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Search results 1 to 100 out of 1305 for Mycn

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1.677s

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Hits by Strain

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Type Details Score
Gene
4613 | MYCN
Type: gene
Organism: human
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Gene
459043 | MYCN
Type: gene
Organism: chimpanzee
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Gene
616888 | MYCN
Type: gene
Organism: cattle
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Gene
698699 | MYCN
Type: gene
Organism: macaque, rhesus
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Gene
448649 | mycn
Type: gene
Organism: frog, western clawed
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Gene
252851 | mycn
Type: gene
Organism: zebrafish
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Gene
298894 | Mycn
Type: gene
Organism: rat
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Gene
482978 | MYCN
Type: gene
Organism: dog, domestic
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Gene
421948 | MYCN
Type: gene
Organism: chicken
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Gene
key_80056 | MYCN
Type: gene
Organism: cat, domestic
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Gene
key_25168 | MYCN
Type: gene
Organism: sheep
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Protein Coding Gene
MGI:97357 | Mycn
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
10408 | MYCNOS
Type: gene
Organism: human
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Gene
103752554 | MYCNUT
Type: gene
Organism: human
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Publication
20478998 | J:160518
First Author: Swartling FJ
Year: 2010
Journal: Genes Dev
Title: Pleiotropic role for MYCN in medulloblastoma.
Volume: 24
Issue: 10
Pages: 1059-72
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Publication
22218692 | J:183718
First Author: Chanthery YH
Year: 2012
Journal: Sci Transl Med
Title: Paracrine signaling through MYCN enhances tumor-vascular interactions in neuroblastoma.
Volume: 4
Issue: 115
Pages: 115ra3
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Publication
28459463 | J:247891
First Author: Olsen RR
Year: 2017
Journal: Oncogene
Title: MYCN induces neuroblastoma in primary neural crest cells.
Volume: 36
Issue: 35
Pages: 5075-5082
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Publication
23063798 | J:190992
First Author: Harmelink C
Year: 2013
Journal: Dev Biol
Title: Myocardial Mycn is essential for mouse ventricular wall morphogenesis.
Volume: 373
Issue: 1
Pages: 53-63
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Publication
22789543 | J:191012
First Author: Berry T
Year: 2012
Journal: Cancer Cell
Title: The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma.
Volume: 22
Issue: 1
Pages: 117-30
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Publication
16912192 | J:112163
First Author: Chesler L
Year: 2006
Journal: Cancer Res
Title: Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma.
Volume: 66
Issue: 16
Pages: 8139-46
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Publication
29636449 | J:261937
First Author: Mirzamohammadi F
Year: 2018
Journal: Nat Commun
Title: Distinct molecular pathways mediate Mycn and Myc-regulated miR-17-92 microRNA action in Feingold syndrome mouse models.
Volume: 9
Issue: 1
Pages: 1352
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Publication
25171250 | J:242189
First Author: DeWitt J
Year: 2014
Journal: Dev Neurosci
Title: Ciliary neurotrophic factor reduces the proliferation and promotes the differentiation of TH- MYCN transformed sympathoadrenal progenitors.
Volume: 36
Issue: 5
Pages: 422-31
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Publication
19208763 | J:146444
First Author: Alvarez-Rodríguez R
Year: 2009
Journal: J Cell Sci
Title: Expression of the proneural gene encoding Mash1 suppresses MYCN mitotic activity.
Volume: 122
Issue: Pt 5
Pages: 595-9
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190832
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Mycn
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190832
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Mycn
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190832
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Mycn
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190832
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Mycn
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190832
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Mycn
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190832
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Mycn
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6178596
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190832
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Mycn
Detected: true
Specimen Num: 7
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Publication
34590686 | J:326460
First Author: Yang R
Year: 2022
Journal: Hum Mol Genet
Title: Mycn deficiency underlies the development of orofacial clefts in mice and humans.
Volume: 31
Issue: 5
Pages: 803-815
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Publication
33387268 | J:332187
First Author: Holdhof D
Year: 2021
Journal: Cerebellum
Title: Simultaneous Brg1 Knockout and MYCN Overexpression in Cerebellar Granule Neuron Precursors Is Insufficient to Drive Tumor Formation but Temporarily Enhances their Proliferation and Delays their Migration.
Volume: 20
Issue: 3
Pages: 410-419
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DO Term
DOID:0080888 | spinal ependymoma, MYCN-amplified
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Publication
32820040 | J:303705
First Author: Grunblatt E
Year: 2020
Journal: Genes Dev
Title: MYCN drives chemoresistance in small cell lung cancer while USP7 inhibition can restore chemosensitivity.
Volume: 34
Issue: 17-18
Pages: 1210-1226
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Protein
Q810L7
Organism: Mus musculus/domesticus
Length: 454  
Fragment?: false
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Gene
100609397 | MYCNOS
Type: gene
Organism: chimpanzee
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Gene
112448895 | MYCNOS
Type: gene
Organism: cattle
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Publication
30573562 | J:271076
     
First Author: Kato K
Year: 2018
Journal: J Med Genet
Title: MYCN de novo gain-of-function mutation in a patient with a novel megalencephaly syndrome.
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Publication
25785590 | J:233439
First Author: Ahmad Z
Year: 2015
Journal: PLoS One
Title: Molecular and in vivo characterization of cancer-propagating cells derived from MYCN-dependent medulloblastoma.
Volume: 10
Issue: 3
Pages: e0119834
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Publication
22624711 | J:189301
First Author: Swartling FJ
Year: 2012
Journal: Cancer Cell
Title: Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.
Volume: 21
Issue: 5
Pages: 601-13
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Publication
22340587 | J:181466
First Author: Hogarty MD
Year: 2012
Journal: Cancer Cell
Title: PI3King on MYCN to improve neuroblastoma therapeutics.
Volume: 21
Issue: 2
Pages: 145-7
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Publication
28165337 | J:240402
First Author: Wu N
Year: 2017
Journal: J Clin Invest
Title: A mouse model of MYCN-driven retinoblastoma reveals MYCN-independent tumor reemergence.
Volume: 127
Issue: 3
Pages: 888-898
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Publication
20153925 | J:164102
First Author: Bell E
Year: 2010
Journal: Cancer Lett
Title: MYCN oncoprotein targets and their therapeutic potential.
Volume: 293
Issue: 2
Pages: 144-57
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Publication
32595833 | J:310037
First Author: Yang CL
Year: 2020
Journal: Oncotarget
Title: Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity.
Volume: 11
Issue: 24
Pages: 2357-2371
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Publication
21849159 | J:178560
First Author: Westermark UK
Year: 2011
Journal: Semin Cancer Biol
Title: The MYCN oncogene and differentiation in neuroblastoma.
Volume: 21
Issue: 4
Pages: 256-66
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Publication
36734327 | J:338272
 
First Author: Sendra M
Year: 2023
Journal: Development
Title: Cre recombinase microinjection for single-cell tracing and localised gene targeting.
Volume: 150
Issue: 3
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Publication
33804256 | J:305117
 
First Author: Jiao X
Year: 2021
Journal: Int J Mol Sci
Title: Reduced Granule Cell Proliferation and Molecular Dysregulation in the Cerebellum of Lysosomal Acid Phosphatase 2 (ACP2) Mutant Mice.
Volume: 22
Issue: 6
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Publication
27773673 | J:249255
First Author: Xiao D
Year: 2016
Journal: Mol Cell
Title: Polo-like Kinase-1 Regulates Myc Stabilization and Activates a Feedforward Circuit Promoting Tumor Cell Survival.
Volume: 64
Issue: 3
Pages: 493-506
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Publication
27668798 | J:258583
First Author: King B
Year: 2016
Journal: Nat Immunol
Title: The ubiquitin ligase Huwe1 regulates the maintenance and lymphoid commitment of hematopoietic stem cells.
Volume: 17
Issue: 11
Pages: 1312-1321
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Publication
25557119 | J:278563
First Author: Nakaguro M
Year: 2015
Journal: Cancer Sci
Title: Nucleolar protein PES1 is a marker of neuroblastoma outcome and is associated with neuroblastoma differentiation.
Volume: 106
Issue: 3
Pages: 237-43
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Publication
26829053 | J:230720
First Author: Ueda T
Year: 2016
Journal: Oncogene
Title: ALK(R1275Q) perturbs extracellular matrix, enhances cell invasion and leads to the development of neuroblastoma in cooperation with MYCN.
Volume: 35
Issue: 34
Pages: 4447-58
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Publication
22921766 | J:192942
First Author: Valli E
Year: 2012
Journal: Biochim Biophys Acta
Title: CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells.
Volume: 1819
Issue: 11-12
Pages: 1173-85
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Publication
27728805 | J:236713
First Author: Dardenne E
Year: 2016
Journal: Cancer Cell
Title: N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer.
Volume: 30
Issue: 4
Pages: 563-577
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Publication
27618649 | J:240517
First Author: Tavana O
Year: 2016
Journal: Nat Med
Title: HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma.
Volume: 22
Issue: 10
Pages: 1180-1186
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Publication
20537458 | J:161374
First Author: Varlakhanova NV
Year: 2010
Journal: Differentiation
Title: myc maintains embryonic stem cell pluripotency and self-renewal.
Volume: 80
Issue: 1
Pages: 9-19
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Publication
- | J:14305
 
First Author: Klett C
Year: 1991
Journal: Mouse Genome
Title: Mapping of Nmyc-1 to mouse Chromosome 12, band A3/B.
Volume: 89
Pages: 275
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Publication
22164278 | J:182261
First Author: Terrile M
Year: 2011
Journal: PLoS One
Title: miRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs.
Volume: 6
Issue: 12
Pages: e28356
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Publication
33410138 | J:304357
First Author: Seya D
Year: 2021
Journal: Dev Growth Differ
Title: A role of Hey2 transcription factor for right ventricle development through regulation of Tbx2-Mycn pathway during cardiac morphogenesis.
Volume: 63
Issue: 1
Pages: 82-92
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Publication
30642836 | J:272568
 
First Author: Muñoz-Martín N
Year: 2019
Journal: Development
Title: Myc is dispensable for cardiomyocyte development but rescues Mycn-deficient hearts through functional replacement and cell competition.
Volume: 146
Issue: 3
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Publication
22907436 | J:199983
First Author: Calao M
Year: 2013
Journal: Oncogene
Title: Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation.
Volume: 32
Issue: 31
Pages: 3616-26
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Publication
30061166 | J:270575
 
First Author: Mastromina I
Year: 2018
Journal: Development
Title: Myc activity is required for maintenance of the neuromesodermal progenitor signalling network and for segmentation clock gene oscillations in mouse.
Volume: 145
Issue: 14
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Publication
34716243 | J:330416
First Author: Li J
Year: 2021
Journal: J Am Soc Nephrol
Title: Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance.
Volume: 32
Issue: 11
Pages: 2815-2833
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Publication
31042497 | J:278332
First Author: Sun Q
Year: 2019
Journal: Dev Biol
Title: SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.
Volume: 452
Issue: 1
Pages: 1-7
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Publication
23430699 | J:198307
First Author: Puissant A
Year: 2013
Journal: Cancer Discov
Title: Targeting MYCN in neuroblastoma by BET bromodomain inhibition.
Volume: 3
Issue: 3
Pages: 308-23
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Publication
21307096 | J:170488
First Author: Blank MC
Year: 2011
Journal: Development
Title: Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis.
Volume: 138
Issue: 6
Pages: 1207-16
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Publication
25175806 | J:214800
First Author: Gustafson WC
Year: 2014
Journal: Cancer Cell
Title: Drugging MYCN through an allosteric transition in Aurora kinase A.
Volume: 26
Issue: 3
Pages: 414-427
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Protein Coding Gene
MGP_CAROLIEiJ_G0017621 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019604 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019570 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97357 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019995 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018907 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019323 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019436 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019427 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019507 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019461 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020034 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018673 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029377 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018463 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3513190 | J:8219
First Author: DePinho RA
Year: 1986
Journal: Proc Natl Acad Sci U S A
Title: Structure and expression of the murine N-myc gene.
Volume: 83
Issue: 6
Pages: 1827-31
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Publication
3015591 | J:8353
First Author: Taya Y
Year: 1986
Journal: EMBO J
Title: Nucleotide sequence of the coding region of the mouse N-myc gene.
Volume: 5
Issue: 6
Pages: 1215-9
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Publication
3287334 | J:9196
First Author: Katoh K
Year: 1988
Journal: Nucleic Acids Res
Title: Complete nucleotide sequence and exon-intron boundaries of the 5' non-coding region of the mouse N-myc gene.
Volume: 16
Issue: 8
Pages: 3589
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Publication
25437558 | J:217469
First Author: Hackett CS
Year: 2014
Journal: Cell Rep
Title: Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.
Volume: 9
Issue: 3
Pages: 1034-46
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Publication
30054041 | J:273418
First Author: Kawakubo N
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Natural antibody against neuroblastoma of TH-MYCN transgenic mice does not correlate with spontaneous regression.
Volume: 503
Issue: 3
Pages: 1666-1673
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Publication
22879379 | J:196015
First Author: Sun R
Year: 2012
Journal: Nucleic Acids Res
Title: Inducible and reversible regulation of endogenous gene in mouse.
Volume: 40
Issue: 21
Pages: e166
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Publication
9635194 | J:67930
First Author: Nagy A
Year: 1998
Journal: Curr Biol
Title: Dissecting the role of N-myc in development using a single targeting vector to generate a series of alleles.
Volume: 8
Issue: 11
Pages: 661-4
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Publication
20530674 | J:161601
First Author: Heine VM
Year: 2010
Journal: Cancer Res
Title: Dexamethasone destabilizes Nmyc to inhibit the growth of hedgehog-associated medulloblastoma.
Volume: 70
Issue: 13
Pages: 5220-5
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Publication
1931830 | J:76279
First Author: Sawai S
Year: 1991
Journal: New Biol
Title: Embryonic lethality resulting from disruption of both N-myc alleles in mouse zygotes.
Volume: 3
Issue: 9
Pages: 861-9
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Publication
8404543 | J:11859
First Author: Sawai S
Year: 1993
Journal: Development
Title: Defects of embryonic organogenesis resulting from targeted disruption of the N-myc gene in the mouse.
Volume: 117
Issue: 4
Pages: 1445-55
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Publication
1459450 | J:3413
First Author: Charron J
Year: 1992
Journal: Genes Dev
Title: Embryonic lethality in mice homozygous for a targeted disruption of the N-myc gene.
Volume: 6
Issue: 12A
Pages: 2248-57
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Publication
24397388 | J:278529
First Author: Ma M
Year: 2014
Journal: Dev Growth Differ
Title: Dynamic expression of N-myc in mouse embryonic development using an enhanced green fluorescent protein reporter gene in the N-myc locus.
Volume: 56
Issue: 2
Pages: 152-60
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Publication
1577267 | J:973
First Author: Moens CB
Year: 1992
Journal: Genes Dev
Title: A targeted mutation reveals a role for N-myc in branching morphogenesis in the embryonic mouse lung.
Volume: 6
Issue: 5
Pages: 691-704
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Publication
10837121 | J:107691
First Author: Bates CM
Year: 2000
Journal: Dev Biol
Title: Role of N-myc in the developing mouse kidney.
Volume: 222
Issue: 2
Pages: 317-25
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Publication
1701023 | J:48400
First Author: Stanton BR
Year: 1990
Journal: Mol Cell Biol
Title: Germ line transmission of an inactive N-myc allele generated by homologous recombination in mouse embryonic stem cells.
Volume: 10
Issue: 12
Pages: 6755-8
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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