Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Nuclear receptor coactivator 1 (NCOA1, also known as SRC-1) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors []. These receptors can function as molecular switches [].NCOA1 directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion []. It is involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs) []. It is also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors [, , ]. It plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors []. It can be regulated by sumoylation and ubiquitination []. |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is moderate staining in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
There is weak staining in the postmitotic neurons in the cortical plate of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271220 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271222 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is moderate staining in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271224 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
There is weak staining in the postmitotic neurons in the intermediate zone of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754320 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754322 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754324 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Ncoa1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH. |
Specimen Label: |
Ncoa1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691319 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 11.5 |
Image: |
Ncoa1 - E11.5 |
Note: |
There is weak staining in the ventricular zone of the cerebral cortex and the ganglionic eminences. |
Specimen Label: |
Ncoa1 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271820 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the mantle zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271822 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the mantle zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271824 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones. |
Specimen Label: |
Ncoa1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690819 |
Pattern: |
Non-Uniform |
Stage: |
TS19 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 11.5 |
Image: |
Ncoa1 - E11.5 |
Note: |
There is weak staining in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT. |
Specimen Label: |
Ncoa1 - E11.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753920 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753922 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753924 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
There is moderate staining in the ventricular zone of the DMH and VMH nuclei and weak staining in the PH. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH and ARH nuclei, the AVH and the DAH. |
Specimen Label: |
Ncoa1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1691119 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 11.5 |
Image: |
Ncoa1 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences. |
Specimen Label: |
Ncoa1 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754720 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754722 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is moderate staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754724 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
There is weak staining in the ventricular zone of the cerebral cortex. |
Specimen Label: |
Ncoa1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271020 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the ventricular zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271022 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the ventricular zone of the premam, mam and supramam zones and the TT. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3271024 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
There is weak staining in the ventricular zone of the premam and mam zones. Staining is either absent or ubiquitous in the ventricular zone of the supramam zone. |
Specimen Label: |
Ncoa1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266520 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266522 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the ventricular and mantle zones of the ganglionic eminences. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:3266524 |
Pattern: |
Non-Uniform |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
There is moderate staining in the mantle zone of the ganglionic eminences. Staining is either absent or ubiquitous in the ventricular zone of the ganglionic eminences. |
Specimen Label: |
Ncoa1 - E16.5 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1690619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 11.5 |
Image: |
Ncoa1 - E11.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus, prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT. |
Specimen Label: |
Ncoa1 - E11.5 |
|
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754120 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 12.5 |
Image: |
Ncoa1 - E12.5 |
Note: |
There is weak staining in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Ncoa1 - E12.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Weak |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754122 |
Pattern: |
Not Specified |
Stage: |
TS22 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 14.5 |
Image: |
Ncoa1 - E14.5 |
Note: |
There is weak staining in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Ncoa1 - E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4442691 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-05-13 |
Strength: |
Ambiguous |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754124 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:4450762 |
Age: |
embryonic day 16.5 |
Image: |
Ncoa1 - E16.5 |
Note: |
Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus. |
Specimen Label: |
Ncoa1 - E16.5 |
|
Specimen Num: |
4 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
922
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1447
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
430
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
99
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
54
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
154
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
55
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Litterst CM |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1. |
Volume: |
277 |
Issue: |
39 |
Pages: |
36052-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kalkhoven E |
Year: |
1998 |
Journal: |
EMBO J |
Title: |
Isoforms of steroid receptor co-activator 1 differ in their ability to potentiate transcription by the oestrogen receptor. |
Volume: |
17 |
Issue: |
1 |
Pages: |
232-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Leo C |
Year: |
2000 |
Journal: |
Gene |
Title: |
The SRC family of nuclear receptor coactivators. |
Volume: |
245 |
Issue: |
1 |
Pages: |
1-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Litterst CM |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain. |
Volume: |
278 |
Issue: |
46 |
Pages: |
45340-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Giraud S |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Functional interaction of STAT3 transcription factor with the coactivator NcoA/SRC1a. |
Volume: |
277 |
Issue: |
10 |
Pages: |
8004-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Z |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. |
Volume: |
96 |
Issue: |
17 |
Pages: |
9485-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chauchereau A |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Sumoylation of the progesterone receptor and of the steroid receptor coactivator SRC-1. |
Volume: |
278 |
Issue: |
14 |
Pages: |
12335-43 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6190848 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Ncoa1 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6190848 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Ncoa1 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190848 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Ncoa1 |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:6190848 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Ncoa1 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6190848 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Ncoa1 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190848 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Ncoa1 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6178803 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6190848 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Ncoa1 |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Qin L |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis. |
Volume: |
74 |
Issue: |
13 |
Pages: |
3477-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen X |
Year: |
2010 |
Journal: |
Mol Endocrinol |
Title: |
The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival. |
Volume: |
24 |
Issue: |
10 |
Pages: |
1917-34 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Yuan Y |
Year: |
2007 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Loss-of-function deletion of the steroid receptor coactivator-1 gene in mice reduces estrogen effect on the vascular injury response. |
Volume: |
27 |
Issue: |
7 |
Pages: |
1521-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Monks DA |
Year: |
2003 |
Journal: |
Neuroendocrinology |
Title: |
Steroid receptor coactivator-1 is not required for androgen-mediated sexual differentiation of spinal motoneurons. |
Volume: |
78 |
Issue: |
1 |
Pages: |
45-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Watters RJ |
Year: |
2017 |
Journal: |
Mol Cell Endocrinol |
Title: |
Steroid receptor coactivator-1 can regulate osteoblastogenesis independently of estrogen. |
Volume: |
448 |
|
Pages: |
21-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
van Bergen J |
Year: |
2009 |
Journal: |
J Immunol |
Title: |
Cutting edge: killer Ig-like receptors mediate "missing self" recognition in vivo. |
Volume: |
182 |
Issue: |
5 |
Pages: |
2569-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Walsh CA |
Year: |
2014 |
Journal: |
Cancer Res |
Title: |
Global gene repression by the steroid receptor coactivator SRC-1 promotes oncogenesis. |
Volume: |
74 |
Issue: |
9 |
Pages: |
2533-44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mödder UI |
Year: |
2004 |
Journal: |
Endocrinology |
Title: |
Effects of loss of steroid receptor coactivator-1 on the skeletal response to estrogen in mice. |
Volume: |
145 |
Issue: |
2 |
Pages: |
913-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weiss RE |
Year: |
1999 |
Journal: |
EMBO J |
Title: |
Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone. |
Volume: |
18 |
Issue: |
7 |
Pages: |
1900-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tien JC |
Year: |
2009 |
Journal: |
Int J Biol Sci |
Title: |
The role of SRC-1 in murine prostate cancinogenesis is nonessential due to a possible compensation of SRC-3/AIB1 overexpression. |
Volume: |
5 |
Issue: |
3 |
Pages: |
256-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu L |
Year: |
2013 |
Journal: |
Endocrinology |
Title: |
Steroid receptor coactivator-1 mediates estrogenic actions to prevent body weight gain in female mice. |
Volume: |
154 |
Issue: |
1 |
Pages: |
150-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hinton AO Jr |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
SRC-1 Regulates Blood Pressure and Aortic Stiffness in Female Mice. |
Volume: |
11 |
Issue: |
12 |
Pages: |
e0168644 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takeuchi Y |
Year: |
2002 |
Journal: |
Endocrinology |
Title: |
Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo. |
Volume: |
143 |
Issue: |
4 |
Pages: |
1346-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
McCartan D |
Year: |
2012 |
Journal: |
Cancer Res |
Title: |
Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer. |
Volume: |
72 |
Issue: |
1 |
Pages: |
220-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baudino L |
Year: |
2008 |
Journal: |
J Immunol |
Title: |
Dissection of genetic mechanisms governing the expression of serum retroviral gp70 implicated in murine lupus nephritis. |
Volume: |
181 |
Issue: |
4 |
Pages: |
2846-54 |
|
•
•
•
•
•
|