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Search results 1 to 100 out of 912 for Nf1

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
4763 | NF1
Type: gene
Organism: human
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Gene
280877 | NF1
Type: gene
Organism: cattle
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Gene
396085 | NF1
Type: gene
Organism: chicken
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Gene
712911 | NF1
Type: gene
Organism: macaque, rhesus
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Gene
100493879 | nf1
Type: gene
Organism: frog, western clawed
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Gene
key_36205 | NF1
Type: gene
Organism: pig, domestic
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Gene
24592 | Nf1
Type: gene
Organism: rat
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Gene
480618 | NF1
Type: gene
Organism: dog, domestic
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Gene
454566 | NF1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:97306 | Nf1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
Probe: MGI:7384504
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384544
Age: embryonic day 15.5
Image: 5a Nf1 WT
Note: Widely expressed throughout cortical primordium
Specimen Label: 5a Nf1 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7384504
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-15
Strength: Present
Sex: Male
Emaps: EMAPS:3284223
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7384544
Age: embryonic day 15.5
Image: 5a Nf1 Fmr1 KO
Note: No difference compared with wild type.
Specimen Label: 5a Nf1 Fmr1 KO
Detected: true
Specimen Num: 2
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Publication
16288202 | J:108781
First Author: Wu M
Year: 2006
Journal: Oncogene
Title: Nf1 haploinsufficiency augments angiogenesis.
Volume: 25
Issue: 16
Pages: 2297-303
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Gene
111811965 | LOC111811965
Type: gene
Organism: human
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GXD Expression
GXD Expression
   
Probe: MGI:1330081
Assay Type: Northern blot
Annotation Date: 1999-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1330576
Age: embryonic day 12.5
Image: 2
Specimen Label: NF1 +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:1330081
Assay Type: Northern blot
Annotation Date: 1999-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1330576
Age: embryonic day 12.5
Image: 2
Specimen Label: NF1 -/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:1330081
Assay Type: Northern blot
Annotation Date: 1999-02-24
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:1330576
Age: embryonic day 12.5
Image: 2
Specimen Label: NF1 +/-
Detected: true
Specimen Num: 2
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Publication
16226708 | J:103509
First Author: Chao RC
Year: 2005
Journal: Cancer Cell
Title: Therapy-induced malignant neoplasms in Nf1 mutant mice.
Volume: 8
Issue: 4
Pages: 337-48
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Gene
108281182 | LOC108281182
Type: gene
Organism: human
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Gene
108281180 | LOC108281180
Type: gene
Organism: human
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Gene
108281170 | LOC108281170
Type: gene
Organism: human
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Gene
108281169 | LOC108281169
Type: gene
Organism: human
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Gene
108281181 | LOC108281181
Type: gene
Organism: human
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Publication
12393498 | J:82128
First Author: Ingram DA
Year: 2003
Journal: Blood
Title: Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.
Volume: 101
Issue: 5
Pages: 1984-6
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Publication
24211110 | J:205128
First Author: Stansfield BK
Year: 2014
Journal: Am J Pathol
Title: Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.
Volume: 184
Issue: 1
Pages: 79-85
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Publication
10678181 | J:60155
First Author: Birnbaum RA
Year: 2000
Journal: Mol Cell
Title: Nf1 and Gmcsf interact in myeloid leukemogenesis.
Volume: 5
Issue: 1
Pages: 189-95
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Publication
23171796 | J:198252
First Author: Maertens O
Year: 2013
Journal: Cancer Discov
Title: Elucidating distinct roles for NF1 in melanomagenesis.
Volume: 3
Issue: 3
Pages: 338-49
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Publication
24163128 | J:206219
First Author: Sullivan K
Year: 2014
Journal: Hum Mol Genet
Title: NF1 is a critical regulator of muscle development and metabolism.
Volume: 23
Issue: 5
Pages: 1250-9
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Publication
14695164 | J:87063
First Author: Bajenaru ML
Year: 2003
Journal: Cancer Res
Title: Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity.
Volume: 63
Issue: 24
Pages: 8573-7
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Publication
11425624 | J:70635
First Author: Hafezparast M
Year: 2001
Journal: Trends Mol Med
Title: NF1 mice: smaller brains but no tumours.
Volume: 7
Issue: 7
Pages: 285
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Publication
10339466 | J:55413
First Author: Mahgoub N
Year: 1999
Journal: Blood
Title: Myeloid malignancies induced by alkylating agents in Nf1 mice.
Volume: 93
Issue: 11
Pages: 3617-23
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Publication
10383727 | J:55742
First Author: Atit RP
Year: 1999
Journal: J Invest Dermatol
Title: The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts.
Volume: 112
Issue: 6
Pages: 835-42
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Publication
8563750 | J:31568
First Author: Largaespada DA
Year: 1996
Journal: Nat Genet
Title: Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
Volume: 12
Issue: 2
Pages: 137-43
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Publication
26908603 | J:233023
First Author: Toonen JA
Year: 2016
Journal: Hum Mol Genet
Title: NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1.
Volume: 25
Issue: 9
Pages: 1703-13
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Publication
30479396 | J:268119
First Author: Brosseau JP
Year: 2018
Journal: Nat Commun
Title: NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation.
Volume: 9
Issue: 1
Pages: 5014
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Publication
11544276 | J:73064
First Author: Zhang Y
Year: 2001
Journal: J Clin Invest
Title: Quantitative effects of Nf1 inactivation on in vivo hematopoiesis.
Volume: 108
Issue: 5
Pages: 709-15
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Publication
34040258 | J:308741
First Author: Pan Y
Year: 2021
Journal: Nature
Title: NF1 mutation drives neuronal activity-dependent initiation of optic glioma.
Volume: 594
Issue: 7862
Pages: 277-282
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Publication
16093333 | J:128643
First Author: Wang Y
Year: 2005
Journal: J Neurophysiol
Title: Sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability.
Volume: 94
Issue: 6
Pages: 3670-6
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Publication
17967772 | J:142994
First Author: Xu J
Year: 2007
Journal: Circulation
Title: NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.
Volume: 116
Issue: 19
Pages: 2148-56
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Publication
23221337 | J:194161
First Author: Chang T
Year: 2013
Journal: J Clin Invest
Title: Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.
Volume: 123
Issue: 1
Pages: 335-9
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Publication
27923908 | J:238781
First Author: Toonen JA
Year: 2017
Journal: J Exp Med
Title: Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology.
Volume: 214
Issue: 1
Pages: 17-25
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Publication
12469121 | J:80323
First Author: Gitler AD
Year: 2003
Journal: Nat Genet
Title: Nf1 has an essential role in endothelial cells.
Volume: 33
Issue: 1
Pages: 75-9
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Publication
17090653 | J:123850
First Author: Kim A
Year: 2007
Journal: Blood
Title: Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice.
Volume: 109
Issue: 4
Pages: 1687-91
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Publication
28423318 | J:250028
First Author: López-Juárez A
Year: 2017
Journal: Cell Rep
Title: Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior.
Volume: 19
Issue: 3
Pages: 545-557
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Publication
24035394 | J:203799
First Author: Mayes DA
Year: 2013
Journal: Cell Rep
Title: Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.
Volume: 4
Issue: 6
Pages: 1197-212
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Publication
22945628 | J:191670
First Author: Dai C
Year: 2012
Journal: J Clin Invest
Title: Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.
Volume: 122
Issue: 10
Pages: 3742-54
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Publication
28254468 | J:255126
 
First Author: Baht GS
Year: 2017
Journal: Bone
Title: Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair.
Volume: 98
Pages: 31-36
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Publication
18948576 | J:144622
First Author: Yin B
Year: 2009
Journal: Blood
Title: A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Volume: 113
Issue: 5
Pages: 1075-85
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Publication
25775093 | J:232916
First Author: Kobus K
Year: 2015
Journal: PLoS One
Title: Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient.
Volume: 10
Issue: 3
Pages: e0119030
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Publication
30226831 | J:270524
First Author: Zhang P
Year: 2018
Journal: J Clin Invest
Title: Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.
Volume: 128
Issue: 12
Pages: 5383-5398
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Publication
14982883 | J:90973
First Author: Le DT
Year: 2004
Journal: Blood
Title: Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.
Volume: 103
Issue: 11
Pages: 4243-50
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Publication
24535670 | J:213447
First Author: de Bruin EC
Year: 2014
Journal: Cancer Discov
Title: Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.
Volume: 4
Issue: 5
Pages: 606-19
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Publication
11297510 | J:68558
First Author: Zhu Y
Year: 2001
Journal: Genes Dev
Title: Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain.
Volume: 15
Issue: 7
Pages: 859-76
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Publication
9852579 | J:68953
First Author: Klesse LJ
Year: 1998
Journal: J Neurosci
Title: p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons.
Volume: 18
Issue: 24
Pages: 10420-8
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Publication
21551249 | J:173625
First Author: Mayes DA
Year: 2011
Journal: Cancer Res
Title: Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation.
Volume: 71
Issue: 13
Pages: 4675-85
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Publication
16906226 | J:114455
First Author: Ismat FA
Year: 2006
Journal: J Clin Invest
Title: The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice.
Volume: 116
Issue: 9
Pages: 2378-84
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Publication
19710506 | J:153839
First Author: Cutts BA
Year: 2009
Journal: Blood
Title: Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Volume: 114
Issue: 17
Pages: 3629-32
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Publication
17582688 | J:125803
First Author: Powers JF
Year: 2007
Journal: Neuroscience
Title: Pheochromocytomas in Nf1 knockout mice express a neural progenitor gene expression profile.
Volume: 147
Issue: 4
Pages: 928-37
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190868
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Nf1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190868
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Nf1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190868
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Nf1
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190868
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Nf1
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190868
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Nf1
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190868
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Nf1
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6178953
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190868
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Nf1
Detected: true
Specimen Num: 7
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Publication
32610136 | J:300703
First Author: Shih YT
Year: 2020
Journal: Cell Rep
Title: Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice.
Volume: 31
Issue: 13
Pages: 107835
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Publication
19228926 | J:148716
First Author: Koenigsmann J
Year: 2009
Journal: Blood
Title: Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias.
Volume: 113
Issue: 19
Pages: 4690-701
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Publication
24075988 | J:203786
First Author: Ribeiro S
Year: 2013
Journal: Cell Rep
Title: Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve.
Volume: 5
Issue: 1
Pages: 126-36
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Publication
32243842 | J:302646
First Author: Anastasaki C
Year: 2020
Journal: Stem Cell Reports
Title: Human iPSC-Derived Neurons and Cerebral Organoids Establish Differential Effects of Germline NF1 Gene Mutations.
Volume: 14
Issue: 4
Pages: 541-550
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Publication
17216419 | J:121636
First Author: Hawes JJ
Year: 2007
Journal: Neurogenetics
Title: Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies.
Volume: 8
Issue: 2
Pages: 121-30
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GXD Expression
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1303279
Age: embryonic day 11.5
Image: 11.5
Note: Nf1 expression was seen in the limb mesenchyme.
Specimen Label: 11.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:1303279
Age: embryonic day 12.5
Image: 12.5
Note: Nf1 expression was seen in the limb mesenchyme.
Specimen Label: 12.5
Detected: true
Specimen Num: 3
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Publication
21199799 | J:167772
First Author: Nakamura JL
Year: 2011
Journal: Cancer Res
Title: Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice.
Volume: 71
Issue: 1
Pages: 106-15
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Publication
23071067 | J:193638
First Author: Choi G
Year: 2012
Journal: Cancer Res
Title: Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms.
Volume: 72
Issue: 24
Pages: 6425-34
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Publication
27482814 | J:234172
First Author: Li K
Year: 2016
Journal: Dis Model Mech
Title: Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I.
Volume: 9
Issue: 7
Pages: 759-67
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Publication
20200958 | J:183363
First Author: Wang W
Year: 2010
Journal: J Bone Miner Res
Title: Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Volume: 25
Issue: 7
Pages: 1658-67
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Publication
21757497 | J:175684
First Author: Wang W
Year: 2011
Journal: Hum Mol Genet
Title: Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Volume: 20
Issue: 20
Pages: 3910-24
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Publication
22868293 | J:193350
First Author: El Khassawna T
Year: 2012
Journal: Bone
Title: Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia.
Volume: 51
Issue: 4
Pages: 651-60
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Publication
31128207 | J:287830
 
First Author: Shofty B
Year: 2019
Journal: Neurobiol Dis
Title: Autism-associated Nf1 deficiency disrupts corticocortical and corticostriatal functional connectivity in human and mouse.
Volume: 130
Pages: 104479
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Publication
16314489 | J:104342
First Author: Zhu Y
Year: 2005
Journal: Development
Title: Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
Volume: 132
Issue: 24
Pages: 5577-88
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Publication
37140985 | J:336671
 
First Author: Jiang C
Year: 2023
Journal: J Clin Invest
Title: Basement membrane proteins in extracellular matrix characterize NF1 neurofibroma development and response to MEK inhibitor.
Volume: 133
Issue: 12
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Publication
22535408 | J:183991
First Author: Baek ST
Year: 2012
Journal: Development
Title: Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation.
Volume: 139
Issue: 11
Pages: 2040-9
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Publication
27773571 | J:302678
First Author: Xie K
Year: 2016
Journal: Curr Biol
Title: NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.
Volume: 26
Issue: 22
Pages: 2992-3003
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Publication
25242307 | J:219424
First Author: Molosh AI
Year: 2014
Journal: Nat Neurosci
Title: Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase.
Volume: 17
Issue: 11
Pages: 1583-90
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Publication
18242511 | J:131916
First Author: Wu J
Year: 2008
Journal: Cancer Cell
Title: Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.
Volume: 13
Issue: 2
Pages: 105-16
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Publication
28673309 | J:313308
First Author: Chen L
Year: 2017
Journal: Mol Brain
Title: Abnormal circadian oscillation of hippocampal MAPK activity and power spectrums in NF1 mutant mice.
Volume: 10
Issue: 1
Pages: 29
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Publication
16098465 | J:101868
First Author: Zhu Y
Year: 2005
Journal: Cancer Cell
Title: Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.
Volume: 8
Issue: 2
Pages: 119-30
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Publication
18242513 | J:131914
First Author: Joseph NM
Year: 2008
Journal: Cancer Cell
Title: The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells.
Volume: 13
Issue: 2
Pages: 129-40
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Publication
25917016 | J:317773
First Author: Rhodes SD
Year: 2015
Journal: J Bone Miner Res
Title: Nf1 Haploinsufficiency Alters Myeloid Lineage Commitment and Function, Leading to Deranged Skeletal Homeostasis.
Volume: 30
Issue: 10
Pages: 1840-51
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Publication
29139538 | J:251722
First Author: Summers MA
Year: 2017
Journal: Int J Dev Biol
Title: Limitations of the Pax7-creERT2 transgene for driving deletion of Nf1 in adult mouse muscle.
Volume: 61
Issue: 8-9
Pages: 531-536
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Publication
17314307 | J:118374
First Author: Romero MI
Year: 2007
Journal: J Neurosci
Title: Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury.
Volume: 27
Issue: 8
Pages: 2124-34
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Publication
31664505 | J:310924
First Author: Yu Y
Year: 2020
Journal: Acta Neuropathol
Title: NF1 patient missense variants predict a role for ATM in modifying neurofibroma initiation.
Volume: 139
Issue: 1
Pages: 157-174
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Publication
14739366 | J:88133
First Author: Gitler AD
Year: 2004
Journal: Pediatr Res
Title: Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia.
Volume: 55
Issue: 4
Pages: 581-4
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Publication
19056885 | J:142040
First Author: Parrinello S
Year: 2008
Journal: Genes Dev
Title: NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F.
Volume: 22
Issue: 23
Pages: 3335-48
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Publication
36351408 | J:331107
First Author: Ramakrishnan G
Year: 2022
Journal: Cell Rep
Title: NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.
Volume: 41
Issue: 6
Pages: 111623
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Publication
22118770 | J:178926
First Author: Tan M
Year: 2011
Journal: Dev Cell
Title: SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.
Volume: 21
Issue: 6
Pages: 1062-76
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Publication
23858101 | J:234760
First Author: Dodd RD
Year: 2013
Journal: Mol Cancer Ther
Title: NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition.
Volume: 12
Issue: 9
Pages: 1906-17
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Publication
28425622 | J:312342
First Author: Kamiya N
Year: 2017
Journal: J Bone Miner Res
Title: Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype.
Volume: 32
Issue: 8
Pages: 1716-1726
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Publication
9796699 | J:52704
First Author: Mangues R
Year: 1998
Journal: Oncogene
Title: NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity.
Volume: 17
Issue: 13
Pages: 1705-16
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Publication
25367036 | J:217419
First Author: Sanchez-Ortiz E
Year: 2014
Journal: Genes Dev
Title: NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development.
Volume: 28
Issue: 21
Pages: 2407-20
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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