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Search results 1 to 100 out of 554 for Nf2

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Hits by Strain

Type Details Score
Gene
4771 | NF2
Type: gene
Organism: human
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Gene
779815 | nf2
Type: gene
Organism: frog, western clawed
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Gene
25744 | Nf2
Type: gene
Organism: rat
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Gene
458744 | NF2
Type: gene
Organism: chimpanzee
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Gene
477535 | NF2
Type: gene
Organism: dog, domestic
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Gene
540479 | NF2
Type: gene
Organism: cattle
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Gene
395158 | NF2
Type: gene
Organism: chicken
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Gene
714945 | NF2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:97307 | Nf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
29712669 | J:263981
 
First Author: Benhamouche-Trouillet S
Year: 2018
Journal: Development
Title: Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis.
Volume: 145
Issue: 9
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Publication
23045274 | J:203242
First Author: Peyre M
Year: 2013
Journal: Oncogene
Title: Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation.
Volume: 32
Issue: 36
Pages: 4264-72
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Protein
Q62207
Organism: Mus musculus/domesticus
Length: 11  
Fragment?: true
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Publication
12000789 | J:76478
First Author: Kalamarides M
Year: 2002
Journal: Genes Dev
Title: Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse.
Volume: 16
Issue: 9
Pages: 1060-5
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Publication
23791728 | J:199463
First Author: Cockburn K
Year: 2013
Journal: Curr Biol
Title: The Hippo pathway member Nf2 is required for inner cell mass specification.
Volume: 23
Issue: 13
Pages: 1195-201
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Publication
27467574 | J:252456
First Author: Schulz A
Year: 2016
Journal: PLoS One
Title: Neuron-Specific Deletion of the Nf2 Tumor Suppressor Impairs Functional Nerve Regeneration.
Volume: 11
Issue: 7
Pages: e0159718
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Publication
17360635 | J:125901
First Author: McLaughlin ME
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The Nf2 tumor suppressor regulates cell-cell adhesion during tissue fusion.
Volume: 104
Issue: 9
Pages: 3261-6
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Publication
27402866 | J:250946
First Author: Matsuda T
Year: 2016
Journal: Circ Res
Title: NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the Heart.
Volume: 119
Issue: 5
Pages: 596-606
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Publication
15221010 | J:92413
First Author: Robanus-Maandag E
Year: 2004
Journal: Oncogene
Title: Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin.
Volume: 23
Issue: 39
Pages: 6541-7
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Publication
17924978 | J:131179
First Author: Kalamarides M
Year: 2008
Journal: Brain Pathol
Title: Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations.
Volume: 18
Issue: 1
Pages: 62-70
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Publication
12695331 | J:83082
First Author: Lallemand D
Year: 2003
Journal: Genes Dev
Title: NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions.
Volume: 17
Issue: 9
Pages: 1090-100
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Publication
27480037 | J:241275
 
First Author: Reginensi A
Year: 2016
Journal: Nat Commun
Title: A critical role for NF2 and the Hippo pathway in branching morphogenesis.
Volume: 7
Pages: 12309
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Publication
10887156 | J:63264
First Author: Giovannini M
Year: 2000
Journal: Genes Dev
Title: Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.
Volume: 14
Issue: 13
Pages: 1617-30
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Publication
27818180 | J:310023
First Author: Shi Y
Year: 2016
Journal: Dev Cell
Title: Rac1-Mediated DNA Damage and Inflammation Promote Nf2 Tumorigenesis but Also Limit Cell-Cycle Progression.
Volume: 39
Issue: 4
Pages: 452-465
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Publication
12802287 | J:83974
First Author: Fleury-Feith J
Year: 2003
Journal: Oncogene
Title: Hemizygosity of Nf2 is associated with increased susceptibility to asbestos-induced peritoneal tumours.
Volume: 22
Issue: 24
Pages: 3799-805
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Publication
29408605 | J:259477
 
First Author: Truong K
Year: 2018
Journal: Neuroscience
Title: Nf2 Mutation in Schwann Cells Delays Functional Neural Recovery Following Injury.
Volume: 374
Pages: 205-213
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Publication
21074722 | J:166833
First Author: Gladden AB
Year: 2010
Journal: Dev Cell
Title: The NF2 tumor suppressor, Merlin, regulates epidermal development through the establishment of a junctional polarity complex.
Volume: 19
Issue: 5
Pages: 727-39
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Publication
28824165 | J:251581
First Author: Vitte J
Year: 2017
Journal: Nat Commun
Title: Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development.
Volume: 8
Issue: 1
Pages: 300
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Publication
23045281 | J:199975
First Author: Manchanda PK
Year: 2013
Journal: Oncogene
Title: Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumors.
Volume: 32
Issue: 30
Pages: 3491-9
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Publication
29249622 | J:253963
First Author: Moon KH
Year: 2018
Journal: Dev Cell
Title: Differential Expression of NF2 in Neuroepithelial Compartments Is Necessary for Mammalian Eye Development.
Volume: 44
Issue: 1
Pages: 13-28.e3
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Publication
10215625 | J:54466
First Author: Giovannini M
Year: 1999
Journal: Genes Dev
Title: Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein.
Volume: 13
Issue: 8
Pages: 978-86
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Publication
32451369 | J:289356
First Author: Park J
Year: 2020
Journal: Mol Cells
Title: WWC1 and NF2 Prevent the Development of Intrahepatic Cholangiocarcinoma by Regulating YAP/TAZ Activity through LATS in Mice.
Volume: 43
Issue: 5
Pages: 491-499
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Publication
26359368 | J:231492
First Author: Garcia-Rendueles ME
Year: 2015
Journal: Cancer Discov
Title: NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition.
Volume: 5
Issue: 11
Pages: 1178-93
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Publication
8012352 | J:17367
First Author: Haase VH
Year: 1994
Journal: Hum Mol Genet
Title: The murine NF2 homologue encodes a highly conserved merlin protein with alternative forms.
Volume: 3
Issue: 3
Pages: 407-11
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Publication
33075808 | J:322987
First Author: Sun WR
Year: 2020
Journal: Hum Mol Genet
Title: Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.
Volume: 29
Issue: 20
Pages: 3373-3387
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Publication
9171370 | J:40596
First Author: McClatchey AI
Year: 1997
Journal: Genes Dev
Title: The Nf2 tumor suppressor gene product is essential for extraembryonic development immediately prior to gastrulation.
Volume: 11
Issue: 10
Pages: 1253-65
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Publication
25336744 | J:217604
First Author: Lavado A
Year: 2014
Journal: Development
Title: The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap.
Volume: 141
Issue: 21
Pages: 4182-93
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Publication
23863479 | J:199301
First Author: Lavado A
Year: 2013
Journal: Development
Title: Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators.
Volume: 140
Issue: 16
Pages: 3323-34
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Publication
14580336 | J:86235
First Author: Kissil JL
Year: 2003
Journal: Mol Cell
Title: Merlin, the product of the Nf2 tumor suppressor gene, is an inhibitor of the p21-activated kinase, Pak1.
Volume: 12
Issue: 4
Pages: 841-9
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Publication
9553042 | J:47282
First Author: McClatchey AI
Year: 1998
Journal: Genes Dev
Title: Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors.
Volume: 12
Issue: 8
Pages: 1121-33
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Publication
26554010 | J:228064
First Author: Gao X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model.
Volume: 112
Issue: 47
Pages: 14676-81
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Publication
15467741 | J:94716
First Author: Wiederhold T
Year: 2004
Journal: Oncogene
Title: Magicin, a novel cytoskeletal protein associates with the NF2 tumor suppressor merlin and Grb2.
Volume: 23
Issue: 54
Pages: 8815-25
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Publication
26418719 | J:316142
First Author: Peyre M
Year: 2015
Journal: Oncotarget
Title: PDGF activation in PGDS-positive arachnoid cells induces meningioma formation in mice promoting tumor progression in combination with Nf2 and Cdkn2ab loss.
Volume: 6
Issue: 32
Pages: 32713-22
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Publication
15797715 | J:96960
First Author: Grönholm M
Year: 2005
Journal: Mol Cell Neurosci
Title: Characterization of the NF2 protein merlin and the ERM protein ezrin in human, rat, and mouse central nervous system.
Volume: 28
Issue: 4
Pages: 683-93
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Publication
31151962 | J:278954
First Author: Kukuyan AM
Year: 2019
Journal: Cancer Res
Title: Inactivation of Bap1 Cooperates with Losses of Nf2 and Cdkn2a to Drive the Development of Pleural Malignant Mesothelioma in Conditional Mouse Models.
Volume: 79
Issue: 16
Pages: 4113-4123
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Publication
34264955 | J:308067
First Author: Chang LS
Year: 2021
Journal: PLoS One
Title: Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.
Volume: 16
Issue: 7
Pages: e0252048
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Publication
24817309 | J:216255
First Author: Garcia C
Year: 2014
Journal: PLoS One
Title: Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2-dependent manner.
Volume: 9
Issue: 5
Pages: e97320
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Publication
19103750 | J:145725
First Author: Houshmandi SS
Year: 2009
Journal: Mol Cell Biol
Title: The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner.
Volume: 29
Issue: 6
Pages: 1472-86
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Publication
29416648 | J:309215
First Author: Wahle BM
Year: 2018
Journal: Oncotarget
Title: Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2.
Volume: 9
Issue: 1
Pages: 718-725
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Publication
24581491 | J:211315
First Author: Mori M
Year: 2014
Journal: Cell
Title: Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer.
Volume: 156
Issue: 5
Pages: 893-906
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Publication
26985001 | J:236337
First Author: Abbassi L
Year: 2016
Journal: Biol Reprod
Title: Multiple Mechanisms Cooperate to Constitutively Exclude the Transcriptional Co-Activator YAP from the Nucleus During Murine Oogenesis.
Volume: 94
Issue: 5
Pages: 102
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Protein
Q99K59
Organism: Mus musculus/domesticus
Length: 353  
Fragment?: false
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Publication
23455610 | J:197562
First Author: Schulz A
Year: 2013
Journal: Nat Neurosci
Title: Merlin isoform 2 in neurofibromatosis type 2-associated polyneuropathy.
Volume: 16
Issue: 4
Pages: 426-33
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Publication
26057084 | J:227436
 
First Author: Ahmad I
Year: 2015
Journal: Neurobiol Dis
Title: Merlin status regulates p75(NTR) expression and apoptotic signaling in Schwann cells following nerve injury.
Volume: 82
Pages: 114-122
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Publication
25113746 | J:216420
First Author: Gehlhausen JR
Year: 2015
Journal: Hum Mol Genet
Title: A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation.
Volume: 24
Issue: 1
Pages: 1-8
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Publication
19029950 | J:316874
First Author: Lallemand D
Year: 2009
Journal: Oncogene
Title: Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomas.
Volume: 28
Issue: 6
Pages: 854-65
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Publication
20181838 | J:161172
First Author: Wiley LA
Year: 2010
Journal: Invest Ophthalmol Vis Sci
Title: The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens.
Volume: 51
Issue: 7
Pages: 3611-8
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Publication
31165301 | J:347385
First Author: Toledo A
Year: 2019
Journal: Brain Struct Funct
Title: Merlin modulates process outgrowth and synaptogenesis in the cerebellum.
Volume: 224
Issue: 6
Pages: 2121-2142
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Publication
18923024 | J:141091
First Author: Denisenko N
Year: 2008
Journal: J Neurosci
Title: Tumor suppressor schwannomin/merlin is critical for the organization of Schwann cell contacts in peripheral nerves.
Volume: 28
Issue: 42
Pages: 10472-81
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Publication
34075397 | J:308853
     
First Author: Hawley E
Year: 2021
Journal: Hum Mol Genet
Title: PAK1 inhibition reduces tumor size and extends the lifespan of mice in a genetically engineered mouse model of Neurofibromatosis Type 2 (NF2).
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Publication
37174657 | J:335633
 
First Author: Gerardo-Ramírez M
Year: 2023
Journal: Cells
Title: Deletion of Cd44 Inhibits Metastasis Formation of Liver Cancer in Nf2-Mutant Mice.
Volume: 12
Issue: 9
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Publication
20675406 | J:163257
First Author: Benhamouche S
Year: 2010
Journal: Genes Dev
Title: Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver.
Volume: 24
Issue: 16
Pages: 1718-30
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Publication
21481793 | J:170978
First Author: Yi C
Year: 2011
Journal: Cancer Cell
Title: A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.
Volume: 19
Issue: 4
Pages: 527-40
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Publication
32271879 | J:289392
 
First Author: Badhai J
Year: 2020
Journal: J Exp Med
Title: Combined deletion of Bap1, Nf2, and Cdkn2ab causes rapid onset of malignant mesothelioma in mice.
Volume: 217
Issue: 6
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Publication
18682243 | J:149793
First Author: Larsson J
Year: 2008
Journal: Cell Stem Cell
Title: Nf2/merlin regulates hematopoietic stem cell behavior by altering microenvironmental architecture.
Volume: 3
Issue: 2
Pages: 221-7
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Publication
19487675 | J:150071
First Author: Morris ZS
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma.
Volume: 106
Issue: 24
Pages: 9767-72
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Publication
20643348 | J:162628
First Author: Zhang N
Year: 2010
Journal: Dev Cell
Title: The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals.
Volume: 19
Issue: 1
Pages: 27-38
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Publication
21242963 | J:173718
First Author: Kalamarides M
Year: 2011
Journal: Oncogene
Title: Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes.
Volume: 30
Issue: 20
Pages: 2333-44
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Publication
25433207 | J:218609
First Author: Serinagaoglu Y
Year: 2015
Journal: Dev Biol
Title: Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development.
Volume: 398
Issue: 1
Pages: 97-109
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Publication
12558984 | J:126709
First Author: Denisenko-Nehrbass N
Year: 2003
Journal: J Neurochem
Title: Association of Caspr/paranodin with tumour suppressor schwannomin/merlin and beta1 integrin in the central nervous system.
Volume: 84
Issue: 2
Pages: 209-21
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Publication
23563179 | J:212373
First Author: Bossuyt W
Year: 2014
Journal: Oncogene
Title: An evolutionary shift in the regulation of the Hippo pathway between mice and flies.
Volume: 33
Issue: 10
Pages: 1218-28
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Publication
28137778 | J:246506
First Author: Mindos T
Year: 2017
Journal: J Cell Biol
Title: Merlin controls the repair capacity of Schwann cells after injury by regulating Hippo/YAP activity.
Volume: 216
Issue: 2
Pages: 495-510
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7981675 | J:19215
First Author: Huynh DP
Year: 1994
Journal: Hum Mol Genet
Title: Alternative transcripts in the mouse neurofibromatosis type 2 (NF2) gene are conserved and code for schwannomins with distinct C-terminal domains.
Volume: 3
Issue: 7
Pages: 1075-9
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Publication
22482125 | J:186214
First Author: Li W
Year: 2012
Journal: EMBO Rep
Title: Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus.
Volume: 13
Issue: 3
Pages: 204-15
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Publication
8088840 | J:18475
First Author: Claudio JO
Year: 1994
Journal: Genomics
Title: The mouse neurofibromatosis type 2 gene maps to chromosome 11.
Volume: 21
Issue: 2
Pages: 437-9
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Publication
34433060 | J:316925
First Author: Wang Y
Year: 2021
Journal: Cell Rep
Title: Stabilization of Motin family proteins in NF2-deficient cells prevents full activation of YAP/TAZ and rapid tumorigenesis.
Volume: 36
Issue: 8
Pages: 109596
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8547603 | J:31660
First Author: Claudio JO
Year: 1995
Journal: Neuroreport
Title: Widespread but cell type-specific expression of the mouse neurofibromatosis type 2 gene.
Volume: 6
Issue: 14
Pages: 1942-6
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12082543 | J:77141
First Author: Gutmann DH
Year: 2002
Journal: Neoplasia
Title: Mouse models of neurofibromatosis 1 and 2.
Volume: 4
Issue: 4
Pages: 279-90
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Publication
33414453 | J:327679
First Author: Kim JE
Year: 2021
Journal: Cell Death Dis
Title: PLPP/CIN-mediated NF2-serine 10 dephosphorylation regulates F-actin stability and Mdm2 degradation in an activity-dependent manner.
Volume: 12
Issue: 1
Pages: 37
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Publication
17272307 | J:122906
First Author: Andujar P
Year: 2007
Journal: Carcinogenesis
Title: Clinico-pathological features and somatic gene alterations in refractory ceramic fibre-induced murine mesothelioma reveal mineral fibre-induced mesothelioma identities.
Volume: 28
Issue: 7
Pages: 1599-605
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Publication
16319530 | J:107034
First Author: Lecomte C
Year: 2005
Journal: Cell Cycle
Title: Similar tumor suppressor gene alteration profiles in asbestos-induced murine and human mesothelioma.
Volume: 4
Issue: 12
Pages: 1862-9
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Publication
26258444 | J:242785
First Author: Zoch A
Year: 2015
Journal: PLoS One
Title: Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation.
Volume: 10
Issue: 8
Pages: e0129151
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Publication
7506121 | J:16430
First Author: Hara T
Year: 1994
Journal: Cancer Res
Title: Molecular cloning and characterization of alternatively spliced transcripts of the mouse neurofibromatosis 2 gene.
Volume: 54
Issue: 2
Pages: 330-5
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Publication
8162023 | J:16587
First Author: Claudio JO
Year: 1994
Journal: Hum Mol Genet
Title: The mouse homologue of the neurofibromatosis type 2 gene is highly conserved.
Volume: 3
Issue: 1
Pages: 185-90
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Publication
7913580 | J:48351
First Author: MacCollin M
Year: 1994
Journal: Am J Hum Genet
Title: Mutational analysis of patients with neurofibromatosis 2.
Volume: 55
Issue: 2
Pages: 314-20
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8930405 | J:37192
First Author: Huynh DP
Year: 1996
Journal: Cell Growth Differ
Title: Expression of neurofibromatosis 2 transcript and gene product during mouse fetal development.
Volume: 7
Issue: 11
Pages: 1551-61
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Publication
19910496 | J:154738
First Author: Lallemand D
Year: 2009
Journal: J Cell Sci
Title: Tumor-suppression functions of merlin are independent of its role as an organizer of the actin cytoskeleton in Schwann cells.
Volume: 122
Issue: Pt 22
Pages: 4141-9
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Publication
19884346 | J:156414
First Author: Hennigan RF
Year: 2010
Journal: Mol Cell Biol
Title: Fluorescence resonance energy transfer analysis of merlin conformational changes.
Volume: 30
Issue: 1
Pages: 54-67
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Publication
21182951 | J:177969
First Author: Thaxton C
Year: 2011
Journal: Mol Cell Neurosci
Title: Schwannomin/merlin promotes Schwann cell elongation and influences myelin segment length.
Volume: 47
Issue: 1
Pages: 1-9
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Publication
24309211 | J:258490
First Author: Schulz A
Year: 2014
Journal: Brain
Title: Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling.
Volume: 137
Issue: Pt 2
Pages: 420-32
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Publication
18328429 | J:132943
First Author: Jongsma J
Year: 2008
Journal: Cancer Cell
Title: A conditional mouse model for malignant mesothelioma.
Volume: 13
Issue: 3
Pages: 261-71
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Publication
34389715 | J:308948
First Author: Grosso S
Year: 2021
Journal: Nat Commun
Title: The pathogenesis of mesothelioma is driven by a dysregulated translatome.
Volume: 12
Issue: 1
Pages: 4920
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Publication
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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