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Search results 1 to 100 out of 272 for Mttp

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Hits by Strain

Type Details Score
Gene
4547 | MTTP
Type: gene
Organism: human
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Gene
100487453 | mttp
Type: gene
Organism: frog, western clawed
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Gene
key_28633 | MTTP
Type: gene
Organism: hamster, golden
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Gene
310900 | Mttp
Type: gene
Organism: rat
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Gene
487873 | MTTP
Type: gene
Organism: dog, domestic
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Gene
471397 | MTTP
Type: gene
Organism: chimpanzee
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Gene
280868 | MTTP
Type: gene
Organism: cattle
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Gene
422709 | MTTP
Type: gene
Organism: chicken
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Gene
406207 | mttp
Type: gene
Organism: zebrafish
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Gene
708832 | MTTP
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR039988 | MTTP
Type: Family
Description: Microsomal triglyceride transfer protein large subunit (MTTP) catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces, and is required for the secretion of plasma lipoproteins that contain apolipoprotein B. It is a heterodimer consisting of a large MTP alpha-subunit and a protein disulfide isomerase (PDI) beta-subunit. Mutations in microsomal triglyceride transfer protein (MTP) cause abetalipoproteinemia [, , ].
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Protein Coding Gene
MGI:106926 | Mttp
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24474819 | J:208783
First Author: Xie Y
Year: 2014
Journal: J Lipid Res
Title: Hepatic Mttp deletion reverses gallstone susceptibility in L-Fabp knockout mice.
Volume: 55
Issue: 3
Pages: 540-8
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Publication
16354657 | J:108489
First Author: Xie Y
Year: 2006
Journal: J Biol Chem
Title: Compensatory increase in hepatic lipogenesis in mice with conditional intestine-specific Mttp deficiency.
Volume: 281
Issue: 7
Pages: 4075-86
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Publication
38211723 | J:345662
 
First Author: Chen Z
Year: 2024
Journal: Mol Metab
Title: Conditional hepatocyte ablation of PDIA1 uncovers indispensable roles in both APOB and MTTP folding to support VLDL secretion.
Volume: 80
Pages: 101874
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Publication
23145105 | J:194796
First Author: Dominguez JA
Year: 2012
Journal: PLoS One
Title: Intestine-specific Mttp deletion decreases mortality and prevents sepsis-induced intestinal injury in a murine model of Pseudomonas aeruginosa pneumonia.
Volume: 7
Issue: 11
Pages: e49159
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Protein
O08601
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: false
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Protein
Q3UWK4
Organism: Mus musculus/domesticus
Length: 479  
Fragment?: true
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Publication
23805328 | J:204352
First Author: Xie Y
Year: 2013
Journal: PLoS One
Title: Intestine-Specific Mttp Deletion Increases the Severity of Experimental Colitis and Leads to Greater Tumor Burden in a Model of Colitis Associated Cancer.
Volume: 8
Issue: 6
Pages: e67819
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Protein
Q3TVF2
Organism: Mus musculus/domesticus
Length: 199  
Fragment?: true
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Publication
23475612 | -
First Author: Khatun I
Year: 2013
Journal: J Lipid Res
Title: Loss of both phospholipid and triglyceride transfer activities of microsomal triglyceride transfer protein in abetalipoproteinemia.
Volume: 54
Issue: 6
Pages: 1541-9
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Publication
8939939 | -
First Author: Rehberg EF
Year: 1996
Journal: J Biol Chem
Title: A novel abetalipoproteinemia genotype. Identification of a missense mutation in the 97-kDa subunit of the microsomal triglyceride transfer protein that prevents complex formation with protein disulfide isomerase.
Volume: 271
Issue: 47
Pages: 29945-52
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Publication
26224785 | -
First Author: Walsh MT
Year: 2015
Journal: Circ Cardiovasc Genet
Title: Novel Abetalipoproteinemia Missense Mutation Highlights the Importance of the N-Terminal β-Barrel in Microsomal Triglyceride Transfer Protein Function.
Volume: 8
Issue: 5
Pages: 677-87
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Publication
17064699 | J:124954
First Author: Amigo L
Year: 2006
Journal: Gastroenterology
Title: Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones.
Volume: 131
Issue: 6
Pages: 1870-8
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Publication
31533023 | J:293642
 
First Author: Klevstig M
Year: 2019
Journal: J Mol Cell Cardiol
Title: Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.
Volume: 137
Pages: 1-8
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Publication
18515909 | J:139765
First Author: Minehira K
Year: 2008
Journal: J Lipid Res
Title: Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice.
Volume: 49
Issue: 9
Pages: 2038-44
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Publication
38445789 | J:360749
First Author: Grubaugh CR
Year: 2024
Journal: FASEB J
Title: Microsomal triglyceride transfer protein is necessary to maintain lipid homeostasis and retinal function.
Volume: 38
Issue: 5
Pages: e23522
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Publication
31353085 | J:291782
First Author: Zhang S
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Identification of antisense transcripts of the microsomal triglyceride transfer protein genes in humans and mice.
Volume: 517
Issue: 2
Pages: 317-323
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Publication
10225972 | J:54612
First Author: Raabe M
Year: 1999
Journal: J Clin Invest
Title: Analysis of the role of microsomal triglyceride transfer protein in the liver of tissue-specific knockout mice.
Volume: 103
Issue: 9
Pages: 1287-98
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Publication
36053190 | J:344880
First Author: van Zwol W
Year: 2023
Journal: Hepatology
Title: Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.
Volume: 78
Issue: 5
Pages: 1418-1432
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Publication
17403933 | J:125608
First Author: Sagiv Y
Year: 2007
Journal: J Exp Med
Title: A distal effect of microsomal triglyceride transfer protein deficiency on the lysosomal recycling of CD1d.
Volume: 204
Issue: 4
Pages: 921-8
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Publication
33168624 | J:306883
     
First Author: Peng H
Year: 2020
Journal: J Biol Chem
Title: PRAP1 is a novel lipid binding protein that promotes lipid absorption by facilitating MTTP-mediated lipid transport.
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Publication
17855359 | J:126942
First Author: Xie Y
Year: 2007
Journal: J Biol Chem
Title: Conditional intestinal lipotoxicity in Apobec-1-/- Mttp-IKO mice: a survival advantage for mammalian intestinal apolipoprotein B mRNA editing.
Volume: 282
Issue: 45
Pages: 33043-51
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Publication
24353284 | J:216037
First Author: Wang F
Year: 2014
Journal: J Mol Endocrinol
Title: LGR4 acts as a link between the peripheral circadian clock and lipid metabolism in liver.
Volume: 52
Issue: 2
Pages: 133-43
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Publication
24019513 | J:204909
First Author: Iqbal J
Year: 2013
Journal: J Biol Chem
Title: Lipid absorption defects in intestine-specific microsomal triglyceride transfer protein and ATP-binding cassette transporter A1-deficient mice.
Volume: 288
Issue: 42
Pages: 30432-44
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Publication
15107843 | J:99596
First Author: Brozovic S
Year: 2004
Journal: Nat Med
Title: CD1d function is regulated by microsomal triglyceride transfer protein.
Volume: 10
Issue: 5
Pages: 535-9
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Publication
14583618 | J:124544
First Author: Larsson SL
Year: 2004
Journal: J Biol Chem
Title: The low density lipoprotein receptor prevents secretion of dense apoB100-containing lipoproteins from the liver.
Volume: 279
Issue: 2
Pages: 831-6
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Publication
12628954 | J:91722
First Author: Lieu HD
Year: 2003
Journal: Circulation
Title: Eliminating atherogenesis in mice by switching off hepatic lipoprotein secretion.
Volume: 107
Issue: 9
Pages: 1315-21
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Publication
19433756 | J:166428
First Author: Miller JD
Year: 2009
Journal: Circulation
Title: Lowering plasma cholesterol levels halts progression of aortic valve disease in mice.
Volume: 119
Issue: 20
Pages: 2693-701
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Publication
24586211 | J:211003
First Author: Björkegren JL
Year: 2014
Journal: PLoS Genet
Title: Plasma cholesterol-induced lesion networks activated before regression of early, mature, and advanced atherosclerosis.
Volume: 10
Issue: 2
Pages: e1004201
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Publication
18519977 | J:139764
First Author: Chen Z
Year: 2008
Journal: J Lipid Res
Title: ApoB100 is required for increased VLDL-triglyceride secretion by microsomal triglyceride transfer protein in ob/ob mice.
Volume: 49
Issue: 9
Pages: 2013-22
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Protein Coding Gene
MGP_CAROLIEiJ_G0025675 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027881 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027893 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_106926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028337 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027600 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027739 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027706 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027849 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0027738 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0028395 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0026803 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027158 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027124 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0026630 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8660984 | J:32784
First Author: Nakamuta M
Year: 1996
Journal: Genomics
Title: Mouse microsomal triglyceride transfer protein large subunit: cDNA cloning, tissue-specific expression and chromosomal localization.
Volume: 33
Issue: 2
Pages: 313-6
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Publication
17312007 | J:125365
First Author: Dougan SK
Year: 2007
Journal: J Exp Med
Title: MTP regulated by an alternate promoter is essential for NKT cell development.
Volume: 204
Issue: 3
Pages: 533-45
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Publication
15897609 | J:296129
First Author: Rava P
Year: 2005
Journal: J Lipid Res
Title: Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein.
Volume: 46
Issue: 8
Pages: 1779-85
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Publication
16478722 | J:296130
First Author: Rava P
Year: 2006
Journal: J Biol Chem
Title: Phospholipid transfer activity of microsomal triacylglycerol transfer protein is sufficient for the assembly and secretion of apolipoprotein B lipoproteins.
Volume: 281
Issue: 16
Pages: 11019-27
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Publication
17635917 | J:124933
First Author: Mohler PJ
Year: 2007
Journal: J Biol Chem
Title: Identification of a novel isoform of microsomal triglyceride transfer protein.
Volume: 282
Issue: 37
Pages: 26981-8
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Publication
9671739 | J:48934
First Author: Raabe M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes.
Volume: 95
Issue: 15
Pages: 8686-91
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Publication
17582142 | J:125237
First Author: Anwar K
Year: 2007
Journal: J Lipid Res
Title: Mechanisms involved in vitamin E transport by primary enterocytes and in vivo absorption.
Volume: 48
Issue: 9
Pages: 2028-38
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Publication
29754800 | J:263839
First Author: Haider A
Year: 2018
Journal: Dev Cell
Title: PCYT1A Regulates Phosphatidylcholine Homeostasis from the Inner Nuclear Membrane in Response to Membrane Stored Curvature Elastic Stress.
Volume: 45
Issue: 4
Pages: 481-495.e8
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Publication
24511105 | J:210163
First Author: Dikkers A
Year: 2014
Journal: J Lipid Res
Title: Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice.
Volume: 55
Issue: 5
Pages: 816-25
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Publication
16710047 | J:112587
First Author: Minehira-Castelli K
Year: 2006
Journal: J Lipid Res
Title: Absence of VLDL secretion does not affect alpha-tocopherol content in peripheral tissues.
Volume: 47
Issue: 8
Pages: 1733-8
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Publication
22121032 | J:210793
First Author: Khatun I
Year: 2012
Journal: Hepatology
Title: Phospholipid transfer activity of microsomal triglyceride transfer protein produces apolipoprotein B and reduces hepatosteatosis while maintaining low plasma lipids in mice.
Volume: 55
Issue: 5
Pages: 1356-68
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Publication
12588952 | J:83459
First Author: Liao W
Year: 2003
Journal: J Lipid Res
Title: Blocking microsomal triglyceride transfer protein interferes with apoB secretion without causing retention or stress in the ER.
Volume: 44
Issue: 5
Pages: 978-85
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Publication
11739387 | J:74633
First Author: Björkegren J
Year: 2002
Journal: J Biol Chem
Title: Blocking the secretion of hepatic very low density lipoproteins renders the liver more susceptible to toxin-induced injury.
Volume: 277
Issue: 7
Pages: 5476-83
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Publication
20864669 | J:183146
First Author: Miller JD
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Evidence for active regulation of pro-osteogenic signaling in advanced aortic valve disease.
Volume: 30
Issue: 12
Pages: 2482-6
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Publication
28793320 | J:246367
First Author: Swift LL
Year: 2017
Journal: PLoS One
Title: Microsomal triglyceride transfer protein contributes to lipid droplet maturation in adipocytes.
Volume: 12
Issue: 8
Pages: e0181046
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Publication
10037685 | J:53390
First Author: Chang BH
Year: 1999
Journal: J Biol Chem
Title: Liver-specific inactivation of the abetalipoproteinemia gene completely abrogates very low density lipoprotein/low density lipoprotein production in a viable conditional knockout mouse.
Volume: 274
Issue: 10
Pages: 6051-5
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Publication
33730569 | J:332437
First Author: Anastasia I
Year: 2021
Journal: Cell Rep
Title: Mitochondria-rough-ER contacts in the liver regulate systemic lipid homeostasis.
Volume: 34
Issue: 11
Pages: 108873
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Publication
36228741 | J:330922
 
First Author: Rajan S
Year: 2022
Journal: Metabolism
Title: Microsomal triglyceride transfer protein regulates intracellular lipolysis in adipocytes independent of its lipid transfer activity.
Volume: 137
Pages: 155331
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Publication
15922333 | J:99785
First Author: Swift LL
Year: 2005
Journal: FEBS Lett
Title: Microsomal triglyceride transfer protein expression in adipocytes: a new component in fat metabolism.
Volume: 579
Issue: 14
Pages: 3183-9
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Pooled
Emaps: EMAPS:3604011
Stage: TS11
Assay Id: MGI:2671388
Age: embryonic day 7.5
Specimen Label: None
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608521
Stage: TS21
Assay Id: MGI:2671388
Age: embryonic day 13.5
Specimen Label: None
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2671388
Age: embryonic day 13.5
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:2671388
Age: embryonic day 13.5
Specimen Label: None
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608526
Stage: TS26
Assay Id: MGI:2671388
Age: embryonic day 18.5
Specimen Label: None
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2671388
Age: embryonic day 18.5
Specimen Label: None
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:2671248
Assay Type: RT-PCR
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684626
Stage: TS26
Assay Id: MGI:2671388
Age: embryonic day 18.5
Specimen Label: None
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Present
Sex: Pooled
Emaps: EMAPS:3604011
Stage: TS11
Assay Id: MGI:2671395
Age: embryonic day 7.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608521
Stage: TS21
Assay Id: MGI:2671395
Age: embryonic day 13.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Absent
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2671395
Age: embryonic day 13.5
Image: 1
Specimen Label: None
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:2671395
Age: embryonic day 13.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608526
Stage: TS26
Assay Id: MGI:2671395
Age: embryonic day 18.5
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Absent
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2671395
Age: embryonic day 18.5
Image: 1
Specimen Label: None
Detected: false
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2671395
Age: postnatal adult
Image: 1
Specimen Label: None
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
     
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2671395
Age: postnatal adult
Image: 1
Specimen Label: None
Specimen Num: 12
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GXD Expression
GXD Expression
     
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2671395
Age: postnatal adult
Image: 1
Specimen Label: None
Specimen Num: 13
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:2671256
Assay Type: RNase protection
Annotation Date: 2003-09-04
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2671395
Age: postnatal adult
Image: 1
Specimen Label: None
Specimen Num: 14
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2671263
Assay Type: Western blot
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608521
Stage: TS21
Assay Id: MGI:2671440
Age: embryonic day 13.5
Image: 3
Specimen Label: None
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2671263
Assay Type: Western blot
Annotation Date: 2003-09-04
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608521
Stage: TS21
Assay Id: MGI:2671440
Age: embryonic day 13.5
Image: 3
Specimen Label: None
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2671263
Assay Type: Western blot
Annotation Date: 2003-09-04
Strength: Absent
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2671440
Age: embryonic day 13.5
Image: 3
Specimen Label: None
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:2671263
Assay Type: Western blot
Annotation Date: 2003-09-04
Strength: Absent
Sex: Female
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:2671440
Age: embryonic day 13.5
Image: 3
Specimen Label: None
Detected: false
Specimen Num: 4
•
•
•
•
•




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