|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 2080 for Myh6

<< First    < Previous  |  Next >    Last >>
0.044s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Yan J
Year: 2015
Journal: PLoS One
Title: A Murine Myh6MerCreMer Knock-In Allele Specifically Mediates Temporal Genetic Deletion in Cardiomyocytes after Tamoxifen Induction.
Volume: 10
Issue: 7
Pages: e0133472
Publication
First Author: Jiang J
Year: 2013
Journal: Science
Title: Allele-specific silencing of mutant Myh6 transcripts in mice suppresses hypertrophic cardiomyopathy.
Volume: 342
Issue: 6154
Pages: 111-4
Publication
First Author: Han P
Year: 2016
Journal: Biochim Biophys Acta
Title: Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.
Volume: 1863
Issue: 7 Pt B
Pages: 1772-81
Publication  
First Author: Pugach EK
Year: 2015
Journal: J Mol Cell Cardiol
Title: Prolonged Cre expression driven by the α-myosin heavy chain promoter can be cardiotoxic.
Volume: 86
Pages: 54-61
Publication
First Author: Da Silva F
Year: 2018
Journal: Dev Biol
Title: Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4.
Volume: 441
Issue: 1
Pages: 42-51
Publication
First Author: Zhao C
Year: 2014
Journal: Development
Title: Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation.
Volume: 141
Issue: 2
Pages: 281-95
Publication
First Author: Li H
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Genetic modification of survival in tissue-specific knockout mice with mitochondrial cardiomyopathy.
Volume: 97
Issue: 7
Pages: 3467-72
Publication
First Author: Misra C
Year: 2014
Journal: Hum Mol Genet
Title: Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation.
Volume: 23
Issue: 19
Pages: 5025-35
Publication
First Author: Li Y
Year: 2019
Journal: Circ Res
Title: Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages.
Volume: 125
Issue: 3
Pages: 343-355
Publication
First Author: Reynolds JO
Year: 2013
Journal: Cardiovasc Res
Title: Junctophilin-2 is necessary for T-tubule maturation during mouse heart development.
Volume: 100
Issue: 1
Pages: 44-53
Publication
First Author: Tian Y
Year: 2015
Journal: Sci Transl Med
Title: A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice.
Volume: 7
Issue: 279
Pages: 279ra38
Publication
First Author: Lai L
Year: 2008
Journal: Genes Dev
Title: Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.
Volume: 22
Issue: 14
Pages: 1948-61
Publication
First Author: Mysliwiec MR
Year: 2011
Journal: J Biol Chem
Title: Endothelial Jarid2/Jumonji is required for normal cardiac development and proper Notch1 expression.
Volume: 286
Issue: 19
Pages: 17193-204
Publication
First Author: Qiu Z
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: c-Abl tyrosine kinase regulates cardiac growth and development.
Volume: 107
Issue: 3
Pages: 1136-41
Publication
First Author: Banerjee I
Year: 2012
Journal: Circ Res
Title: Thymosin beta 4 is dispensable for murine cardiac development and function.
Volume: 110
Issue: 3
Pages: 456-64
Publication
First Author: Yuan B
Year: 2014
Journal: Am J Pathol
Title: A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.
Volume: 184
Issue: 7
Pages: 1967-80
Publication
First Author: Cho E
Year: 2019
Journal: J Biol Chem
Title: Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.
Volume: 294
Issue: 13
Pages: 4981-4996
Publication
First Author: Kratsios P
Year: 2010
Journal: Circ Res
Title: Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart.
Volume: 106
Issue: 3
Pages: 559-72
Publication
First Author: Spitler KM
Year: 2017
Journal: Am J Physiol Heart Circ Physiol
Title: Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.
Volume: 312
Issue: 4
Pages: H768-H780
Publication
First Author: Nguyen AT
Year: 2011
Journal: Genes Dev
Title: DOT1L regulates dystrophin expression and is critical for cardiac function.
Volume: 25
Issue: 3
Pages: 263-74
Publication
First Author: Guo Y
Year: 2019
Journal: Circulation
Title: Cardiomyocyte Homeodomain-Interacting Protein Kinase 2 Maintains Basal Cardiac Function via Extracellular Signal-Regulated Kinase Signaling.
Volume: 140
Issue: 22
Pages: 1820-1833
Publication
First Author: Ye B
Year: 2015
Journal: J Mol Cell Cardiol
Title: APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.
Volume: 89
Issue: Pt B
Pages: 287-96
Publication
First Author: Zeisberg EM
Year: 2005
Journal: J Clin Invest
Title: Morphogenesis of the right ventricle requires myocardial expression of Gata4.
Volume: 115
Issue: 6
Pages: 1522-31
Publication
First Author: Misra C
Year: 2012
Journal: PLoS Genet
Title: Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.
Volume: 8
Issue: 5
Pages: e1002690
Publication
First Author: Yin Z
Year: 2008
Journal: Circulation
Title: Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.
Volume: 117
Issue: 11
Pages: 1414-22
Publication
First Author: Kim GE
Year: 2015
Journal: Cardiovasc Res
Title: LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation.
Volume: 108
Issue: 1
Pages: 197-208
Publication
First Author: Zou J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Volume: 115
Issue: 17
Pages: E4101-E4110
Publication
First Author: Gómez-Del Arco P
Year: 2016
Journal: Cell Metab
Title: The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis.
Volume: 23
Issue: 5
Pages: 881-92
Publication
First Author: Lowey S
Year: 2013
Journal: J Biol Chem
Title: Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.
Volume: 288
Issue: 21
Pages: 14780-7
Publication
First Author: Lowey S
Year: 2008
Journal: J Biol Chem
Title: Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.
Volume: 283
Issue: 29
Pages: 20579-89
Allele
Name: transgene insertion 1, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Protein
Organism: Mus musculus
Length: 1003  
Fragment?: true
Protein
Organism: Mus musculus
Length: 1004  
Fragment?: true
Strain
Attribute String: transgenic, mutant stock
Publication
First Author: Subramaniam A
Year: 1991
Journal: J Biol Chem
Title: Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice.
Volume: 266
Issue: 36
Pages: 24613-20
Publication
First Author: Gulick J
Year: 1991
Journal: J Biol Chem
Title: Isolation and characterization of the mouse cardiac myosin heavy chain genes.
Volume: 266
Issue: 14
Pages: 9180-5
Publication
First Author: Granados-Riveron JT
Year: 2010
Journal: Hum Mol Genet
Title: Alpha-cardiac myosin heavy chain (MYH6) mutations affecting myofibril formation are associated with congenital heart defects.
Volume: 19
Issue: 20
Pages: 4007-16
Publication
First Author: Lv H
Year: 2011
Journal: J Clin Invest
Title: Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans.
Volume: 121
Issue: 4
Pages: 1561-73
Publication
First Author: Kuwabara Y
Year: 2020
Journal: Commun Biol
Title: Lionheart LincRNA alleviates cardiac systolic dysfunction under pressure overload.
Volume: 3
Issue: 1
Pages: 434
ncRNA Gene
Type: ncRNA_gene
Organism: Mus musculus
Publication
First Author: van Rooij E
Year: 2007
Journal: Science
Title: Control of stress-dependent cardiac growth and gene expression by a microRNA.
Volume: 316
Issue: 5824
Pages: 575-9
Publication
First Author: van Rooij E
Year: 2009
Journal: Dev Cell
Title: A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance.
Volume: 17
Issue: 5
Pages: 662-73
Publication
First Author: Callis TE
Year: 2009
Journal: J Clin Invest
Title: MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.
Volume: 119
Issue: 9
Pages: 2772-86
Publication  
First Author: Yan J
Year: 2016
Journal: J Mol Cell Cardiol
Title: A series of robust genetic indicators for definitive identification of cardiomyocytes.
Volume: 97
Pages: 278-85
Publication
First Author: Trivedi CM
Year: 2007
Journal: Nat Med
Title: Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.
Volume: 13
Issue: 3
Pages: 324-31
Publication
First Author: Pandya K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
Volume: 105
Issue: 35
Pages: 13063-8
Publication
First Author: Zhang S
Year: 2019
Journal: Cardiovasc Res
Title: WD40 repeat and FYVE domain containing 3 is essential for cardiac development.
Volume: 115
Issue: 8
Pages: 1320-1331
Publication
First Author: Davis J
Year: 2016
Journal: Cell
Title: A Tension-Based Model Distinguishes Hypertrophic versus Dilated Cardiomyopathy.
Volume: 165
Issue: 5
Pages: 1147-1159
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Quinn-Laquer BK
Year: 1992
Journal: Genomics
Title: Characterization of the allelic differences in the mouse cardiac alpha-myosin heavy chain coding sequence.
Volume: 13
Issue: 1
Pages: 176-88
Publication
First Author: Lam L
Year: 2010
Journal: J Mol Cell Cardiol
Title: Differential protein expression profiling of myocardial tissue in a mouse model of hypertrophic cardiomyopathy.
Volume: 48
Issue: 5
Pages: 1014-22
Publication
First Author: Jones WK
Year: 1996
Journal: J Clin Invest
Title: Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart.
Volume: 98
Issue: 8
Pages: 1906-17
Publication
First Author: Palmer BM
Year: 2004
Journal: Am J Physiol Heart Circ Physiol
Title: Differential cross-bridge kinetics of FHC myosin mutations R403Q and R453C in heterozygous mouse myocardium.
Volume: 287
Issue: 1
Pages: H91-9
Publication
First Author: Green EM
Year: 2016
Journal: Science
Title: A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.
Volume: 351
Issue: 6273
Pages: 617-21
Publication
First Author: Debold EP
Year: 2007
Journal: Am J Physiol Heart Circ Physiol
Title: Hypertrophic and dilated cardiomyopathy mutations differentially affect the molecular force generation of mouse alpha-cardiac myosin in the laser trap assay.
Volume: 293
Issue: 1
Pages: H284-91
Publication
First Author: Blankenburg R
Year: 2014
Journal: Circ Res
Title: β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations.
Volume: 115
Issue: 2
Pages: 227-37
Publication
First Author: Toepfer CN
Year: 2020
Journal: Circulation
Title: Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy.
Volume: 141
Issue: 10
Pages: 828-842
Publication
First Author: Geisterfer-Lowrance AA
Year: 1996
Journal: Science
Title: A mouse model of familial hypertrophic cardiomyopathy.
Volume: 272
Issue: 5262
Pages: 731-4
Publication
First Author: Schmitt JP
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.
Volume: 103
Issue: 39
Pages: 14525-30
Publication
First Author: Wolf CM
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Somatic events modify hypertrophic cardiomyopathy pathology and link hypertrophy to arrhythmia.
Volume: 102
Issue: 50
Pages: 18123-8
Publication
First Author: Huang Y
Year: 2020
Journal: Cardiovasc Res
Title: Fropofol prevents disease progression in mice with hypertrophic cardiomyopathy.
Volume: 116
Issue: 6
Pages: 1175-1185
Publication
First Author: Gao WD
Year: 1999
Journal: J Clin Invest
Title: Altered cardiac excitation-contraction coupling in mutant mice with familial hypertrophic cardiomyopathy.
Volume: 103
Issue: 5
Pages: 661-6
Publication
First Author: Hardt SE
Year: 2002
Journal: Circulation
Title: Accelerated cardiomyopathy in mice with overexpression of cardiac G(s)alpha and a missense mutation in the alpha-myosin heavy chain.
Volume: 105
Issue: 5
Pages: 614-20
Publication
First Author: Hinson JT
Year: 2016
Journal: Cell Rep
Title: Integrative Analysis of PRKAG2 Cardiomyopathy iPS and Microtissue Models Identifies AMPK as a Regulator of Metabolism, Survival, and Fibrosis.
Volume: 17
Issue: 12
Pages: 3292-3304
Publication
First Author: Semsarian C
Year: 2001
Journal: J Mol Cell Cardiol
Title: A polymorphic modifier gene alters the hypertrophic response in a murine model of familial hypertrophic cardiomyopathy.
Volume: 33
Issue: 11
Pages: 2055-60
Publication
First Author: Blanchard E
Year: 1999
Journal: Circ Res
Title: Altered crossbridge kinetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
Volume: 84
Issue: 4
Pages: 475-83
Publication
First Author: Chuan P
Year: 2012
Journal: Biophys J
Title: Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy.
Volume: 102
Issue: 12
Pages: 2782-90
Publication
First Author: Viola HM
Year: 2016
Journal: JACC Basic Transl Sci
Title: The Role of the L-Type Ca2+ Channel in Altered Metabolic Activity in a Murine Model of Hypertrophic Cardiomyopathy.
Volume: 1
Issue: 1-2
Pages: 61-72
Publication
First Author: Berul CI
Year: 1997
Journal: J Clin Invest
Title: Electrophysiological abnormalities and arrhythmias in alpha MHC mutant familial hypertrophic cardiomyopathy mice.
Volume: 99
Issue: 4
Pages: 570-6
Publication
First Author: Georgakopoulos D
Year: 1999
Journal: Nat Med
Title: The pathogenesis of familial hypertrophic cardiomyopathy: early and evolving effects from an alpha-cardiac myosin heavy chain missense mutation.
Volume: 5
Issue: 3
Pages: 327-30
Publication
First Author: Kim JB
Year: 2007
Journal: Science
Title: Polony multiplex analysis of gene expression (PMAGE) in mouse hypertrophic cardiomyopathy.
Volume: 316
Issue: 5830
Pages: 1481-4
Publication  
First Author: Hueneke R
Year: 2017
Journal: J Mol Cell Cardiol
Title: Early remodeling of repolarizing K+ currents in the αMHC403/+ mouse model of familial hypertrophic cardiomyopathy.
Volume: 103
Pages: 93-101
Publication
First Author: Kim SJ
Year: 1999
Journal: Am J Physiol
Title: An alpha-cardiac myosin heavy chain gene mutation impairs contraction and relaxation function of cardiac myocytes.
Volume: 276
Issue: 5
Pages: H1780-7
Publication
First Author: Palmer BM
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex.
Volume: 294
Issue: 4
Pages: H1939-47
Publication
First Author: Schmitt JP
Year: 2003
Journal: Circulation
Title: Consequences of pressure overload on sarcomere protein mutation-induced hypertrophic cardiomyopathy.
Volume: 108
Issue: 9
Pages: 1133-8
Publication
First Author: Semsarian C
Year: 2002
Journal: J Clin Invest
Title: The L-type calcium channel inhibitor diltiazem prevents cardiomyopathy in a mouse model.
Volume: 109
Issue: 8
Pages: 1013-20
Publication
First Author: Bevilacqua LM
Year: 1999
Journal: Pediatr Res
Title: QT dispersion in alpha-myosin heavy-chain familial hypertrophic cardiomyopathy mice.
Volume: 45
Issue: 5 Pt 1
Pages: 643-7
Publication
First Author: Fatkin D
Year: 2000
Journal: J Clin Invest
Title: An abnormal Ca(2+) response in mutant sarcomere protein-mediated familial hypertrophic cardiomyopathy.
Volume: 106
Issue: 11
Pages: 1351-9