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Search results 1 to 100 out of 498 for Ncoa2

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Domain
Type: Family
Description: Nuclear receptor coactivator 2 (NCOA2, also known as Tif2) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors []. These receptors can function as molecular switches [].NCOA2 is a transcriptional coactivator for steroid receptors and nuclear receptors. It functions as a coactivator of the steroid binding domain (AF-2) but not of the modulating N-terminal domain (AF-1) []. Together with NCOA1, it is required to control energy balance between white and brown adipose tissues [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Picard F
Year: 2002
Journal: Cell
Title: SRC-1 and TIF2 control energy balance between white and brown adipose tissues.
Volume: 111
Issue: 7
Pages: 931-41
Publication
First Author: Voegel JJ
Year: 1998
Journal: EMBO J
Title: The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways.
Volume: 17
Issue: 2
Pages: 507-19
Publication
First Author: Qin J
Year: 2014
Journal: J Clin Invest
Title: Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer.
Volume: 124
Issue: 11
Pages: 5013-26
Protein
Organism: Mus musculus/domesticus
Length: 592  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1462  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1393  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1393  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1393  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 115  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: true
Publication
First Author: Leo C
Year: 2000
Journal: Gene
Title: The SRC family of nuclear receptor coactivators.
Volume: 245
Issue: 1
Pages: 1-11
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190849
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ncoa2
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190849
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ncoa2
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190849
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ncoa2
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190849
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ncoa2
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190849
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ncoa2
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190849
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ncoa2
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6178804
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190849
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ncoa2
Detected: true
Specimen Num: 7
Protein
Organism: Mus musculus/domesticus
Length: 873  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 114  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 233  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: false
Publication
First Author: Naiman S
Year: 2019
Journal: Cell Rep
Title: SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα.
Volume: 29
Issue: 12
Pages: 4127-4143.e8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Schuler M
Year: 2005
Journal: Genesis
Title: Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse.
Volume: 41
Issue: 4
Pages: 165-70
Publication
First Author: Zhu B
Year: 2015
Journal: Mol Cell
Title: Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading.
Volume: 60
Issue: 5
Pages: 769-783
Publication
First Author: Chinenov Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Role of transcriptional coregulator GRIP1 in the anti-inflammatory actions of glucocorticoids.
Volume: 109
Issue: 29
Pages: 11776-81
Publication
First Author: Nam DH
Year: 2019
Journal: FASEB J
Title: Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function.
Volume: 33
Issue: 1
Pages: 711-721
Publication
First Author: Fleet T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: SRC-2 orchestrates polygenic inputs for fine-tuning glucose homeostasis.
Volume: 112
Issue: 44
Pages: E6068-77
Publication
First Author: Mödder UI
Year: 2009
Journal: J Biol Chem
Title: Skeletal consequences of deletion of steroid receptor coactivator-2/transcription intermediary factor-2.
Volume: 284
Issue: 28
Pages: 18767-77
Publication
First Author: Dasgupta S
Year: 2015
Journal: J Clin Invest
Title: Coactivator SRC-2-dependent metabolic reprogramming mediates prostate cancer survival and metastasis.
Volume: 125
Issue: 3
Pages: 1174-88
Publication
First Author: Reineke EL
Year: 2012
Journal: PLoS One
Title: SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart.
Volume: 7
Issue: 12
Pages: e53395
Publication
First Author: Patchev AV
Year: 2007
Journal: FASEB J
Title: Insidious adrenocortical insufficiency underlies neuroendocrine dysregulation in TIF-2 deficient mice.
Volume: 21
Issue: 1
Pages: 231-8
Publication
First Author: Chinenov Y
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: GRIP1-associated SET-domain methyltransferase in glucocorticoid receptor target gene expression.
Volume: 105
Issue: 51
Pages: 20185-90
Publication
First Author: Nicolaides NC
Year: 2015
Journal: Eur J Clin Invest
Title: A novel mutation of the hGR gene causing Chrousos syndrome.
Volume: 45
Issue: 8
Pages: 782-91
Publication
First Author: Xia J
Year: 2005
Journal: J Biol Chem
Title: Structural determinants of constitutive androstane receptor required for its glucocorticoid receptor interacting protein-1-mediated nuclear accumulation.
Volume: 280
Issue: 8
Pages: 7285-93
Publication
First Author: Puustinen R
Year: 2001
Journal: Eur J Endocrinol
Title: Localization of glucocorticoid receptor interacting protein 1 in murine tissues using two novel polyclonal antibodies.
Volume: 145
Issue: 3
Pages: 323-33
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:2673899
Age: embryonic day 12.0
Specimen Label: E12
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2673899
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2673899
Age: postnatal adult
Specimen Label: brain
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2673899
Age: postnatal adult
Specimen Label: heart
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2673899
Age: postnatal adult
Specimen Label: lung
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557728
Stage: TS28
Assay Id: MGI:2673899
Age: postnatal adult
Specimen Label: muscle
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:2673899
Age: postnatal adult
Specimen Label: skin
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:34006
Assay Type: Northern blot
Annotation Date: 2003-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2673899
Age: postnatal adult
Specimen Label: spleen
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816730
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816730
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816730
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816730
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816730
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816730
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816730
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3815926
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816730
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5698804
Assay Type: RT-PCR
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:5700055
Age: embryonic day 13.5
Specimen Label: E13.5 +
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5698804
Assay Type: RT-PCR
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689526
Stage: TS26
Assay Id: MGI:5700055
Age: embryonic day 18.5
Specimen Label: E18.5
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5698804
Assay Type: RT-PCR
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689528
Stage: TS28
Assay Id: MGI:5700055
Age: postnatal day 8
Specimen Label: P8
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5698805
Assay Type: Northern blot
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:5700056
Age: embryonic day 13.5
Specimen Label: total
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5698805
Assay Type: Northern blot
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689521
Stage: TS21
Assay Id: MGI:5700056
Age: embryonic day 13.5
Specimen Label: polyA
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5698809
Assay Type: Western blot
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5700057
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5698809
Assay Type: Western blot
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:5700057
Age: embryonic day 15.5
Specimen Label: cx
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5698809
Assay Type: Western blot
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Stage: TS23
Assay Id: MGI:5700057
Age: embryonic day 15.5
Specimen Label: ge
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5698809
Assay Type: Western blot
Annotation Date: 2015-12-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684623
Stage: TS23
Assay Id: MGI:5700057
Age: embryonic day 15.5
Specimen Label: lv
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:5698809
Assay Type: Western blot
Annotation Date: 2015-12-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185723
Stage: TS23
Assay Id: MGI:5700057
Age: embryonic day 15.5
Specimen Label: body
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1633228
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Blood
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3276028
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Bone Marrow
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Brain
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Heart
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Intestines
Specimen Num: 5
GXD Expression    
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Kidney
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Liver
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5898301
Assay Type: RT-PCR
Annotation Date: 2017-05-29
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5898310
Age: postnatal week 8
Image: 2
Specimen Label: Lung
Specimen Num: 8