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Search results 1 to 91 out of 91 for Myo3a

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Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
53904 | MYO3A
Type: gene
Organism: human
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Gene
100495574 | myo3a
Type: gene
Organism: frog, western clawed
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Gene
498806 | Myo3a
Type: gene
Organism: rat
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Gene
450359 | MYO3A
Type: gene
Organism: chimpanzee
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Gene
487106 | MYO3A
Type: gene
Organism: dog, domestic
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Gene
535824 | MYO3A
Type: gene
Organism: cattle
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Gene
420494 | MYO3A
Type: gene
Organism: chicken
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Gene
402814 | myo3a
Type: gene
Organism: zebrafish
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Gene
707165 | MYO3A
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2183924 | Myo3a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30123247 | J:278835
 
First Author: Li P
Year: 2018
Journal: Neural Plast
Title: Knock-In Mice with Myo3a Y137C Mutation Displayed Progressive Hearing Loss and Hair Cell Degeneration in the Inner Ear.
Volume: 2018
Pages: 4372913
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Publication
12672820 | J:116303
First Author: Komaba S
Year: 2003
Journal: J Biol Chem
Title: Determination of human myosin III as a motor protein having a protein kinase activity.
Volume: 278
Issue: 24
Pages: 21352-60
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Publication
26926603 | J:236347
 
First Author: Ebrahim S
Year: 2016
Journal: Nat Commun
Title: Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.
Volume: 7
Pages: 10833
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Publication
26754646 | J:230827
First Author: Lelli A
Year: 2016
Journal: J Cell Biol
Title: Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.
Volume: 212
Issue: 2
Pages: 231-44
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Publication
22264607 | J:182310
First Author: Merritt RC
Year: 2012
Journal: Curr Biol
Title: Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.
Volume: 22
Issue: 4
Pages: 320-5
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Publication
19332056 | J:151015
First Author: Katti C
Year: 2009
Journal: Exp Eye Res
Title: Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.
Volume: 89
Issue: 2
Pages: 224-37
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Protein Coding Gene
MGP_CAROLIEiJ_G0023221 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025368 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025336 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025363 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025123 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2183924 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0025806 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024587 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025102 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025234 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025228 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0025864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024336 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024657 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024677 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024136 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12032315 | J:76870
First Author: Walsh T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30.
Volume: 99
Issue: 11
Pages: 7518-23
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Publication
21165622 | J:166812
First Author: Walsh VL
Year: 2011
Journal: Mamm Genome
Title: A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA.
Volume: 22
Issue: 3-4
Pages: 170-7
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4867257
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4867257
Age: embryonic day 18.0
Specimen Label: E18
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4867257
Age: postnatal day 0
Specimen Label: P0
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4867257
Age: postnatal day 2
Specimen Label: P2
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867257
Age: postnatal day 4
Specimen Label: P4
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867257
Age: postnatal day 6
Specimen Label: P6
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867257
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692519
Age: postnatal adult
Image: JAX_1262027
Note: kidney
Specimen Label: JAX_1262027
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6692519
Age: postnatal adult
Image: JAX_1262025
Specimen Label: JAX_1262025
Detected: false
Specimen Num: 1
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Publication
21895655 | J:177890
First Author: Dalal JS
Year: 2011
Journal: J Neurochem
Title: Mouse class III myosins: kinase activity and phosphorylation sites.
Volume: 119
Issue: 4
Pages: 772-84
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Publication
19339464 | J:151359
First Author: Lelli A
Year: 2009
Journal: J Neurophysiol
Title: Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.
Volume: 101
Issue: 6
Pages: 2961-73
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Allele
Myo3a<em1Jgao> | MGI:6363571
Name: myosin IIIA; endonuclease-mediated mutation 1, Jiangang Gao
Allele Type: Endonuclease-mediated
Attribute String: Hypomorph
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DO Term
DOID:0070607 | autosomal dominant nonsyndromic deafness 90
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Allele
Myo3a<tm1.1Mckg> | MGI:4849286
Name: myosin IIIA; targeted mutation 1.1, Mary-Claire King
Allele Type: Targeted
Attribute String: Humanized sequence
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Genotype
Genotype
Symbol: Myo3a/Myo3a
Background: C57BL/6-Myo3a
Zygosity: hm
Has Mutant Allele: true
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DO Term
DOID:0110489 | autosomal recessive nonsyndromic deafness 30
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Publication
10936054 | -
First Author: Dosé AC
Year: 2000
Journal: Genomics
Title: Cloning and chromosomal localization of a human class III myosin.
Volume: 67
Issue: 3
Pages: 333-42
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Publication
10722876 | -
First Author: Bähler M
Year: 2000
Journal: Biochim Biophys Acta
Title: Are class III and class IX myosins motorized signalling molecules?
Volume: 1496
Issue: 1
Pages: 52-9
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Protein Domain
IPR036083 | MYSc_Myo3
Type: Domain
Description: Myosin III is an actin-based motor protein with protein kinase activity []. It has been shown to play a role in the vision process and in hearing in mammals [, ]. There are two paralogues of Myo3 in vertebrates, Myo3a and Myo3b, both known to be expressed in vertebrate retina and cochlea. They are thought to be crucial for photoreceptor and stereocilia ultrastructure maintenance []. Class III myosins are characterized by the presence of an N-terminal protein kinase domain before their motor head domain. They are unconventional myosins that do not form dimers []. The catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases.
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Publication
35962067 | J:345076
First Author: Ballesteros A
Year: 2022
Journal: Sci Rep
Title: Selective binding and transport of protocadherin 15 isoforms by stereocilia unconventional myosins in a heterologous expression system.
Volume: 12
Issue: 1
Pages: 13764
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Publication
12471888 | -
 
First Author: Kalhammer G
Year: 2000
Journal: Essays Biochem
Title: Unconventional myosins.
Volume: 35
Pages: 33-42
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Protein
Q8K3H5
Organism: Mus musculus/domesticus
Length: 1613  
Fragment?: false
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Protein
Q1EG27
Organism: Mus musculus/domesticus
Length: 1305  
Fragment?: false
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Protein
F6QNG5
Organism: Mus musculus/domesticus
Length: 1621  
Fragment?: false
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Protein
F8VQ79
Organism: Mus musculus/domesticus
Length: 1333  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom