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Search results 1 to 100 out of 122 for Mutyh

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Hits by Pathway

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Type Details Score
Gene
4595 | MUTYH
Type: gene
Organism: human
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Gene
456539 | MUTYH
Type: gene
Organism: chimpanzee
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Gene
513051 | MUTYH
Type: gene
Organism: cattle
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Gene
100856592 | MUTYH
Type: gene
Organism: dog, domestic
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Gene
424594 | MUTYH
Type: gene
Organism: chicken
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Gene
558403 | mutyh
Type: gene
Organism: zebrafish
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Gene
705651 | MUTYH
Type: gene
Organism: macaque, rhesus
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Gene
780292 | mutyh
Type: gene
Organism: frog, western clawed
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Gene
170841 | Mutyh
Type: gene
Organism: rat
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Protein Coding Gene
MGI:1917853 | Mutyh
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
27699246 | J:280608
First Author: Nakatake S
Year: 2016
Journal: JCI Insight
Title: MUTYH promotes oxidative microglial activation and inherited retinal degeneration.
Volume: 1
Issue: 15
Pages: e87781
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Publication
33574380 | J:302628
First Author: Sakamoto H
Year: 2021
Journal: Sci Rep
Title: MUTYH is associated with hepatocarcinogenesis in a non-alcoholic steatohepatitis mouse model.
Volume: 11
Issue: 1
Pages: 3599
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Publication
25638157 | J:302636
First Author: Grasso F
Year: 2015
Journal: Oncotarget
Title: MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation.
Volume: 6
Issue: 10
Pages: 7481-92
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Publication
26109431 | J:302638
First Author: Grasso F
Year: 2015
Journal: Oncotarget
Title: The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
Volume: 6
Issue: 23
Pages: 19671-84
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Publication
28127763 | J:241301
First Author: Pilati C
Year: 2017
Journal: J Pathol
Title: Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.
Volume: 242
Issue: 1
Pages: 10-15
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Publication
23460202 | J:200655
First Author: Turco E
Year: 2013
Journal: Nucleic Acids Res
Title: Understanding the role of the Q338H MUTYH variant in oxidative damage repair.
Volume: 41
Issue: 7
Pages: 4093-103
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Publication
33149810 | J:302643
 
First Author: Sun Q
Year: 2020
Journal: Oxid Med Cell Longev
Title: MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model.
Volume: 2020
Pages: 4828256
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Publication
26711335 | J:302639
First Author: Bjørge MD
Year: 2015
Journal: Cell Rep
Title: Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice.
Volume: 13
Issue: 12
Pages: 2671-8
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Publication
14742662 | J:93680
First Author: Ichinoe A
Year: 2004
Journal: Nucleic Acids Res
Title: Identification and characterization of two forms of mouse MUTYH proteins encoded by alternatively spliced transcripts.
Volume: 32
Issue: 2
Pages: 477-87
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Publication
19435918 | J:148471
First Author: Russo MT
Year: 2009
Journal: Cancer Res
Title: Role of MUTYH and MSH2 in the control of oxidative DNA damage, genetic instability, and tumorigenesis.
Volume: 69
Issue: 10
Pages: 4372-9
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Publication
20706593 | J:302629
First Author: Casorelli I
Year: 2010
Journal: PLoS One
Title: The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis.
Volume: 5
Issue: 8
Pages: e12070
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Publication
30218772 | J:302641
 
First Author: Sakurada A
Year: 2018
Journal: Free Radic Biol Med
Title: An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma.
Volume: 129
Pages: 88-96
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Publication
15681617 | J:96264
First Author: Ushijima Y
Year: 2005
Journal: Nucleic Acids Res
Title: A functional analysis of the DNA glycosylase activity of mouse MUTYH protein excising 2-hydroxyadenine opposite guanine in DNA.
Volume: 33
Issue: 2
Pages: 672-82
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Publication
32001618 | J:286563
First Author: Raetz AG
Year: 2020
Journal: J Biol Chem
Title: The DNA repair enzyme MUTYH potentiates cytotoxicity of the alkylating agent MNNG by interacting with abasic sites.
Volume: 295
Issue: 11
Pages: 3692-3707
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Publication
34970419 | J:324402
 
First Author: Mizuno Y
Year: 2021
Journal: Oxid Med Cell Longev
Title: MUTYH Actively Contributes to Microglial Activation and Impaired Neurogenesis in the Pathogenesis of Alzheimer's Disease.
Volume: 2021
Pages: 8635088
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Publication
15199168 | J:91200
First Author: Tominaga Y
Year: 2004
Journal: Nucleic Acids Res
Title: MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain.
Volume: 32
Issue: 10
Pages: 3198-211
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Publication
17638869 | J:123145
First Author: Sakamoto K
Year: 2007
Journal: Cancer Res
Title: MUTYH-null mice are susceptible to spontaneous and oxidative stress induced intestinal tumorigenesis.
Volume: 67
Issue: 14
Pages: 6599-604
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Publication
25170306 | J:302635
First Author: Isoda T
Year: 2014
Journal: Int J Biol Sci
Title: Abnormality in Wnt signaling is causatively associated with oxidative stress-induced intestinal tumorigenesis in MUTYH-null mice.
Volume: 10
Issue: 8
Pages: 940-7
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Publication
12917422 | J:195260
First Author: Hirano S
Year: 2003
Journal: J Biol Chem
Title: Mutator phenotype of MUTYH-null mouse embryonic stem cells.
Volume: 278
Issue: 40
Pages: 38121-4
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Publication
31505270 | J:302642
 
First Author: Chen J
Year: 2019
Journal: Free Radic Biol Med
Title: Oxidative stress induces different tissue dependent effects on Mutyh-deficient mice.
Volume: 143
Pages: 482-493
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Publication
24296244 | J:211877
 
First Author: Jalland CM
Year: 2014
Journal: Free Radic Biol Med
Title: Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage.
Volume: 68
Pages: 1-7
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Publication
29860357 | J:263644
First Author: Kauppila JHK
Year: 2018
Journal: Nucleic Acids Res
Title: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.
Volume: 46
Issue: 13
Pages: 6642-6669
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Publication
23143307 | J:193978
First Author: Sheng Z
Year: 2012
Journal: J Clin Invest
Title: 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.
Volume: 122
Issue: 12
Pages: 4344-61
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Publication
24732879 | J:210511
 
First Author: Ohno M
Year: 2014
Journal: Sci Rep
Title: 8-oxoguanine causes spontaneous de novo germline mutations in mice.
Volume: 4
Pages: 4689
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Publication
17425590 | J:123869
First Author: Tsuzuki T
Year: 2007
Journal: Cancer Sci
Title: Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.
Volume: 98
Issue: 4
Pages: 465-70
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Protein Coding Gene
MGP_CAROLIEiJ_G0026343 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0028636 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0028597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0028547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0028618 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028332 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1917853 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0027766 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028299 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028447 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028415 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0028549 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028442 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029096 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027492 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0027845 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0028675 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027315 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11160897 | J:74935
First Author: Yang H
Year: 2001
Journal: Nucleic Acids Res
Title: Enhanced activity of adenine-DNA glycosylase (Myh) by apurinic/apyrimidinic endonuclease (Ape1) in mammalian base excision repair of an A/GO mismatch.
Volume: 29
Issue: 3
Pages: 743-52
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Publication
14618256 | J:87116
First Author: Parker AR
Year: 2003
Journal: Cell Mol Life Sci
Title: Human MutY: gene structure, protein functions and interactions, and role in carcinogenesis.
Volume: 60
Issue: 10
Pages: 2064-83
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Publication
25913757 | J:302637
First Author: Kubokura N
Year: 2015
Journal: J Pharmacol Sci
Title: Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo.
Volume: 127
Issue: 4
Pages: 446-55
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Publication
28059467 | J:281454
First Author: Tran AHV
Year: 2017
Journal: J Cell Biochem
Title: MutY DNA Glycosylase Protects Cells From Tumor Necrosis Factor Alpha-Induced Necroptosis.
Volume: 118
Issue: 7
Pages: 1827-1838
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Publication
11948257 | J:75037
First Author: Lee HM
Year: 2002
Journal: J Neurochem
Title: Hypoxia induces mitochondrial DNA damage and stimulates expression of a DNA repair enzyme, the Escherichia coli MutY DNA glycosylase homolog (MYH), in vivo, in the rat brain.
Volume: 80
Issue: 5
Pages: 928-37
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Publication
11805113 | J:75792
First Author: Chang DY
Year: 2002
Journal: J Biol Chem
Title: Functional interaction of MutY homolog with proliferating cell nuclear antigen in fission yeast, Schizosaccharomyces pombe.
Volume: 277
Issue: 14
Pages: 11853-8
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Publication
15533841 | J:94644
First Author: Pope MA
Year: 2005
Journal: DNA Repair (Amst)
Title: DNA damage recognition and repair by the murine MutY homologue.
Volume: 4
Issue: 1
Pages: 91-102
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Publication
15661655 | J:95940
First Author: Pope MA
Year: 2005
Journal: DNA Repair (Amst)
Title: Insight into the functional consequences of hMYH variants associated with colorectal cancer: distinct differences in the adenine glycosylase activity and the response to AP endonucleases of Y150C and G365D murine MYH.
Volume: 4
Issue: 3
Pages: 315-25
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Publication
15231648 | J:91208
First Author: Russo MT
Year: 2004
Journal: Cancer Res
Title: Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases.
Volume: 64
Issue: 13
Pages: 4411-4
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Publication
18258604 | J:133498
First Author: Xie Y
Year: 2008
Journal: Carcinogenesis
Title: Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation.
Volume: 29
Issue: 4
Pages: 722-8
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Publication
15604247 | J:94956
First Author: Sieber OM
Year: 2004
Journal: Cancer Res
Title: Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice.
Volume: 64
Issue: 24
Pages: 8876-81
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Publication
12200441 | J:79878
First Author: Takao M
Year: 2002
Journal: J Biol Chem
Title: A back-up glycosylase in Nth1 knock-out mice is a functional Nei (endonuclease VIII) homologue.
Volume: 277
Issue: 44
Pages: 42205-13
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Publication
16765995 | J:118080
First Author: Larsen E
Year: 2007
Journal: Mutat Res
Title: Organ and cell specificity of base excision repair mutants in mice.
Volume: 614
Issue: 1-2
Pages: 56-68
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Publication
15126346 | J:89742
First Author: Xie Y
Year: 2004
Journal: Cancer Res
Title: Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors.
Volume: 64
Issue: 9
Pages: 3096-102
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Publication
24670930 | J:207962
First Author: Takahashi-Yanaga F
Year: 2014
Journal: Biochem Pharmacol
Title: DIF-1 inhibits tumor growth in vivo reducing phosphorylation of GSK-3β and expressions of cyclin D1 and TCF7L2 in cancer model mice.
Volume: 89
Issue: 3
Pages: 340-8
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Publication
24291244 | J:206144
First Author: Wu L
Year: 2014
Journal: Mol Immunol
Title: Active demethylation of the IL-2 Promoter in CD4+ T cells is mediated by an inducible DNA glycosylase, Myh.
Volume: 58
Issue: 1
Pages: 38-49
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Publication
27581360 | J:239343
First Author: Anjos-Afonso F
Year: 2016
Journal: Blood
Title: Perturbed hematopoiesis in mice lacking ATMIN.
Volume: 128
Issue: 16
Pages: 2017-2021
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Publication
23604909 | J:198500
First Author: Nakahara M
Year: 2013
Journal: Mamm Genome
Title: Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.
Volume: 24
Issue: 5-6
Pages: 228-39
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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