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Search results 1 to 100 out of 213 for Myo15a

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0.038s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Myosin XVa is an unconventional myosin that is critical for the normal growth of mechanosensory stereocilia of inner ear hair cells []. Mutations in the myosin XVa gene are associated with nonsyndromic hearing loss []. Myosin XVa contains a unique N-terminal extension followed by a motor domain, light chain-binding IQ motifs, and a tail consisting of a pair of MyTH4-FERM tandems separated by a SH3 domain, and a PDZ domain.
Publication
First Author: Sellers JR
Year: 2000
Journal: Biochim Biophys Acta
Title: Myosins: a diverse superfamily.
Volume: 1496
Issue: 1
Pages: 3-22
Publication
First Author: Kanzaki S
Year: 2006
Journal: Hear Res
Title: Transgene correction maintains normal cochlear structure and function in 6-month-old Myo15a mutant mice.
Volume: 214
Issue: 1-2
Pages: 37-44
Protein
Organism: Mus musculus/domesticus
Length: 3511  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1784  
Fragment?: true
Publication  
First Author: Libby RT
Year: 2000
Journal: Essays Biochem
Title: The roles of unconventional myosins in hearing and deafness.
Volume: 35
Pages: 159-74
Publication
First Author: Pacentine IV
Year: 2021
Journal: Sci Rep
Title: Cy3-ATP labeling of unfixed, permeabilized mouse hair cells.
Volume: 11
Issue: 1
Pages: 23855
Publication
First Author: Tadenev ALD
Year: 2019
Journal: Curr Biol
Title: GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity.
Volume: 29
Issue: 6
Pages: 921-934.e4
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Belyantseva IA
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Myosin XVa localizes to the tips of inner ear sensory cell stereocilia and is essential for staircase formation of the hair bundle.
Volume: 100
Issue: 24
Pages: 13958-63
Publication
First Author: Probst FJ
Year: 1998
Journal: Science
Title: Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.
Volume: 280
Issue: 5368
Pages: 1444-7
Publication      
First Author: Gagnon LH
Year: 2005
Journal: MGI Direct Data Submission
Title: A new allele of myosin XV (Myo15)
Publication
First Author: Erichsen S
Year: 2001
Journal: Acta Otolaryngol
Title: Cochlear distribution of Na,K-ATPase and corticosteroid receptors in two mouse strains with congenital hearing disorders.
Volume: 121
Issue: 7
Pages: 794-802
Publication  
First Author: Dobrovolskaia-Zavasdkaia N
Year: 1928
Journal: Arch Biol (Liege)
Title: L'irradiation des testicules et l'heredite chez la souris.
Volume: 38
Pages: 457-501
Publication
First Author: Wright ME
Year: 1947
Journal: Heredity
Title: Two sex-linkages in the house mouse, with unusual recombination values.
Volume: 1
Issue: 3
Pages: 349-54
Publication    
First Author: Fang Q
Year: 2015
Journal: Elife
Title: The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing.
Volume: 4
Publication
First Author: Anderson DW
Year: 2000
Journal: Hum Mol Genet
Title: The motor and tail regions of myosin XV are critical for normal structure and function of auditory and vestibular hair cells.
Volume: 9
Issue: 12
Pages: 1729-38
Publication
First Author: Stepanyan R
Year: 2009
Journal: J Neurosci
Title: Fast adaptation and Ca2+ sensitivity of the mechanotransducer require myosin-XVa in inner but not outer cochlear hair cells.
Volume: 29
Issue: 13
Pages: 4023-34
Publication
First Author: Lee DJ
Year: 2003
Journal: J Neurocytol
Title: Effects of congenital deafness in the cochlear nuclei of Shaker-2 mice: an ultrastructural analysis of synapse morphology in the endbulbs of Held.
Volume: 32
Issue: 3
Pages: 229-43
Publication
First Author: Webster DB
Year: 1986
Journal: Acta Otolaryngol
Title: Incomplete maturation of brainstem auditory nuclei in genetically induced early postnatal cochlear degeneration.
Volume: 101
Issue: 5-6
Pages: 429-38
Publication
First Author: Anniko M
Year: 1982
Journal: Hear Res
Title: Specific pathology of the stria vascularis in postnatal progressive genetic inner ear disorder.
Volume: 6
Issue: 3
Pages: 247-58
Publication
First Author: Clark FH
Year: 1935
Journal: Proc Natl Acad Sci U S A
Title: Linkage Relations of Zavadskaia Shaker in the House Mouse (Mus musculus).
Volume: 21
Issue: 5
Pages: 247-51
Publication
First Author: Sobin A
Year: 1982
Journal: Arch Otorhinolaryngol
Title: Rods of actin filaments in type I hair cells of the Shaker-2 mouse.
Volume: 236
Issue: 1
Pages: 1-6
Publication
First Author: Hadi S
Year: 2020
Journal: J Assoc Res Otolaryngol
Title: Myosin-XVa Controls Both Staircase Architecture and Diameter Gradation of Stereocilia Rows in the Auditory Hair Cell Bundles.
Volume: 21
Issue: 2
Pages: 121-135
Publication      
First Author: Prince L
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for typhoon
Publication      
First Author: Gagnon L
Year: 2001
Journal: MGI Direct Data Submission
Title: Second remutation to shaker 2 at The Jackson Laboratory
Publication      
First Author: Purrington T
Year: 2014
Journal: MGI Direct Data Submission
Title: Direct data submission for Mutagenetix entry for parker
Publication  
First Author: Kiernan AE
Year: 2000
Journal: Adv Otorhinolaryngol
Title: Mouse homologues for human deafness.
Volume: 56
Pages: 233-43
Publication
First Author: Falconer DS
Year: 1947
Journal: Heredity
Title: Linkage of rex with shaker-2 in the house mouse.
Volume: 1
Issue: 1
Pages: 133-5
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: brain
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: spleen
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: lung
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: liver
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: kidney
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2678358
Age: postnatal adult
Specimen Label: testis
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2678359
Age: embryonic day 7.0
Specimen Label: 7-day
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2678359
Age: embryonic day 11.0
Specimen Label: 11-day
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2678359
Age: embryonic day 15.0
Specimen Label: 15-day
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1303105
Assay Type: Northern blot
Annotation Date: 2003-11-05
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2678359
Age: embryonic day 17.0
Specimen Label: 17-day
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:2678360
Assay Type: RT-PCR
Annotation Date: 2003-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185827
Stage: TS27
Assay Id: MGI:2678362
Age: postnatal newborn
Specimen Label: head
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2678360
Assay Type: RT-PCR
Annotation Date: 2003-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:2678362
Age: postnatal newborn
Specimen Label: head
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:2678360
Assay Type: RT-PCR
Annotation Date: 2003-11-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:2576527
Stage: TS27
Assay Id: MGI:2678362
Age: postnatal newborn
Specimen Label: tissues
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3046318
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3046321
Age: postnatal adult
Specimen Label: 1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3046318
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3046321
Age: postnatal adult
Specimen Label: 2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3046318
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3046321
Age: postnatal adult
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3046318
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3046321
Age: postnatal adult
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3046317
Assay Type: RT-PCR
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:3046322
Age: postnatal adult
Specimen Label: 3
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3046317
Assay Type: RT-PCR
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3046322
Age: postnatal adult
Specimen Label: 4
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3046317
Assay Type: RT-PCR
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619426
Stage: TS26
Assay Id: MGI:3046322
Age: embryonic day 18.0
Specimen Label: 5
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3046317
Assay Type: RT-PCR
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619426
Stage: TS26
Assay Id: MGI:3046322
Age: embryonic day 18.0
Specimen Label: 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3046317
Assay Type: RT-PCR
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619426
Stage: TS26
Assay Id: MGI:3046322
Age: embryonic day 18.0
Specimen Label: 7
Detected: true
Specimen Num: 7
GXD Expression        
Probe: MGI:3849187
Assay Type: Northern blot
Annotation Date: 2009-06-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:3849196
Age: postnatal adult
Specimen Label: None
Specimen Num: 1
GXD Expression        
Probe: MGI:3849188
Assay Type: Northern blot
Annotation Date: 2009-06-30
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:3849197
Age: postnatal adult
Specimen Label: None
Specimen Num: 1
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4867259
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4867259
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4867259
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4867259
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867259
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867259
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4867239
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867259
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:3849187
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3849199
Age: embryonic day 18.5
Note: Expression was detected in the upper epithelial layer of the macula sacculi.
Specimen Label: 7A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3849191
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729226
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3849200
Age: embryonic day 18.5
Note: Expression was detected in the upper epithelial layer of the macula sacculi.
Specimen Label: 7C
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3849187
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3849199
Age: embryonic day 15.5
Specimen Label: Not shown
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3849187
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3849199
Age: postnatal day 1
Specimen Label: Not shown
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:3849191
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:3849200
Age: embryonic day 15.5
Specimen Label: Not shown
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3849191
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3849200
Age: postnatal day 1
Specimen Label: Not shown
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:7437814
Assay Type: RNA in situ
Annotation Date: 2023-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7437896
Age: embryonic day 15.5
Image: 3b
Specimen Label: 3b
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7437814
Assay Type: RNA in situ
Annotation Date: 2023-02-23
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7437896
Age: embryonic day 15.5
Image: 3b
Specimen Label: 3b
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5474568
Assay Type: RNA in situ
Annotation Date: 2013-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728627
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5474569
Age: postnatal day 1
Image: 1C Vestibule
Note: Expression is in hair cells.
Specimen Label: 1C Vestibule
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3849187
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3849199
Age: embryonic day 18.5
Note: Expression was detected in the cochlear neurosensory hair cells.
Specimen Label: 7A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3849191
Assay Type: RNA in situ
Annotation Date: 2009-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:3849200
Age: embryonic day 18.5
Note: Expression was detected in the cochlear neurosensory hair cells.
Specimen Label: 7C
Detected: true
Specimen Num: 1