Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Condensin complexes are involved in the restructuring and maintenance of chromatin. Eukaryotes possess two condensins: condensin I and condensin II. Each complex is composed of structural maintenance of chromosomes protein SMC2 and SMC4, with three additional non-SMC condensin-associated proteins (Ncaps) unique to each condensin (condensin I - Ncaph, Ncapd2, and Ncapg; condensin II - Ncaph2, Ncapd3, and Ncapg2) [, ].This entry includes condensin-2 subunit 2 (Ncaph2) and Kle-2 from C. elegans. Ncaph2 may play a role in lineage-specific role in T-cell development []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Gosling KM |
Year: |
2008 |
Journal: |
Immunology |
Title: |
Defective T-cell function leading to reduced antibody production in a kleisin-beta mutant mouse. |
Volume: |
125 |
Issue: |
2 |
Pages: |
208-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Theodoratos A |
Year: |
2012 |
Journal: |
FEBS J |
Title: |
Splice variants of the condensin II gene Ncaph2 include alternative reading frame translations of exon 1. |
Volume: |
279 |
Issue: |
8 |
Pages: |
1422-32 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
320
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
607
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
576
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirano T |
Year: |
2012 |
Journal: |
Genes Dev |
Title: |
Condensins: universal organizers of chromosomes with diverse functions. |
Volume: |
26 |
Issue: |
15 |
Pages: |
1659-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wood AJ |
Year: |
2010 |
Journal: |
Nat Rev Genet |
Title: |
Condensin and cohesin complexity: the expanding repertoire of functions. |
Volume: |
11 |
Issue: |
6 |
Pages: |
391-404 |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin CA |
Year: |
2016 |
Journal: |
Genes Dev |
Title: |
Mutations in genes encoding condensin complex proteins cause microcephaly through decatenation failure at mitosis. |
Volume: |
30 |
Issue: |
19 |
Pages: |
2158-2172 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Gosling KM |
Year: |
2007 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A mutation in a chromosome condensin II subunit, kleisin beta, specifically disrupts T cell development. |
Volume: |
104 |
Issue: |
30 |
Pages: |
12445-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Houlard M |
Year: |
2021 |
Journal: |
Elife |
Title: |
MCPH1 inhibits Condensin II during interphase by regulating its SMC2-Kleisin interface. |
Volume: |
10 |
|
|
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:1415826 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603923 |
Pattern: |
Ubiquitous |
Stage: |
TS23 |
Assay Id: |
MGI:4826614 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_006527_18 |
|
Specimen Label: |
euxassay_006527_18 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2760523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2769723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2851823 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2762123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2852723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2845723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2874723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1832123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:2854023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5148 |
|
Specimen Label: |
GUDMAP:5148 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2760523 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2769723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2851823 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2762123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2850023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2852723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2845723 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1795023 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1869223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1832123 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797223 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5000616 |
Assay Type: |
RNA in situ |
Annotation Date: |
2014-02-07 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:2853323 |
|
Stage: |
TS23 |
Assay Id: |
MGI:5541176 |
Age: |
embryonic day 15.5 |
Image: |
GUDMAP:5149 |
|
Specimen Label: |
GUDMAP:5149 |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Macdonald L |
Year: |
2022 |
Journal: |
Elife |
Title: |
Rapid and specific degradation of endogenous proteins in mouse models using auxin-inducible degrons. |
Volume: |
11 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Houlard M |
Year: |
2015 |
Journal: |
Nat Cell Biol |
Title: |
Condensin confers the longitudinal rigidity of chromosomes. |
Volume: |
17 |
Issue: |
6 |
Pages: |
771-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Woodward J |
Year: |
2016 |
Journal: |
Genes Dev |
Title: |
Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability. |
Volume: |
30 |
Issue: |
19 |
Pages: |
2173-2186 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rawlings JS |
Year: |
2011 |
Journal: |
EMBO J |
Title: |
Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence. |
Volume: |
30 |
Issue: |
2 |
Pages: |
263-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
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