Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
311
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Mucin-2 (MUC2) belongs to the mucin family. They are high molecular weight proteins that are components of mucus and are synthesised and secreted by specialised cells of the epithelium (goblet cells, cells of mucous glands) or non mucin-secreting cells []. There are two main mucin subfamilies: secreted mucins or gel-forming mucins (MUC2, MUC5AC, MUC5B, MUC6) and membrane-bound mucins (MUC1, MUC3, MUC4, MUC12, MUC17) []. In colon epithelium, MUC2 forms a net-like disulfide-bonded polymer structure that organise the two mucus layer of colon []. The colon inner layer is adherent to intestinal epithelial cells (IECs) and does not allow bacteria to penetrate, while the outer layer is inhabited by the microbiota []. In the small intestine, MUC2 modulates inflammatory responses and delivers tolerogenic signal to antigen-sampling dendritic cells (DCs) []. It plays an important role in gut homeostasis and promotes oral tolerance []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansson ME |
Year: |
2009 |
Journal: |
J Proteome Res |
Title: |
Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the Muc2 mucin, is strongly bound to the Fcgbp protein. |
Volume: |
8 |
Issue: |
7 |
Pages: |
3549-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shan M |
Year: |
2013 |
Journal: |
Science |
Title: |
Mucus enhances gut homeostasis and oral tolerance by delivering immunoregulatory signals. |
Volume: |
342 |
Issue: |
6157 |
Pages: |
447-53 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5576882 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7463994 |
Age: |
postnatal adult |
Image: |
S12E - Muc2 |
|
Specimen Label: |
S12E - Muc2 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4453820 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-06-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1880927 |
|
Stage: |
TS27 |
Assay Id: |
MGI:4453842 |
Age: |
postnatal newborn |
|
|
Specimen Label: |
Muc2 |
Detected: |
false |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4453820 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-06-01 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1880928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4453842 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Muc2 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4453820 |
Assay Type: |
RT-PCR |
Annotation Date: |
2010-06-01 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:4453842 |
Age: |
postnatal |
|
|
Specimen Label: |
Muc2 |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
132
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Borchers MT |
Year: |
1999 |
Journal: |
Am J Physiol |
Title: |
Regulation of human airway mucins by acrolein and inflammatory mediators. |
Volume: |
276 |
Issue: |
4 Pt 1 |
Pages: |
L549-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu T |
Year: |
2016 |
Journal: |
Cell Death Dis |
Title: |
KLF4 deletion alters gastric cell lineage and induces MUC2 expression. |
Volume: |
7 |
Issue: |
6 |
Pages: |
e2255 |
|
•
•
•
•
•
|
Publication |
First Author: |
Feofanova NA |
Year: |
2022 |
Journal: |
PLoS One |
Title: |
L-fucose reduces gut inflammation due to T-regulatory response in Muc2 null mice. |
Volume: |
17 |
Issue: |
12 |
Pages: |
e0278714 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birchenough GM |
Year: |
2016 |
Journal: |
Science |
Title: |
A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion. |
Volume: |
352 |
Issue: |
6293 |
Pages: |
1535-42 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:3799241 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-04-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3577828 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:7463976 |
Age: |
postnatal adult |
Image: |
S12E - Muc2 |
|
Specimen Label: |
S12E - Muc2 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Johansson ME |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. |
Volume: |
105 |
Issue: |
39 |
Pages: |
15064-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Van der Sluis M |
Year: |
2006 |
Journal: |
Gastroenterology |
Title: |
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection. |
Volume: |
131 |
Issue: |
1 |
Pages: |
117-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar M |
Year: |
2017 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Probiotic mixture VSL#3 reduces colonic inflammation and improves intestinal barrier function in Muc2 mucin-deficient mice. |
Volume: |
312 |
Issue: |
1 |
Pages: |
G34-G45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leon-Coria A |
Year: |
2021 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Muc2 Mucin and Nonmucin Microbiota Confer Distinct Innate Host Defense in Disease Susceptibility and Colonic Injury. |
Volume: |
11 |
Issue: |
1 |
Pages: |
77-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bergstrom KS |
Year: |
2010 |
Journal: |
PLoS Pathog |
Title: |
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. |
Volume: |
6 |
Issue: |
5 |
Pages: |
e1000902 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zarepour M |
Year: |
2013 |
Journal: |
Infect Immun |
Title: |
The mucin Muc2 limits pathogen burdens and epithelial barrier dysfunction during Salmonella enterica serovar Typhimurium colitis. |
Volume: |
81 |
Issue: |
10 |
Pages: |
3672-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liso M |
Year: |
2020 |
Journal: |
Inflamm Bowel Dis |
Title: |
A Specific Mutation in Muc2 Determines Early Dysbiosis in Colitis-Prone Winnie Mice. |
Volume: |
26 |
Issue: |
4 |
Pages: |
546-556 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stahl M |
Year: |
2018 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
The Muc2 mucin coats murine Paneth cell granules and facilitates their content release and dispersion. |
Volume: |
315 |
Issue: |
2 |
Pages: |
G195-G205 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bao Y |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
MicroRNA profiling in Muc2 knockout mice of colitis-associated cancer model reveals epigenetic alterations during chronic colitis malignant transformation. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e99132 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu P |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
High beta-palmitate fat controls the intestinal inflammatory response and limits intestinal damage in mucin Muc2 deficient mice. |
Volume: |
8 |
Issue: |
6 |
Pages: |
e65878 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gorman H |
Year: |
2023 |
Journal: |
Front Immunol |
Title: |
IgGFc-binding protein and MUC2 mucin produced by colonic goblet-like cells spatially interact non-covalently and regulate wound healing. |
Volume: |
14 |
|
Pages: |
1211336 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aslam F |
Year: |
2001 |
Journal: |
Cancer Res |
Title: |
The Sp family of transcription factors in the regulation of the human and mouse MUC2 gene promoters. |
Volume: |
61 |
Issue: |
2 |
Pages: |
570-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Porchet N |
Year: |
2004 |
Journal: |
Med Sci (Paris) |
Title: |
[MUC genes: mucin or not mucin? That is the question]. |
Volume: |
20 |
Issue: |
5 |
Pages: |
569-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tawiah A |
Year: |
2018 |
Journal: |
Am J Pathol |
Title: |
High MUC2 Mucin Expression and Misfolding Induce Cellular Stress, Reactive Oxygen Production, and Apoptosis in Goblet Cells. |
Volume: |
188 |
Issue: |
6 |
Pages: |
1354-1373 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brandl K |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Muskatenwein is an allele of Muc2 and confers susceptibility to DSS-induced colitis |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yang K |
Year: |
2008 |
Journal: |
Cancer Res |
Title: |
Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation. |
Volume: |
68 |
Issue: |
18 |
Pages: |
7313-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burger-van Paassen N |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Mucin Muc2 deficiency and weaning influences the expression of the innate defense genes Reg3β, Reg3γ and angiogenin-4. |
Volume: |
7 |
Issue: |
6 |
Pages: |
e38798 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
2680
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
4576
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Sluis M |
Year: |
2008 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells. |
Volume: |
369 |
Issue: |
4 |
Pages: |
1108-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Sluis M |
Year: |
2004 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells. |
Volume: |
325 |
Issue: |
3 |
Pages: |
952-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schütte A |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus. |
Volume: |
111 |
Issue: |
34 |
Pages: |
12396-401 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tashiro M |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
The N-terminal region of serum amyloid A3 protein activates NF-κB and up-regulates MUC2 mucin mRNA expression in mouse colonic epithelial cells. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e0181796 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu M |
Year: |
2018 |
Journal: |
Int J Mol Sci |
Title: |
The Dynamic Changes of Gut Microbiota in Muc2 Deficient Mice. |
Volume: |
19 |
Issue: |
9 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Tsai K |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
Cutting Edge: Intestinal Mucus Limits the Clonal Deletion of Developing T Cells Specific for an Oral Antigen. |
Volume: |
205 |
Issue: |
2 |
Pages: |
329-334 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velcich A |
Year: |
2002 |
Journal: |
Science |
Title: |
Colorectal cancer in mice genetically deficient in the mucin Muc2. |
Volume: |
295 |
Issue: |
5560 |
Pages: |
1726-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tsuru A |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Negative feedback by IRE1β optimizes mucin production in goblet cells. |
Volume: |
110 |
Issue: |
8 |
Pages: |
2864-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bergstrom K |
Year: |
2020 |
Journal: |
Science |
Title: |
Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota. |
Volume: |
370 |
Issue: |
6515 |
Pages: |
467-472 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moutin EB |
Year: |
2024 |
Journal: |
Cell Mol Gastroenterol Hepatol |
Title: |
Extracellular Matrix Orchestration of Tissue Remodeling in the Chronically Inflamed Mouse Colon. |
Volume: |
17 |
Issue: |
4 |
Pages: |
639-656 |
|
•
•
•
•
•
|
Publication |
First Author: |
Borisova MA |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Mucin-2 knockout is a model of intercellular junction defects, mitochondrial damage and ATP depletion in the intestinal epithelium. |
Volume: |
10 |
Issue: |
1 |
Pages: |
21135 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morozova MV |
Year: |
2022 |
Journal: |
Sci Rep |
Title: |
Colitis-associated intestinal microbiota regulates brain glycine and host behavior in mice. |
Volume: |
12 |
Issue: |
1 |
Pages: |
16345 |
|
•
•
•
•
•
|
Publication |
First Author: |
Amat CB |
Year: |
2017 |
Journal: |
Am J Pathol |
Title: |
Cysteine Protease-Dependent Mucous Disruptions and Differential Mucin Gene Expression in Giardia duodenalis Infection. |
Volume: |
187 |
Issue: |
11 |
Pages: |
2486-2498 |
|
•
•
•
•
•
|
Publication |
First Author: |
Das I |
Year: |
2013 |
Journal: |
J Exp Med |
Title: |
Glucocorticoids alleviate intestinal ER stress by enhancing protein folding and degradation of misfolded proteins. |
Volume: |
210 |
Issue: |
6 |
Pages: |
1201-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ephraim R |
Year: |
2023 |
Journal: |
Cancers (Basel) |
Title: |
Differential Gene Expression of Checkpoint Markers and Cancer Markers in Mouse Models of Spontaneous Chronic Colitis. |
Volume: |
15 |
Issue: |
19 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Han C |
Year: |
2022 |
Journal: |
Am J Pathol |
Title: |
Activation of 5-Hydroxytryptamine 4 Receptor Improves Colonic Barrier Function by Triggering Mucin 2 Production in a Mouse Model of Type 1 Diabetes. |
Volume: |
192 |
Issue: |
6 |
Pages: |
876-886 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birchenough GMH |
Year: |
2023 |
Journal: |
Cell Rep |
Title: |
Muc2-dependent microbial colonization of the jejunal mucus layer is diet sensitive and confers local resistance to enteric pathogen infection. |
Volume: |
42 |
Issue: |
2 |
Pages: |
112084 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Klinken BJ |
Year: |
1999 |
Journal: |
Am J Physiol |
Title: |
Gastrointestinal expression and partial cDNA cloning of murine Muc2. |
Volume: |
276 |
Issue: |
1 Pt 1 |
Pages: |
G115-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burger-van Paassen N |
Year: |
2011 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Colitis development during the suckling-weaning transition in mucin Muc2-deficient mice. |
Volume: |
301 |
Issue: |
4 |
Pages: |
G667-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ehrencrona E |
Year: |
2021 |
Journal: |
J Biol Chem |
Title: |
The IgGFc-binding protein FCGBP is secreted with all GDPH sequences cleaved but maintained by interfragment disulfide bonds. |
Volume: |
297 |
Issue: |
1 |
Pages: |
100871 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schneider H |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Study of mucin turnover in the small intestine by in vivo labeling. |
Volume: |
8 |
Issue: |
1 |
Pages: |
5760 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heazlewood CK |
Year: |
2008 |
Journal: |
PLoS Med |
Title: |
Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. |
Volume: |
5 |
Issue: |
3 |
Pages: |
e54 |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Sluis M |
Year: |
2008 |
Journal: |
Lab Invest |
Title: |
Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice. |
Volume: |
88 |
Issue: |
6 |
Pages: |
634-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang W |
Year: |
2005 |
Journal: |
Am J Pathol |
Title: |
Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice. |
Volume: |
166 |
Issue: |
4 |
Pages: |
1239-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Znalesniak EB |
Year: |
2017 |
Journal: |
Int J Mol Sci |
Title: |
Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes. |
Volume: |
18 |
Issue: |
6 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wallace JL |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Muc-2-deficient mice display a sex-specific, COX-2-related impairment of gastric mucosal repair. |
Volume: |
178 |
Issue: |
3 |
Pages: |
1126-33 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rogier EW |
Year: |
2014 |
Journal: |
Pathogens |
Title: |
Secretory IgA is Concentrated in the Outer Layer of Colonic Mucus along with Gut Bacteria. |
Volume: |
3 |
Issue: |
2 |
Pages: |
390-403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Escande F |
Year: |
2004 |
Journal: |
Biochim Biophys Acta |
Title: |
The mouse secreted gel-forming mucin gene cluster. |
Volume: |
1676 |
Issue: |
3 |
Pages: |
240-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khatri IA |
Year: |
2001 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Characteristics of rodent intestinal mucin Muc3 and alterations in a mouse model of human cystic fibrosis. |
Volume: |
280 |
Issue: |
6 |
Pages: |
G1321-30 |
|
•
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Publication |
First Author: |
Gonzalez-Perez V |
Year: |
2021 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice. |
Volume: |
118 |
Issue: |
3 |
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•
•
•
•
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Publication |
First Author: |
Taniguchi M |
Year: |
2023 |
Journal: |
Mucosal Immunol |
Title: |
Sialylation shapes mucus architecture inhibiting bacterial invasion in the colon. |
Volume: |
16 |
Issue: |
5 |
Pages: |
624-641 |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
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•
•
•
•
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Publication |
First Author: |
Ye J |
Year: |
2021 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Deletion of mucin 2 induces colitis with concomitant metabolic abnormalities in mice. |
Volume: |
320 |
Issue: |
5 |
Pages: |
G791-G803 |
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•
•
•
•
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Publication |
First Author: |
Kissoon-Singh V |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Entamoeba histolytica exacerbates epithelial tight junction permeability and proinflammatory responses in Muc2(-/-) mice. |
Volume: |
182 |
Issue: |
3 |
Pages: |
852-65 |
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•
•
•
•
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Publication |
First Author: |
Hecht AL |
Year: |
2017 |
Journal: |
Cell Host Microbe |
Title: |
A Two-Component System Regulates Bacteroides fragilis Toxin to Maintain Intestinal Homeostasis and Prevent Lethal Disease. |
Volume: |
22 |
Issue: |
4 |
Pages: |
443-448.e5 |
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•
•
•
•
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Publication |
First Author: |
Bao Y |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Tumor suppressor microRNA-27a in colorectal carcinogenesis and progression by targeting SGPP1 and Smad2. |
Volume: |
9 |
Issue: |
8 |
Pages: |
e105991 |
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•
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•
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Publication |
First Author: |
Hamano S |
Year: |
2008 |
Journal: |
Genes Immun |
Title: |
Gender and genetic control of resistance to intestinal amebiasis in inbred mice. |
Volume: |
9 |
Issue: |
5 |
Pages: |
452-61 |
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•
•
•
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Publication |
First Author: |
Wenzel UA |
Year: |
2015 |
Journal: |
PLoS One |
Title: |
CD103+ CD11b+ Dendritic Cells Induce Th17 T Cells in Muc2-Deficient Mice with Extensively Spread Colitis. |
Volume: |
10 |
Issue: |
6 |
Pages: |
e0130750 |
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•
•
•
•
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Publication |
First Author: |
Wenzel UA |
Year: |
2014 |
Journal: |
PLoS One |
Title: |
Spontaneous colitis in Muc2-deficient mice reflects clinical and cellular features of active ulcerative colitis. |
Volume: |
9 |
Issue: |
6 |
Pages: |
e100217 |
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•
•
•
•
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Publication |
First Author: |
Wenzel TJ |
Year: |
2022 |
Journal: |
Biochim Biophys Acta Mol Basis Dis |
Title: |
Dietary fats modulate neuroinflammation in mucin 2 knock out mice model of spontaneous colitis. |
Volume: |
1868 |
Issue: |
3 |
Pages: |
166336 |
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•
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Publication |
First Author: |
Brandl K |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Record for "Schlendrian", updated July 1st, 2009 |
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Publication |
First Author: |
Devereaux J |
Year: |
2024 |
Journal: |
Front Med (Lausanne) |
Title: |
Alterations in tryptophan metabolism and de novo NAD(+) biosynthesis within the microbiota-gut-brain axis in chronic intestinal inflammation. |
Volume: |
11 |
|
Pages: |
1379335 |
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•
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Publication |
First Author: |
Robinson AM |
Year: |
2017 |
Journal: |
Am J Physiol Gastrointest Liver Physiol |
Title: |
Alterations of colonic function in the Winnie mouse model of spontaneous chronic colitis. |
Volume: |
312 |
Issue: |
1 |
Pages: |
G85-G102 |
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•
•
•
•
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Publication |
First Author: |
McAlpine W |
Year: |
2018 |
Journal: |
MGI Direct Data Submission |
Title: |
Mutagenetix entry for nomoco |
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•
|
GXD Expression |
Probe: |
MGI:4357895 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-09-18 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702125 |
|
Stage: |
TS25 |
Assay Id: |
MGI:4358225 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
St |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4357895 |
Assay Type: |
RT-PCR |
Annotation Date: |
2009-09-18 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3287425 |
|
Stage: |
TS25 |
Assay Id: |
MGI:4358225 |
Age: |
embryonic day 17.5 |
|
|
Specimen Label: |
Int |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6368572 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-10-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1893926 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6368577 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
2 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6368572 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-10-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1893926 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6368577 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
3 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6368572 |
Assay Type: |
RT-PCR |
Annotation Date: |
2019-10-30 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1893926 |
|
Stage: |
TS26 |
Assay Id: |
MGI:6368577 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
4 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|