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Search results 1 to 100 out of 813 for Nf1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wu M
Year: 2006
Journal: Oncogene
Title: Nf1 haploinsufficiency augments angiogenesis.
Volume: 25
Issue: 16
Pages: 2297-303
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Ingram DA
Year: 2003
Journal: Blood
Title: Leukemic potential of doubly mutant Nf1 and Wv hematopoietic cells.
Volume: 101
Issue: 5
Pages: 1984-6
Publication
First Author: Sullivan K
Year: 2014
Journal: Hum Mol Genet
Title: NF1 is a critical regulator of muscle development and metabolism.
Volume: 23
Issue: 5
Pages: 1250-9
Publication
First Author: Chao RC
Year: 2005
Journal: Cancer Cell
Title: Therapy-induced malignant neoplasms in Nf1 mutant mice.
Volume: 8
Issue: 4
Pages: 337-48
Publication
First Author: Bajenaru ML
Year: 2003
Journal: Cancer Res
Title: Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity.
Volume: 63
Issue: 24
Pages: 8573-7
Publication
First Author: Birnbaum RA
Year: 2000
Journal: Mol Cell
Title: Nf1 and Gmcsf interact in myeloid leukemogenesis.
Volume: 5
Issue: 1
Pages: 189-95
Publication
First Author: Stansfield BK
Year: 2014
Journal: Am J Pathol
Title: Ras-Mek-Erk signaling regulates Nf1 heterozygous neointima formation.
Volume: 184
Issue: 1
Pages: 79-85
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Maertens O
Year: 2013
Journal: Cancer Discov
Title: Elucidating distinct roles for NF1 in melanomagenesis.
Volume: 3
Issue: 3
Pages: 338-49
Publication
First Author: Largaespada DA
Year: 1996
Journal: Nat Genet
Title: Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
Volume: 12
Issue: 2
Pages: 137-43
Publication
First Author: Atit RP
Year: 1999
Journal: J Invest Dermatol
Title: The Nf1 tumor suppressor regulates mouse skin wound healing, fibroblast proliferation, and collagen deposited by fibroblasts.
Volume: 112
Issue: 6
Pages: 835-42
Publication
First Author: Toonen JA
Year: 2016
Journal: Hum Mol Genet
Title: NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1.
Volume: 25
Issue: 9
Pages: 1703-13
Publication
First Author: Hafezparast M
Year: 2001
Journal: Trends Mol Med
Title: NF1 mice: smaller brains but no tumours.
Volume: 7
Issue: 7
Pages: 285
Publication
First Author: Toonen JA
Year: 2017
Journal: J Exp Med
Title: Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology.
Volume: 214
Issue: 1
Pages: 17-25
Publication
First Author: Mahgoub N
Year: 1999
Journal: Blood
Title: Myeloid malignancies induced by alkylating agents in Nf1 mice.
Volume: 93
Issue: 11
Pages: 3617-23
Publication
First Author: Yin B
Year: 2009
Journal: Blood
Title: A retroviral mutagenesis screen reveals strong cooperation between Bcl11a overexpression and loss of the Nf1 tumor suppressor gene.
Volume: 113
Issue: 5
Pages: 1075-85
Publication
First Author: Brosseau JP
Year: 2018
Journal: Nat Commun
Title: NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation.
Volume: 9
Issue: 1
Pages: 5014
Publication
First Author: Zhang Y
Year: 2001
Journal: J Clin Invest
Title: Quantitative effects of Nf1 inactivation on in vivo hematopoiesis.
Volume: 108
Issue: 5
Pages: 709-15
Publication
First Author: Kim A
Year: 2007
Journal: Blood
Title: Beta common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice.
Volume: 109
Issue: 4
Pages: 1687-91
Publication
First Author: Mayes DA
Year: 2013
Journal: Cell Rep
Title: Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature.
Volume: 4
Issue: 6
Pages: 1197-212
Publication
First Author: López-Juárez A
Year: 2017
Journal: Cell Rep
Title: Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior.
Volume: 19
Issue: 3
Pages: 545-557
Publication
First Author: Gitler AD
Year: 2003
Journal: Nat Genet
Title: Nf1 has an essential role in endothelial cells.
Volume: 33
Issue: 1
Pages: 75-9
Publication
First Author: Xu J
Year: 2007
Journal: Circulation
Title: NF1 regulates a Ras-dependent vascular smooth muscle proliferative injury response.
Volume: 116
Issue: 19
Pages: 2148-56
Publication
First Author: Wang Y
Year: 2005
Journal: J Neurophysiol
Title: Sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability.
Volume: 94
Issue: 6
Pages: 3670-6
Publication
First Author: Chang T
Year: 2013
Journal: J Clin Invest
Title: Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.
Volume: 123
Issue: 1
Pages: 335-9
Publication
First Author: Klesse LJ
Year: 1998
Journal: J Neurosci
Title: p21 ras and phosphatidylinositol-3 kinase are required for survival of wild-type and NF1 mutant sensory neurons.
Volume: 18
Issue: 24
Pages: 10420-8
Publication
First Author: Kobus K
Year: 2015
Journal: PLoS One
Title: Double NF1 inactivation affects adrenocortical function in NF1Prx1 mice and a human patient.
Volume: 10
Issue: 3
Pages: e0119030
Publication
First Author: Shih YT
Year: 2020
Journal: Cell Rep
Title: Vcp Overexpression and Leucine Supplementation Increase Protein Synthesis and Improve Fear Memory and Social Interaction of Nf1 Mutant Mice.
Volume: 31
Issue: 13
Pages: 107835
Publication
First Author: Dai C
Year: 2012
Journal: J Clin Invest
Title: Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.
Volume: 122
Issue: 10
Pages: 3742-54
Publication  
First Author: Baht GS
Year: 2017
Journal: Bone
Title: Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair.
Volume: 98
Pages: 31-36
Publication
First Author: Zhang P
Year: 2018
Journal: J Clin Invest
Title: Chromatin regulator Asxl1 loss and Nf1 haploinsufficiency cooperate to accelerate myeloid malignancy.
Volume: 128
Issue: 12
Pages: 5383-5398
Publication
First Author: Zhu Y
Year: 2001
Journal: Genes Dev
Title: Ablation of NF1 function in neurons induces abnormal development of cerebral cortex and reactive gliosis in the brain.
Volume: 15
Issue: 7
Pages: 859-76
Publication
First Author: Ismat FA
Year: 2006
Journal: J Clin Invest
Title: The neurofibromin GAP-related domain rescues endothelial but not neural crest development in Nf1 mice.
Volume: 116
Issue: 9
Pages: 2378-84
Publication
First Author: Le DT
Year: 2004
Journal: Blood
Title: Somatic inactivation of Nf1 in hematopoietic cells results in a progressive myeloproliferative disorder.
Volume: 103
Issue: 11
Pages: 4243-50
Publication
First Author: de Bruin EC
Year: 2014
Journal: Cancer Discov
Title: Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer.
Volume: 4
Issue: 5
Pages: 606-19
Publication
First Author: Mayes DA
Year: 2011
Journal: Cancer Res
Title: Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation.
Volume: 71
Issue: 13
Pages: 4675-85
Publication
First Author: Cutts BA
Year: 2009
Journal: Blood
Title: Nf1 deficiency cooperates with oncogenic K-RAS to induce acute myeloid leukemia in mice.
Volume: 114
Issue: 17
Pages: 3629-32
Publication
First Author: Powers JF
Year: 2007
Journal: Neuroscience
Title: Pheochromocytomas in Nf1 knockout mice express a neural progenitor gene expression profile.
Volume: 147
Issue: 4
Pages: 928-37
Publication
First Author: Koenigsmann J
Year: 2009
Journal: Blood
Title: Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias.
Volume: 113
Issue: 19
Pages: 4690-701
Publication
First Author: Hawes JJ
Year: 2007
Journal: Neurogenetics
Title: Nf1 expression is dependent on strain background: implications for tumor suppressor haploinsufficiency studies.
Volume: 8
Issue: 2
Pages: 121-30
Publication
First Author: Ribeiro S
Year: 2013
Journal: Cell Rep
Title: Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve.
Volume: 5
Issue: 1
Pages: 126-36
Publication
First Author: Anastasaki C
Year: 2020
Journal: Stem Cell Reports
Title: Human iPSC-Derived Neurons and Cerebral Organoids Establish Differential Effects of Germline NF1 Gene Mutations.
Volume: 14
Issue: 4
Pages: 541-550
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640519
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1303279
Age: embryonic day 11.5
Image: 11.5
Note: Nf1 expression was seen in the limb mesenchyme.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1640520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:1303279
Age: embryonic day 12.5
Image: 12.5
Note: Nf1 expression was seen in the limb mesenchyme.
Detected: true
Specimen Num: 3
Publication
First Author: Xie K
Year: 2016
Journal: Curr Biol
Title: NF1 Is a Direct G Protein Effector Essential for Opioid Signaling to Ras in the Striatum.
Volume: 26
Issue: 22
Pages: 2992-3003
Publication
First Author: Molosh AI
Year: 2014
Journal: Nat Neurosci
Title: Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase.
Volume: 17
Issue: 11
Pages: 1583-90
Publication
First Author: Wu J
Year: 2008
Journal: Cancer Cell
Title: Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.
Volume: 13
Issue: 2
Pages: 105-16
Publication
First Author: Zhu Y
Year: 2005
Journal: Development
Title: Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
Volume: 132
Issue: 24
Pages: 5577-88
Publication
First Author: Choi G
Year: 2012
Journal: Cancer Res
Title: Genetically mediated Nf1 loss in mice promotes diverse radiation-induced tumors modeling second malignant neoplasms.
Volume: 72
Issue: 24
Pages: 6425-34
Publication
First Author: Nakamura JL
Year: 2011
Journal: Cancer Res
Title: Dose-dependent effects of focal fractionated irradiation on secondary malignant neoplasms in Nf1 mutant mice.
Volume: 71
Issue: 1
Pages: 106-15
Publication
First Author: Li K
Year: 2016
Journal: Dis Model Mech
Title: Mice with missense and nonsense NF1 mutations display divergent phenotypes compared with human neurofibromatosis type I.
Volume: 9
Issue: 7
Pages: 759-67
Publication
First Author: El Khassawna T
Year: 2012
Journal: Bone
Title: Deterioration of fracture healing in the mouse model of NF1 long bone dysplasia.
Volume: 51
Issue: 4
Pages: 651-60
Publication
First Author: Wang W
Year: 2011
Journal: Hum Mol Genet
Title: Mice lacking Nf1 in osteochondroprogenitor cells display skeletal dysplasia similar to patients with neurofibromatosis type I.
Volume: 20
Issue: 20
Pages: 3910-24
Publication
First Author: Wang W
Year: 2010
Journal: J Bone Miner Res
Title: Local low-dose lovastatin delivery improves the bone-healing defect caused by Nf1 loss of function in osteoblasts.
Volume: 25
Issue: 7
Pages: 1658-67
Publication
First Author: Summers MA
Year: 2017
Journal: Int J Dev Biol
Title: Limitations of the Pax7-creERT2 transgene for driving deletion of Nf1 in adult mouse muscle.
Volume: 61
Issue: 8-9
Pages: 531-536
Publication  
First Author: Shofty B
Year: 2019
Journal: Neurobiol Dis
Title: Autism-associated Nf1 deficiency disrupts corticocortical and corticostriatal functional connectivity in human and mouse.
Volume: 130
Pages: 104479
Publication
First Author: Wehrle-Haller B
Year: 2001
Journal: Dev Biol
Title: Analysis of melanocyte precursors in Nf1 mutants reveals that MGF/KIT signaling promotes directed cell migration independent of its function in cell survival.
Volume: 232
Issue: 2
Pages: 471-83
Publication
First Author: Baek ST
Year: 2012
Journal: Development
Title: Nf1 limits epicardial derivative expansion by regulating epithelial to mesenchymal transition and proliferation.
Volume: 139
Issue: 11
Pages: 2040-9
Publication
First Author: Zhu Y
Year: 2005
Journal: Cancer Cell
Title: Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.
Volume: 8
Issue: 2
Pages: 119-30
Publication
First Author: Joseph NM
Year: 2008
Journal: Cancer Cell
Title: The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells.
Volume: 13
Issue: 2
Pages: 129-40
Publication
First Author: Dodd RD
Year: 2013
Journal: Mol Cancer Ther
Title: NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition.
Volume: 12
Issue: 9
Pages: 1906-17
Publication
First Author: Romero MI
Year: 2007
Journal: J Neurosci
Title: Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury.
Volume: 27
Issue: 8
Pages: 2124-34
Publication
First Author: Gitler AD
Year: 2004
Journal: Pediatr Res
Title: Tie2-Cre-induced inactivation of a conditional mutant Nf1 allele in mouse results in a myeloproliferative disorder that models juvenile myelomonocytic leukemia.
Volume: 55
Issue: 4
Pages: 581-4
Publication
First Author: Parrinello S
Year: 2008
Journal: Genes Dev
Title: NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F.
Volume: 22
Issue: 23
Pages: 3335-48
Publication
First Author: Tan M
Year: 2011
Journal: Dev Cell
Title: SAG/RBX2/ROC2 E3 ubiquitin ligase is essential for vascular and neural development by targeting NF1 for degradation.
Volume: 21
Issue: 6
Pages: 1062-76
Publication
First Author: Sanchez-Ortiz E
Year: 2014
Journal: Genes Dev
Title: NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development.
Volume: 28
Issue: 21
Pages: 2407-20
Publication
First Author: Mangues R
Year: 1998
Journal: Oncogene
Title: NF1 inactivation cooperates with N-ras in in vivo lymphogenesis activating Erk by a mechanism independent of its Ras-GTPase accelerating activity.
Volume: 17
Issue: 13
Pages: 1705-16
Publication
First Author: Cho BC
Year: 1995
Journal: J Virol
Title: Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas.
Volume: 69
Issue: 11
Pages: 7138-46
Publication
First Author: Hiatt K
Year: 2004
Journal: Am J Pathol
Title: Loss of the nf1 tumor suppressor gene decreases fas antigen expression in myeloid cells.
Volume: 164
Issue: 4
Pages: 1471-9
Publication
First Author: Stansfield BK
Year: 2013
Journal: Hum Mol Genet
Title: Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway.
Volume: 22
Issue: 5
Pages: 977-88
Publication
First Author: Ingram DA
Year: 2002
Journal: Blood
Title: Lymphoproliferative defects in mice lacking the expression of neurofibromin: functional and biochemical consequences of Nf1 deficiency in T-cell development and function.
Volume: 100
Issue: 10
Pages: 3656-62
Publication
First Author: Hingtgen CM
Year: 2006
Journal: Neuroscience
Title: Stimulus-evoked release of neuropeptides is enhanced in sensory neurons from mice with a heterozygous mutation of the Nf1 gene.
Volume: 137
Issue: 2
Pages: 637-45
Publication
First Author: Kuorilehto T
Year: 2004
Journal: J Bone Miner Res
Title: NF1 tumor suppressor protein and mRNA in skeletal tissues of developing and adult normal mouse and NF1-deficient embryos.
Volume: 19
Issue: 6
Pages: 983-9
Publication
First Author: Jenne DE
Year: 2003
Journal: Genes Chromosomes Cancer
Title: Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse.
Volume: 37
Issue: 2
Pages: 111-20
Publication
First Author: Reilly KM
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Susceptibility to astrocytoma in mice mutant for Nf1 and Trp53 is linked to chromosome 11 and subject to epigenetic effects.
Volume: 101
Issue: 35
Pages: 13008-13
Publication  
First Author: Lepoutre-Lussey C
Year: 2016
Journal: Mol Cell Endocrinol
Title: From Nf1 to Sdhb knockout: Successes and failures in the quest for animal models of pheochromocytoma.
Volume: 421
Pages: 40-8
Publication
First Author: Elefteriou F
Year: 2006
Journal: Cell Metab
Title: ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.
Volume: 4
Issue: 6
Pages: 441-51
Publication
First Author: Ingram DA
Year: 2000
Journal: J Exp Med
Title: Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo.
Volume: 191
Issue: 1
Pages: 181-8
Publication
First Author: Repunte-Canonigo V
Year: 2015
Journal: Biol Psychiatry
Title: Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans.
Volume: 77
Issue: 10
Pages: 870-879
Publication
First Author: Largaespada DA
Year: 1995
Journal: J Virol
Title: Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels.
Volume: 69
Issue: 8
Pages: 5095-102
Publication
First Author: Rice FL
Year: 2019
Journal: PLoS One
Title: The evolution and multi-molecular properties of NF1 cutaneous neurofibromas originating from C-fiber sensory endings and terminal Schwann cells at normal sites of sensory terminations in the skin.
Volume: 14
Issue: 5
Pages: e0216527
Publication
First Author: Keng VW
Year: 2012
Journal: Cancer Res
Title: PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve sheath tumors.
Volume: 72
Issue: 13
Pages: 3405-13
GXD Expression
Probe: MGI:1303255
Assay Type: RNA in situ
Annotation Date: 1998-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1669619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:1303279
Age: embryonic day 11.5
Image: 11.5
Note: Nf1 expression was seen beginning at E11.5 in endocardial cushions in the AV region and in the outflow tract.
Detected: true
Specimen Num: 2
Publication
First Author: Pan Y
Year: 2018
Journal: Genes Dev
Title: Athymic mice reveal a requirement for T-cell-microglia interactions in establishing a microenvironment supportive of Nf1 low-grade glioma growth.
Volume: 32
Issue: 7-8
Pages: 491-496
Publication
First Author: Radomska KJ
Year: 2019
Journal: Cancer Discov
Title: Cellular Origin, Tumor Progression, and Pathogenic Mechanisms of Cutaneous Neurofibromas Revealed by Mice with Nf1 Knockout in Boundary Cap Cells.
Volume: 9
Issue: 1
Pages: 130-147
Publication
First Author: Tong J
Year: 2002
Journal: Nat Neurosci
Title: Neurofibromin regulates G protein-stimulated adenylyl cyclase activity.
Volume: 5
Issue: 2
Pages: 95-6
Publication
First Author: Vogel KS
Year: 1995
Journal: Cell
Title: Loss of neurofibromin results in neurotrophin-independent survival of embryonic sensory and sympathetic neurons.
Volume: 82
Issue: 5
Pages: 733-42
Publication
First Author: Brannan CI
Year: 1994
Journal: Genes Dev
Title: Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues.
Volume: 8
Issue: 9
Pages: 1019-29
Publication
First Author: Xu Y
Year: 2002
Journal: J Neurosci
Title: Gene-targeted deletion of neurofibromin enhances the expression of a transient outward K+ current in Schwann cells: a protein kinase A-mediated mechanism.
Volume: 22
Issue: 21
Pages: 9194-202
Publication
First Author: Atit RP
Year: 2000
Journal: J Invest Dermatol
Title: The neurofibromatosis type 1 (Nf1) tumor suppressor is a modifier of carcinogen-induced pigmentation and papilloma formation in C57BL/6 mice.
Volume: 114
Issue: 6
Pages: 1093-100
Publication  
First Author: Kallarackal AJ
Year: 2013
Journal: Behav Brain Res
Title: The effect of apamin, a small conductance calcium activated potassium (SK) channel blocker, on a mouse model of neurofibromatosis 1.
Volume: 237
Pages: 71-5