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Search results 1 to 100 out of 1450 for Nedd8

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
4738 | NEDD8
Type: gene
Organism: human
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Gene
704026 | LOC704026
Type: gene
Organism: macaque, rhesus
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Gene
480265 | NEDD8
Type: gene
Organism: dog, domestic
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Gene
100608126 | NEDD8
Type: gene
Organism: chimpanzee
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Gene
368667 | nedd8
Type: gene
Organism: zebrafish
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Gene
25490 | Nedd8
Type: gene
Organism: rat
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Gene
286796 | NEDD8
Type: gene
Organism: cattle
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Gene
100858776 | NEDD8
Type: gene
Organism: chicken
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Gene
715763 | NEDD8
Type: gene
Organism: macaque, rhesus
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Gene
549727 | nedd8
Type: gene
Organism: frog, western clawed
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Protein
Q3UI46
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: false
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Protein
Q3TY05
Organism: Mus musculus/domesticus
Length: 68  
Fragment?: true
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Protein Coding Gene
MGI:97301 | Nedd8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
P29595
Organism: Mus musculus/domesticus
Length: 81  
Fragment?: false
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Protein
A0A2I3BRG0
Organism: Mus musculus/domesticus
Length: 18  
Fragment?: true
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Publication
9353319 | J:44037
First Author: Kamitani T
Year: 1997
Journal: J Biol Chem
Title: Characterization of NEDD8, a developmentally down-regulated ubiquitin-like protein.
Volume: 272
Issue: 45
Pages: 28557-62
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Publication
15183309 | J:90626
First Author: Carrabino S
Year: 2004
Journal: Gene Expr Patterns
Title: Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8.
Volume: 4
Issue: 4
Pages: 423-31
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Publication
11696557 | J:72808
First Author: Tateishi K
Year: 2001
Journal: J Cell Biol
Title: The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice.
Volume: 155
Issue: 4
Pages: 571-9
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Publication
25452302 | J:224304
First Author: Segovia JA
Year: 2015
Journal: Mol Cell Biol
Title: Nedd8 regulates inflammasome-dependent caspase-1 activation.
Volume: 35
Issue: 3
Pages: 582-97
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Gene
100128775 | NEDD8P1
Type: gene
Organism: human
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Publication
38177106 | J:346004
First Author: Jiang Y
Year: 2024
Journal: Cell Death Dis
Title: Targeting NEDD8 suppresses surgical stress-facilitated metastasis of colon cancer via restraining regulatory T cells.
Volume: 15
Issue: 1
Pages: 8
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Publication
12215427 | J:80189
First Author: Antenos M
Year: 2002
Journal: J Biol Chem
Title: Interaction with Nedd8, a ubiquitin-like protein, enhances the transcriptional activity of the aryl hydrocarbon receptor.
Volume: 277
Issue: 46
Pages: 44028-34
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UniProt Feature
UniProt Feature
Begin: 1
Description: NEDD8
Type: chain
End: 76
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Publication
28522566 | J:244502
First Author: Zhu Z
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Nedd8 modification of Cullin-5 regulates lipopolysaccharide-induced acute lung injury.
Volume: 313
Issue: 1
Pages: L104-L114
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Publication
27119228 | J:311917
First Author: Qiu X
Year: 2016
Journal: Oncotarget
Title: NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.
Volume: 7
Issue: 21
Pages: 31440-53
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Publication
16735510 | J:116476
First Author: Oved S
Year: 2006
Journal: J Biol Chem
Title: Conjugation to Nedd8 instigates ubiquitylation and down-regulation of activated receptor tyrosine kinases.
Volume: 281
Issue: 31
Pages: 21640-51
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Publication
25581363 | J:262411
First Author: Vogl AM
Year: 2015
Journal: Nat Neurosci
Title: Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition.
Volume: 18
Issue: 2
Pages: 239-51
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GO Term
GO:0019788 | NEDD8 transferase activity
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Gene
8883 | NAE1
Type: gene
Organism: human
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Gene
123228 | SENP8
Type: gene
Organism: human
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Gene
100533706 | LOC100533706
Type: gene
Organism: human
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Publication
8395831 | -
First Author: Kumar S
Year: 1993
Journal: Biochem Biophys Res Commun
Title: Cloning of a cDNA which encodes a novel ubiquitin-like protein.
Volume: 195
Issue: 1
Pages: 393-9
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Publication
10597293 | -
First Author: Hori T
Year: 1999
Journal: Oncogene
Title: Covalent modification of all members of human cullin family proteins by NEDD8.
Volume: 18
Issue: 48
Pages: 6829-34
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Publication
1378265 | J:1344
First Author: Kumar S
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Identification of a set of genes with developmentally down-regulated expression in the mouse brain.
Volume: 185
Issue: 3
Pages: 1155-61
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Publication
29632206 | J:261328
First Author: Zou J
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Neddylation mediates ventricular chamber maturation through repression of Hippo signaling.
Volume: 115
Issue: 17
Pages: E4101-E4110
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Publication
33020269 | J:299730
First Author: Zhang L
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Neddylation is critical to cortical development by regulating Wnt/β-catenin signaling.
Volume: 117
Issue: 42
Pages: 26448-26459
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Gene
100296298 | LOC100296298
Type: gene
Organism: cattle
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Publication
12759363 | J:84722
First Author: Wu K
Year: 2003
Journal: J Biol Chem
Title: DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1.
Volume: 278
Issue: 31
Pages: 28882-91
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Publication
23267066 | J:192598
First Author: Jin HS
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Neddylation pathway regulates T-cell function by targeting an adaptor protein Shc and a protein kinase Erk signaling.
Volume: 110
Issue: 2
Pages: 624-9
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Publication
10806345 | J:62211
First Author: Yeh ET
Year: 2000
Journal: Gene
Title: Ubiquitin-like proteins: new wines in new bottles.
Volume: 248
Issue: 1-2
Pages: 1-14
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Publication
20937703 | J:166065
First Author: Flomerfelt FA
Year: 2010
Journal: J Exp Med
Title: Tbata modulates thymic stromal cell proliferation and thymus function.
Volume: 207
Issue: 11
Pages: 2521-32
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Publication
25326537 | J:218023
First Author: Curtis VF
Year: 2015
Journal: FASEB J
Title: Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses.
Volume: 29
Issue: 1
Pages: 208-15
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GO Term
GO:0019781 | NEDD8 activating enzyme activity
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Publication
25624478 | J:219561
First Author: Batuello CN
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Src phosphorylation converts Mdm2 from a ubiquitinating to a neddylating E3 ligase.
Volume: 112
Issue: 6
Pages: 1749-54
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Publication
18826954 | J:143467
First Author: Kim AY
Year: 2008
Journal: J Biol Chem
Title: SCCRO (DCUN1D1) is an essential component of the E3 complex for neddylation.
Volume: 283
Issue: 48
Pages: 33211-20
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Protein Coding Gene
MGI:2384561 | Nae1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0019309 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021361 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021296 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021324 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97301 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021762 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020623 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021192 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021174 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021266 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021198 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020370 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030326 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020198 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:1101808
Assay Type: Northern blot
Annotation Date: 2003-04-07
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2653693
Age: embryonic day 7.0
Image: 3
Specimen Label: 7 days
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1101808
Assay Type: Northern blot
Annotation Date: 2003-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2653693
Age: embryonic day 11.0
Image: 3
Specimen Label: 11 days
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:1101808
Assay Type: Northern blot
Annotation Date: 2003-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2653693
Age: embryonic day 15.0
Image: 3
Specimen Label: 15 days
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1101808
Assay Type: Northern blot
Annotation Date: 2003-04-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2653693
Age: embryonic day 17.0
Image: 3
Specimen Label: 17 days
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603917
Stage: TS17
Assay Id: MGI:3046265
Age: embryonic day 10.5
Image: 1
Specimen Label: E10.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3046265
Age: embryonic day 12.5
Image: 1
Specimen Label: E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3046265
Age: embryonic day 14.5
Image: 1
Specimen Label: E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:3046265
Age: embryonic day 15.5
Image: 1
Specimen Label: E15.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:3046265
Age: embryonic day 17.5
Image: 1
Specimen Label: E17.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:3046271
Age: postnatal adult
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3046271
Age: postnatal adult
Image: 1
Specimen Label: Kidney
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3046271
Age: postnatal adult
Image: 1
Specimen Label: Uterus
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1876828
Stage: TS28
Assay Id: MGI:3046271
Age: postnatal adult
Image: 1
Specimen Label: Thymus
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3046271
Age: postnatal adult
Image: 1
Specimen Label: Brain
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3046192
Assay Type: Northern blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3046271
Age: postnatal adult
Image: 1
Specimen Label: Lung
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: brain
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: cerebellum
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: spleen
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1796228
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: ovary
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: uterus
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: kidney
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1842628
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: adrenal gland
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: lung
Detected: true
Specimen Num: 8
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•
GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: heart
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:3046212
Assay Type: Western blot
Annotation Date: 2004-07-30
Strength: Present
Sex: Female
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:3046292
Age: postnatal day 33
Image: 2
Specimen Label: skeletal muscle
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185816
Stage: TS16
Assay Id: MGI:5776739
Age: embryonic day 10.0
Specimen Label: E10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3185818
Stage: TS18
Assay Id: MGI:5776739
Age: embryonic day 11.0
Specimen Label: E11
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:5776739
Age: embryonic day 13.0
Specimen Label: E13
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:5776739
Age: embryonic day 15.0
Specimen Label: E15
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689425
Stage: TS25
Assay Id: MGI:5776739
Age: embryonic day 17.0
Specimen Label: E17
Detected: true
Specimen Num: 5
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•
•
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GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:5776739
Age: postnatal day 1
Specimen Label: N1
Detected: true
Specimen Num: 6
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5776739
Age: postnatal day 5
Specimen Label: N5
Detected: true
Specimen Num: 7
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•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:21017
Assay Type: Northern blot
Annotation Date: 2016-06-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5776739
Age: postnatal adult
Specimen Label: adult
Detected: true
Specimen Num: 8
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6198340
Assay Type: Western blot
Annotation Date: 2018-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:6198368
Age: postnatal day 0.5
Image: 1
Specimen Label: P0.5
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:6198340
Assay Type: Western blot
Annotation Date: 2018-09-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6198368
Age: postnatal day 4
Image: 1
Specimen Label: P4
Detected: true
Specimen Num: 2
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•
•
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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