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Search results 1 to 100 out of 641 for Mtus1

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: This entry represents the microtubule-associated tumour suppressor (MTUS1) family, including AT2 receptor-interacting proteins (ATIPs) from mammals and Inner centromere Kin-I stimulator (ICIS) from Xenopus. The transcript variants of human MTUS1 gene can be classified into three major groups (ATIP1, ATIP3 and ATIP4) based on their tissue distribution and utilisation of its exons []. ATIP1, also known as MTSG1, interacts with the AT2 receptor and is involved in its activation. AT2 receptor could antagonise the effect of the AT1 receptor and generate anti-proliferative, anti-migratory and anti-inflammatory responses []. It may cooperate with AT2 to inactivate the receptor tyrosine kinases [].ATIP3 is a microtubule associated protein whose expression is diminished in breast cancer []. It localises at the mitotic spindle throughout mitosis and decorates the intercellular bridge during cytokinesis []. It is a homologue of the Xenopus ICIS protein, which is an inner centromere protein acting as a scaffold to bring the microtubule-depolymerising kinesins MCAK and Kif2A to the kinetochore []. ICIS may regulate kinesin depolymerase activity at the mitotic spindle and ensures proper chromosome segregation during mitosis []. ATIP4 may be involved in brain development and/or cognition [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 104  
Fragment?: true
Publication
First Author: Rodrigues-Ferreira S
Year: 2009
Journal: PLoS One
Title: 8p22 MTUS1 gene product ATIP3 is a novel anti-mitotic protein underexpressed in invasive breast carcinoma of poor prognosis.
Volume: 4
Issue: 10
Pages: e7239
Publication  
First Author: Wang Y
Year: 2016
Journal: J Mol Cell Cardiol
Title: MTUS1 silencing promotes E-selectin production through p38 MAPK-dependent CREB ubiquitination in endothelial cells.
Volume: 101
Pages: 1-10
Publication
First Author: Nouet S
Year: 2004
Journal: J Biol Chem
Title: Trans-inactivation of receptor tyrosine kinases by novel angiotensin II AT2 receptor-interacting protein, ATIP.
Volume: 279
Issue: 28
Pages: 28989-97
Protein
Organism: Mus musculus/domesticus
Length: 1210  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1210  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 520  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 759  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 440  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 214  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 230  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: true
Publication
First Author: Rodrigues-Ferreira S
Year: 2010
Journal: Trends Endocrinol Metab
Title: An ATIPical family of angiotensin II AT2 receptor-interacting proteins.
Volume: 21
Issue: 11
Pages: 684-90
Publication
First Author: Knowlton AL
Year: 2009
Journal: Curr Biol
Title: ICIS and Aurora B coregulate the microtubule depolymerase Kif2a.
Volume: 19
Issue: 9
Pages: 758-63
Publication
First Author: Di Benedetto M
Year: 2006
Journal: Gene
Title: Structural organization and expression of human MTUS1, a candidate 8p22 tumor suppressor gene encoding a family of angiotensin II AT2 receptor-interacting proteins, ATIP.
Volume: 380
Issue: 2
Pages: 127-36
Publication
First Author: Bundschu K
Year: 2014
Journal: Dev Dyn
Title: Cardiovascular ATIP (Angiotensin receptor type 2 interacting protein) expression in mouse development.
Volume: 243
Issue: 5
Pages: 699-711
Publication
First Author: Zuern C
Year: 2012
Journal: Int J Oncol
Title: Microtubule associated tumor suppressor 1 deficient mice develop spontaneous heart hypertrophy and SLE-like lymphoproliferative disease.
Volume: 40
Issue: 4
Pages: 1079-88
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jing F
Year: 2013
Journal: PLoS One
Title: Effect of angiotensin II type 2 receptor-interacting protein on adipose tissue function via modulation of macrophage polarization.
Volume: 8
Issue: 4
Pages: e60067
Publication
First Author: Fujita T
Year: 2009
Journal: Hypertension
Title: Attenuation of cuff-induced neointimal formation by overexpression of angiotensin II type 2 receptor-interacting protein 1.
Volume: 53
Issue: 4
Pages: 688-93
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603911
Stage: TS11
Assay Id: MGI:5688692
Age: embryonic day 7.5
Image: 9
Specimen Label: embryo
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608514
Stage: TS14
Assay Id: MGI:5688694
Age: embryonic day 8.5
Image: 9
Specimen Label: yolk sac
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608914
Stage: TS14
Assay Id: MGI:5688694
Age: embryonic day 8.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610514
Stage: TS14
Assay Id: MGI:5688694
Age: embryonic day 8.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1658014
Stage: TS14
Assay Id: MGI:5688694
Age: embryonic day 8.5
Image: 9
Specimen Label: tail
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608515
Stage: TS15
Assay Id: MGI:5688695
Age: embryonic day 9.5
Image: 9
Specimen Label: yolk sac
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608915
Stage: TS15
Assay Id: MGI:5688695
Age: embryonic day 9.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610515
Stage: TS15
Assay Id: MGI:5688695
Age: embryonic day 9.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674815
Stage: TS15
Assay Id: MGI:5688695
Age: embryonic day 9.5
Image: 9
Specimen Label: tail
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608517
Stage: TS17
Assay Id: MGI:5688696
Age: embryonic day 10.5
Image: 9
Specimen Label: yolk sac
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689417
Stage: TS17
Assay Id: MGI:5688696
Age: embryonic day 10.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610517
Stage: TS17
Assay Id: MGI:5688696
Age: embryonic day 10.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674817
Stage: TS17
Assay Id: MGI:5688696
Age: embryonic day 10.5
Image: 9
Specimen Label: tail tip
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619817
Stage: TS17
Assay Id: MGI:5688696
Age: embryonic day 10.5
Image: 9
Specimen Label: eye
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640517
Stage: TS17
Assay Id: MGI:5688696
Age: embryonic day 10.5
Image: 9
Specimen Label: limbs
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608519
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: yolk sac
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610519
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674819
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: tail tip
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619819
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: eye
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640519
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: limbs
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187319
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672819
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: lung
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684619
Stage: TS19
Assay Id: MGI:5688697
Age: embryonic day 11.5
Image: 9
Specimen Label: liver
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608520
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: yolk sac
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610520
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1674820
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: tail tip
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619820
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: eye
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640520
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: limbs
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187320
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672820
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: lung
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684620
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: liver
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2611520
Stage: TS20
Assay Id: MGI:5688698
Age: embryonic day 12.5
Image: 9
Specimen Label: u. cord
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608521
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: yolk sac
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619821
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: eye
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640521
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: limbs
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3568928
Stage: TS28
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3187321
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: placenta
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672821
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: lung
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684621
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: liver
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2611521
Stage: TS21
Assay Id: MGI:5688699
Age: embryonic day 13.5
Image: 9
Specimen Label: u. cord
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689422
Stage: TS22
Assay Id: MGI:5688700
Age: embryonic day 14.5
Image: 9
Specimen Label: brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610522
Stage: TS22
Assay Id: MGI:5688700
Age: embryonic day 14.5
Image: 9
Specimen Label: heart
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672822
Stage: TS22
Assay Id: MGI:5688700
Age: embryonic day 14.5
Image: 9
Specimen Label: lung
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:5688678
Assay Type: RT-PCR
Annotation Date: 2015-10-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684622
Stage: TS22
Assay Id: MGI:5688700
Age: embryonic day 14.5
Image: 9
Specimen Label: liver
Detected: true
Specimen Num: 5