughout cortical primordium
Specimen Label: 5a mTOR WT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5796583
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384546
Age: embryonic day 15.5
Image: 5a mTOR Fmr1 KO
Note: No difference compared with wild type.
Specimen Label: 5a mTOR Fmr1 KO
Detected: true
Specimen Num: 2
Publication
First Author: Acosta-Jaquez HA
Year: 2009
Journal: Mol Cell Biol
Title: Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
Volume: 29
Issue: 15
Pages: 4308-24
Publication
First Author: Ramanathan C
Year: 2018
Journal: PLoS Genet
Title: mTOR signaling regulates central and peripheral circadian clock function.
Volume: 14
Issue: 5
Pages: e1007369
Publication
First Author: Cunningham JT
Year: 2007
Journal: Nature
Title: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Volume: 450
Issue: 7170
Pages: 736-40
Publication  
First Author: Scheffler JM
Year: 2014
Journal: Nat Commun
Title: LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.
Volume: 5
Pages: 5138
Gene
Type: gene
Organism: human
Publication
First Author: Meffre J
Year: 2012
Journal: EMBO Mol Med
Title: 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
Volume: 4
Issue: 10
Pages: 1043-56
Publication
First Author: Saxton RA
Year: 2017
Journal: Cell
Title: mTOR Signaling in Growth, Metabolism, and Disease.
Volume: 168
Issue: 6
Pages: 960-976
Publication
First Author: Shiota C
Year: 2006
Journal: Dev Cell
Title: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.
Volume: 11
Issue: 4
Pages: 583-9
Publication
First Author: Laplante M
Year: 2012
Journal: Cell
Title: mTOR signaling in growth control and disease.
Volume: 149
Issue: 2
Pages: 274-93
Publication
First Author: Kim J
Year: 2011
Journal: Nat Cell Biol
Title: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Volume: 13
Issue: 2
Pages: 132-41
Publication
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
Publication
First Author: Fan C
Year: 2023
Journal: Leukemia
Title: Kinase-independent role of mTOR and on-/off-target effects of an mTOR kinase inhibitor.
Volume: 37
Issue: 10
Pages: 2073-2081
Publication
First Author: Guertin DA
Year: 2009
Journal: Cancer Cell
Title: mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Volume: 15
Issue: 2
Pages: 148-59
Publication  
First Author: Ramalingam P
Year: 2020
Journal: J Exp Med
Title: Endothelial mTOR maintains hematopoiesis during aging.
Volume: 217
Issue: 6
Publication
First Author: Nardella C
Year: 2009
Journal: Sci Signal
Title: Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Volume: 2
Issue: 55
Pages: ra2
Publication
First Author: Guertin DA
Year: 2006
Journal: Dev Cell
Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Volume: 11
Issue: 6
Pages: 859-71
Publication
First Author: Guo F
Year: 2013
Journal: Haematologica
Title: Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis.
Volume: 98
Issue: 9
Pages: 1353-8
Publication
First Author: Bayeva M
Year: 2012
Journal: Cell Metab
Title: mTOR regulates cellular iron homeostasis through tristetraprolin.
Volume: 16
Issue: 5
Pages: 645-57
Publication  
First Author: Fan C
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.
Volume: 118
Issue: 1
Publication
First Author: Hassan Z
Year: 2018
Journal: Br J Cancer
Title: MTOR inhibitor-based combination therapies for pancreatic cancer.
Volume: 118
Issue: 3
Pages: 366-377
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: human
Publication
First Author: Morran DC
Year: 2014
Journal: Gut
Title: Targeting mTOR dependency in pancreatic cancer.
Volume: 63
Issue: 9
Pages: 1481-9
Publication
First Author: Ge MK
Year: 2023
Journal: Cell Metab
Title: The tRNA-GCN2-FBXO22-axis-mediated mTOR ubiquitination senses amino acid insufficiency.
Volume: 35
Issue: 12
Pages: 2216-2230.e8
Publication
First Author: Narita M
Year: 2011
Journal: Science
Title: Spatial coupling of mTOR and autophagy augments secretory phenotypes.
Volume: 332
Issue: 6032
Pages: 966-70
Publication
First Author: Jiao L
Year: 2021
Journal: J Pathol
Title: Deletion of mTOR in liver epithelial cells enhances hepatic metastasis of colon cancer.
Volume: 255
Issue: 3
Pages: 270-284
Publication
First Author: Jia J
Year: 2018
Journal: Mol Cell
Title: Galectins Control mTOR in Response to Endomembrane Damage.
Volume: 70
Issue: 1
Pages: 120-135.e8
Publication
First Author: Smithson LJ
Year: 2016
Journal: Genes Dev
Title: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Volume: 30
Issue: 12
Pages: 1383-8
Publication
First Author: Bulut-Karslioglu A
Year: 2016
Journal: Nature
Title: Inhibition of mTOR induces a paused pluripotent state.
Volume: 540
Issue: 7631
Pages: 119-123
Publication
First Author: Guo F
Year: 2013
Journal: Leukemia
Title: mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells.
Volume: 27
Issue: 10
Pages: 2040-2046
Publication
First Author: Düvel K
Year: 2010
Journal: Mol Cell
Title: Activation of a metabolic gene regulatory network downstream of mTOR complex 1.
Volume: 39
Issue: 2
Pages: 171-83
Publication
First Author: Gangloff YG
Year: 2004
Journal: Mol Cell Biol
Title: Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.
Volume: 24
Issue: 21
Pages: 9508-16
Publication
First Author: Zhu C
Year: 2018
Journal: Sci Rep
Title: mTOR complexes differentially orchestrates eosinophil development in allergy.
Volume: 8
Issue: 1
Pages: 6883
Publication
First Author: Chen R
Year: 2017
Journal: Oncogene
Title: mTOR promotes pituitary tumor development through activation of PTTG1.
Volume: 36
Issue: 7
Pages: 979-988
Publication
First Author: Cinà DP
Year: 2012
Journal: J Am Soc Nephrol
Title: Inhibition of MTOR disrupts autophagic flux in podocytes.
Volume: 23
Issue: 3
Pages: 412-20
Publication
First Author: Terenzio M
Year: 2018
Journal: Science
Title: Locally translated mTOR controls axonal local translation in nerve injury.
Volume: 359
Issue: 6382
Pages: 1416-1421
Publication
First Author: Li R
Year: 2017
Journal: Cancer Res
Title: Modulation of Bax and mTOR for Cancer Therapeutics.
Volume: 77
Issue: 11
Pages: 3001-3012
Publication
First Author: Chen F
Year: 2016
Journal: J Immunol
Title: mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production.
Volume: 196
Issue: 10
Pages: 4390-9
Publication
First Author: Yu J
Year: 2011
Journal: PLoS One
Title: mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
Volume: 6
Issue: 7
Pages: e21415
Publication  
First Author: Shan L
Year: 2016
Journal: Sci Rep
Title: mTOR Overactivation in Mesenchymal cells Aggravates CCl4- Induced liver Fibrosis.
Volume: 6
Pages: 36037
Publication
First Author: Pan X
Year: 2020
Journal: FASEB J
Title: Accumulation of prelamin A induces premature aging through mTOR overactivation.
Volume: 34
Issue: 6
Pages: 7905-7914
Publication
First Author: Tokumura K
Year: 2020
Journal: Biochem Biophys Res Commun
Title: mTOR regulates skeletogenesis through canonical and noncanonical pathways.
Volume: 533
Issue: 1
Pages: 30-35
Publication
First Author: Carr TD
Year: 2012
Journal: Cancer Prev Res (Phila)
Title: Inhibition of mTOR suppresses UVB-induced keratinocyte proliferation and survival.
Volume: 5
Issue: 12
Pages: 1394-404
Publication
First Author: Aoyagi T
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac mTOR protects the heart against ischemia-reperfusion injury.
Volume: 303
Issue: 1
Pages: H75-85
Publication
First Author: Liu D
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.
Volume: 115
Issue: 14
Pages: E3296-E3304
Publication
First Author: Gorentla BK
Year: 2011
Journal: Blood
Title: Negative regulation of mTOR activation by diacylglycerol kinases.
Volume: 117
Issue: 15
Pages: 4022-31
Publication
First Author: Khapre RV
Year: 2014
Journal: Aging (Albany NY)
Title: BMAL1-dependent regulation of the mTOR signaling pathway delays aging.
Volume: 6
Issue: 1
Pages: 48-57
Publication
First Author: Castilho RM
Year: 2009
Journal: Cell Stem Cell
Title: mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Volume: 5
Issue: 3
Pages: 279-89
Publication
First Author: Chen C
Year: 2009
Journal: Sci Signal
Title: mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Volume: 2
Issue: 98
Pages: ra75
Publication
First Author: Mori H
Year: 2009
Journal: Cell Metab
Title: Critical role for hypothalamic mTOR activity in energy balance.
Volume: 9
Issue: 4
Pages: 362-74
Publication
First Author: Liu Y
Year: 2013
Journal: Aging (Albany NY)
Title: Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development.
Volume: 5
Issue: 2
Pages: 111-9
Publication
First Author: Xu Z
Year: 2019
Journal: Adipocyte
Title: Elucidating the role of Lkb1 and mTOR in adipose tissue.
Volume: 8
Issue: 1
Pages: 26-30
Publication
First Author: Sampson LL
Year: 2016
Journal: FASEB J
Title: mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice.
Volume: 30
Issue: 3
Pages: 1263-75
Publication
First Author: Shende P
Year: 2016
Journal: Cardiovasc Res
Title: Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
Volume: 109
Issue: 1
Pages: 103-14
Publication
First Author: Bao Y
Year: 2015
Journal: J Cell Biol
Title: mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.
Volume: 210
Issue: 7
Pages: 1153-64
Publication
First Author: Wu M
Year: 2015
Journal: Oncotarget
Title: Flcn-deficient renal cells are tumorigenic and sensitive to mTOR suppression.
Volume: 6
Issue: 32
Pages: 32761-73
Publication
First Author: Ka M
Year: 2014
Journal: Development
Title: mTOR regulates brain morphogenesis by mediating GSK3 signaling.
Volume: 141
Issue: 21
Pages: 4076-86
Publication
First Author: Jones DD
Year: 2016
Journal: J Clin Invest
Title: mTOR has distinct functions in generating versus sustaining humoral immunity.
Volume: 126
Issue: 11
Pages: 4250-4261
Publication
First Author: Wang A
Year: 2017
Journal: Sci Rep
Title: Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.
Volume: 7
Issue: 1
Pages: 3005
Publication
First Author: Park IH
Year: 2005
Journal: Exp Cell Res
Title: Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.
Volume: 309
Issue: 1
Pages: 211-9
Publication
First Author: Buller CL
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: GLUT1 enhances mTOR activity independently of TSC2 and AMPK.
Volume: 301
Issue: 3
Pages: F588-96
Publication
First Author: Ganley IG
Year: 2009
Journal: J Biol Chem
Title: ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.
Volume: 284
Issue: 18
Pages: 12297-305
Publication    
First Author: Li J
Year: 2019
Journal: JCI Insight
Title: Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.
Volume: 5
Publication
First Author: Zhang S
Year: 2013
Journal: J Immunol
Title: B cell-specific deficiencies in mTOR limit humoral immune responses.
Volume: 191
Issue: 4
Pages: 1692-703
Publication
First Author: Rinaldi L
Year: 2017
Journal: Cell Death Dis
Title: Mitochondrial AKAP1 supports mTOR pathway and tumor growth.
Volume: 8
Issue: 6
Pages: e2842
Publication
First Author: Limon JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.
Volume: 111
Issue: 47
Pages: E5076-85
Publication
First Author: Li Z
Year: 2017
Journal: FASEB J
Title: mTOR activation protects liver from ischemia/reperfusion-induced injury through NF-κB pathway.
Volume: 31
Issue: 7
Pages: 3018-3026
Publication
First Author: Cybulski N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: mTOR complex 2 in adipose tissue negatively controls whole-body growth.
Volume: 106
Issue: 24
Pages: 9902-7
Publication
First Author: Takahashi Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes.
Volume: 417
Issue: 4
Pages: 1151-7
Publication
First Author: Baskaran P
Year: 2023
Journal: J Biol Chem
Title: Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis.
Volume: 299
Issue: 1
Pages: 102788
Publication
First Author: Li G
Year: 2020
Journal: J Clin Invest
Title: Chronic mTOR activation induces a degradative smooth muscle cell phenotype.
Volume: 130
Issue: 3
Pages: 1233-1251
Publication
First Author: Fujishita T
Year: 2017
Journal: Oncogene
Title: Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma.
Volume: 36
Issue: 46
Pages: 6480-6489
Publication
First Author: Dai J
Year: 2014
Journal: Glia
Title: Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.
Volume: 62
Issue: 12
Pages: 2096-109
Publication
First Author: Subramaniam S
Year: 2011
Journal: Nat Neurosci
Title: Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Volume: 15
Issue: 2
Pages: 191-3
Publication
First Author: Zhu Y
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α.
Volume: 305
Issue: 1
Pages: H41-51
Publication
First Author: Delgoffe GM
Year: 2011
Journal: Nat Immunol
Title: The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Volume: 12
Issue: 4
Pages: 295-303
Publication
First Author: Sinagoga KL
Year: 2017
Journal: Development
Title: Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Volume: 144
Issue: 13
Pages: 2402-2414
Publication
First Author: Santini E
Year: 2009
Journal: Sci Signal
Title: Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Volume: 2
Issue: 80
Pages: ra36
Publication
First Author: Shen C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: The mTOR pathway negatively controls ATM by up-regulating miRNAs.
Volume: 110
Issue: 29
Pages: 11869-74
Publication
First Author: Ka M
Year: 2017
Journal: Autophagy
Title: MTOR controls genesis and autophagy of GABAergic interneurons during brain development.
Volume: 13
Issue: 8
Pages: 1348-1363
Publication
First Author: Kamano Y
Year: 2013
Journal: FEBS Lett
Title: PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription.
Volume: 587
Issue: 20
Pages: 3303-8