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Search results 1 to 100 out of 891 for Nfatc1

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Type Details Score
Gene
Type: gene
Organism: Not Specified
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: dog, domestic
Protein
Organism: Mus musculus/domesticus
Length: 42  
Fragment?: true
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Zhou B
Year: 2002
Journal: J Biol Chem
Title: Regulation of the murine Nfatc1 gene by NFATc2.
Volume: 277
Issue: 12
Pages: 10704-11
GXD Expression      
Probe: MGI:6506452
Assay Type: RNA in situ
Annotation Date: 2021-02-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6506464
Age: embryonic day 14.0
Specimen Label: S4 Nfatc1 E14
Specimen Num: 2
GXD Expression    
Probe: MGI:6506452
Assay Type: RNA in situ
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608916
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6506464
Age: embryonic day 10.0
Specimen Label: S4 Nfatc1 E10
Detected: true
Specimen Num: 1
Publication
First Author: Kulkarni RM
Year: 2009
Journal: Mech Dev
Title: NFATc1 regulates lymphatic endothelial development.
Volume: 126
Issue: 5-6
Pages: 350-65
Publication
First Author: Lu SY
Year: 2014
Journal: Exp Cell Res
Title: Mitf regulates osteoclastogenesis by modulating NFATc1 activity.
Volume: 328
Issue: 1
Pages: 32-43
Publication
First Author: Combs MD
Year: 2011
Journal: Development
Title: NFATC1 promotes epicardium-derived cell invasion into myocardium.
Volume: 138
Issue: 9
Pages: 1747-57
Publication
First Author: Greenblatt MB
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: NFATc1 and NFATc2 repress spontaneous osteoarthritis.
Volume: 110
Issue: 49
Pages: 19914-9
Publication
First Author: Song I
Year: 2009
Journal: FEBS Lett
Title: Regulatory mechanism of NFATc1 in RANKL-induced osteoclast activation.
Volume: 583
Issue: 14
Pages: 2435-40
Publication
First Author: Oestreich KJ
Year: 2008
Journal: J Immunol
Title: NFATc1 regulates PD-1 expression upon T cell activation.
Volume: 181
Issue: 7
Pages: 4832-9
Publication
First Author: Hock M
Year: 2013
Journal: J Immunol
Title: NFATc1 induction in peripheral T and B lymphocytes.
Volume: 190
Issue: 5
Pages: 2345-53
Publication
First Author: Pan M
Year: 2007
Journal: J Immunol
Title: Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation.
Volume: 178
Issue: 7
Pages: 4315-21
Publication
First Author: Klein-Hessling S
Year: 2017
Journal: Nat Commun
Title: NFATc1 controls the cytotoxicity of CD8+ T cells.
Volume: 8
Issue: 1
Pages: 511
Publication  
First Author: Patil S
Year: 2021
Journal: Cells
Title: Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.
Volume: 10
Issue: 12
Publication
First Author: Horsley V
Year: 2008
Journal: Cell
Title: NFATc1 balances quiescence and proliferation of skin stem cells.
Volume: 132
Issue: 2
Pages: 299-310
Publication
First Author: Giampaolo S
Year: 2023
Journal: iScience
Title: NFATc1 induction by an intronic enhancer restricts NKT γδ cell formation.
Volume: 26
Issue: 3
Pages: 106234
Publication
First Author: Kuroda Y
Year: 2012
Journal: Mol Cell Biol
Title: Cot kinase promotes Ca2+ oscillation/calcineurin-independent osteoclastogenesis by stabilizing NFATc1 protein.
Volume: 32
Issue: 14
Pages: 2954-63
Publication
First Author: Liu R
Year: 2022
Journal: iScience
Title: Dormant Nfatc1 reporter-marked basal stem/progenitor cells contribute to mammary lobuloalveoli formation.
Volume: 25
Issue: 3
Pages: 103982
Publication
First Author: Nurieva RI
Year: 2007
Journal: J Immunol
Title: A costimulation-initiated signaling pathway regulates NFATc1 transcription in T lymphocytes.
Volume: 179
Issue: 2
Pages: 1096-103
Publication
First Author: Keyes BE
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Nfatc1 orchestrates aging in hair follicle stem cells.
Volume: 110
Issue: 51
Pages: E4950-9
Publication  
First Author: Xiao Y
Year: 2021
Journal: J Exp Med
Title: Lack of NFATc1 SUMOylation prevents autoimmunity and alloreactivity.
Volume: 218
Issue: 1
Publication
First Author: Lee Y
Year: 2009
Journal: J Biol Chem
Title: Negative feedback Inhibition of NFATc1 by DYRK1A regulates bone homeostasis.
Volume: 284
Issue: 48
Pages: 33343-51
Publication
First Author: Combs MD
Year: 2009
Journal: Circ Res
Title: VEGF and RANKL regulation of NFATc1 in heart valve development.
Volume: 105
Issue: 6
Pages: 565-74
Publication
First Author: Wu B
Year: 2011
Journal: Circ Res
Title: Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation.
Volume: 109
Issue: 2
Pages: 183-92
Publication
First Author: Omata Y
Year: 2023
Journal: Sci Rep
Title: Essentiality of Nfatc1 short isoform in osteoclast differentiation and its self-regulation.
Volume: 13
Issue: 1
Pages: 18797
Publication
First Author: Berland R
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Normal B-1a cell development requires B cell-intrinsic NFATc1 activity.
Volume: 100
Issue: 23
Pages: 13459-64
Publication
First Author: Goldstein J
Year: 2015
Journal: Mol Biol Cell
Title: Loss of endogenous Nfatc1 reduces the rate of DMBA/TPA-induced skin tumorigenesis.
Volume: 26
Issue: 20
Pages: 3606-14
Publication
First Author: Reppert S
Year: 2015
Journal: Eur J Immunol
Title: NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis.
Volume: 45
Issue: 5
Pages: 1426-40
Publication
First Author: Peng SL
Year: 2001
Journal: Immunity
Title: NFATc1 and NFATc2 together control both T and B cell activation and differentiation.
Volume: 14
Issue: 1
Pages: 13-20
Publication
First Author: Asagiri M
Year: 2005
Journal: J Exp Med
Title: Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.
Volume: 202
Issue: 9
Pages: 1261-9
Publication  
First Author: Alrefai H
Year: 2016
Journal: Nat Commun
Title: NFATc1 supports imiquimod-induced skin inflammation by suppressing IL-10 synthesis in B cells.
Volume: 7
Pages: 11724
Publication  
First Author: Li X
Year: 2015
Journal: Elife
Title: Nur77 prevents excessive osteoclastogenesis by inducing ubiquitin ligase Cbl-b to mediate NFATc1 self-limitation.
Volume: 4
Pages: e07217
Publication
First Author: Ehlers ML
Year: 2014
Journal: Cell Rep
Title: NFATc1 controls skeletal muscle fiber type and is a negative regulator of MyoD activity.
Volume: 8
Issue: 6
Pages: 1639-1648
Publication
First Author: Yang Y
Year: 2019
Journal: J Biol Chem
Title: STAT3 controls osteoclast differentiation and bone homeostasis by regulating NFATc1 transcription.
Volume: 294
Issue: 42
Pages: 15395-15407
Publication
First Author: Kayama H
Year: 2009
Journal: PLoS Pathog
Title: NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection.
Volume: 5
Issue: 7
Pages: e1000514
Publication
First Author: Yamaguchi N
Year: 2012
Journal: Genes Cells
Title: cIAP1/2 negatively regulate RANKL-induced osteoclastogenesis through the inhibition of NFATc1 expression.
Volume: 17
Issue: 12
Pages: 971-81
Publication  
First Author: Klein-Hessling S
Year: 2016
Journal: Nat Commun
Title: A threshold level of NFATc1 activity facilitates thymocyte differentiation and opposes notch-driven leukaemia development.
Volume: 7
Pages: 11841
Publication
First Author: Pérez-Ortiz JM
Year: 2008
Journal: Eur J Neurosci
Title: Mechanical lesion activates newly identified NFATc1 in primary astrocytes: implication of ATP and purinergic receptors.
Volume: 27
Issue: 9
Pages: 2453-65
Publication
First Author: Zhang J
Year: 2016
Journal: Cell Rep
Title: IκB Kinase ε Is an NFATc1 Kinase that Inhibits T Cell Immune Response.
Volume: 16
Issue: 2
Pages: 405-18
Publication
First Author: Choo MK
Year: 2009
Journal: Bone
Title: NFATc1 mediates HDAC-dependent transcriptional repression of osteocalcin expression during osteoblast differentiation.
Volume: 45
Issue: 3
Pages: 579-89
Publication
First Author: Heim L
Year: 2018
Journal: Cancer Res
Title: NFATc1 Promotes Antitumoral Effector Functions and Memory CD8+ T-cell Differentiation during Non-Small Cell Lung Cancer Development.
Volume: 78
Issue: 13
Pages: 3619-3633
Publication
First Author: Decker CE
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Tmem178 acts in a novel negative feedback loop targeting NFATc1 to regulate bone mass.
Volume: 112
Issue: 51
Pages: 15654-9
Publication
First Author: Zanotti S
Year: 2013
Journal: Endocrinology
Title: Notch suppresses nuclear factor of activated T cells (NFAT) transactivation and Nfatc1 expression in chondrocytes.
Volume: 154
Issue: 2
Pages: 762-72
Publication
First Author: Busch R
Year: 2016
Journal: Eur J Immunol
Title: NFATc1 releases BCL6-dependent repression of CCR2 agonist expression in peritoneal macrophages from Saccharomyces cerevisiae infected mice.
Volume: 46
Issue: 3
Pages: 634-46
Publication  
First Author: Jeong BC
Year: 2017
Journal: Bone
Title: ATF3 modulates calcium signaling in osteoclast differentiation and activity by associating with c-Fos and NFATc1 proteins.
Volume: 95
Pages: 33-40
Publication
First Author: Bhattacharyya S
Year: 2011
Journal: J Exp Med
Title: NFATc1 affects mouse splenic B cell function by controlling the calcineurin--NFAT signaling network.
Volume: 208
Issue: 4
Pages: 823-39
Publication
First Author: Kim K
Year: 2007
Journal: J Immunol
Title: Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor.
Volume: 178
Issue: 9
Pages: 5588-94
Publication
First Author: Aliprantis AO
Year: 2008
Journal: J Clin Invest
Title: NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism.
Volume: 118
Issue: 11
Pages: 3775-89
Publication
First Author: Feng L
Year: 2023
Journal: Glia
Title: Microglial LRRK2-mediated NFATc1 attenuates α-synuclein immunotoxicity in association with CX3CR1-induced migration and the lysosome-initiated degradation.
Volume: 71
Issue: 9
Pages: 2266-2284
Publication
First Author: Yan J
Year: 2013
Journal: PLoS One
Title: OX40-OX40L interaction promotes proliferation and activation of lymphocytes via NFATc1 in ApoE-deficient mice.
Volume: 8
Issue: 4
Pages: e60854
Publication
First Author: Kim SD
Year: 2013
Journal: Biochem Pharmacol
Title: Trapidil, a platelet-derived growth factor antagonist, inhibits osteoclastogenesis by down-regulating NFATc1 and suppresses bone loss in mice.
Volume: 86
Issue: 6
Pages: 782-90
Publication
First Author: Sharma SM
Year: 2007
Journal: J Biol Chem
Title: MITF and PU.1 recruit p38 MAPK and NFATc1 to target genes during osteoclast differentiation.
Volume: 282
Issue: 21
Pages: 15921-9
Publication
First Author: Chen NM
Year: 2015
Journal: Gastroenterology
Title: NFATc1 Links EGFR Signaling to Induction of Sox9 Transcription and Acinar-Ductal Transdifferentiation in the Pancreas.
Volume: 148
Issue: 5
Pages: 1024-1034.e9
Publication  
First Author: Valerio MS
Year: 2014
Journal: Bone
Title: MKP-1 signaling events are required for early osteoclastogenesis in lineage defined progenitor populations by disrupting RANKL-induced NFATc1 nuclear translocation.
Volume: 60
Pages: 16-25
Publication
First Author: Dupays L
Year: 2005
Journal: J Mol Cell Cardiol
Title: Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants.
Volume: 38
Issue: 5
Pages: 787-98
Publication
First Author: Voronov I
Year: 2013
Journal: J Bone Miner Res
Title: The R740S mutation in the V-ATPase a3 subunit increases lysosomal pH, impairs NFATc1 translocation, and decreases in vitro osteoclastogenesis.
Volume: 28
Issue: 1
Pages: 108-18
Publication
First Author: Matsumoto M
Year: 2004
Journal: J Biol Chem
Title: Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1.
Volume: 279
Issue: 44
Pages: 45969-79
Publication
First Author: Lange AW
Year: 2004
Journal: Dev Biol
Title: DSCR1 gene expression is dependent on NFATc1 during cardiac valve formation and colocalizes with anomalous organ development in trisomy 16 mice.
Volume: 266
Issue: 2
Pages: 346-60
Publication
First Author: Lange AW
Year: 2006
Journal: Dev Biol
Title: NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K.
Volume: 292
Issue: 2
Pages: 407-17
Publication
First Author: Munger SJ
Year: 2016
Journal: Dev Biol
Title: Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice.
Volume: 412
Issue: 2
Pages: 173-90
GXD Expression
Probe: MGI:5660390
Assay Type: Immunohistochemistry
Annotation Date: 2015-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1635417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:5660396
Age: embryonic day 10.5
Image: 1A
Note: Expressed in the cardinal vein endothelial cells and lymphatic endothelial cells sprouting from the cardinal vein. Expressed in nuclei, as shown in inset. Nfatc1 and Prox1 were colocalized only in the regions of active lymphatic sprouting.
Specimen Label: 1A
Detected: true
Specimen Num: 1
Publication
First Author: Winslow MM
Year: 2006
Journal: Dev Cell
Title: Calcineurin/NFAT signaling in osteoblasts regulates bone mass.
Volume: 10
Issue: 6
Pages: 771-82
Publication      
First Author: Klein-Hessling S
Year: 2023
Journal: MGI Direct Data Submission
Title: Direct Data Submission of Nfatc1 Allele.
Publication
First Author: Nijenhuis T
Year: 2011
Journal: Am J Pathol
Title: Angiotensin II contributes to podocyte injury by increasing TRPC6 expression via an NFAT-mediated positive feedback signaling pathway.
Volume: 179
Issue: 4
Pages: 1719-32
Publication
First Author: Toomer KA
Year: 2017
Journal: Dev Dyn
Title: A role for primary cilia in aortic valve development and disease.
Volume: 246
Issue: 8
Pages: 625-634
Publication
First Author: Wang Y
Year: 2010
Journal: J Am Soc Nephrol
Title: Activation of NFAT signaling in podocytes causes glomerulosclerosis.
Volume: 21
Issue: 10
Pages: 1657-66
Publication
First Author: Ge X
Year: 2016
Journal: JCI Insight
Title: NFAT restricts osteochondroma formation from entheseal progenitors.
Volume: 1
Issue: 4
Pages: e86254
Publication
First Author: Chuvpilo S
Year: 2002
Journal: Immunity
Title: Autoregulation of NFATc1/A expression facilitates effector T cells to escape from rapid apoptosis.
Volume: 16
Issue: 6
Pages: 881-95
Publication
First Author: Klein M
Year: 2012
Journal: J Immunol
Title: Repression of cyclic adenosine monophosphate upregulation disarms and expands human regulatory T cells.
Volume: 188
Issue: 3
Pages: 1091-7
Publication
First Author: Lee Y
Year: 2013
Journal: Bone
Title: MicroRNA-124 regulates osteoclast differentiation.
Volume: 56
Issue: 2
Pages: 383-9
Publication
First Author: Canté-Barrett K
Year: 2007
Journal: J Immunol
Title: Selective role of NFATc3 in positive selection of thymocytes.
Volume: 179
Issue: 1
Pages: 103-10
Publication
First Author: Lietman SA
Year: 2008
Journal: Biochem Biophys Res Commun
Title: SH3BP2 is an activator of NFAT activity and osteoclastogenesis.
Volume: 371
Issue: 4
Pages: 644-8
Publication
First Author: Rana ZA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Activity-dependent repression of muscle genes by NFAT.
Volume: 105
Issue: 15
Pages: 5921-6
Publication
First Author: Wada H
Year: 2002
Journal: J Cell Biol
Title: Calcineurin-GATA-6 pathway is involved in smooth muscle-specific transcription.
Volume: 156
Issue: 6
Pages: 983-91
Publication
First Author: Fromigué O
Year: 2010
Journal: J Biol Chem
Title: Essential role of nuclear factor of activated T cells (NFAT)-mediated Wnt signaling in osteoblast differentiation induced by strontium ranelate.
Volume: 285
Issue: 33
Pages: 25251-8
Publication
First Author: Maruya M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Vitamin A-dependent transcriptional activation of the nuclear factor of activated T cells c1 (NFATc1) is critical for the development and survival of B1 cells.
Volume: 108
Issue: 2
Pages: 722-7
Publication
First Author: Chen NM
Year: 2017
Journal: Gastroenterology
Title: Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.
Volume: 152
Issue: 6
Pages: 1507-1520.e15
Publication
First Author: Zhang H
Year: 2016
Journal: Circ Res
Title: Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.
Volume: 118
Issue: 12
Pages: 1880-93
Publication
First Author: Agarwal S
Year: 2015
Journal: Dev Biol
Title: BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints.
Volume: 400
Issue: 2
Pages: 202-9
Publication  
First Author: Jiang DS
Year: 2014
Journal: Nat Commun
Title: IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling.
Volume: 5
Pages: 3303
Publication
First Author: Patra AK
Year: 2013
Journal: Nat Immunol
Title: An alternative NFAT-activation pathway mediated by IL-7 is critical for early thymocyte development.
Volume: 14
Issue: 2
Pages: 127-35
Publication
First Author: Wu B
Year: 2023
Journal: J Am Heart Assoc
Title: Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development.
Volume: 12
Issue: 18
Pages: e029683
Publication
First Author: Neugebauer J
Year: 2018
Journal: Hum Mol Genet
Title: Plastin 3 influences bone homeostasis through regulation of osteoclast activity.
Volume: 27
Issue: 24
Pages: 4249-4262
Publication
First Author: Xiong Y
Year: 2013
Journal: Dev Cell
Title: Brg1 governs a positive feedback circuit in the hair follicle for tissue regeneration and repair.
Volume: 25
Issue: 2
Pages: 169-81
Publication  
First Author: George RM
Year: 2023
Journal: Development
Title: Single cell evaluation of endocardial Hand2 gene regulatory networks reveals HAND2-dependent pathways that impact cardiac morphogenesis.
Volume: 150
Issue: 3
Publication
First Author: Yoon SH
Year: 2009
Journal: FEBS Lett
Title: Lyn inhibits osteoclast differentiation by interfering with PLCgamma1-mediated Ca2+ signaling.
Volume: 583
Issue: 7
Pages: 1164-70
Publication
First Author: Sauls K
Year: 2012
Journal: Cardiovasc Res
Title: Developmental basis for filamin-A-associated myxomatous mitral valve disease.
Volume: 96
Issue: 1
Pages: 109-19
Publication
First Author: Fulmer D
Year: 2019
Journal: Circulation
Title: Defects in the Exocyst-Cilia Machinery Cause Bicuspid Aortic Valve Disease and Aortic Stenosis.
Volume: 140
Issue: 16
Pages: 1331-1341
Publication
First Author: Pedigo CE
Year: 2016
Journal: J Clin Invest
Title: Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury.
Volume: 126
Issue: 9
Pages: 3336-50