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Search results 1 to 100 out of 304 for Muc5ac

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0.036s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:7462440
Assay Type: Immunohistochemistry
Annotation Date: 2023-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1762528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7463978
Age: postnatal adult
Image: 1H - Muc5ac
Note: Expression is seen in pit cells.
Specimen Label: 1H - Muc5ac
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269528
Pattern: Single cells
Stage: TS28
Assay Id: MGI:6863934
Age: postnatal adult
Image: S3E - Muc5ac
Note: Expression is seen in goblet cells of the mainstem bronchi.
Specimen Label: S3E - Muc5ac
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269528
Pattern: Single cells
Stage: TS28
Assay Id: MGI:6863934
Age: postnatal adult
Image: S3F - Muc5ac
Note: Expression is seen in goblet cells of the mainstem bronchi.
Specimen Label: S3F - Muc5ac
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4453821
Assay Type: RT-PCR
Annotation Date: 2010-06-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1880928
Stage: TS28
Assay Id: MGI:4453844
Age: postnatal adult
Specimen Label: Muc5ac
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:4453821
Assay Type: RT-PCR
Annotation Date: 2010-06-01
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1880927
Stage: TS27
Assay Id: MGI:4453844
Age: postnatal newborn
Specimen Label: Muc5ac
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:4453821
Assay Type: RT-PCR
Annotation Date: 2010-06-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702128
Stage: TS28
Assay Id: MGI:4453844
Age: postnatal
Specimen Label: Muc5ac
Detected: true
Specimen Num: 14
Publication  
First Author: Bauer AK
Year: 2018
Journal: JCI Insight
Title: Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
Volume: 3
Issue: 15
Publication
First Author: Ehre C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs.
Volume: 109
Issue: 41
Pages: 16528-33
Publication  
First Author: Evans CM
Year: 2015
Journal: Nat Commun
Title: The polymeric mucin Muc5ac is required for allergic airway hyperreactivity.
Volume: 6
Pages: 6281
Publication
First Author: Marko CK
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: The ocular surface phenotype of Muc5ac and Muc5b null mice.
Volume: 55
Issue: 1
Pages: 291-300
Protein
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: true
Publication  
First Author: Magalhães A
Year: 2016
Journal: Sci Rep
Title: Muc5ac gastric mucin glycosylation is shaped by FUT2 activity and functionally impacts Helicobacter pylori binding.
Volume: 6
Pages: 25575
Publication
First Author: Song KS
Year: 2009
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Suppression of prostaglandin E2-induced MUC5AC overproduction by RGS4 in the airway.
Volume: 296
Issue: 4
Pages: L684-92
Publication
First Author: Tomasetto C
Year: 2000
Journal: Gastroenterology
Title: pS2/TFF1 interacts directly with the VWFC cysteine-rich domains of mucins.
Volume: 118
Issue: 1
Pages: 70-80
Publication
First Author: Yan F
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Interleukin-13-induced MUC5AC expression is regulated by a PI3K-NFAT3 pathway in mouse tracheal epithelial cells.
Volume: 446
Issue: 1
Pages: 49-53
Publication
First Author: Lakshmanan I
Year: 2016
Journal: Oncogene
Title: MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.
Volume: 35
Issue: 31
Pages: 4112-21
Publication
First Author: Muthupalani S
Year: 2019
Journal: Lab Invest
Title: Muc5ac null mice are predisposed to spontaneous gastric antro-pyloric hyperplasia and adenomas coupled with attenuated H. pylori-induced corpus mucous metaplasia.
Volume: 99
Issue: 12
Pages: 1887-1905
Publication
First Author: Livraghi-Butrico A
Year: 2017
Journal: Mucosal Immunol
Title: Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.
Volume: 10
Issue: 2
Pages: 395-407
Publication
First Author: Inatomi T
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Cloning of rat Muc5AC mucin gene: comparison of its structure and tissue distribution to that of human and mouse homologues.
Volume: 236
Issue: 3
Pages: 789-97
Publication
First Author: Jonckheere N
Year: 2004
Journal: Biochem J
Title: Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-beta/Smad4 signalling pathway is potentiated by Sp1.
Volume: 377
Issue: Pt 3
Pages: 797-808
Publication
First Author: Amini SE
Year: 2019
Journal: Histochem Cell Biol
Title: Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.
Volume: 152
Issue: 2
Pages: 167-174
GXD Expression  
Probe: MGI:5619501
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-04-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1762528
Stage: TS28
Assay Id: MGI:7461884
Age: postnatal adult
Image: 1H - Muc5ac
Note: There is no expression in pit cells
Specimen Label: 1H - Muc5ac
Detected: false
Specimen Num: 6
GXD Expression
Probe: MGI:6858139
Assay Type: Immunohistochemistry
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6863898
Age: postnatal adult
Image: S3F - Muc5ac
Note: Expressing cells are seen in the mainstem bronchi; they are not goblet cells.
Specimen Label: S3F - Muc5ac
Detected: true
Specimen Num: 16
GXD Expression
Probe: MGI:5302577
Assay Type: In situ reporter (knock in)
Annotation Date: 2022-02-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3269528
Pattern: Single cells
Stage: TS28
Assay Id: MGI:6863897
Age: postnatal adult
Image: S3E - Muc5ac
Note: Expressing cells in the mainstem bronchi are rare; they are not goblet cells.
Specimen Label: S3E - Muc5ac
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:5619501
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-04-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2718128
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:7461884
Age: postnatal adult
Image: 1H - Muc5ac
Specimen Label: 1H - Muc5ac
Detected: true
Specimen Num: 6
Publication
First Author: Jonckheere N
Year: 2012
Journal: Biochim Biophys Acta
Title: GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells.
Volume: 1819
Issue: 8
Pages: 869-76
Publication
First Author: Fakih D
Year: 2020
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.
Volume: 318
Issue: 6
Pages: L1270-L1279
Protein
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: true
Publication  
First Author: Singanayagam A
Year: 2022
Journal: J Clin Invest
Title: Airway mucins promote immunopathology in virus-exacerbated chronic obstructive pulmonary disease.
Volume: 132
Issue: 8
Publication
First Author: Cho HY
Year: 2021
Journal: Toxicol Pathol
Title: Role for Mucin-5AC in Upper and Lower Airway Pathogenesis in Mice.
Volume: 49
Issue: 5
Pages: 1077-1099
Publication
First Author: Chen Y
Year: 2001
Journal: Am J Respir Crit Care Med
Title: In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.
Volume: 164
Issue: 6
Pages: 1059-66
Publication
First Author: Floyd AM
Year: 2012
Journal: PLoS One
Title: Mucin deficiency causes functional and structural changes of the ocular surface.
Volume: 7
Issue: 12
Pages: e50704
Publication
First Author: Lukacs NW
Year: 2006
Journal: Am J Pathol
Title: Differential immune responses and pulmonary pathophysiology are induced by two different strains of respiratory syncytial virus.
Volume: 169
Issue: 3
Pages: 977-86
Publication  
First Author: Wang IJ
Year: 2009
Journal: Mol Vis
Title: Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.
Volume: 15
Pages: 108-19
Publication
First Author: Lakshmi SP
Year: 2018
Journal: J Immunol
Title: Airway Epithelial Cell Peroxisome Proliferator-Activated Receptor γ Regulates Inflammation and Mucin Expression in Allergic Airway Disease.
Volume: 201
Issue: 6
Pages: 1775-1783
Publication
First Author: Lewis BW
Year: 2020
Journal: J Immunol
Title: Ablation of IL-33 Suppresses Th2 Responses but Is Accompanied by Sustained Mucus Obstruction in the Scnn1b Transgenic Mouse Model.
Volume: 204
Issue: 6
Pages: 1650-1660
Publication
First Author: Ganguly K
Year: 2021
Journal: Cancer Res
Title: Secretory Mucin 5AC Promotes Neoplastic Progression by Augmenting KLF4-Mediated Pancreatic Cancer Cell Stemness.
Volume: 81
Issue: 1
Pages: 91-102
Publication
First Author: Almolki A
Year: 2008
Journal: Am J Pathol
Title: Heme oxygenase-1 prevents airway mucus hypersecretion induced by cigarette smoke in rodents and humans.
Volume: 173
Issue: 4
Pages: 981-92
Publication
First Author: Roy MG
Year: 2014
Journal: Nature
Title: Muc5b is required for airway defence.
Volume: 505
Issue: 7483
Pages: 412-6
Publication
First Author: Escande F
Year: 2004
Journal: Biochim Biophys Acta
Title: The mouse secreted gel-forming mucin gene cluster.
Volume: 1676
Issue: 3
Pages: 240-50
Publication
First Author: Dif F
Year: 2010
Journal: Eur Respir J
Title: Critical role of cytosolic phospholipase A2{alpha} in bronchial mucus hypersecretion in CFTR-deficient mice.
Volume: 36
Issue: 5
Pages: 1120-30
Publication
First Author: Hasnain SZ
Year: 2011
Journal: J Exp Med
Title: Muc5ac: a critical component mediating the rejection of enteric nematodes.
Volume: 208
Issue: 5
Pages: 893-900
Publication
First Author: Zhu Y
Year: 2008
Journal: J Physiol
Title: Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.
Volume: 586
Issue: 7
Pages: 1977-92
Publication
First Author: Sweeter JM
Year: 2021
Journal: Sci Rep
Title: Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.
Volume: 11
Issue: 1
Pages: 13037
Publication
First Author: Ganguly K
Year: 2022
Journal: Gastroenterology
Title: Mucin 5AC Serves as the Nexus for β-Catenin/c-Myc Interplay to Promote Glutamine Dependency During Pancreatic Cancer Chemoresistance.
Volume: 162
Issue: 1
Pages: 253-268.e13
Publication
First Author: Jang MK
Year: 2010
Journal: Biochem Biophys Res Commun
Title: The tyrosine phosphatase, SHP-1, is involved in bronchial mucin production during oxidative stress.
Volume: 393
Issue: 1
Pages: 137-43
Publication
First Author: Sanders PN
Year: 2013
Journal: Sci Transl Med
Title: CaMKII is essential for the proasthmatic effects of oxidation.
Volume: 5
Issue: 195
Pages: 195ra97
Publication
First Author: Verzi MP
Year: 2008
Journal: Gastroenterology
Title: Transcription factor foxq1 controls mucin gene expression and granule content in mouse stomach surface mucous cells.
Volume: 135
Issue: 2
Pages: 591-600
Publication  
First Author: Shekels LL
Year: 1995
Journal: Biochem J
Title: Mouse gastric mucin: cloning and chromosomal localization.
Volume: 311 ( Pt 3)
Pages: 775-85
Publication
First Author: Tsao PN
Year: 2011
Journal: Development
Title: Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.
Volume: 138
Issue: 16
Pages: 3533-43
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Morgan LE
Year: 2021
Journal: Nat Commun
Title: Disulfide disruption reverses mucus dysfunction in allergic airway disease.
Volume: 12
Issue: 1
Pages: 249
GXD Expression    
Probe: MGI:6511961
Assay Type: RT-PCR
Annotation Date: 2021-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:6512010
Age: embryonic day 16.5
Image: 5
Specimen Label: E16.5
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6511961
Assay Type: RT-PCR
Annotation Date: 2021-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672824
Stage: TS24
Assay Id: MGI:6512010
Age: embryonic day 16.5
Image: 5
Specimen Label: E16.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6511961
Assay Type: RT-PCR
Annotation Date: 2021-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:6512010
Age: embryonic day 17.5
Image: 5
Specimen Label: E17.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6511961
Assay Type: RT-PCR
Annotation Date: 2021-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672825
Stage: TS25
Assay Id: MGI:6512010
Age: embryonic day 17.5
Image: 5
Specimen Label: E17.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6511961
Assay Type: RT-PCR
Annotation Date: 2021-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6512010
Age: postnatal adult
Image: 5
Specimen Label: Adult
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6511961
Assay Type: RT-PCR
Annotation Date: 2021-03-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6512010
Age: postnatal adult
Image: 5
Specimen Label: Adult
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6858100
Assay Type: RT-PCR
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6860375
Age: postnatal month 6
Image: S8
Specimen Label: Wild-type
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6858100
Assay Type: RT-PCR
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6860375
Age: postnatal month 6
Image: S8
Specimen Label: NANCI
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6858100
Assay Type: RT-PCR
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6860375
Age: postnatal month 6
Image: S8
Specimen Label: Nkx2.1
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6858100
Assay Type: RT-PCR
Annotation Date: 2022-01-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:6860375
Age: postnatal month 6
Image: S8
Specimen Label: NANCI; Nkx2.1
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7427613
Assay Type: RT-PCR
Annotation Date: 2023-01-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685326
Stage: TS26
Assay Id: MGI:7427624
Age: embryonic day 18.5
Image: 2
Specimen Label: control
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:7427613
Assay Type: RT-PCR
Annotation Date: 2023-01-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1685326
Stage: TS26
Assay Id: MGI:7427624
Age: embryonic day 18.5
Image: 2
Specimen Label: Fbxw7 mutant
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2012-03-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5308279
Age: postnatal week 7
Image: 4J
Note: Expressed in goblet cells at the apical compartment.
Specimen Label: 4J
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:5688948
Age: embryonic day 18.5
Note: Expressed in the surface epithelial cells.
Specimen Label: 1 upper
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5688948
Age: postnatal adult
Specimen Label: 1 lower
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702327
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5688948
Age: postnatal day 1.5
Note: Expressed in the surface epithelial cells.
Specimen Label: S1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702323
Stage: TS23
Assay Id: MGI:5688948
Age: embryonic day 15.5
Specimen Label: not shown
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5308072
Assay Type: Immunohistochemistry
Annotation Date: 2015-10-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1702325
Stage: TS25
Assay Id: MGI:5688948
Age: embryonic day 17.5
Specimen Label: not shown
Detected: false
Specimen Num: 5
GXD Expression
Probe: MGI:1906667
Assay Type: RNA in situ
Annotation Date: 2016-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5770400
Age: postnatal adult
Image: 5B WT
Note: Expression in surface mucosa cells.
Specimen Label: 5B WT
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:1906667
Assay Type: RNA in situ
Annotation Date: 2016-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5770400
Age: postnatal adult
Image: 5B KO
Note: Expression in surface mucosa cells.
Specimen Label: 5B KO
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:1906667
Assay Type: RNA in situ
Annotation Date: 2016-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5770400
Age: postnatal adult
Image: 5A WT
Note: Expression in surface epithelial cells.
Specimen Label: 5A WT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1906667
Assay Type: RNA in situ
Annotation Date: 2016-05-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1702328
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5770400
Age: postnatal adult
Image: 5A KO
Note: Expression in surface epithelial cells.
Specimen Label: 5A KO
Detected: true
Specimen Num: 2