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Search results 1 to 100 out of 287 for Mybpc3

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0.067s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
GXD Expression    
Probe: MGI:3821351
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1750322
Stage: TS22
Assay Id: MGI:3825685
Age: embryonic day 14.5
Image: Additional file 4 Mybpc3
Detected: false
Specimen Num: 1
Publication  
First Author: Lynch TL 4th
Year: 2017
Journal: J Mol Cell Cardiol
Title: Cardiac inflammation in genetic dilated cardiomyopathy caused by MYBPC3 mutation.
Volume: 102
Pages: 83-93
Publication  
First Author: Mearini G
Year: 2014
Journal: Nat Commun
Title: Mybpc3 gene therapy for neonatal cardiomyopathy enables long-term disease prevention in mice.
Volume: 5
Pages: 5515
Publication  
First Author: Barefield D
Year: 2015
Journal: J Mol Cell Cardiol
Title: Haploinsufficiency of MYBPC3 exacerbates the development of hypertrophic cardiomyopathy in heterozygous mice.
Volume: 79
Pages: 234-43
Publication
First Author: Barefield D
Year: 2014
Journal: Am J Physiol Heart Circ Physiol
Title: Contractile dysfunction in a mouse model expressing a heterozygous MYBPC3 mutation associated with hypertrophic cardiomyopathy.
Volume: 306
Issue: 6
Pages: H807-15
Publication
First Author: Fraysse B
Year: 2012
Journal: J Mol Cell Cardiol
Title: Increased myofilament Ca2+ sensitivity and diastolic dysfunction as early consequences of Mybpc3 mutation in heterozygous knock-in mice.
Volume: 52
Issue: 6
Pages: 1299-307
Publication  
First Author: Wijnker PJ
Year: 2016
Journal: J Mol Cell Cardiol
Title: Comparison of the effects of a truncating and a missense MYBPC3 mutation on contractile parameters of engineered heart tissue.
Volume: 97
Pages: 82-92
Publication
First Author: Yang Q
Year: 1999
Journal: Circ Res
Title: In vivo modeling of myosin binding protein C familial hypertrophic cardiomyopathy.
Volume: 85
Issue: 9
Pages: 841-7
Publication  
First Author: Barefield DY
Year: 2019
Journal: J Mol Cell Cardiol
Title: Ablation of the calpain-targeted site in cardiac myosin binding protein-C is cardioprotective during ischemia-reperfusion injury.
Volume: 129
Pages: 236-246
Publication
First Author: Yang Q
Year: 1998
Journal: J Clin Invest
Title: A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy.
Volume: 102
Issue: 7
Pages: 1292-300
Protein
Organism: Mus musculus
Length: 1270  
Fragment?: false
Publication
First Author: Tabish AM
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Association of intronic DNA methylation and hydroxymethylation alterations in the epigenetic etiology of dilated cardiomyopathy.
Volume: 317
Issue: 1
Pages: H168-H180
Publication
First Author: Jiang J
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Cardiac myosin binding protein C regulates postnatal myocyte cytokinesis.
Volume: 112
Issue: 29
Pages: 9046-51
Publication  
First Author: McNamara JW
Year: 2016
Journal: J Mol Cell Cardiol
Title: Ablation of cardiac myosin binding protein-C disrupts the super-relaxed state of myosin in murine cardiomyocytes.
Volume: 94
Pages: 65-71
Publication  
First Author: Singh SR
Year: 2017
Journal: Circ Heart Fail
Title: Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice.
Volume: 10
Issue: 10
Publication
First Author: Najafi A
Year: 2016
Journal: Cardiovasc Res
Title: Selective phosphorylation of PKA targets after β-adrenergic receptor stimulation impairs myofilament function in Mybpc3-targeted HCM mouse model.
Volume: 110
Issue: 2
Pages: 200-14
Publication
First Author: Nixon BR
Year: 2017
Journal: JCI Insight
Title: Alterations in sarcomere function modify the hyperplastic to hypertrophic transition phase of mammalian cardiomyocyte development.
Volume: 2
Issue: 4
Pages: e90656
Publication
First Author: Vignier N
Year: 2009
Journal: Circ Res
Title: Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Volume: 105
Issue: 3
Pages: 239-48
Publication
First Author: Flenner F
Year: 2017
Journal: J Physiol
Title: Diltiazem prevents stress-induced contractile deficits in cardiomyocytes, but does not reverse the cardiomyopathy phenotype in Mybpc3-knock-in mice.
Volume: 595
Issue: 12
Pages: 3987-3999
Publication
First Author: Zhao W
Year: 2015
Journal: PLoS One
Title: A Murine Hypertrophic Cardiomyopathy Model: The DBA/2J Strain.
Volume: 10
Issue: 8
Pages: e0133132
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Ge Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Top-down high-resolution mass spectrometry of cardiac myosin binding protein C revealed that truncation alters protein phosphorylation state.
Volume: 106
Issue: 31
Pages: 12658-63
Publication
First Author: McConnell BK
Year: 1999
Journal: J Clin Invest
Title: Dilated cardiomyopathy in homozygous myosin-binding protein-C mutant mice.
Volume: 104
Issue: 9
Pages: 1235-44
Publication
First Author: Nagayama T
Year: 2007
Journal: Circulation
Title: Control of in vivo left ventricular [correction] contraction/relaxation kinetics by myosin binding protein C: protein kinase A phosphorylation dependent and independent regulation.
Volume: 116
Issue: 21
Pages: 2399-408
Publication
First Author: Sadayappan S
Year: 2005
Journal: Circ Res
Title: Cardiac myosin-binding protein-C phosphorylation and cardiac function.
Volume: 97
Issue: 11
Pages: 1156-63
Publication
First Author: Berul CI
Year: 2001
Journal: Circulation
Title: Ventricular arrhythmia vulnerability in cardiomyopathic mice with homozygous mutant Myosin-binding protein C gene.
Volume: 104
Issue: 22
Pages: 2734-9
Publication
First Author: Sadayappan S
Year: 2009
Journal: Circulation
Title: Cardiac myosin binding protein-C phosphorylation in a {beta}-myosin heavy chain background.
Volume: 119
Issue: 9
Pages: 1253-62
Publication
First Author: Palmer BM
Year: 2004
Journal: Circ Res
Title: Role of cardiac myosin binding protein C in sustaining left ventricular systolic stiffening.
Volume: 94
Issue: 9
Pages: 1249-55
Publication
First Author: Palmer BM
Year: 2004
Journal: Circ Res
Title: Effect of cardiac myosin binding protein-C on mechanoenergetics in mouse myocardium.
Volume: 94
Issue: 12
Pages: 1615-22
Publication
First Author: Harris SP
Year: 2002
Journal: Circ Res
Title: Hypertrophic cardiomyopathy in cardiac myosin binding protein-C knockout mice.
Volume: 90
Issue: 5
Pages: 594-601
Publication
First Author: Colson BA
Year: 2012
Journal: J Mol Cell Cardiol
Title: Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium.
Volume: 53
Issue: 5
Pages: 609-16
Publication
First Author: Brickson S
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: In vivo left ventricular functional capacity is compromised in cMyBP-C null mice.
Volume: 292
Issue: 4
Pages: H1747-54
Publication
First Author: Colson BA
Year: 2008
Journal: Circ Res
Title: Protein kinase A-mediated phosphorylation of cMyBP-C increases proximity of myosin heads to actin in resting myocardium.
Volume: 103
Issue: 3
Pages: 244-51
Publication
First Author: Tong CW
Year: 2008
Journal: Circ Res
Title: Acceleration of crossbridge kinetics by protein kinase A phosphorylation of cardiac myosin binding protein C modulates cardiac function.
Volume: 103
Issue: 9
Pages: 974-82
Publication
First Author: Previs MJ
Year: 2012
Journal: Science
Title: Molecular mechanics of cardiac myosin-binding protein C in native thick filaments.
Volume: 337
Issue: 6099
Pages: 1215-8
Publication
First Author: Cheng Y
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Impaired contractile function due to decreased cardiac myosin binding protein C content in the sarcomere.
Volume: 305
Issue: 1
Pages: H52-65
Publication
First Author: Korte FS
Year: 2003
Journal: Circ Res
Title: Loaded shortening, power output, and rate of force redevelopment are increased with knockout of cardiac myosin binding protein-C.
Volume: 93
Issue: 8
Pages: 752-8
Publication  
First Author: Wang C
Year: 2016
Journal: J Mol Cell Cardiol
Title: Slowing of contractile kinetics by myosin-binding protein C can be explained by its cooperative binding to the thin filament.
Volume: 96
Pages: 2-10
Publication  
First Author: Mamidi R
Year: 2015
Journal: J Mol Cell Cardiol
Title: Molecular effects of the myosin activator omecamtiv mecarbil on contractile properties of skinned myocardium lacking cardiac myosin binding protein-C.
Volume: 85
Pages: 262-72
Publication
First Author: Zoghbi ME
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Three-dimensional structure of vertebrate cardiac muscle myosin filaments.
Volume: 105
Issue: 7
Pages: 2386-90
Publication
First Author: Kensler RW
Year: 2008
Journal: Biophys J
Title: The structure of isolated cardiac Myosin thick filaments from cardiac Myosin binding protein-C knockout mice.
Volume: 94
Issue: 5
Pages: 1707-18
Publication
First Author: Harris SP
Year: 2004
Journal: Circ Res
Title: Binding of myosin binding protein-C to myosin subfragment S2 affects contractility independent of a tether mechanism.
Volume: 95
Issue: 9
Pages: 930-6
Publication
First Author: Colson BA
Year: 2007
Journal: J Mol Biol
Title: Radial displacement of myosin cross-bridges in mouse myocardium due to ablation of myosin binding protein-C.
Volume: 367
Issue: 1
Pages: 36-41
Publication
First Author: Stelzer JE
Year: 2006
Journal: Circ Res
Title: Ablation of cardiac myosin-binding protein-C accelerates stretch activation in murine skinned myocardium.
Volume: 98
Issue: 9
Pages: 1212-8
Publication
First Author: Stelzer JE
Year: 2006
Journal: Biophys J
Title: Ablation of myosin-binding protein-C accelerates force development in mouse myocardium.
Volume: 90
Issue: 11
Pages: 4119-27
Publication
First Author: Gresham KS
Year: 2014
Journal: J Physiol
Title: The contribution of cardiac myosin binding protein-c Ser282 phosphorylation to the rate of force generation and in vivo cardiac contractility.
Volume: 592
Issue: 17
Pages: 3747-65
Publication
First Author: Carrier L
Year: 2004
Journal: Cardiovasc Res
Title: Asymmetric septal hypertrophy in heterozygous cMyBP-C null mice.
Volume: 63
Issue: 2
Pages: 293-304
Publication
First Author: Stathopoulou K
Year: 2016
Journal: FASEB J
Title: S-glutathiolation impairs phosphoregulation and function of cardiac myosin-binding protein C in human heart failure.
Volume: 30
Issue: 5
Pages: 1849-64
Publication
First Author: Pohlmann L
Year: 2007
Journal: Circ Res
Title: Cardiac myosin-binding protein C is required for complete relaxation in intact myocytes.
Volume: 101
Issue: 9
Pages: 928-38
Publication
First Author: Cazorla O
Year: 2006
Journal: Cardiovasc Res
Title: Length and protein kinase A modulations of myocytes in cardiac myosin binding protein C-deficient mice.
Volume: 69
Issue: 2
Pages: 370-80
Publication
First Author: Gedicke-Hornung C
Year: 2013
Journal: EMBO Mol Med
Title: Rescue of cardiomyopathy through U7snRNA-mediated exon skipping in Mybpc3-targeted knock-in mice.
Volume: 5
Issue: 7
Pages: 1128-45
Publication
First Author: Tanaka A
Year: 2014
Journal: J Am Heart Assoc
Title: Endothelin-1 induces myofibrillar disarray and contractile vector variability in hypertrophic cardiomyopathy-induced pluripotent stem cell-derived cardiomyocytes.
Volume: 3
Issue: 6
Pages: e001263
Publication  
First Author: Stöhr A
Year: 2013
Journal: J Mol Cell Cardiol
Title: Contractile abnormalities and altered drug response in engineered heart tissue from Mybpc3-targeted knock-in mice.
Volume: 63
Pages: 189-98
Publication
First Author: Xiao L
Year: 2007
Journal: Biochemistry
Title: PKCepsilon increases phosphorylation of the cardiac myosin binding protein C at serine 302 both in vitro and in vivo.
Volume: 46
Issue: 23
Pages: 7054-61
Publication
First Author: Whitten AE
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Cardiac myosin-binding protein C decorates F-actin: implications for cardiac function.
Volume: 105
Issue: 47
Pages: 18360-5
Publication
First Author: Kasahara H
Year: 1994
Journal: J Clin Invest
Title: Autoimmune myocarditis induced in mice by cardiac C-protein. Cloning of complementary DNA encoding murine cardiac C-protein and partial characterization of the antigenic peptides.
Volume: 94
Issue: 3
Pages: 1026-36
Publication
First Author: Fougerousse F
Year: 1998
Journal: Circ Res
Title: Cardiac myosin binding protein C gene is specifically expressed in heart during murine and human development.
Volume: 82
Issue: 1
Pages: 130-3
Publication
First Author: Nyland LR
Year: 2009
Journal: Biophys J
Title: Cardiac myosin binding protein-C is essential for thick-filament stability and flexural rigidity.
Volume: 96
Issue: 8
Pages: 3273-80
Publication
First Author: Luther PK
Year: 2008
Journal: J Mol Biol
Title: Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle.
Volume: 384
Issue: 1
Pages: 60-72
Publication
First Author: Sadayappan S
Year: 2011
Journal: Circ Res
Title: A critical function for Ser-282 in cardiac Myosin binding protein-C phosphorylation and cardiac function.
Volume: 109
Issue: 2
Pages: 141-50
Publication  
First Author: van Dijk SJ
Year: 2015
Journal: J Mol Cell Cardiol
Title: Normal cardiac contraction in mice lacking the proline-alanine rich region and C1 domain of cardiac myosin binding protein C.
Volume: 88
Pages: 124-32
Publication  
First Author: van Dijk SJ
Year: 2018
Journal: J Mol Cell Cardiol
Title: Point mutations in the tri-helix bundle of the M-domain of cardiac myosin binding protein-C influence systolic duration and delay cardiac relaxation.
Volume: 119
Pages: 116-124
Publication
First Author: Witt CC
Year: 2001
Journal: J Biol Chem
Title: Hypercontractile properties of cardiac muscle fibers in a knock-in mouse model of cardiac myosin-binding protein-C.
Volume: 276
Issue: 7
Pages: 5353-9
Publication
First Author: Doh CY
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: The HCM-causing Y235S cMyBPC mutation accelerates contractile function by altering C1 domain structure.
Volume: 1865
Issue: 3
Pages: 661-677
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185716
Stage: TS16
Assay Id: MGI:2654243
Age: embryonic day 10.0
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185721
Stage: TS21
Assay Id: MGI:2654160
Age: embryonic day 13.0
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185720
Stage: TS20
Assay Id: MGI:2654160
Age: embryonic day 12.0
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3185718
Stage: TS18
Assay Id: MGI:2654160
Age: embryonic day 11.0
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Female
Emaps: EMAPS:3626628
Stage: TS28
Assay Id: MGI:2654194
Age: postnatal
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Female
Emaps: EMAPS:3626628
Stage: TS28
Assay Id: MGI:2654194
Age: postnatal
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3626628
Stage: TS28
Assay Id: MGI:2654186
Age: postnatal adult
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3626628
Stage: TS28
Assay Id: MGI:2654186
Age: postnatal adult
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3626628
Stage: TS28
Assay Id: MGI:2654166
Age: postnatal month 2
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3626628
Stage: TS28
Assay Id: MGI:2654166
Age: postnatal day 7
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3626627
Stage: TS27
Assay Id: MGI:2654166
Age: postnatal day 1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2654186
Age: postnatal adult
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2654186
Age: postnatal adult
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:2654134
Assay Type: Northern blot
Annotation Date: 2003-04-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2654147
Age: postnatal adult
Detected: true
Specimen Num: 3