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Search results 1 to 97 out of 97 for Ndufaf2

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
91942 | NDUFAF2
Type: gene
Organism: human
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Gene
100489348 | ndufaf2
Type: gene
Organism: frog, western clawed
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Gene
361894 | Ndufaf2
Type: gene
Organism: rat
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Gene
478067 | NDUFAF2
Type: gene
Organism: dog, domestic
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Gene
461857 | NDUFAF2
Type: gene
Organism: chimpanzee
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Gene
767961 | NDUFAF2
Type: gene
Organism: cattle
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Gene
769549 | NDUFAF2
Type: gene
Organism: chicken
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Gene
100003850 | ndufaf2
Type: gene
Organism: zebrafish
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Gene
693441 | NDUFAF2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1922847 | Ndufaf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
727919 | NDUFAF2P1
Type: gene
Organism: human
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Gene
100130783 | NDUFAF2P2
Type: gene
Organism: human
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Publication
23702311 | J:201547
 
First Author: Schlehe JS
Year: 2013
Journal: Neurobiol Dis
Title: The mitochondrial disease associated protein Ndufaf2 is dispensable for Complex-1 assembly but critical for the regulation of oxidative stress.
Volume: 58
Pages: 57-67
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Publication
32335026 | J:297197
First Author: Adjobo-Hermans MJW
Year: 2020
Journal: Biochim Biophys Acta Bioenerg
Title: NDUFS4 deletion triggers loss of NDUFA12 in Ndufs4-/- mice and Leigh syndrome patients: A stabilizing role for NDUFAF2.
Volume: 1861
Issue: 8
Pages: 148213
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Protein Coding Gene
MGP_CAROLIEiJ_G0018877 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020923 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020872 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0020662 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1922847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021308 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020181 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0020624 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020747 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020730 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020822 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020758 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020239 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015948 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019756 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15774466 | J:99538
First Author: Tsuneoka M
Year: 2005
Journal: J Biol Chem
Title: A novel Myc-target gene, mimitin, that is involved in cell proliferation of esophageal squamous cell carcinoma.
Volume: 280
Issue: 20
Pages: 19977-85
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Publication
22587331 | J:192991
First Author: Hanzelka K
Year: 2012
Journal: Biochem J
Title: Effects of the novel mitochondrial protein mimitin in insulin-secreting cells.
Volume: 445
Issue: 3
Pages: 349-59
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GXD Expression
GXD Expression
   
Probe: MGI:7546900
Assay Type: RT-PCR
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546957
Age: embryonic day 18.5
Image: 5
Specimen Label: WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7546900
Assay Type: RT-PCR
Annotation Date: 2023-11-08
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3550526
Stage: TS26
Assay Id: MGI:7546957
Age: embryonic day 18.5
Image: 5
Specimen Label: CKO
Detected: true
Specimen Num: 2
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Publication
1737990 | J:1921
First Author: Timsit SG
Year: 1992
Journal: J Neurochem
Title: DM-20 mRNA is expressed during the embryonic development of the nervous system of the mouse.
Volume: 58
Issue: 3
Pages: 1172-5
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Publication
36127325 | J:329220
First Author: Chen Y
Year: 2022
Journal: Cell Death Dis
Title: Hnrnpk maintains chondrocytes survival and function during growth plate development via regulating Hif1α-glycolysis axis.
Volume: 13
Issue: 9
Pages: 803
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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DO Term
DOID:0112075 | nuclear type mitochondrial complex I deficiency 10
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Allele
Ndufaf2<tm1.1Itl> | MGI:5521199
Name: NADH:ubiquinone oxidoreductase complex assembly factor 2; targeted mutation 1.1, inGenious Targeting Laboratory
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:5694436 | B6.129S(C)-Ndufaf2<tm1.1Itl>/J
Attribute String: congenic, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Ndufaf2/Ndufaf2
Background: involves: 129S/SvEv * BALB/cJ
Zygosity: hm
Has Mutant Allele: true
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Protein
Q7TMF3
Organism: Mus musculus/domesticus
Length: 145  
Fragment?: false
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Protein
Q59J78
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
A0A286YE75
Organism: Mus musculus/domesticus
Length: 83  
Fragment?: true
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Protein
A0A286YE33
Organism: Mus musculus/domesticus
Length: 77  
Fragment?: false
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Protein
A0A0R4J275
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: false
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Protein
Q5M9K5
Organism: Mus musculus/domesticus
Length: 149  
Fragment?: false
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Protein
Q3TLI6
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Protein
F6RBR6
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: false
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Protein
Q8BME2
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: false
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Publication
14741580 | -
First Author: Friedrich T
Year: 2004
Journal: Biochim Biophys Acta
Title: The gross structure of the respiratory complex I: a Lego System.
Volume: 1608
Issue: 1
Pages: 1-9
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Publication
23648483 | -
First Author: Pereira B
Year: 2013
Journal: Mol Cell Biol
Title: Novel insights into the role of Neurospora crassa NDUFAF2, an evolutionarily conserved mitochondrial complex I assembly factor.
Volume: 33
Issue: 13
Pages: 2623-34
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Protein Domain
IPR007763 | NDUFA12
Type: Family
Description: NADH:ubiquinone oxidoreductase (complex I) () is a respiratory-chain enzyme that catalyses the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane (NADH + ubiquinone = NAD+ + ubiquinol) []. Complex I is a major source of reactive oxygen species (ROS) that are predominantly formed by electron transfer from FMNH(2). Complex I is found in bacteria, cyanobacteria (as a NADH-plastoquinone oxidoreductase), archaea [], mitochondria, and in the hydrogenosome, a mitochondria-derived organelle. In general, the bacterial complex consists of 14 different subunits, while the mitochondrial complex contains homologues to these subunits in addition to approximately 31 additional proteins [].This entry includes the NADH dehydrogenase [ubiquinone]1 alpha subcomplex subunit 12 (NDUFA12) and the NADH dehydrogenase [ubiquinone]1 alpha subcomplex assembly factor 2 (NDUFAF2). NDUFA12 is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) [, ]. NDUFA12 is believed not to be involved in catalysis []. NDUFAF2 is a paralogue of the structural subunit NDUFA12 and functions as an assembly factor [].
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Publication
34583519 | J:341477
First Author: Zhang G
Year: 2021
Journal: Circulation
Title: Integrated Stress Response Couples Mitochondrial Protein Translation With Oxidative Stress Control.
Volume: 144
Issue: 18
Pages: 1500-1515
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Publication
12611891 | -
First Author: Murray J
Year: 2003
Journal: J Biol Chem
Title: The subunit composition of the human NADH dehydrogenase obtained by rapid one-step immunopurification.
Volume: 278
Issue: 16
Pages: 13619-22
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Publication
27626371 | -
First Author: Stroud DA
Year: 2016
Journal: Nature
Title: Accessory subunits are integral for assembly and function of human mitochondrial complex I.
Volume: 538
Issue: 7623
Pages: 123-126
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Publication
18394423 | -
First Author: Schneider D
Year: 2008
Journal: Biochim Biophys Acta
Title: Assembly of the Escherichia coli NADH:ubiquinone oxidoreductase (complex I).
Volume: 1777
Issue: 7-8
Pages: 735-9
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Publication
1470679 | -
First Author: Walker JE
Year: 1992
Journal: Q Rev Biophys
Title: The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains.
Volume: 25
Issue: 3
Pages: 253-324
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Publication
10940377 | -
First Author: Friedrich T
Year: 2000
Journal: FEBS Lett
Title: The respiratory complex I of bacteria, archaea and eukarya and its module common with membrane-bound multisubunit hydrogenases.
Volume: 479
Issue: 1-2
Pages: 1-5
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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