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Search results 1 to 100 out of 1211 for Myh7

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1.421s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Parlakian A
Year: 2004
Journal: Mol Cell Biol
Title: Targeted inactivation of serum response factor in the developing heart results in myocardial defects and embryonic lethality.
Volume: 24
Issue: 12
Pages: 5281-9
Publication
First Author: van Berlo JH
Year: 2010
Journal: Circ Res
Title: The transcription factor GATA-6 regulates pathological cardiac hypertrophy.
Volume: 107
Issue: 8
Pages: 1032-40
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
GXD Expression
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: S3D MYH7
Note: Expression in slow muscle fibers.
Detected: true
Specimen Num: 6
Publication
First Author: Angrisano T
Year: 2014
Journal: PLoS One
Title: Epigenetic switch at atp2a2 and myh7 gene promoters in pressure overload-induced heart failure.
Volume: 9
Issue: 9
Pages: e106024
GXD Expression
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: 1F MYH7 Mettl21c -/-
Note: Expression in slow muscle fibers.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: S1K MYH7 Wild type
Note: Expression in slow muscle fibers.
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: S1K MYH7 Mettl21c +/-
Note: Expression in slow muscle fibers.
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: S1K MYH7 Mettl21c -/-
Note: Expression in slow muscle fibers.
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: 1F MYH7 Mettl21c +/-
Note: Expression in slow muscle fibers.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: 5F MYH7 wild type (upper)
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: 5F MYH7 wild type (lower)
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: 5F MYH7 Mettl21c -/- (upper)
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:6458517
Assay Type: Immunohistochemistry
Annotation Date: 2020-09-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3578628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6458580
Age: postnatal adult
Image: 5F MYH7 Mettl21c -/- (lower)
Detected: true
Specimen Num: 10
Allele
Name: transgene insertion 1, Zhenlin Li
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Genotype
Symbol: Srf/Srf Tg(Myh7-cre)1Zli/?
Background: involves: 129/Sv * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Wang JH
Year: 2015
Journal: Dev Biol
Title: Heterogeneous activation of a slow myosin gene in proliferating myoblasts and differentiated single myofibers.
Volume: 402
Issue: 1
Pages: 72-80
Genotype
Symbol: Tg(CAG-cat,-lacZ)34Pva/? Tg(Myh7-cre)1Zli/?
Background: involves: C57BL/6 * DBA/2
Zygosity: cn
Has Mutant Allele: true
Allele
Name: transgene insertion 1, Jeffery D Molkentin
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Publication
First Author: Parsons SA
Year: 2004
Journal: J Biol Chem
Title: Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy.
Volume: 279
Issue: 25
Pages: 26192-200
Publication
First Author: Accornero F
Year: 2015
Journal: Mol Cell Biol
Title: Genetic Analysis of Connective Tissue Growth Factor as an Effector of Transforming Growth Factor β Signaling and Cardiac Remodeling.
Volume: 35
Issue: 12
Pages: 2154-64
Publication
First Author: Edwards MA
Year: 2015
Journal: J Appl Physiol (1985)
Title: The Q510E mutation in Shp2 perturbs heart valve development by increasing cell migration.
Volume: 118
Issue: 1
Pages: 124-31
Publication
First Author: Dorn LE
Year: 2019
Journal: Circulation
Title: The N6-Methyladenosine mRNA Methylase METTL3 Controls Cardiac Homeostasis and Hypertrophy.
Volume: 139
Issue: 4
Pages: 533-545
Publication    
First Author: Boyer JG
Year: 2019
Journal: JCI Insight
Title: ERK1/2 signaling induces skeletal muscle slow fiber-type switching and reduces muscular dystrophy disease severity.
Volume: 5
Publication
First Author: Sengupta A
Year: 2011
Journal: J Biol Chem
Title: FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress.
Volume: 286
Issue: 9
Pages: 7468-78
Publication
First Author: Chen Y
Year: 2012
Journal: Circ Res
Title: Mitofusin 2-containing mitochondrial-reticular microdomains direct rapid cardiomyocyte bioenergetic responses via interorganelle Ca(2+) crosstalk.
Volume: 111
Issue: 7
Pages: 863-75
Publication
First Author: Guo X
Year: 2017
Journal: Circulation
Title: Cardioprotective Role of Tumor Necrosis Factor Receptor-Associated Factor 2 by Suppressing Apoptosis and Necroptosis.
Volume: 136
Issue: 8
Pages: 729-742
Publication    
First Author: Malek Mohammadi M
Year: 2019
Journal: JCI Insight
Title: Induction of cardiomyocyte proliferation and angiogenesis protects neonatal mice from pressure overload-associated maladaptation.
Volume: 5
Publication
First Author: Li L
Year: 2014
Journal: Circulation
Title: Transforming growth factor β-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling.
Volume: 130
Issue: 24
Pages: 2162-72
Publication
First Author: van Berlo JH
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo.
Volume: 108
Issue: 30
Pages: 12331-6
Publication
First Author: Rindler TN
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Knockout of the Na,K-ATPase α2-isoform in cardiac myocytes delays pressure overload-induced cardiac dysfunction.
Volume: 304
Issue: 8
Pages: H1147-58
Publication
First Author: Sutherland MJ
Year: 2013
Journal: Hum Mol Genet
Title: Zic3 is required in the migrating primitive streak for node morphogenesis and left-right patterning.
Volume: 22
Issue: 10
Pages: 1913-23
Publication
First Author: Liu R
Year: 2016
Journal: PLoS One
Title: Nemo-Like Kinase (NLK) Is a Pathological Signaling Effector in the Mouse Heart.
Volume: 11
Issue: 10
Pages: e0164897
Publication
First Author: Song M
Year: 2014
Journal: Circ Res
Title: Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy.
Volume: 115
Issue: 3
Pages: 348-53
Publication
First Author: Oka T
Year: 2006
Journal: Circ Res
Title: Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability.
Volume: 98
Issue: 6
Pages: 837-45
Publication  
First Author: Zhang Z
Year: 2016
Journal: Circ Heart Fail
Title: Postnatal Loss of Kindlin-2 Leads to Progressive Heart Failure.
Volume: 9
Issue: 8
Publication
First Author: Khalil H
Year: 2019
Journal: JCI Insight
Title: Cell-specific ablation of Hsp47 defines the collagen-producing cells in the injured heart
Volume: 4
Issue: 15
Pages: e128722
Publication
First Author: Sengupta A
Year: 2012
Journal: Dev Dyn
Title: FoxO1 is required in endothelial but not myocardial cell lineages during cardiovascular development.
Volume: 241
Issue: 4
Pages: 803-13
Publication
First Author: Chakraborty S
Year: 2012
Journal: Dev Biol
Title: Tbx20 regulation of cardiac cell proliferation and lineage specialization during embryonic and fetal development in vivo.
Volume: 363
Issue: 1
Pages: 234-46
Publication
First Author: van Berlo JH
Year: 2013
Journal: PLoS One
Title: Parsing the roles of the transcription factors GATA-4 and GATA-6 in the adult cardiac hypertrophic response.
Volume: 8
Issue: 12
Pages: e84591
Publication
First Author: Heineke J
Year: 2007
Journal: J Clin Invest
Title: Cardiomyocyte GATA4 functions as a stress-responsive regulator of angiogenesis in the murine heart.
Volume: 117
Issue: 11
Pages: 3198-210
Publication
First Author: Malek Mohammadi M
Year: 2017
Journal: EMBO Mol Med
Title: The transcription factor GATA4 promotes myocardial regeneration in neonatal mice.
Volume: 9
Issue: 2
Pages: 265-279
Allele
Name: myosin, heavy polypeptide 7, cardiac muscle, beta; targeted mutation 1, Wellcome Trust Sanger Institute
Allele Type: Targeted
Attribute String: Conditional ready, Inducible, Recombinase, Reporter
Publication categories: ProxyCollection
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Strain
Attribute String: mutant strain, coisogenic, targeted mutation
Genotype
Symbol: Gata4/Gata4 Tg(Myh7-cre)1Jmk/?
Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gata4/Gata4 Tg(Myh6-Map2k1*)1Jmol/? Tg(Myh7-cre)1Jmk/?
Background: involves: 129S1/Sv * 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Zic3/? Tg(Myh7-cre)1Jmk/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/? Tg(Myh7-cre)1Jmk/?
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus
Length: 1935  
Fragment?: false
Publication
First Author: Krenz M
Year: 2003
Journal: J Biol Chem
Title: Analysis of myosin heavy chain functionality in the heart.
Volume: 278
Issue: 19
Pages: 17466-74
Publication
First Author: Lowey S
Year: 2013
Journal: J Biol Chem
Title: Transgenic mouse α- and β-cardiac myosins containing the R403Q mutation show isoform-dependent transient kinetic differences.
Volume: 288
Issue: 21
Pages: 14780-7
Publication
First Author: Lowey S
Year: 2008
Journal: J Biol Chem
Title: Functional effects of the hypertrophic cardiomyopathy R403Q mutation are different in an alpha- or beta-myosin heavy chain backbone.
Volume: 283
Issue: 29
Pages: 20579-89
Publication
First Author: Gifford CA
Year: 2019
Journal: Science
Title: Oligogenic inheritance of a human heart disease involving a genetic modifier.
Volume: 364
Issue: 6443
Pages: 865-870
Publication
First Author: Zhang P
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Mammalian target of rapamycin is essential for cardiomyocyte survival and heart development in mice.
Volume: 452
Issue: 1
Pages: 53-9
Publication
First Author: Ignacio DL
Year: 2017
Journal: Thyroid
Title: Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function.
Volume: 27
Issue: 4
Pages: 577-586
Publication
First Author: Ku MC
Year: 2021
Journal: J Cardiovasc Magn Reson
Title: Cardiovascular magnetic resonance detects microvascular dysfunction in a mouse model of hypertrophic cardiomyopathy.
Volume: 23
Issue: 1
Pages: 63
Publication
First Author: Pandya K
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Discordant on/off switching of gene expression in myocytes during cardiac hypertrophy in vivo.
Volume: 105
Issue: 35
Pages: 13063-8
Publication
First Author: Han P
Year: 2014
Journal: Nature
Title: A long noncoding RNA protects the heart from pathological hypertrophy.
Volume: 514
Issue: 7520
Pages: 102-106
Publication
First Author: Cho E
Year: 2019
Journal: J Biol Chem
Title: Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.
Volume: 294
Issue: 13
Pages: 4981-4996
Publication
First Author: Fakruddin M
Year: 2018
Journal: Cell Rep
Title: Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease.
Volume: 22
Issue: 2
Pages: 482-496
Publication
First Author: Lewandowski SL
Year: 2014
Journal: Hum Mol Genet
Title: Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.
Volume: 23
Issue: 14
Pages: 3801-9
Publication
First Author: Fujita J
Year: 2017
Journal: Cell Rep
Title: Ronin Governs Early Heart Development by Controlling Core Gene Expression Programs.
Volume: 21
Issue: 6
Pages: 1562-1573
Publication
First Author: Zeisberg EM
Year: 2005
Journal: J Clin Invest
Title: Morphogenesis of the right ventricle requires myocardial expression of Gata4.
Volume: 115
Issue: 6
Pages: 1522-31
Publication
First Author: Ye B
Year: 2015
Journal: J Mol Cell Cardiol
Title: APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.
Volume: 89
Issue: Pt B
Pages: 287-96
Publication
First Author: Misra C
Year: 2012
Journal: PLoS Genet
Title: Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.
Volume: 8
Issue: 5
Pages: e1002690
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Pandya K
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo.
Volume: 103
Issue: 45
Pages: 16864-9
Publication
First Author: Birch CL
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: Sex dimorphisms of crossbridge cycling kinetics in transgenic hypertrophic cardiomyopathy mice.
Volume: 311
Issue: 1
Pages: H125-36
Publication
First Author: Thompson WR
Year: 1991
Journal: J Biol Chem
Title: A MyoD1-independent muscle-specific enhancer controls the expression of the beta-myosin heavy chain gene in skeletal and cardiac muscle cells.
Volume: 266
Issue: 33
Pages: 22678-88
Publication
First Author: Watkins H
Year: 1992
Journal: N Engl J Med
Title: Characteristics and prognostic implications of myosin missense mutations in familial hypertrophic cardiomyopathy.
Volume: 326
Issue: 17
Pages: 1108-14
Publication
First Author: Knotts S
Year: 1994
Journal: J Biol Chem
Title: In vivo regulation of the mouse beta myosin heavy chain gene.
Volume: 269
Issue: 49
Pages: 31275-82
Publication
First Author: Allegra S
Year: 2005
Journal: Transgenic Res
Title: A 7.1 kbp beta-myosin heavy chain promoter, efficient for green fluorescent protein expression, probably induces lethality when overexpressing a mutated transforming growth factor-beta type II receptor in transgenic mice.
Volume: 14
Issue: 1
Pages: 69-80
GXD Expression    
Probe: MGI:6752653
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716126
Stage: TS26
Assay Id: MGI:6753193
Age: embryonic day 18.5
Image: 3
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6752653
Assay Type: RT-PCR
Annotation Date: 2021-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716126
Stage: TS26
Assay Id: MGI:6753193
Age: embryonic day 18.5
Image: 3
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6435657
Assay Type: RT-PCR
Annotation Date: 2020-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733728
Stage: TS28
Assay Id: MGI:6435741
Age: postnatal day 15
Image: S4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6435657
Assay Type: RT-PCR
Annotation Date: 2020-06-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733728
Stage: TS28
Assay Id: MGI:6435741
Age: postnatal day 15
Image: S4
Detected: true
Specimen Num: 2