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Search results 1 to 78 out of 78 for Myo3a

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication  
First Author: Li P
Year: 2018
Journal: Neural Plast
Title: Knock-In Mice with Myo3a Y137C Mutation Displayed Progressive Hearing Loss and Hair Cell Degeneration in the Inner Ear.
Volume: 2018
Pages: 4372913
Publication
First Author: Komaba S
Year: 2003
Journal: J Biol Chem
Title: Determination of human myosin III as a motor protein having a protein kinase activity.
Volume: 278
Issue: 24
Pages: 21352-60
Publication  
First Author: Ebrahim S
Year: 2016
Journal: Nat Commun
Title: Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like.
Volume: 7
Pages: 10833
Publication
First Author: Lelli A
Year: 2016
Journal: J Cell Biol
Title: Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth.
Volume: 212
Issue: 2
Pages: 231-44
Publication
First Author: Merritt RC
Year: 2012
Journal: Curr Biol
Title: Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions.
Volume: 22
Issue: 4
Pages: 320-5
Publication
First Author: Katti C
Year: 2009
Journal: Exp Eye Res
Title: Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.
Volume: 89
Issue: 2
Pages: 224-37
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Walsh T
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: From flies' eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30.
Volume: 99
Issue: 11
Pages: 7518-23
Publication
First Author: Walsh VL
Year: 2011
Journal: Mamm Genome
Title: A mouse model for human hearing loss DFNB30 due to loss of function of myosin IIIA.
Volume: 22
Issue: 3-4
Pages: 170-7
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759725
Stage: TS25
Assay Id: MGI:4867257
Age: embryonic day 17.0
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759726
Stage: TS26
Assay Id: MGI:4867257
Age: embryonic day 18.0
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4867257
Age: postnatal day 0
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759727
Stage: TS27
Assay Id: MGI:4867257
Age: postnatal day 2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867257
Age: postnatal day 4
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867257
Age: postnatal day 6
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:4867241
Assay Type: RT-PCR
Annotation Date: 2011-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1759728
Stage: TS28
Assay Id: MGI:4867257
Age: postnatal day 8
Detected: true
Specimen Num: 7
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1737328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692519
Age: postnatal adult
Image: JAX_1262027
Note: kidney
Detected: true
Specimen Num: 2
GXD Expression      
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:6692519
Age: postnatal adult
Image: JAX_1262025
Detected: false
Specimen Num: 1
Publication
First Author: Dalal JS
Year: 2011
Journal: J Neurochem
Title: Mouse class III myosins: kinase activity and phosphorylation sites.
Volume: 119
Issue: 4
Pages: 772-84
Publication
First Author: Lelli A
Year: 2009
Journal: J Neurophysiol
Title: Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea.
Volume: 101
Issue: 6
Pages: 2961-73
Publication      
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: myosin IIIA; endonuclease-mediated mutation 1, Jiangang Gao
Allele Type: Endonuclease-mediated
Attribute String: Hypomorph
Publication categories: ProxyCollection
Allele
Name: myosin IIIA; targeted mutation 1.1, Mary-Claire King
Allele Type: Targeted
Attribute String: Humanized sequence
Publication categories: ProxyCollection
Genotype
Symbol: Myo3a/Myo3a
Background: C57BL/6-Myo3a
Zygosity: hm
Has Mutant Allele: true
DO Term
Publication
First Author: Dosé AC
Year: 2000
Journal: Genomics
Title: Cloning and chromosomal localization of a human class III myosin.
Volume: 67
Issue: 3
Pages: 333-42
Publication
First Author: Bähler M
Year: 2000
Journal: Biochim Biophys Acta
Title: Are class III and class IX myosins motorized signalling molecules?
Volume: 1496
Issue: 1
Pages: 52-9
Protein Domain
Type: Domain
Description: Myosin III is an actin-based motor protein with protein kinase activity []. It has been shown to play a role in the vision process and in hearing in mammals [, ]. There are two paralogues of Myo3 in vertebrates, Myo3a and Myo3b, both known to be expressed in vertebrate retina and cochlea. They are thought to be crucial for photoreceptor and stereocilia ultrastructure maintenance []. Class III myosins are characterized by the presence of an N-terminal protein kinase domain before their motor head domain. They are unconventional myosins that do not form dimers []. The catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases.
Publication  
First Author: Kalhammer G
Year: 2000
Journal: Essays Biochem
Title: Unconventional myosins.
Volume: 35
Pages: 33-42
Protein
Organism: Mus musculus
Length: 1613  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1305  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1333  
Fragment?: false
Protein
Organism: Mus musculus
Length: 1621  
Fragment?: false