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Search results 1 to 100 out of 309 for Muc2

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Type Details Score
Gene
Type: gene
Organism: human
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Gene
Type: gene
Organism: frog, western clawed
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Gene
Type: gene
Organism: dog, domestic
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Gene
Type: gene
Organism: rat
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Gene
Type: gene
Organism: chimpanzee
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Gene
Type: gene
Organism: cattle
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Gene
Type: gene
Organism: chicken
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Gene
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression  
Probe: MGI:5576882
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7463994
Age: postnatal adult
Image: S12E - Muc2
Specimen Label: S12E - Muc2
Detected: true
Specimen Num: 1
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GXD Expression      
Probe: MGI:4453820
Assay Type: RT-PCR
Annotation Date: 2010-06-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1880928
Stage: TS28
Assay Id: MGI:4453842
Age: postnatal adult
Specimen Label: Muc2
Detected: false
Specimen Num: 2
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GXD Expression      
Probe: MGI:4453820
Assay Type: RT-PCR
Annotation Date: 2010-06-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1880927
Stage: TS27
Assay Id: MGI:4453842
Age: postnatal newborn
Specimen Label: Muc2
Detected: false
Specimen Num: 8
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GXD Expression      
Probe: MGI:4453820
Assay Type: RT-PCR
Annotation Date: 2010-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276428
Stage: TS28
Assay Id: MGI:4453842
Age: postnatal
Specimen Label: Muc2
Detected: true
Specimen Num: 13
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Publication  
First Author: Wu M
Year: 2018
Journal: Int J Mol Sci
Title: The Dynamic Changes of Gut Microbiota in Muc2 Deficient Mice.
Volume: 19
Issue: 9
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Publication
First Author: Yu T
Year: 2016
Journal: Cell Death Dis
Title: KLF4 deletion alters gastric cell lineage and induces MUC2 expression.
Volume: 7
Issue: 6
Pages: e2255
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GXD Expression  
Probe: MGI:3799241
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3577828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7463976
Age: postnatal adult
Image: S12E - Muc2
Specimen Label: S12E - Muc2
Detected: true
Specimen Num: 7
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Publication
First Author: Cornick S
Year: 2019
Journal: Nat Commun
Title: VAMP8-mediated MUC2 mucin exocytosis from colonic goblet cells maintains innate intestinal homeostasis.
Volume: 10
Issue: 1
Pages: 4306
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Publication
First Author: Feofanova NA
Year: 2022
Journal: PLoS One
Title: L-fucose reduces gut inflammation due to T-regulatory response in Muc2 null mice.
Volume: 17
Issue: 12
Pages: e0278714
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Publication
First Author: Birchenough GM
Year: 2016
Journal: Science
Title: A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.
Volume: 352
Issue: 6293
Pages: 1535-42
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Publication
First Author: Johansson ME
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria.
Volume: 105
Issue: 39
Pages: 15064-9
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Publication
First Author: Tiwari S
Year: 2021
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Autophagy is required during high MUC2 mucin biosynthesis in colonic goblet cells to contend metabolic stress.
Volume: 321
Issue: 5
Pages: G489-G499
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Publication
First Author: Van der Sluis M
Year: 2006
Journal: Gastroenterology
Title: Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection.
Volume: 131
Issue: 1
Pages: 117-29
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Publication  
First Author: Verna G
Year: 2026
Journal: J Clin Invest
Title: A missense mutation in Muc2 promotes gut microbiome and metabolome-dependent colitis-associated tumorigenesis.
Volume: 136
Issue: 1
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Publication
First Author: Bergstrom KS
Year: 2010
Journal: PLoS Pathog
Title: Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa.
Volume: 6
Issue: 5
Pages: e1000902
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Publication
First Author: Kumar M
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice.
Volume: 312
Issue: 1
Pages: G34-G45
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Publication
First Author: Leon-Coria A
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury.
Volume: 11
Issue: 1
Pages: 77-98
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Publication
First Author: Yoon CK
Year: 2026
Journal: Cell Rep
Title: OmpW-mediated sensing of MUC2 GalNAc contributes to the ileal tropism of Salmonella Typhi.
Volume: 45
Issue: 8
Pages: 117801
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Publication
First Author: Zarepour M
Year: 2013
Journal: Infect Immun
Title: The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis.
Volume: 81
Issue: 10
Pages: 3672-83
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Publication
First Author: Liso M
Year: 2020
Journal: Inflamm Bowel Dis
Title: A Specific Mutation in Muc2 Determines Early Dysbiosis in Colitis-Prone Winnie Mice.
Volume: 26
Issue: 4
Pages: 546-556
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Publication
First Author: Stahl M
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion.
Volume: 315
Issue: 2
Pages: G195-G205
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Publication
First Author: Bao Y
Year: 2014
Journal: PLoS One
Title: MicroRNA profiling in Muc2 knockout mice of colitis-associated cancer model reveals epigenetic alterations during chronic colitis malignant transformation.
Volume: 9
Issue: 6
Pages: e99132
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Publication
First Author: Lu P
Year: 2013
Journal: PLoS One
Title: High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice.
Volume: 8
Issue: 6
Pages: e65878
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Publication
First Author: Mej?as-Luque R
Year: 2010
Journal: Oncogene
Title: Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors.
Volume: 29
Issue: 12
Pages: 1753-62
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Publication  
First Author: Gorman H
Year: 2023
Journal: Front Immunol
Title: IgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing.
Volume: 14
Pages: 1211336
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Publication
First Author: Tawiah A
Year: 2018
Journal: Am J Pathol
Title: High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells.
Volume: 188
Issue: 6
Pages: 1354-1373
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Publication      
First Author: Brandl K
Year: 2010
Journal: MGI Direct Data Submission
Title: Muskatenwein is an allele of Muc2 and confers susceptibility to DSS-induced colitis
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Publication
First Author: Yang K
Year: 2008
Journal: Cancer Res
Title: Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.
Volume: 68
Issue: 18
Pages: 7313-22
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Publication
First Author: Aslam F
Year: 2001
Journal: Cancer Res
Title: The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters.
Volume: 61
Issue: 2
Pages: 570-6
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Publication
First Author: Burger-van Paassen N
Year: 2012
Journal: PLoS One
Title: Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3?, Reg3? and angiogenin-4.
Volume: 7
Issue: 6
Pages: e38798
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Publication  
First Author: Saxena A
Year: 2024
Journal: Int J Mol Sci
Title: Aryl Hydrocarbon Receptor Regulates Muc2 Production Independently of IL-22 during Colitis.
Volume: 25
Issue: 4
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Publication
First Author: van der Sluis M
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.
Volume: 369
Issue: 4
Pages: 1108-13
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Publication
First Author: van der Sluis M
Year: 2004
Journal: Biochem Biophys Res Commun
Title: The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells.
Volume: 325
Issue: 3
Pages: 952-60
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Publication
First Author: Sch?tte A
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Microbial-induced meprin ? cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus.
Volume: 111
Issue: 34
Pages: 12396-401
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Publication
First Author: Tashiro M
Year: 2017
Journal: PLoS One
Title: The N-terminal region of serum amyloid A3 protein activates NF-?B and up-regulates MUC2 mucin mRNA expression in mouse colonic epithelial cells.
Volume: 12
Issue: 7
Pages: e0181796
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Publication
First Author: Johansson ME
Year: 2009
Journal: J Proteome Res
Title: Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein.
Volume: 8
Issue: 7
Pages: 3549-57
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Publication
First Author: Thomsson KA
Year: 2012
Journal: Glycobiology
Title: Detailed O-glycomics of the Muc2 mucin from colon of wild-type, core 1- and core 3-transferase-deficient mice highlights differences compared with human MUC2.
Volume: 22
Issue: 8
Pages: 1128-39
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Publication  
First Author: Fang F
Year: 2023
Journal: Int J Mol Sci
Title: Slowed Intestinal Transit Induced by Less Mucus in Intestinal Goblet Cell Piezo1-Deficient Mice through Impaired Epithelial Homeostasis.
Volume: 24
Issue: 18
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Publication
First Author: Tsai K
Year: 2020
Journal: J Immunol
Title: Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen.
Volume: 205
Issue: 2
Pages: 329-334
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Publication
First Author: Velcich A
Year: 2002
Journal: Science
Title: Colorectal cancer in mice genetically deficient in the mucin Muc2.
Volume: 295
Issue: 5560
Pages: 1726-9
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Publication
First Author: Bergstrom K
Year: 2020
Journal: Science
Title: Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota.
Volume: 370
Issue: 6515
Pages: 467-472
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Publication
First Author: Tsuru A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Negative feedback by IRE1? optimizes mucin production in goblet cells.
Volume: 110
Issue: 8
Pages: 2864-9
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Publication
First Author: An G
Year: 2007
Journal: J Exp Med
Title: Increased susceptibility to colitis and colorectal tumors in mice lacking core 3-derived O-glycans.
Volume: 204
Issue: 6
Pages: 1417-29
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Publication
First Author: Moutin EB
Year: 2024
Journal: Cell Mol Gastroenterol Hepatol
Title: Extracellular Matrix Orchestration of Tissue Remodeling in the Chronically Inflamed Mouse Colon.
Volume: 17
Issue: 4
Pages: 639-656
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Publication
First Author: Amat CB
Year: 2017
Journal: Am J Pathol
Title: Cysteine Protease-Dependent Mucous Disruptions and Differential Mucin Gene Expression in Giardia duodenalis Infection.
Volume: 187
Issue: 11
Pages: 2486-2498
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Publication
First Author: Morozova MV
Year: 2022
Journal: Sci Rep
Title: Colitis-associated intestinal microbiota regulates brain glycine and host behavior in mice.
Volume: 12
Issue: 1
Pages: 16345
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Publication
First Author: Borisova MA
Year: 2020
Journal: Sci Rep
Title: Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epithelium.
Volume: 10
Issue: 1
Pages: 21135
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Publication
First Author: Das I
Year: 2013
Journal: J Exp Med
Title: Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins.
Volume: 210
Issue: 6
Pages: 1201-16
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Publication  
First Author: Ephraim R
Year: 2023
Journal: Cancers (Basel)
Title: Differential Gene Expression of Checkpoint Markers and Cancer Markers in Mouse Models of Spontaneous Chronic Colitis.
Volume: 15
Issue: 19
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Publication
First Author: Han C
Year: 2022
Journal: Am J Pathol
Title: Activation of 5-Hydroxytryptamine 4 Receptor Improves Colonic Barrier Function by Triggering Mucin 2 Production in a Mouse Model of Type 1 Diabetes.
Volume: 192
Issue: 6
Pages: 876-886
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Publication
First Author: Birchenough GMH
Year: 2023
Journal: Cell Rep
Title: Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection.
Volume: 42
Issue: 2
Pages: 112084
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Publication
First Author: van Klinken BJ
Year: 1999
Journal: Am J Physiol
Title: Gastrointestinal expression and partial cDNA cloning of murine Muc2.
Volume: 276
Issue: 1
Pages: G115-24
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Publication
First Author: Kober OI
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: ?? T-cell-deficient mice show alterations in mucin expression, glycosylation, and goblet cells but maintain an intact mucus layer.
Volume: 306
Issue: 7
Pages: G582-93
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Publication
First Author: Ehrencrona E
Year: 2021
Journal: J Biol Chem
Title: The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds.
Volume: 297
Issue: 1
Pages: 100871
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Publication
First Author: Schneider H
Year: 2018
Journal: Sci Rep
Title: Study of mucin turnover in the small intestine by in vivo labeling.
Volume: 8
Issue: 1
Pages: 5760
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Publication
First Author: Heazlewood CK
Year: 2008
Journal: PLoS Med
Title: Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis.
Volume: 5
Issue: 3
Pages: e54
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Publication
First Author: van der Sluis M
Year: 2008
Journal: Lab Invest
Title: Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice.
Volume: 88
Issue: 6
Pages: 634-42
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Publication
First Author: Nishida K
Year: 2009
Journal: FASEB J
Title: Interleukin-18 is a crucial determinant of vulnerability of the mouse rectum to psychosocial stress.
Volume: 23
Issue: 6
Pages: 1797-805
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Publication
First Author: Rogier EW
Year: 2014
Journal: Pathogens
Title: Secretory IgA is Concentrated in the Outer Layer of Colonic Mucus along with Gut Bacteria.
Volume: 3
Issue: 2
Pages: 390-403
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Publication
First Author: Shan M
Year: 2013
Journal: Science
Title: Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals.
Volume: 342
Issue: 6157
Pages: 447-53
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Publication
First Author: Escande F
Year: 2004
Journal: Biochim Biophys Acta
Title: The mouse secreted gel-forming mucin gene cluster.
Volume: 1676
Issue: 3
Pages: 240-50
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Publication
First Author: Khatri IA
Year: 2001
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis.
Volume: 280
Issue: 6
Pages: G1321-30
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Publication
First Author: Yamaguchi K
Year: 2008
Journal: Mol Cancer Ther
Title: Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in ApcMin/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways.
Volume: 7
Issue: 9
Pages: 2779-87
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Publication
First Author: Wallace JL
Year: 2011
Journal: Am J Pathol
Title: Muc-2-deficient mice display a sex-specific, COX-2-related impairment of gastric mucosal repair.
Volume: 178
Issue: 3
Pages: 1126-33
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Publication  
First Author: Znalesniak EB
Year: 2017
Journal: Int J Mol Sci
Title: Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.
Volume: 18
Issue: 6
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Publication  
First Author: Gonzalez-Perez V
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice.
Volume: 118
Issue: 3
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Publication
First Author: Bel S
Year: 2012
Journal: J Biol Chem
Title: Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis.
Volume: 287
Issue: 30
Pages: 25631-9
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Publication
First Author: Taniguchi M
Year: 2023
Journal: Mucosal Immunol
Title: Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon.
Volume: 16
Issue: 5
Pages: 624-641
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Publication
First Author: Kaden-Volynets V
Year: 2019
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Deletion of the Casp8 gene in mice results in ileocolitis, gut barrier dysfunction, and malassimilation, which can be partially attenuated by inulin or sodium butyrate.
Volume: 317
Issue: 4
Pages: G493-G507
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Publication
First Author: Xu H
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 knockout mice.
Volume: 303
Issue: 3
Pages: G335-43
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Publication
First Author: Yang W
Year: 2005
Journal: Am J Pathol
Title: Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice.
Volume: 166
Issue: 4
Pages: 1239-46
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Publication
First Author: Yang W
Year: 2003
Journal: Cancer Res
Title: Targeted inactivation of p27kip1 is sufficient for large and small intestinal tumorigenesis in the mouse, which can be augmented by a Western-style high-risk diet.
Volume: 63
Issue: 16
Pages: 4990-6
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Publication
First Author: Nam KT
Year: 2009
Journal: Gastroenterology
Title: Amphiregulin-deficient mice develop spasmolytic polypeptide expressing metaplasia and intestinal metaplasia.
Volume: 136
Issue: 4
Pages: 1288-96
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Publication
First Author: Wang R
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Type 2 cGMP-dependent protein kinase regulates proliferation and differentiation in the colonic mucosa.
Volume: 303
Issue: 2
Pages: G209-19
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Publication
First Author: Bergstrom KS
Year: 2008
Journal: Infect Immun
Title: Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen.
Volume: 76
Issue: 2
Pages: 796-811
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Publication  
First Author: Liu W
Year: 2020
Journal: Biosci Rep
Title: Dynamic characterization of intestinal metaplasia in the gastric corpus mucosa of Atp4a-deficient mice.
Volume: 40
Issue: 2
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Publication
First Author: Waddell A
Year: 2019
Journal: J Immunol
Title: IL-33 Induces Murine Intestinal Goblet Cell Differentiation Indirectly via Innate Lymphoid Cell IL-13 Secretion.
Volume: 202
Issue: 2
Pages: 598-607
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Publication
First Author: Burger-van Paassen N
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Colitis development during the suckling-weaning transition in mucin Muc2-deficient mice.
Volume: 301
Issue: 4
Pages: G667-78
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Publication
First Author: Bomidi C
Year: 2025
Journal: J Virol
Title: Loss of mucin 2 and MHC II molecules causes rare resistance to murine RV infection.
Volume: 99
Issue: 2
Pages: e0150724
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Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
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