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Search results 1 to 100 out of 2891 for Mtor

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Acosta-Jaquez HA
Year: 2009
Journal: Mol Cell Biol
Title: Site-specific mTOR phosphorylation promotes mTORC1-mediated signaling and cell growth.
Volume: 29
Issue: 15
Pages: 4308-24
Publication
First Author: Cunningham JT
Year: 2007
Journal: Nature
Title: mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex.
Volume: 450
Issue: 7170
Pages: 736-40
Publication
First Author: Ramanathan C
Year: 2018
Journal: PLoS Genet
Title: mTOR signaling regulates central and peripheral circadian clock function.
Volume: 14
Issue: 5
Pages: e1007369
Publication  
First Author: Scheffler JM
Year: 2014
Journal: Nat Commun
Title: LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.
Volume: 5
Pages: 5138
Publication
First Author: Meffre J
Year: 2012
Journal: EMBO Mol Med
Title: 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.
Volume: 4
Issue: 10
Pages: 1043-56
Publication
First Author: Shiota C
Year: 2006
Journal: Dev Cell
Title: Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability.
Volume: 11
Issue: 4
Pages: 583-9
Publication
First Author: Kim J
Year: 2011
Journal: Nat Cell Biol
Title: AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1.
Volume: 13
Issue: 2
Pages: 132-41
Publication
First Author: Takai H
Year: 2010
Journal: Genes Dev
Title: Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.
Volume: 24
Issue: 18
Pages: 2019-30
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Guertin DA
Year: 2009
Journal: Cancer Cell
Title: mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.
Volume: 15
Issue: 2
Pages: 148-59
Publication  
First Author: Ramalingam P
Year: 2020
Journal: J Exp Med
Title: Endothelial mTOR maintains hematopoiesis during aging.
Volume: 217
Issue: 6
Publication
First Author: Nardella C
Year: 2009
Journal: Sci Signal
Title: Differential requirement of mTOR in postmitotic tissues and tumorigenesis.
Volume: 2
Issue: 55
Pages: ra2
Publication
First Author: Guo F
Year: 2013
Journal: Haematologica
Title: Mouse gene targeting reveals an essential role of mTOR in hematopoietic stem cell engraftment and hematopoiesis.
Volume: 98
Issue: 9
Pages: 1353-8
Publication
First Author: Bayeva M
Year: 2012
Journal: Cell Metab
Title: mTOR regulates cellular iron homeostasis through tristetraprolin.
Volume: 16
Issue: 5
Pages: 645-57
Publication
First Author: Hassan Z
Year: 2018
Journal: Br J Cancer
Title: MTOR inhibitor-based combination therapies for pancreatic cancer.
Volume: 118
Issue: 3
Pages: 366-377
Publication
First Author: Guertin DA
Year: 2006
Journal: Dev Cell
Title: Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.
Volume: 11
Issue: 6
Pages: 859-71
Publication
First Author: Narita M
Year: 2011
Journal: Science
Title: Spatial coupling of mTOR and autophagy augments secretory phenotypes.
Volume: 332
Issue: 6032
Pages: 966-70
Publication
First Author: Smithson LJ
Year: 2016
Journal: Genes Dev
Title: Proteomic analysis reveals GIT1 as a novel mTOR complex component critical for mediating astrocyte survival.
Volume: 30
Issue: 12
Pages: 1383-8
Publication
First Author: Jia J
Year: 2018
Journal: Mol Cell
Title: Galectins Control mTOR in Response to Endomembrane Damage.
Volume: 70
Issue: 1
Pages: 120-135.e8
Publication
First Author: Bulut-Karslioglu A
Year: 2016
Journal: Nature
Title: Inhibition of mTOR induces a paused pluripotent state.
Volume: 540
Issue: 7631
Pages: 119-123
Publication
First Author: Guo F
Year: 2013
Journal: Leukemia
Title: mTOR regulates DNA damage response through NF-κB-mediated FANCD2 pathway in hematopoietic cells.
Volume: 27
Issue: 10
Pages: 2040-2046
Publication
First Author: Zhu C
Year: 2018
Journal: Sci Rep
Title: mTOR complexes differentially orchestrates eosinophil development in allergy.
Volume: 8
Issue: 1
Pages: 6883
Publication
First Author: Gangloff YG
Year: 2004
Journal: Mol Cell Biol
Title: Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development.
Volume: 24
Issue: 21
Pages: 9508-16
Publication
First Author: Cinà DP
Year: 2012
Journal: J Am Soc Nephrol
Title: Inhibition of MTOR disrupts autophagic flux in podocytes.
Volume: 23
Issue: 3
Pages: 412-20
Publication
First Author: Terenzio M
Year: 2018
Journal: Science
Title: Locally translated mTOR controls axonal local translation in nerve injury.
Volume: 359
Issue: 6382
Pages: 1416-1421
Publication
First Author: Sampson LL
Year: 2016
Journal: FASEB J
Title: mTOR disruption causes intestinal epithelial cell defects and intestinal atrophy postinjury in mice.
Volume: 30
Issue: 3
Pages: 1263-75
Publication
First Author: Li R
Year: 2017
Journal: Cancer Res
Title: Modulation of Bax and mTOR for Cancer Therapeutics.
Volume: 77
Issue: 11
Pages: 3001-3012
Publication
First Author: Yu J
Year: 2011
Journal: PLoS One
Title: mTOR controls ovarian follicle growth by regulating granulosa cell proliferation.
Volume: 6
Issue: 7
Pages: e21415
Publication
First Author: Aoyagi T
Year: 2012
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac mTOR protects the heart against ischemia-reperfusion injury.
Volume: 303
Issue: 1
Pages: H75-85
Publication  
First Author: Shan L
Year: 2016
Journal: Sci Rep
Title: mTOR Overactivation in Mesenchymal cells Aggravates CCl4- Induced liver Fibrosis.
Volume: 6
Pages: 36037
Publication
First Author: Liu Y
Year: 2013
Journal: Aging (Albany NY)
Title: Temporal mTOR inhibition protects Fbxw7-deficient mice from radiation-induced tumor development.
Volume: 5
Issue: 2
Pages: 111-9
Publication
First Author: Shende P
Year: 2016
Journal: Cardiovasc Res
Title: Cardiac mTOR complex 2 preserves ventricular function in pressure-overload hypertrophy.
Volume: 109
Issue: 1
Pages: 103-14
Publication
First Author: Liu D
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: mTOR signaling in VIP neurons regulates circadian clock synchrony and olfaction.
Volume: 115
Issue: 14
Pages: E3296-E3304
Publication
First Author: Gorentla BK
Year: 2011
Journal: Blood
Title: Negative regulation of mTOR activation by diacylglycerol kinases.
Volume: 117
Issue: 15
Pages: 4022-31
Publication
First Author: Khapre RV
Year: 2014
Journal: Aging (Albany NY)
Title: BMAL1-dependent regulation of the mTOR signaling pathway delays aging.
Volume: 6
Issue: 1
Pages: 48-57
Publication
First Author: Chen C
Year: 2009
Journal: Sci Signal
Title: mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells.
Volume: 2
Issue: 98
Pages: ra75
Publication
First Author: Mori H
Year: 2009
Journal: Cell Metab
Title: Critical role for hypothalamic mTOR activity in energy balance.
Volume: 9
Issue: 4
Pages: 362-74
Publication
First Author: Castilho RM
Year: 2009
Journal: Cell Stem Cell
Title: mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging.
Volume: 5
Issue: 3
Pages: 279-89
Publication
First Author: Xu Z
Year: 2019
Journal: Adipocyte
Title: Elucidating the role of Lkb1 and mTOR in adipose tissue.
Volume: 8
Issue: 1
Pages: 26-30
Publication
First Author: Jones DD
Year: 2016
Journal: J Clin Invest
Title: mTOR has distinct functions in generating versus sustaining humoral immunity.
Volume: 126
Issue: 11
Pages: 4250-4261
Publication
First Author: Park IH
Year: 2005
Journal: Exp Cell Res
Title: Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1.
Volume: 309
Issue: 1
Pages: 211-9
Publication
First Author: Bao Y
Year: 2015
Journal: J Cell Biol
Title: mTOR and differential activation of mitochondria orchestrate neutrophil chemotaxis.
Volume: 210
Issue: 7
Pages: 1153-64
Publication
First Author: Ganley IG
Year: 2009
Journal: J Biol Chem
Title: ULK1.ATG13.FIP200 complex mediates mTOR signaling and is essential for autophagy.
Volume: 284
Issue: 18
Pages: 12297-305
Publication
First Author: Ka M
Year: 2014
Journal: Development
Title: mTOR regulates brain morphogenesis by mediating GSK3 signaling.
Volume: 141
Issue: 21
Pages: 4076-86
Publication
First Author: Limon JJ
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: mTOR kinase inhibitors promote antibody class switching via mTORC2 inhibition.
Volume: 111
Issue: 47
Pages: E5076-85
Publication
First Author: Wang A
Year: 2017
Journal: Sci Rep
Title: Activity-independent targeting of mTOR to lysosomes in primary osteoclasts.
Volume: 7
Issue: 1
Pages: 3005
Publication
First Author: Buller CL
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: GLUT1 enhances mTOR activity independently of TSC2 and AMPK.
Volume: 301
Issue: 3
Pages: F588-96
Publication    
First Author: Li J
Year: 2019
Journal: JCI Insight
Title: Myeloid Folliculin balances mTOR activation to maintain innate immunity homeostasis.
Volume: 5
Publication
First Author: Delgoffe GM
Year: 2011
Journal: Nat Immunol
Title: The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2.
Volume: 12
Issue: 4
Pages: 295-303
Publication
First Author: Cybulski N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: mTOR complex 2 in adipose tissue negatively controls whole-body growth.
Volume: 106
Issue: 24
Pages: 9902-7
Publication
First Author: Li Z
Year: 2017
Journal: FASEB J
Title: mTOR activation protects liver from ischemia/reperfusion-induced injury through NF-κB pathway.
Volume: 31
Issue: 7
Pages: 3018-3026
Publication
First Author: Zhang S
Year: 2013
Journal: J Immunol
Title: B cell-specific deficiencies in mTOR limit humoral immune responses.
Volume: 191
Issue: 4
Pages: 1692-703
Publication
First Author: Fujishita T
Year: 2017
Journal: Oncogene
Title: Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma.
Volume: 36
Issue: 46
Pages: 6480-6489
Publication
First Author: Dai J
Year: 2014
Journal: Glia
Title: Interaction of mTOR and Erk1/2 signaling to regulate oligodendrocyte differentiation.
Volume: 62
Issue: 12
Pages: 2096-109
Publication
First Author: Takahashi Y
Year: 2012
Journal: Biochem Biophys Res Commun
Title: The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes.
Volume: 417
Issue: 4
Pages: 1151-7
Publication
First Author: Subramaniam S
Year: 2011
Journal: Nat Neurosci
Title: Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia.
Volume: 15
Issue: 2
Pages: 191-3
Publication
First Author: Zhu Y
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α.
Volume: 305
Issue: 1
Pages: H41-51
Publication
First Author: Sinagoga KL
Year: 2017
Journal: Development
Title: Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.
Volume: 144
Issue: 13
Pages: 2402-2414
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Santini E
Year: 2009
Journal: Sci Signal
Title: Inhibition of mTOR signaling in Parkinson's disease prevents L-DOPA-induced dyskinesia.
Volume: 2
Issue: 80
Pages: ra36
Publication
First Author: Ka M
Year: 2017
Journal: Autophagy
Title: MTOR controls genesis and autophagy of GABAergic interneurons during brain development.
Volume: 13
Issue: 8
Pages: 1348-1363
Publication
First Author: Kamano Y
Year: 2013
Journal: FEBS Lett
Title: PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription.
Volume: 587
Issue: 20
Pages: 3303-8
Publication
First Author: Shen C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: The mTOR pathway negatively controls ATM by up-regulating miRNAs.
Volume: 110
Issue: 29
Pages: 11869-74
Publication
First Author: Zhang S
Year: 2011
Journal: Blood
Title: Constitutive reductions in mTOR alter cell size, immune cell development, and antibody production.
Volume: 117
Issue: 4
Pages: 1228-38
Publication  
First Author: Raman L
Year: 2013
Journal: Neurosci Lett
Title: Pharmacological inhibition of the mTOR pathway impairs hippocampal development in mice.
Volume: 541
Pages: 9-14
Publication
First Author: Delgoffe GM
Year: 2009
Journal: Immunity
Title: The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment.
Volume: 30
Issue: 6
Pages: 832-44
Publication
First Author: Sintes J
Year: 2017
Journal: Nat Commun
Title: mTOR intersects antibody-inducing signals from TACI in marginal zone B cells.
Volume: 8
Issue: 1
Pages: 1462
Publication
First Author: Ferrara-Romeo I
Year: 2020
Journal: Nat Commun
Title: The mTOR pathway is necessary for survival of mice with short telomeres.
Volume: 11
Issue: 1
Pages: 1168
Publication
First Author: Mao JH
Year: 2008
Journal: Science
Title: FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression.
Volume: 321
Issue: 5895
Pages: 1499-502
Publication
First Author: Huynh H
Year: 2017
Journal: Cell Rep
Title: mTOR Inhibition Subdues Milk Disorder Caused by Maternal VLDLR Loss.
Volume: 19
Issue: 10
Pages: 2014-2025
Publication
First Author: Li Z
Year: 2017
Journal: Cell Death Differ
Title: miR-199a impairs autophagy and induces cardiac hypertrophy through mTOR activation.
Volume: 24
Issue: 7
Pages: 1205-1213
Publication
First Author: Gödel M
Year: 2011
Journal: J Clin Invest
Title: Role of mTOR in podocyte function and diabetic nephropathy in humans and mice.
Volume: 121
Issue: 6
Pages: 2197-209
Publication
First Author: Hsieh AC
Year: 2012
Journal: Nature
Title: The translational landscape of mTOR signalling steers cancer initiation and metastasis.
Volume: 485
Issue: 7396
Pages: 55-61
Publication
First Author: Puighermanal E
Year: 2009
Journal: Nat Neurosci
Title: Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling.
Volume: 12
Issue: 9
Pages: 1152-8
Publication
First Author: Kuo HP
Year: 2010
Journal: Sci Signal
Title: ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.
Volume: 3
Issue: 108
Pages: ra9
Publication
First Author: Gui YS
Year: 2015
Journal: PLoS One
Title: mTOR Overactivation and Compromised Autophagy in the Pathogenesis of Pulmonary Fibrosis.
Volume: 10
Issue: 9
Pages: e0138625
Publication
First Author: Cang C
Year: 2013
Journal: Cell
Title: mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state.
Volume: 152
Issue: 4
Pages: 778-790
Publication
First Author: Wang S
Year: 2015
Journal: PLoS Biol
Title: Insulin and mTOR Pathway Regulate HDAC3-Mediated Deacetylation and Activation of PGK1.
Volume: 13
Issue: 9
Pages: e1002243
Publication
First Author: Partovian C
Year: 2008
Journal: Mol Cell
Title: Syndecan-4 regulates subcellular localization of mTOR Complex2 and Akt activation in a PKCalpha-dependent manner in endothelial cells.
Volume: 32
Issue: 1
Pages: 140-9
Publication
First Author: Risson V
Year: 2009
Journal: J Cell Biol
Title: Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy.
Volume: 187
Issue: 6
Pages: 859-74
Publication
First Author: Alejandro EU
Year: 2014
Journal: J Clin Invest
Title: Maternal diet-induced microRNAs and mTOR underlie β cell dysfunction in offspring.
Volume: 124
Issue: 10
Pages: 4395-410
Publication
First Author: Marhold M
Year: 2015
Journal: Mol Cancer Res
Title: HIF1α Regulates mTOR Signaling and Viability of Prostate Cancer Stem Cells.
Volume: 13
Issue: 3
Pages: 556-64
Publication
First Author: Uddin MN
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation.
Volume: 407
Issue: 4
Pages: 692-8
Publication
First Author: Li Z
Year: 2019
Journal: Hepatology
Title: mTOR Signaling in X/A-Like Cells Contributes to Lipid Homeostasis in Mice.
Volume: 69
Issue: 2
Pages: 860-875
Publication
First Author: Dominick G
Year: 2015
Journal: Endocrinology
Title: Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.
Volume: 156
Issue: 2
Pages: 565-75
Publication
First Author: Squarize CH
Year: 2010
Journal: PLoS One
Title: Accelerated wound healing by mTOR activation in genetically defined mouse models.
Volume: 5
Issue: 5
Pages: e10643