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Search results 1 to 100 out of 492 for Ncoa3

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: Nuclear receptor coactivator 3 (NCOA3, also known as AIB1) belongs to the SRC/p160 nuclear receptor coactivator family, which contains proteins that are ligand-dependent transcription factors []. These receptors can function as molecular switches [].NCOA3 is overexpressed in a fraction of breast cancers and has been linked to prognosis and tamoxifen resistance [, ].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein
Organism: Mus musculus/domesticus
Length: 1353  
Fragment?: true
Publication
First Author: Xu J
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: The steroid receptor coactivator SRC-3 (p/CIP/RAC3/AIB1/ACTR/TRAM-1) is required for normal growth, puberty, female reproductive function, and mammary gland development.
Volume: 97
Issue: 12
Pages: 6379-84
Publication
First Author: Percharde M
Year: 2012
Journal: Genes Dev
Title: Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming.
Volume: 26
Issue: 20
Pages: 2286-98
Publication
First Author: Chen X
Year: 2010
Journal: Mol Endocrinol
Title: The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival.
Volume: 24
Issue: 10
Pages: 1917-34
Publication
First Author: Chang AK
Year: 2012
Journal: Oncol Lett
Title: The role of AIB1 in breast cancer.
Volume: 4
Issue: 4
Pages: 588-594
Publication
First Author: Leo C
Year: 2000
Journal: Gene
Title: The SRC family of nuclear receptor coactivators.
Volume: 245
Issue: 1
Pages: 1-11
Protein
Organism: Mus musculus/domesticus
Length: 1398  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1403  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1397  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 1402  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 585  
Fragment?: true
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190850
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Ncoa3
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190850
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Ncoa3
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190850
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Ncoa3
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190850
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Ncoa3
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190850
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Ncoa3
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190850
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Ncoa3
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6178805
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190850
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Ncoa3
Detected: true
Specimen Num: 7
Publication
First Author: Wang Z
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Regulation of somatic growth by the p160 coactivator p/CIP.
Volume: 97
Issue: 25
Pages: 13549-54
Publication
First Author: Torres-Arzayus MI
Year: 2004
Journal: Cancer Cell
Title: High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene.
Volume: 6
Issue: 3
Pages: 263-74
Publication
First Author: Wang Z
Year: 2006
Journal: Cell Metab
Title: Critical roles of the p160 transcriptional coactivators p/CIP and SRC-1 in energy balance.
Volume: 3
Issue: 2
Pages: 111-22
Publication
First Author: Wang Z
Year: 2012
Journal: PLoS One
Title: The transcriptional coactivators p/CIP and SRC-1 control insulin resistance through IRS1 in obesity models.
Volume: 7
Issue: 7
Pages: e36961
Publication
First Author: Wu Z
Year: 2012
Journal: J Biol Chem
Title: Role of nuclear receptor coactivator 3 (Ncoa3) in pluripotency maintenance.
Volume: 287
Issue: 45
Pages: 38295-304
Publication
First Author: Uranishi K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Esrrb directly binds to Gata6 promoter and regulates its expression with Dax1 and Ncoa3.
Volume: 478
Issue: 4
Pages: 1720-5
Publication
First Author: Demarest SJ
Year: 2002
Journal: Nature
Title: Mutual synergistic folding in recruitment of CBP/p300 by p160 nuclear receptor coactivators.
Volume: 415
Issue: 6871
Pages: 549-53
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Liu Z
Year: 2008
Journal: Int J Biol Sci
Title: Generation and validation of a mouse line with a floxed SRC-3/AIB1 allele for conditional knockout.
Volume: 4
Issue: 4
Pages: 202-7
Publication
First Author: Tien JC
Year: 2014
Journal: Int J Biol Sci
Title: The steroid receptor coactivator-3 is required for developing neuroendocrine tumor in the mouse prostate.
Volume: 10
Issue: 10
Pages: 1116-27
Publication
First Author: York B
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology.
Volume: 107
Issue: 24
Pages: 11122-7
Publication
First Author: Chung AC
Year: 2007
Journal: Cancer Res
Title: Genetic ablation of the amplified-in-breast cancer 1 inhibits spontaneous prostate cancer progression in mice.
Volume: 67
Issue: 12
Pages: 5965-75
Publication
First Author: Kuang SQ
Year: 2004
Journal: Cancer Res
Title: AIB1/SRC-3 deficiency affects insulin-like growth factor I signaling pathway and suppresses v-Ha-ras-induced breast cancer initiation and progression in mice.
Volume: 64
Issue: 5
Pages: 1875-85
Publication  
First Author: Wang W
Year: 2021
Journal: Oxid Med Cell Longev
Title: SRC-3 Knockout Attenuates Myocardial Injury Induced by Chronic Intermittent Hypoxia in Mice.
Volume: 2021
Pages: 6372430
Publication
First Author: Yan J
Year: 2006
Journal: Cancer Res
Title: Steroid receptor coactivator-3 and activator protein-1 coordinately regulate the transcription of components of the insulin-like growth factor/AKT signaling pathway.
Volume: 66
Issue: 22
Pages: 11039-46
Publication
First Author: Kuang SQ
Year: 2005
Journal: Cancer Res
Title: Mice lacking the amplified in breast cancer 1/steroid receptor coactivator-3 are resistant to chemical carcinogen-induced mammary tumorigenesis.
Volume: 65
Issue: 17
Pages: 7993-8002
Publication
First Author: Chen Q
Year: 2010
Journal: J Immunol
Title: Steroid receptor coactivator 3 is required for clearing bacteria and repressing inflammatory response in Escherichia coli-induced septic peritonitis.
Volume: 185
Issue: 9
Pages: 5444-52
Publication
First Author: Nikolai BC
Year: 2021
Journal: Sci Rep
Title: Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs.
Volume: 11
Issue: 1
Pages: 3441
Publication  
First Author: Xia X
Year: 2021
Journal: Int Immunopharmacol
Title: SRC-3 deficiency protects host from Listeria monocytogenes infection through increasing ROS production and decreasing lymphocyte apoptosis.
Volume: 96
Pages: 107625
Publication
First Author: Qin L
Year: 2008
Journal: Mol Cell Biol
Title: The AIB1 oncogene promotes breast cancer metastasis by activation of PEA3-mediated matrix metalloproteinase 2 (MMP2) and MMP9 expression.
Volume: 28
Issue: 19
Pages: 5937-50
Publication
First Author: Al-Otaiby M
Year: 2012
Journal: Am J Pathol
Title: Role of the nuclear receptor coactivator AIB1/SRC-3 in angiogenesis and wound healing.
Volume: 180
Issue: 4
Pages: 1474-84
Publication
First Author: Hu M
Year: 2018
Journal: Blood
Title: SRC-3 is involved in maintaining hematopoietic stem cell quiescence by regulation of mitochondrial metabolism in mice.
Volume: 132
Issue: 9
Pages: 911-923
Publication
First Author: Xiao Y
Year: 2010
Journal: Glia
Title: Genetic ablation of steroid receptor coactivator-3 promotes PPAR-beta-mediated alternative activation of microglia in experimental autoimmune encephalomyelitis.
Volume: 58
Issue: 8
Pages: 932-42
Publication
First Author: Leung K
Year: 2003
Journal: Cells Tissues Organs
Title: Targeted expression of activated Rac3 in mammary epithelium leads to defective postlactational involution and benign mammary gland lesions.
Volume: 175
Issue: 2
Pages: 72-83
Publication
First Author: Tilli MT
Year: 2005
Journal: Mol Endocrinol
Title: Overexpression of an N-terminally truncated isoform of the nuclear receptor coactivator amplified in breast cancer 1 leads to altered proliferation of mammary epithelial cells in transgenic mice.
Volume: 19
Issue: 3
Pages: 644-56
Publication
First Author: Avivar A
Year: 2006
Journal: FEBS Lett
Title: Moderate overexpression of AIB1 triggers pre-neoplastic changes in mammary epithelium.
Volume: 580
Issue: 22
Pages: 5222-6
Publication
First Author: Torres-Arzayus MI
Year: 2006
Journal: Cancer Res
Title: Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland.
Volume: 66
Issue: 23
Pages: 11381-8
Publication
First Author: Jin J
Year: 2019
Journal: Acta Biochim Biophys Sin (Shanghai)
Title: SRC3 expressed in bone marrow mesenchymal stem cells promotes the development of multiple myeloma.
Volume: 51
Issue: 12
Pages: 1258-1266
GXD Expression      
Probe: MGI:3615028
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616657
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3615028
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616657
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Female
Emaps: EMAPS:3102528
Stage: TS28
Assay Id: MGI:3816731
Age: postnatal
Specimen Label: Metaphase II
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360422
Stage: TS02
Assay Id: MGI:3816731
Age: embryonic day 1.5
Specimen Label: 2-cell embryo
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360433
Stage: TS03
Assay Id: MGI:3816731
Age: embryonic day 2.0
Specimen Label: 4-cell embryo
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360443
Stage: TS03
Assay Id: MGI:3816731
Age: embryonic day 2.5
Specimen Label: 8-cell embryo
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360453
Stage: TS03
Assay Id: MGI:3816731
Age: embryonic day 3.0
Specimen Label: Morula
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360464
Stage: TS04
Assay Id: MGI:3816731
Age: embryonic day 3.5
Specimen Label: E3.5 blastocyst
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:360465
Stage: TS05
Assay Id: MGI:3816731
Age: embryonic day 4.5
Specimen Label: E4.5 blastocyst
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:3815927
Assay Type: RT-PCR
Annotation Date: 2008-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160415
Stage: TS05
Assay Id: MGI:3816731
Age: embryonic day 4.5
Specimen Label: E4.5 inner cell mass
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-1
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-A1-2
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-1
Detected: true
Specimen Num: 3
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-A2-2
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-1
Detected: true
Specimen Num: 5
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-B1-2
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-1
Detected: true
Specimen Num: 7
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-B2-2
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-1
Detected: true
Specimen Num: 9
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-C1-2
Detected: true
Specimen Num: 10
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-1
Detected: true
Specimen Num: 11
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160362
Stage: TS02
Assay Id: MGI:5289396
Age: embryonic day 1.5
Specimen Label: 2-cell-C2-2
Detected: true
Specimen Num: 12
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289396
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-1
Detected: true
Specimen Num: 13
GXD Expression      
Probe: MGI:5288924
Assay Type: RT-PCR
Annotation Date: 2011-10-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:318643
Stage: TS03
Assay Id: MGI:5289396
Age: embryonic day 2.0
Specimen Label: 4-cell-A1-2
Detected: true
Specimen Num: 14