|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 77 out of 77 for Naaladl1

0.041s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
10004 | NAALADL1
Type: gene
Organism: human
•
•
•
•
•
Gene
100487953 | naaladl1
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
83568 | Naaladl1
Type: gene
Organism: rat
•
•
•
•
•
Gene
483751 | NAALADL1
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
451309 | NAALADL1
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
506692 | NAALADL1
Type: gene
Organism: cattle
•
•
•
•
•
Gene
100000223 | naaladl1
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
717018 | NAALADL1
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:2685810 | Naaladl1
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Gene
100487005 | LOC100487005
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Publication
12838346 | J:84749
First Author: Puente XS
Year: 2003
Journal: Nat Rev Genet
Title: Human and mouse proteases: a comparative genomic approach.
Volume: 4
Issue: 7
Pages: 544-58
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0022594 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0024748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0024714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0024687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0024714 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0024482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_2685810 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0025160 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0023954 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0024454 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0024581 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0024547 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0024667 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0024576 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0025208 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0023700 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0024016 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0014088 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0023505 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Gene
100037180 | LOC100487005.L
Type: gene
Organism: frog, African clawed
•
•
•
•
•
Publication
- | J:147112
     
First Author: Taconic
Year: 2006
Journal: MGI Direct Data Submission
Title: Information obtained from Taconic website.
•
•
•
•
•
Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
•
•
•
•
•
Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
•
•
•
•
•
Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
•
•
•
•
•
Publication
- | J:73796
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
•
•
•
•
•
Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
•
•
•
•
•
Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
UniProt Feature
UniProt Feature
Begin: 1
Description: Aminopeptidase NAALADL1
Type: chain
End: 745
•
•
•
•
•
Protein
Q7M758
Organism: Mus musculus/domesticus
Length: 745  
Fragment?: false
•
•
•
•
•
Allele
Naaladl1<em1(cre)Smoc> | MGI:7291222
Name: N-acetylated alpha-linked acidic dipeptidase-like 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Recombinase
•
•
•
•
•
Allele
Naaladl1<em2Smoc> | MGI:7291223
Name: N-acetylated alpha-linked acidic dipeptidase-like 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
•
•
•
•
•
Protein
E9PV01
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
•
•
•
•
•
Protein
A0A0G2JED7
Organism: Mus musculus/domesticus
Length: 123  
Fragment?: true
•
•
•
•
•
Publication
16467855 | -
First Author: Mesters JR
Year: 2006
Journal: EMBO J
Title: Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer.
Volume: 25
Issue: 6
Pages: 1375-84
•
•
•
•
•
Publication
18234225 | -
First Author: Barinka C
Year: 2008
Journal: J Mol Biol
Title: Structural basis of interactions between human glutamate carboxypeptidase II and its substrate analogs.
Volume: 376
Issue: 5
Pages: 1438-50
•
•
•
•
•
Publication
10085079 | -
First Author: Pangalos MN
Year: 1999
Journal: J Biol Chem
Title: Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity.
Volume: 274
Issue: 13
Pages: 8470-83
•
•
•
•
•
Publication
25752612 | -
First Author: Tykvart J
Year: 2015
Journal: J Biol Chem
Title: Structural and biochemical characterization of a novel aminopeptidase from human intestine.
Volume: 290
Issue: 18
Pages: 11321-36
•
•
•
•
•
Protein Domain
IPR039373 | Peptidase_M28B
Type: Family
Description: This entry includes glutamate carboxypeptidase 2 (FOLH1) and its homologues from peptidase family M28 subfamily B. Not all members of this subfamily are peptidases, and non-peptidase homologues include transferrin receptor proteins.FOLH1 is a zinc-dependent carboxypeptidase that also acts as a folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase). It has a preference for tri-alpha-glutamate peptides []. It is required for the uptake of folate in the intestine, and in the brain modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), releasing glutamate. Two zinc ions are bound per molecule []. NAALADL1 and NAALAD2 are also included in this entry. NAALAD2 has both N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) and dipeptidyl-peptidase IV type activity []. The structure of NAALADase has been solved []. The transferrin receptor (TfR) assists iron uptake into vertebrate cells through a cycle of endo- and exocytosis of the iron transport protein transferrin (Tf). TfR binds iron-loaded (diferric) Tf at the cell surface and carries it to the endosome, where the iron dissociates from Tf. The apo-Tf remains bound to TfR until it reaches the cell surface, where apo-Tf is replaced by diferric Tf from the serum to begin the cycle again. Human TfR is a homodimeric type II transmembrane protein. The crystal structure of a TfR monomer reveals a 3-domain structure: a protease-like domain that closely resembles carboxy- and amino-peptidases; an apical domain consisting of a β-sandwich; and a helical dimerisation domain. The dimerisation domain consists of a 4-helical bundle that makes contact with each of the three domains in the dimer partner [].
•
•
•
•
•
Protein
A0A0N4SUJ3
Organism: Mus musculus/domesticus
Length: 795  
Fragment?: false
•
•
•
•
•
Protein
O35409
Organism: Mus musculus/domesticus
Length: 752  
Fragment?: false
•
•
•
•
•
Protein
Q9JKX3
Organism: Mus musculus/domesticus
Length: 798  
Fragment?: false
•
•
•
•
•
Protein
Q9CZR2
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: false
•
•
•
•
•
Protein
Q32MS9
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: false
•
•
•
•
•
Protein
Q0VDM6
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
•
•
•
•
•
Protein
Q8JZS3
Organism: Mus musculus/domesticus
Length: 107  
Fragment?: true
•
•
•
•
•
Protein
Q3TTB7
Organism: Mus musculus/domesticus
Length: 778  
Fragment?: false
•
•
•
•
•
Protein
Q3UZV6
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: false
•
•
•
•
•
Protein
G3UWC2
Organism: Mus musculus/domesticus
Length: 778  
Fragment?: false
•
•
•
•
•
Protein
Q8C872
Organism: Mus musculus/domesticus
Length: 515  
Fragment?: false
•
•
•
•
•
Publication
10531064 | -
First Author: Lawrence CM
Year: 1999
Journal: Science
Title: Crystal structure of the ectodomain of human transferrin receptor.
Volume: 286
Issue: 5440
Pages: 779-82
•
•
•
•
•
Protein
Q62351
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: false
•
•
•
•
•
Protein
Q542D9
Organism: Mus musculus/domesticus
Length: 763  
Fragment?: false
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom