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Search results 1 to 99 out of 99 for Net1

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Hits by Category

Type Details Score
Gene
10276 | NET1
Type: gene
Organism: human
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Gene
507365 | NET1
Type: gene
Organism: cattle
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Gene
416693 | NET1
Type: gene
Organism: chicken
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Gene
493607 | net1
Type: gene
Organism: zebrafish
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Gene
712080 | NET1
Type: gene
Organism: macaque, rhesus
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Gene
780346 | net1
Type: gene
Organism: frog, western clawed
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Gene
307098 | Net1
Type: gene
Organism: rat
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Gene
487147 | NET1
Type: gene
Organism: dog, domestic
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Gene
450277 | NET1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1927138 | Net1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7587799
Assay Type: RNA in situ
Annotation Date: 2024-02-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1775621
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:7587818
Age: embryonic day 13.0
Image: 1C Net1
Note: Expression polarized basally in outer epithelal cells.`
Specimen Label: 1C Net1
Detected: true
Specimen Num: 1
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Publication
25321414 | J:218290
First Author: Zuo Y
Year: 2014
Journal: Mol Endocrinol
Title: The RhoGEF Net1 is required for normal mammary gland development.
Volume: 28
Issue: 12
Pages: 1948-60
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Publication
29173011 | J:343938
First Author: Zuo Y
Year: 2020
Journal: Small GTPases
Title: Genetic deletion of the Rho GEF Net1 impairs mouse macrophage motility and actin cytoskeletal organization.
Volume: 11
Issue: 4
Pages: 293-300
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Publication
19586902 | J:154886
First Author: Carr HS
Year: 2009
Journal: J Biol Chem
Title: Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity.
Volume: 284
Issue: 36
Pages: 24269-80
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Publication
29769144 | J:317239
First Author: Zuo Y
Year: 2018
Journal: Breast Cancer Res
Title: Contributions of the RhoA guanine nucleotide exchange factor Net1 to polyoma middle T antigen-mediated mammary gland tumorigenesis and metastasis.
Volume: 20
Issue: 1
Pages: 41
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Publication
33740419 | J:305520
First Author: Robinson RA
Year: 2021
Journal: Cell
Title: Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling.
Volume: 184
Issue: 8
Pages: 2103-2120.e31
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Publication
9670022 | J:48926
First Author: Alberts AS
Year: 1998
Journal: EMBO J
Title: Activation of RhoA and SAPK/JNK signalling pathways by the RhoA-specific exchange factor mNET1.
Volume: 17
Issue: 14
Pages: 4075-85
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Publication
23184663 | J:194204
First Author: Carr HS
Year: 2013
Journal: Mol Cell Biol
Title: Rac1 controls the subcellular localization of the Rho guanine nucleotide exchange factor Net1A to regulate focal adhesion formation and cell spreading.
Volume: 33
Issue: 3
Pages: 622-34
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Publication
15684429 | J:98481
First Author: Alberts AS
Year: 2005
Journal: J Biol Chem
Title: PAK1 negatively regulates the activity of the Rho exchange factor NET1.
Volume: 280
Issue: 13
Pages: 12152-61
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Protein Coding Gene
MGP_CAROLIEiJ_G0018197 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0020199 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0020155 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0020130 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0020138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019942 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1927138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0019482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019909 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0020026 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0020011 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0020100 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0020047 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020613 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0019244 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019540 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0019245 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0019049 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:6358422
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6358584
Age: embryonic day 11.0
Image: S8A
Specimen Label: S8A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:6358422
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6358584
Age: embryonic day 11.0
Image: S8C
Specimen Label: S8C
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:6358422
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6358584
Age: embryonic day 11.0
Image: S8D
Note: Expression was downregulated in muscle cells in the conditional mutant.
Specimen Label: S8D
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:6358422
Assay Type: RNA in situ
Annotation Date: 2019-09-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640618
Pattern: Not Specified
Stage: TS18
Assay Id: MGI:6358584
Age: embryonic day 11.0
Image: S8B
Note: Expression was downregulated in muscle cells in the conditional mutant.
Specimen Label: S8B
Detected: true
Specimen Num: 2
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Publication
11350080 | J:200334
First Author: Dobrosotskaya IY
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Identification of mNET1 as a candidate ligand for the first PDZ domain of MAGI-1.
Volume: 283
Issue: 4
Pages: 969-75
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Publication
9535835 | J:46957
First Author: Alberts AS
Year: 1998
Journal: J Biol Chem
Title: Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7.
Volume: 273
Issue: 15
Pages: 8616-22
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Publication
22987639 | J:187741
First Author: Hu JK
Year: 2012
Journal: Genes Dev
Title: Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation.
Volume: 26
Issue: 18
Pages: 2088-102
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Publication
38103869 | J:344117
 
First Author: Wang S
Year: 2023
Journal: Cells Dev
Title: Microtubule-dependent apical polarization of basement membrane matrix mRNAs in mouse epithelial cells.
Volume: 177
Pages: 203898
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Publication
11389549 | J:69146
First Author: Hwang SY
Year: 2001
Journal: Mol Reprod Dev
Title: Expression of genes involved in mammalian meiosis during the transition from egg to embryo.
Volume: 59
Issue: 2
Pages: 144-58
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Publication
35864088 | J:326958
First Author: Sapir T
Year: 2022
Journal: Nat Commun
Title: Heterogeneous nuclear ribonucleoprotein U (HNRNPU) safeguards the developing mouse cortex.
Volume: 13
Issue: 1
Pages: 4209
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Publication
22174793 | J:182258
First Author: Taher L
Year: 2011
Journal: PLoS One
Title: Global gene expression analysis of murine limb development.
Volume: 6
Issue: 12
Pages: e28358
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Publication
- | J:157064
     
First Author: University of California, Davis
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the University of California, Davis
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
21373644 | -
First Author: Srougi MC
Year: 2011
Journal: PLoS One
Title: The nuclear guanine nucleotide exchange factors Ect2 and Net1 regulate RhoB-mediated cell death after DNA damage.
Volume: 6
Issue: 2
Pages: e17108
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Publication
27910850 | -
First Author: Wei S
Year: 2017
Journal: Cell Res
Title: The guanine nucleotide exchange factor Net1 facilitates the specification of dorsal cell fates in zebrafish embryos by promoting maternal β-catenin activation.
Volume: 27
Issue: 2
Pages: 202-225
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Publication
11839749 | -
First Author: Schmidt A
Year: 2002
Journal: J Biol Chem
Title: The Rho exchange factor Net1 is regulated by nuclear sequestration.
Volume: 277
Issue: 17
Pages: 14581-8
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Publication
12898711 | -
First Author: Koltovaya NA
Year: 2003
Journal: Yeast
Title: NET1 and HFI1 genes of yeast mediate both chromosome maintenance and mitochondrial rho(-) mutagenesis.
Volume: 20
Issue: 11
Pages: 955-71
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Interaction Experiment
Garcia-Mata R (2007)
Description: The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.
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Publication
17938206 | -
First Author: García-Mata R
Year: 2007
Journal: Mol Cell Biol
Title: The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.
Volume: 27
Issue: 24
Pages: 8683-97
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Publication
22343628 | -
First Author: Vessichelli M
Year: 2012
Journal: J Biol Chem
Title: Neuroepithelial transforming gene 1 (Net1) binds to caspase activation and recruitment domain (CARD)- and membrane-associated guanylate kinase-like domain-containing (CARMA) proteins and regulates nuclear factor κB activation.
Volume: 287
Issue: 17
Pages: 13722-30
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Protein Domain
IPR037853 | Net1_PH
Type: Domain
Description: Net1 (also called ArhGEF8) is a RhoA-specific GEF (guanine nucleotide exchange factors). Net1 binds to caspase activation and recruitment domain (CARD)- and membrane-associated guanylate kinase-like domain-containing (CARMA) proteins and regulates nuclear factor kB activation []. In nucleus, it also regulates RhoB-mediated cell death after DNA damage []. Net1 and RhoA have been shown to play important roles in various aspects of vertebrate embryonic development and organogenesis [].Net1 contains a catalytic Dbl homology (DH) domain and an adjacent pleckstrin homology (PH) domain flanked by N- and C-terminal extensions []. This entry represents the PH domain. The DH and PH domains are necessary for binding to the GTPase and stimulating nucleotide exchange activity [].
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Publication
18923139 | -
First Author: Waples WG
Year: 2009
Journal: Mol Biol Cell
Title: Putting the brake on FEAR: Tof2 promotes the biphasic release of Cdc14 phosphatase during mitotic exit.
Volume: 20
Issue: 1
Pages: 245-55
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Publication
18595708 | -
First Author: Geil C
Year: 2008
Journal: Curr Biol
Title: A nucleolus-localized activator of Cdc14 phosphatase supports rDNA segregation in yeast mitosis.
Volume: 18
Issue: 13
Pages: 1001-5
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Publication
24006256 | -
First Author: Yu ZY
Year: 2013
Journal: J Cell Sci
Title: Fission yeast nucleolar protein Dnt1 regulates G2/M transition and cytokinesis by downregulating Wee1 kinase.
Volume: 126
Issue: Pt 21
Pages: 4995-5004
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Protein Domain
IPR043185 | Dnt1/Tof2/Net1
Type: Family
Description: This entry represents a group of fungal nucleolar proteins, including Dnt1 from fission yeasts and Tof2/Net1 from budding yeasts. Net1 regulates the homologous MEN (mitotic exit network) pathway by sequestering Cdc14 phosphatase in the nucleolus before mitotic exit []. Dnt1 is a homologue of Net1. Both Dnt1 and Net1 negatively regulate the homologous SIN (septation initiation network) and MEN pathways. They are both required for rDNA silencing and minichromosome maintenance. However, Net1 regulates the MEN through the Cdc14 phosphatase, while Dnt1 inhibit SIN signaling independently of Clp1 (a Cdc14-family phosphatase) [].Tof2 is a paralogue of Net1. It is required for rDNA silencing and mitotic rDNA condensation [, ]. It coordinates the biphasic release of Cdc14 during anaphase by restraining a population of Cdc14 in the nucleolus [].
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Publication
17538026 | -
First Author: Jin QW
Year: 2007
Journal: Mol Biol Cell
Title: The nucleolar Net1/Cfi1-related protein Dnt1 antagonizes the septation initiation network in fission yeast.
Volume: 18
Issue: 8
Pages: 2924-34
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Publication
19362534 | -
First Author: Johzuka K
Year: 2009
Journal: Mol Cell
Title: The cis element and factors required for condensin recruitment to chromosomes.
Volume: 34
Issue: 1
Pages: 26-35
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Protein
Q9Z206
Organism: Mus musculus/domesticus
Length: 595  
Fragment?: false
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Protein
Q3USZ7
Organism: Mus musculus/domesticus
Length: 541  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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