| Type |
Details |
Score |
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
frog, western clawed |
|
•
•
•
•
•
|
| Gene |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
dog, domestic |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chimpanzee |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
cattle |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
chicken |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Domain |
| Type: |
Family |
| Description: |
Nectin-1 is involved in cell adhesion and synaptogegesis [, , ]. The molecule also serves as a functional receptor for Herpes simplex virus []and other alphaherpesviruses [].Nectins are single-pass type I membrane glycoproteins belonging to the immunoglobulin superfamily. They are characterised by three Ig-like domains (a distal IgV domain and two IgC domains) in the ectodomain, followed by a transmembrane region and a cytoplasmic tail []. Unlike cadherins, nectins are Ca2+-independent cell adhesion molecules that mediate not only homotypic but also heterotypic cell-cell adhesion []. The cytoplasmic tail of nectins possesses a conserved afadin-binding motif, except for nectin-4 which binds the PDZ domain of afadin at its carboxyl terminus. Afadin connects nectins to F-actin and the actin cytoskeleton [, , ]. |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Geng X |
| Year: |
2016 |
| Journal: |
Genes Cells |
| Title: |
Regulatory role of the cell adhesion molecule nectin-1 in GABAergic inhibitory synaptic transmission in the CA3 region of mouse hippocampus. |
| Volume: |
21 |
| Issue: |
1 |
| Pages: |
88-98 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mizoguchi A |
| Year: |
2002 |
| Journal: |
J Cell Biol |
| Title: |
Nectin: an adhesion molecule involved in formation of synapses. |
| Volume: |
156 |
| Issue: |
3 |
| Pages: |
555-65 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lim ST |
| Year: |
2012 |
| Journal: |
J Neurochem |
| Title: |
Ectodomain shedding of nectin-1 regulates the maintenance of dendritic spine density. |
| Volume: |
120 |
| Issue: |
5 |
| Pages: |
741-51 |
|
•
•
•
•
•
|
| Gene |
| Type: |
gene |
| Organism: |
human |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Menotti L |
| Year: |
2001 |
| Journal: |
Virology |
| Title: |
Comparison of murine and human nectin1 binding to herpes simplex virus glycoprotein D (gD) reveals a weak interaction of murine nectin1 to gD and a gD-dependent pathway of entry. |
| Volume: |
282 |
| Issue: |
2 |
| Pages: |
256-66 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:6711098 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2021-05-17 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1784221 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:6711109 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Co-localization between Nectin1 and 3 was detected. |
| Specimen Label: |
4F/F' |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
515
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
114
 |
| Fragment?: |
true |
|
•
•
•
•
•
|
| Protein |
| Organism: |
Mus musculus/domesticus |
| Length: |
447
 |
| Fragment?: |
false |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takai Y |
| Year: |
2008 |
| Journal: |
Annu Rev Cell Dev Biol |
| Title: |
The immunoglobulin-like cell adhesion molecule nectin and its associated protein afadin. |
| Volume: |
24 |
|
| Pages: |
309-42 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mandai K |
| Year: |
2015 |
| Journal: |
Curr Top Dev Biol |
| Title: |
Nectins and nectin-like molecules in development and disease. |
| Volume: |
112 |
|
| Pages: |
197-231 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lu G |
| Year: |
2014 |
| Journal: |
J Virol |
| Title: |
Crystal structure of herpes simplex virus 2 gD bound to nectin-1 reveals a conserved mode of receptor recognition. |
| Volume: |
88 |
| Issue: |
23 |
| Pages: |
13678-88 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Geraghty RJ |
| Year: |
1998 |
| Journal: |
Science |
| Title: |
Entry of alphaherpesviruses mediated by poliovirus receptor-related protein 1 and poliovirus receptor. |
| Volume: |
280 |
| Issue: |
5369 |
| Pages: |
1618-20 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Mandai K |
| Year: |
1997 |
| Journal: |
J Cell Biol |
| Title: |
Afadin: A novel actin filament-binding protein with one PDZ domain localized at cadherin-based cell-to-cell adherens junction. |
| Volume: |
139 |
| Issue: |
2 |
| Pages: |
517-28 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Takahashi K |
| Year: |
1999 |
| Journal: |
J Cell Biol |
| Title: |
Nectin/PRR: an immunoglobulin-like cell adhesion molecule recruited to cadherin-based adherens junctions through interaction with Afadin, a PDZ domain-containing protein. |
| Volume: |
145 |
| Issue: |
3 |
| Pages: |
539-49 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Wu C |
| Year: |
2022 |
| Journal: |
Transl Psychiatry |
| Title: |
Disrupted presynaptic nectin1-based neuronal adhesion in the entorhinal-hippocampal circuit contributes to early-life stress-induced memory deficits. |
| Volume: |
12 |
| Issue: |
1 |
| Pages: |
141 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Pang J |
| Year: |
2021 |
| Journal: |
Cell Rep |
| Title: |
NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression. |
| Volume: |
34 |
| Issue: |
2 |
| Pages: |
108603 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Lough KJ |
| Year: |
2020 |
| Journal: |
Development |
| Title: |
Disruption of the nectin-afadin complex recapitulates features of the human cleft lip/palate syndrome CLPED1. |
| Volume: |
147 |
| Issue: |
21 |
|
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus caroli |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus pahari |
|
•
•
•
•
•
|
| Protein Coding Gene |
| Type: |
protein_coding_gene |
| Organism: |
Mus spretus |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Menotti L |
| Year: |
2000 |
| Journal: |
Proc Natl Acad Sci U S A |
| Title: |
The murine homolog of human Nectin1delta serves as a species nonspecific mediator for entry of human and animal alpha herpesviruses in a pathway independent of a detectable binding to gD. |
| Volume: |
97 |
| Issue: |
9 |
| Pages: |
4867-72 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Shukla D |
| Year: |
2000 |
| Journal: |
J Virol |
| Title: |
Striking similarity of murine nectin-1alpha to human nectin-1alpha (HveC) in sequence and activity as a glycoprotein D receptor for alphaherpesvirus entry. |
| Volume: |
74 |
| Issue: |
24 |
| Pages: |
11773-81 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Suzuki K |
| Year: |
2000 |
| Journal: |
Nat Genet |
| Title: |
Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia. |
| Volume: |
25 |
| Issue: |
4 |
| Pages: |
427-30 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Fujiwara T |
| Year: |
2015 |
| Journal: |
Mol Cell Neurosci |
| Title: |
Nectin-1 spots regulate the branching of olfactory mitral cell dendrites. |
| Volume: |
68 |
|
| Pages: |
143-50 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Slade JA |
| Year: |
2016 |
| Journal: |
PLoS One |
| Title: |
Host Nectin-1 Promotes Chlamydial Infection in the Female Mouse Genital Tract, but Is Not Required for Infection in a Novel Male Murine Rectal Infection Model. |
| Volume: |
11 |
| Issue: |
8 |
| Pages: |
e0160511 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Tomioka Y |
| Year: |
2024 |
| Journal: |
J Vet Med Sci |
| Title: |
Single amino acid mutation of nectin-1 provides remarkable resistance against lethal pseudorabies virus infection in mice. |
| Volume: |
86 |
| Issue: |
1 |
| Pages: |
120-127 |
|
•
•
•
•
•
|
| Publication |
| First Author: |
Inoue T |
| Year: |
2015 |
| Journal: |
J Comp Neurol |
| Title: |
Nectin-1 spots as a novel adhesion apparatus that tethers mitral cell lateral dendrites in a dendritic meshwork structure of the developing mouse olfactory bulb. |
| Volume: |
523 |
| Issue: |
12 |
| Pages: |
1824-39 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7464604 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-04-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1783827 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:7464638 |
| Age: |
postnatal day 2 |
| Image: |
1 |
|
| Specimen Label: |
P2 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7464604 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2023-04-20 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1783828 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7464638 |
| Age: |
postnatal day 24 |
| Image: |
1 |
|
| Specimen Label: |
P24 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7713238 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736222 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:7713316 |
| Age: |
embryonic day 14.0 |
| Image: |
5 |
|
| Specimen Label: |
wild-type |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7713238 |
| Assay Type: |
RT-PCR |
| Annotation Date: |
2024-08-29 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736222 |
|
| Stage: |
TS22 |
| Assay Id: |
MGI:7713316 |
| Age: |
embryonic day 14.0 |
| Image: |
5 |
|
| Specimen Label: |
p63-/- |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689421 |
|
| Stage: |
TS21 |
| Assay Id: |
MGI:7852589 |
| Age: |
embryonic day 13.5 |
|
|
| Specimen Label: |
E13.5 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689423 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7852589 |
| Age: |
embryonic day 15.5 |
|
|
| Specimen Label: |
E15.5 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689425 |
|
| Stage: |
TS25 |
| Assay Id: |
MGI:7852589 |
| Age: |
embryonic day 17.5 |
|
|
| Specimen Label: |
E17.5 |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689427 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:7852589 |
| Age: |
postnatal day 1 |
|
|
| Specimen Label: |
P1 |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7852589 |
| Age: |
postnatal day 6 |
|
|
| Specimen Label: |
P6 |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7852589 |
| Age: |
postnatal day 10 |
|
|
| Specimen Label: |
P10 |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7852232 |
| Assay Type: |
Western blot |
| Annotation Date: |
2025-01-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1689428 |
|
| Stage: |
TS28 |
| Assay Id: |
MGI:7852589 |
| Age: |
postnatal day 60 |
|
|
| Specimen Label: |
P60 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1760623 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.5 |
| Image: |
3d |
|
| Specimen Label: |
3d |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-07-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1830223 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:5571480 |
| Age: |
embryonic day 15.5 |
| Image: |
1B |
| Note: |
Expression is in stellate reticulum cells. |
| Specimen Label: |
1B |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-07-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1830225 |
| Pattern: |
Regionally restricted |
| Stage: |
TS25 |
| Assay Id: |
MGI:5571480 |
| Age: |
embryonic day 17.5 |
| Image: |
1C |
| Note: |
Expression is in stellate reticulum cells. |
| Specimen Label: |
1C |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7489649 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-06-16 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2840723 |
|
| Stage: |
TS23 |
| Assay Id: |
MGI:7489953 |
| Age: |
embryonic day 15.0 |
|
|
| Specimen Label: |
1A |
| Detected: |
false |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791923 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.0 |
| Image: |
3a |
|
| Specimen Label: |
3a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1791923 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.0 |
| Image: |
3b |
|
| Specimen Label: |
3b |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7621924 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-04-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691021 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7623258 |
| Age: |
embryonic day 13.5 |
|
| Note: |
Expression is at adherens junctions. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571592 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2014-07-09 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3288027 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5571735 |
| Age: |
postnatal day 0 |
| Image: |
1H |
| Note: |
Expression is in ameloblasts and in stellate reticulum cells and is strong at their junction. |
| Specimen Label: |
1H |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-07-08 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:3288028 |
| Pattern: |
Non-Uniform |
| Stage: |
TS28 |
| Assay Id: |
MGI:5571480 |
| Age: |
postnatal day 10 |
| Image: |
4A |
| Note: |
Expression is strong in ameloblasts and weak in the stratum intermedium. |
| Specimen Label: |
4A |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7489649 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2023-06-16 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:2767823 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:7489953 |
| Age: |
embryonic day 15.0 |
|
|
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7621924 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-04-23 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1691321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7623243 |
| Age: |
embryonic day 13.5 |
| Image: |
1A |
| Note: |
Expression is at the lumenal surface of neuroepithelial cells. |
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.0 |
| Image: |
3a |
| Note: |
Expresion is in the medial edge epithelium of the palatal shelves. |
| Specimen Label: |
3a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736323 |
| Pattern: |
Regionally restricted |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.0 |
| Image: |
3c |
| Note: |
Expresion is in the medial edge epithelium of the palatal shelves. |
| Specimen Label: |
3c |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7713222 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-08-29 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7713314 |
| Age: |
embryonic day 13.5 |
| Image: |
5E |
| Note: |
Expressed at the junction between the periderm/basal cells in the palatal epithelia. |
| Specimen Label: |
5E |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7713222 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-08-29 |
| Strength: |
Strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736321 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:7713314 |
| Age: |
embryonic day 13.5 |
| Image: |
5F |
| Note: |
Expressed at the junction between the periderm/basal cells in the palatal epithelia, observed along the basal epithelial layer. |
| Specimen Label: |
5F |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7713222 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-08-29 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7713314 |
| Age: |
embryonic day 13.5 |
| Image: |
5G |
| Note: |
Expression are markedly down-regulated. |
| Specimen Label: |
5G |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:7713222 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2024-08-29 |
| Strength: |
Weak |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1736321 |
| Pattern: |
Not Specified |
| Stage: |
TS21 |
| Assay Id: |
MGI:7713314 |
| Age: |
embryonic day 13.5 |
| Image: |
5H |
| Note: |
Expression are markedly down-regulated. Expression at the basal/periderm junction was absent. |
| Specimen Label: |
5H |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1759726 |
| Pattern: |
Regionally restricted |
| Stage: |
TS26 |
| Assay Id: |
MGI:5641218 |
| Age: |
embryonic day 18.0 |
|
| Note: |
Expression at apical surface of developing cochlea. |
| Specimen Label: |
S4A Nectin-1 |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1759722 |
| Pattern: |
Regionally restricted |
| Stage: |
TS22 |
| Assay Id: |
MGI:5641214 |
| Age: |
embryonic day 14.0 |
|
| Note: |
Expression at junctions between auditory epithelia. |
| Specimen Label: |
not shown |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641218 |
| Age: |
postnatal day 1 |
|
| Note: |
Expression predominantly in outer hair cells along entire length of cochlea. |
| Specimen Label: |
S4B Nectin-1 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
| Note: |
Expression only at boundaries between between hair cells and supporting cells, not at junctions between supporting cells. |
| Specimen Label: |
1 Nectin-1 |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Patchy |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
|
| Specimen Label: |
3A WT |
| Detected: |
true |
| Specimen Num: |
3 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Absent |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
|
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
|
| Specimen Label: |
3B Nectin-1 KO |
| Detected: |
false |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
| Note: |
Authors report expression remained unchanged compared with wild type mice. |
| Specimen Label: |
3C Nectin-2 KO |
| Detected: |
true |
| Specimen Num: |
5 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
| Note: |
Expression abnormally concentrated at boundaries between hair cells. No expression at junctions between hair cells and supporting cells. |
| Specimen Label: |
3D nectin-3 KO |
| Detected: |
true |
| Specimen Num: |
6 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906124 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:5641214 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression at apical surface of auditory epithelium in middle turn of cochlea. Authors report expression at E16 similar to that at P1. |
| Specimen Label: |
S2A Nectin-1 |
| Detected: |
true |
| Specimen Num: |
7 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906124 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:5641214 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression localized on apical side of lateral membranes of hair cells and supporting cells. |
| Specimen Label: |
S3A Nectin-1 |
| Detected: |
true |
| Specimen Num: |
8 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906124 |
| Pattern: |
Regionally restricted |
| Stage: |
TS24 |
| Assay Id: |
MGI:5641214 |
| Age: |
embryonic day 16.0 |
|
| Note: |
Expression localized on apical side of lateral membranes of hair cells and supporting cells. |
| Specimen Label: |
S3D Nectin-1 |
| Detected: |
true |
| Specimen Num: |
9 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
| Note: |
Expression abnormally concentrated at boundaries between hair cells. No expression at junctions between hair cells and supporting cells. |
| Specimen Label: |
S5A Nectin-1 |
| Detected: |
true |
| Specimen Num: |
10 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5641204 |
| Assay Type: |
Immunohistochemistry |
| Annotation Date: |
2015-06-19 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1906127 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5641214 |
| Age: |
postnatal day 1 |
|
| Note: |
Expression abnormally concentrated at boundaries between hair cells. No expression at junctions between hair cells and supporting cells. |
| Specimen Label: |
S5B Nectin-1 |
| Detected: |
true |
| Specimen Num: |
11 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-07-08 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1794221 |
| Pattern: |
Regionally restricted |
| Stage: |
TS21 |
| Assay Id: |
MGI:5571480 |
| Age: |
embryonic day 13.5 |
| Image: |
1A |
| Note: |
Expression is in the center. |
| Specimen Label: |
1A |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:5571478 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2014-07-08 |
| Strength: |
Very strong |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1794227 |
| Pattern: |
Regionally restricted |
| Stage: |
TS27 |
| Assay Id: |
MGI:5571480 |
| Age: |
postnatal day 0 |
| Image: |
1G |
| Note: |
Expression is in the stratum intermedium, some expression was seen in ameloblasts. |
| Specimen Label: |
1G |
| Detected: |
true |
| Specimen Num: |
4 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752523 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.0 |
| Image: |
3a |
| Note: |
Shown is a section of the head. |
| Specimen Label: |
3a |
| Detected: |
true |
| Specimen Num: |
1 |
|
•
•
•
•
•
|
| GXD Expression |
| Probe: |
MGI:3721151 |
| Assay Type: |
RNA in situ |
| Annotation Date: |
2007-09-12 |
| Strength: |
Present |
| Sex: |
Not Specified |
| Emaps: |
EMAPS:1752523 |
| Pattern: |
Not Specified |
| Stage: |
TS23 |
| Assay Id: |
MGI:3721152 |
| Age: |
embryonic day 15.0 |
| Image: |
3b |
|
| Specimen Label: |
3b |
| Detected: |
true |
| Specimen Num: |
2 |
|
•
•
•
•
•
|