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Search results 1 to 100 out of 944 for Myl2

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0.051s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression
Probe: MGI:6433037
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6433831
Age: postnatal day 0
Image: 4b +/+
Note: Comparing immunostaining of the endogenous Myl2 with the tdTomato reporter indicates that there was no significant difference in the endogenous protein expression among the distinct genotypes.
Specimen Label: 4b +/+
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6433037
Assay Type: Immunohistochemistry
Annotation Date: 2020-06-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733127
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:6433831
Age: postnatal day 0
Image: 4b +/-
Note: Comparing immunostaining of the endogenous Myl2 with the tdTomato reporter indicates that there was no significant difference in the endogenous protein expression among the distinct genotypes.
Specimen Label: 4b +/-
Detected: true
Specimen Num: 2
Publication
First Author: Minamisawa S
Year: 1999
Journal: J Biol Chem
Title: A post-transcriptional compensatory pathway in heterozygous ventricular myosin light chain 2-deficient mice results in lack of gene dosage effect during normal cardiac growth or hypertrophy.
Volume: 274
Issue: 15
Pages: 10066-70
Publication
First Author: Garratt AN
Year: 2006
Journal: J Mol Cell Cardiol
Title: "To erb-B or not to erb-B..." Neuregulin-1/ErbB signaling in heart development and function.
Volume: 41
Issue: 2
Pages: 215-8
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication
First Author: Sanbe A
Year: 1999
Journal: J Biol Chem
Title: Abnormal cardiac structure and function in mice expressing nonphosphorylatable cardiac regulatory myosin light chain 2.
Volume: 274
Issue: 30
Pages: 21085-94
Publication
First Author: Chen J
Year: 1998
Journal: J Biol Chem
Title: Selective requirement of myosin light chain 2v in embryonic heart function.
Volume: 273
Issue: 2
Pages: 1252-6
Publication
First Author: Lee MY
Year: 2012
Journal: Stem Cell Res
Title: Derivation of functional ventricular cardiomyocytes using endogenous promoter sequence from murine embryonic stem cells.
Volume: 8
Issue: 1
Pages: 49-57
Publication
First Author: Meikle L
Year: 2005
Journal: Hum Mol Genet
Title: A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.
Volume: 14
Issue: 3
Pages: 429-35
Publication
First Author: Fraccarollo D
Year: 2011
Journal: Circulation
Title: Deletion of cardiomyocyte mineralocorticoid receptor ameliorates adverse remodeling after myocardial infarction.
Volume: 123
Issue: 4
Pages: 400-8
Publication
First Author: Omiya S
Year: 2020
Journal: Circulation
Title: Cytokine mRNA Degradation in Cardiomyocytes Restrains Sterile Inflammation in Pressure-Overloaded Hearts.
Volume: 141
Issue: 8
Pages: 667-677
Publication
First Author: Smart N
Year: 2011
Journal: Nature
Title: De novo cardiomyocytes from within the activated adult heart after injury.
Volume: 474
Issue: 7353
Pages: 640-4
Publication
First Author: Hirota H
Year: 1999
Journal: Cell
Title: Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress.
Volume: 97
Issue: 2
Pages: 189-98
Publication
First Author: Zhao T
Year: 2012
Journal: J Biol Chem
Title: Central role of mitofusin 2 in autophagosome-lysosome fusion in cardiomyocytes.
Volume: 287
Issue: 28
Pages: 23615-25
Publication
First Author: Ma H
Year: 2016
Journal: Gene
Title: ErbB2 is required for cardiomyocyte proliferation in murine neonatal hearts.
Volume: 592
Issue: 2
Pages: 325-30
Publication
First Author: Togi K
Year: 2004
Journal: Mol Cell Biol
Title: Role of Hand1/eHAND in the dorso-ventral patterning and interventricular septum formation in the embryonic heart.
Volume: 24
Issue: 11
Pages: 4627-35
Publication
First Author: Smith RM
Year: 2004
Journal: Cardiovasc Res
Title: Genetic depletion of cardiac myocyte STAT-3 abolishes classical preconditioning.
Volume: 63
Issue: 4
Pages: 611-6
Publication
First Author: Frias MA
Year: 2008
Journal: Cardiovasc Res
Title: The PGE2-Stat3 interaction in doxorubicin-induced myocardial apoptosis.
Volume: 80
Issue: 1
Pages: 69-77
Publication
First Author: Ashrafian H
Year: 2012
Journal: Cell Metab
Title: Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway.
Volume: 15
Issue: 3
Pages: 361-71
Publication
First Author: Shai SY
Year: 2002
Journal: Circ Res
Title: Cardiac myocyte-specific excision of the beta1 integrin gene results in myocardial fibrosis and cardiac failure.
Volume: 90
Issue: 4
Pages: 458-64
Publication
First Author: Lamont K
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Role of melatonin, melatonin receptors and STAT3 in the cardioprotective effect of chronic and moderate consumption of red wine.
Volume: 465
Issue: 4
Pages: 719-24
Publication
First Author: Barwe SP
Year: 2009
Journal: J Mol Cell Cardiol
Title: Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit.
Volume: 47
Issue: 4
Pages: 552-60
Publication
First Author: Yajima T
Year: 2006
Journal: Circulation
Title: Innate defense mechanism against virus infection within the cardiac myocyte requiring gp130-STAT3 signaling.
Volume: 114
Issue: 22
Pages: 2364-73
Publication
First Author: Wei C
Year: 2016
Journal: Mol Cell
Title: RBFox2 Binds Nascent RNA to Globally Regulate Polycomb Complex 2 Targeting in Mammalian Genomes.
Volume: 62
Issue: 6
Pages: 875-889
Publication      
First Author: Wei C
Year: 2015
Journal: Cell Rep
Title: Repression of the Central Splicing Regulator RBFox2 Is Functionally Linked to Pressure Overload-Induced Heart Failure.
Publication
First Author: Suleman N
Year: 2008
Journal: Cardiovasc Res
Title: Dual activation of STAT-3 and Akt is required during the trigger phase of ischaemic preconditioning.
Volume: 79
Issue: 1
Pages: 127-33
Publication
First Author: Li M
Year: 2005
Journal: Circulation
Title: p38 MAP kinase mediates inflammatory cytokine induction in cardiomyocytes and extracellular matrix remodeling in heart.
Volume: 111
Issue: 19
Pages: 2494-502
Publication
First Author: Pashmforoush M
Year: 2004
Journal: Cell
Title: Nkx2-5 pathways and congenital heart disease; loss of ventricular myocyte lineage specification leads to progressive cardiomyopathy and complete heart block.
Volume: 117
Issue: 3
Pages: 373-86
Publication
First Author: Liu W
Year: 2009
Journal: Circ Res
Title: Cardiac-specific deletion of mkk4 reveals its role in pathological hypertrophic remodeling but not in physiological cardiac growth.
Volume: 104
Issue: 7
Pages: 905-14
Publication
First Author: Godoy JC
Year: 2019
Journal: FASEB J
Title: Atorvastatin, but not pravastatin, inhibits cardiac Akt/mTOR signaling and disturbs mitochondrial ultrastructure in cardiac myocytes.
Volume: 33
Issue: 1
Pages: 1209-1225
Publication
First Author: Kecskés M
Year: 2015
Journal: Basic Res Cardiol
Title: The Ca(2+)-activated cation channel TRPM4 is a negative regulator of angiotensin II-induced cardiac hypertrophy.
Volume: 110
Issue: 4
Pages: 43
Publication
First Author: Huang Y
Year: 2004
Journal: FASEB J
Title: Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart.
Volume: 18
Issue: 10
Pages: 1138-40
Publication
First Author: Torrente AG
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Burst pacemaker activity of the sinoatrial node in sodium-calcium exchanger knockout mice.
Volume: 112
Issue: 31
Pages: 9769-74
Publication
First Author: Sheikh F
Year: 2006
Journal: Circulation
Title: alpha-E-catenin inactivation disrupts the cardiomyocyte adherens junction, resulting in cardiomyopathy and susceptibility to wall rupture.
Volume: 114
Issue: 10
Pages: 1046-55
Publication
First Author: Liu Y
Year: 2020
Journal: Physiol Rep
Title: PRKAR1A deficiency impedes hypertrophy and reduces heart size.
Volume: 8
Issue: 6
Pages: e14405
Publication
First Author: Liu W
Year: 2011
Journal: Circulation
Title: Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart.
Volume: 124
Issue: 24
Pages: 2702-15
Publication
First Author: Boltzen U
Year: 2012
Journal: J Mol Cell Cardiol
Title: Alternatively spliced tissue factor and full-length tissue factor protect cardiomyocytes against TNF-α-induced apoptosis.
Volume: 52
Issue: 5
Pages: 1056-65
Publication
First Author: Bai Y
Year: 2013
Journal: Am J Physiol Heart Circ Physiol
Title: Different roles of the cardiac Na+/Ca2+-exchanger in ouabain-induced inotropy, cell signaling, and hypertrophy.
Volume: 304
Issue: 3
Pages: H427-35
Publication
First Author: Chen L
Year: 2010
Journal: J Appl Physiol (1985)
Title: The Na+/Ca2+ exchanger-1 mediates left ventricular dysfunction in mice with chronic intermittent hypoxia.
Volume: 109
Issue: 6
Pages: 1675-85
Publication
First Author: Imahashi K
Year: 2005
Journal: Circ Res
Title: Cardiac-specific ablation of the Na+-Ca2+ exchanger confers protection against ischemia/reperfusion injury.
Volume: 97
Issue: 9
Pages: 916-21
Publication
First Author: Pott C
Year: 2005
Journal: Circ Res
Title: Excitation-contraction coupling in Na+-Ca2+ exchanger knockout mice: reduced transsarcolemmal Ca2+ flux.
Volume: 97
Issue: 12
Pages: 1288-95
Publication
First Author: DiMichele LA
Year: 2006
Journal: Circ Res
Title: Myocyte-restricted focal adhesion kinase deletion attenuates pressure overload-induced hypertrophy.
Volume: 99
Issue: 6
Pages: 636-45
Publication
First Author: Henderson SA
Year: 2004
Journal: Circ Res
Title: Functional adult myocardium in the absence of Na+-Ca2+ exchange: cardiac-specific knockout of NCX1.
Volume: 95
Issue: 6
Pages: 604-11
Publication
First Author: Mayer SC
Year: 2015
Journal: Circ Res
Title: Adrenergic Repression of the Epigenetic Reader MeCP2 Facilitates Cardiac Adaptation in Chronic Heart Failure.
Volume: 117
Issue: 7
Pages: 622-33
Publication
First Author: Pott C
Year: 2007
Journal: Biophys J
Title: Regulation of cardiac L-type Ca2+ current in Na+-Ca2+ exchanger knockout mice: functional coupling of the Ca2+ channel and the Na+-Ca2+ exchanger.
Volume: 92
Issue: 4
Pages: 1431-7
Publication
First Author: García-Rivello H
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle.
Volume: 289
Issue: 3
Pages: H1153-60
Publication
First Author: Jordan MC
Year: 2010
Journal: J Card Fail
Title: Myocardial function with reduced expression of the sodium-calcium exchanger.
Volume: 16
Issue: 9
Pages: 786-96
Publication
First Author: Lacerda L
Year: 2009
Journal: Cardiovasc Res
Title: Ischaemic postconditioning protects against reperfusion injury via the SAFE pathway.
Volume: 84
Issue: 2
Pages: 201-8
Publication
First Author: Liu F
Year: 2015
Journal: Circ Cardiovasc Genet
Title: GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and Function.
Volume: 8
Issue: 2
Pages: 284-93
Publication
First Author: Ljubojević-Holzer S
Year: 2022
Journal: Cardiovasc Res
Title: Loss of autophagy protein ATG5 impairs cardiac capacity in mice and humans through diminishing mitochondrial abundance and disrupting Ca2+ cycling.
Volume: 118
Issue: 6
Pages: 1492-1505
Publication  
First Author: Haley SA
Year: 2008
Journal: BMC Physiol
Title: Forced expression of the cell cycle inhibitor p57Kip2 in cardiomyocytes attenuates ischemia-reperfusion injury in the mouse heart.
Volume: 8
Pages: 4
Publication
First Author: Hu J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: RBFox2-miR-34a-Jph2 axis contributes to cardiac decompensation during heart failure.
Volume: 116
Issue: 13
Pages: 6172-6180
Publication
First Author: Oyabu J
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Autophagy-mediated degradation is necessary for regression of cardiac hypertrophy during ventricular unloading.
Volume: 441
Issue: 4
Pages: 787-92
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication
First Author: Li J
Year: 2017
Journal: Dev Biol
Title: Essential role of Cdc42 in cardiomyocyte proliferation and cell-cell adhesion during heart development.
Volume: 421
Issue: 2
Pages: 271-283
Publication
First Author: Peng X
Year: 2006
Journal: J Clin Invest
Title: Inactivation of focal adhesion kinase in cardiomyocytes promotes eccentric cardiac hypertrophy and fibrosis in mice.
Volume: 116
Issue: 1
Pages: 217-27
Publication
First Author: Amann R
Year: 2014
Journal: Dev Biol
Title: The FgfrL1 receptor is required for development of slow muscle fibers.
Volume: 394
Issue: 2
Pages: 228-41
Publication
First Author: DiMichele LA
Year: 2009
Journal: Circ Res
Title: Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth.
Volume: 104
Issue: 10
Pages: 1201-8
Publication
First Author: Hinrichs S
Year: 2011
Journal: Cardiovasc Res
Title: Controlling cardiomyocyte length: the role of renin and PPAR-{gamma}.
Volume: 89
Issue: 2
Pages: 344-52
Publication
First Author: Mirtschink P
Year: 2015
Journal: Nature
Title: HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease.
Volume: 522
Issue: 7557
Pages: 444-449
Publication
First Author: Liu Y
Year: 2021
Journal: J Biol Chem
Title: Loss of PKA regulatory subunit 1α aggravates cardiomyocyte necrosis and myocardial ischemia/reperfusion injury.
Volume: 297
Issue: 1
Pages: 100850
Publication
First Author: Hikoso S
Year: 2009
Journal: Circ Res
Title: The I{kappa}B kinase {beta}/nuclear factor {kappa}B signaling pathway protects the heart from hemodynamic stress mediated by the regulation of manganese superoxide dismutase expression.
Volume: 105
Issue: 1
Pages: 70-9
Publication
First Author: Zemljic-Harpf AE
Year: 2007
Journal: Mol Cell Biol
Title: Cardiac-myocyte-specific excision of the vinculin gene disrupts cellular junctions, causing sudden death or dilated cardiomyopathy.
Volume: 27
Issue: 21
Pages: 7522-37
Publication
First Author: Crone SA
Year: 2002
Journal: Nat Med
Title: ErbB2 is essential in the prevention of dilated cardiomyopathy.
Volume: 8
Issue: 5
Pages: 459-65
Publication
First Author: Ling H
Year: 2013
Journal: Circ Res
Title: Ca2+/Calmodulin-dependent protein kinase II δ mediates myocardial ischemia/reperfusion injury through nuclear factor-κB.
Volume: 112
Issue: 6
Pages: 935-44
Publication
First Author: Gutstein DE
Year: 2001
Journal: Cell Commun Adhes
Title: Conditional gene targeting of connexin43: exploring the consequences of gap junction remodeling in the heart.
Volume: 8
Issue: 4-6
Pages: 345-8
Publication
First Author: Papanicolaou KN
Year: 2010
Journal: J Mol Cell Cardiol
Title: Preserved heart function and maintained response to cardiac stresses in a genetic model of cardiomyocyte-targeted deficiency of cyclooxygenase-2.
Volume: 49
Issue: 2
Pages: 196-209
Publication
First Author: Andersson KB
Year: 2009
Journal: Cell Calcium
Title: Mice carrying a conditional Serca2(flox) allele for the generation of Ca(2+) handling-deficient mouse models.
Volume: 46
Issue: 3
Pages: 219-25
Publication
First Author: Chen J
Year: 1998
Journal: Development
Title: Ventricular muscle-restricted targeting of the RXRalpha gene reveals a non-cell-autonomous requirement in cardiac chamber morphogenesis.
Volume: 125
Issue: 10
Pages: 1943-9
Publication
First Author: Ozcelik C
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
Volume: 99
Issue: 13
Pages: 8880-5
Publication
First Author: Mühlstedt S
Year: 2016
Journal: J Mol Med (Berl)
Title: Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction.
Volume: 94
Issue: 9
Pages: 1005-14
Publication
First Author: Auer DR
Year: 2014
Journal: Biotechnol Lett
Title: Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse.
Volume: 36
Issue: 6
Pages: 1179-85
Publication
First Author: Hakim ZS
Year: 2009
Journal: J Mol Cell Cardiol
Title: FAK regulates cardiomyocyte survival following ischemia/reperfusion.
Volume: 46
Issue: 2
Pages: 241-8
Publication
First Author: Stieber J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart.
Volume: 100
Issue: 25
Pages: 15235-40
Publication
First Author: Ishikawa TO
Year: 2011
Journal: Mol Imaging Biol
Title: Conditional bicistronic Cre reporter line expressing both firefly luciferase and β-galactosidase.
Volume: 13
Issue: 2
Pages: 284-92
Publication
First Author: Rentschler S
Year: 2011
Journal: J Clin Invest
Title: Notch signaling regulates murine atrioventricular conduction and the formation of accessory pathways.
Volume: 121
Issue: 2
Pages: 525-33
Publication
First Author: Chowdhury SK
Year: 2017
Journal: Circulation
Title: Stress-Activated Kinase Mitogen-Activated Kinase Kinase-7 Governs Epigenetics of Cardiac Repolarization for Arrhythmia Prevention.
Volume: 135
Issue: 7
Pages: 683-699
Publication
First Author: Jakupoglu C
Year: 2005
Journal: Mol Cell Biol
Title: Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development.
Volume: 25
Issue: 5
Pages: 1980-8
Publication
First Author: McCommis KS
Year: 2020
Journal: Nat Metab
Title: Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice.
Volume: 2
Issue: 11
Pages: 1232-1247
Publication
First Author: Hodges WT
Year: 2022
Journal: J Biol Chem
Title: Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice.
Volume: 298
Issue: 2
Pages: 101554
Publication
First Author: Michele DE
Year: 2009
Journal: Circ Res
Title: Dystroglycan matrix receptor function in cardiac myocytes is important for limiting activity-induced myocardial damage.
Volume: 105
Issue: 10
Pages: 984-93
Publication
First Author: Caglayan E
Year: 2008
Journal: Diabetes
Title: Differential roles of cardiomyocyte and macrophage peroxisome proliferator-activated receptor gamma in cardiac fibrosis.
Volume: 57
Issue: 9
Pages: 2470-9
Publication
First Author: Schoenauer R
Year: 2011
Journal: Basic Res Cardiol
Title: EH-myomesin splice isoform is a novel marker for dilated cardiomyopathy.
Volume: 106
Issue: 2
Pages: 233-47
Publication
First Author: Elsherif L
Year: 2008
Journal: Circ Res
Title: Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification.
Volume: 102
Issue: 9
Pages: 1109-17
Publication
First Author: Liang X
Year: 2005
Journal: Mol Cell Biol
Title: PINCH1 plays an essential role in early murine embryonic development but is dispensable in ventricular cardiomyocytes.
Volume: 25
Issue: 8
Pages: 3056-62
Publication
First Author: St Amand TR
Year: 2006
Journal: Dev Biol
Title: Distinct roles of HF-1b/Sp4 in ventricular and neural crest cells lineages affect cardiac conduction system development.
Volume: 291
Issue: 2
Pages: 208-17
Publication
First Author: Vong LH
Year: 2005
Journal: Genesis
Title: Generation of conditional Mef2cloxP/loxP mice for temporal- and tissue-specific analyses.
Volume: 43
Issue: 1
Pages: 43-8
Publication  
First Author: Chambers KT
Year: 2021
Journal: JCI Insight
Title: Myocardial Lipin 1 knockout in mice approximates cardiac effects of human LPIN1 mutations.
Volume: 6
Issue: 9
Publication
First Author: Rentschler S
Year: 2012
Journal: Circulation
Title: Myocardial Notch signaling reprograms cardiomyocytes to a conduction-like phenotype.
Volume: 126
Issue: 9
Pages: 1058-66
Publication
First Author: Conrad M
Year: 2004
Journal: Mol Cell Biol
Title: Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function.
Volume: 24
Issue: 21
Pages: 9414-23
Publication
First Author: Lei L
Year: 2008
Journal: Mol Cell Biol
Title: Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein.
Volume: 28
Issue: 11
Pages: 3790-803