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Search results 1 to 100 out of 448 for Nfatc2

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
4773 | NFATC2
Type: gene
Organism: human
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Gene
100490186 | nfatc2
Type: gene
Organism: frog, western clawed
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Gene
311658 | Nfatc2
Type: gene
Organism: rat
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Gene
485930 | NFATC2
Type: gene
Organism: dog, domestic
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Gene
469972 | NFATC2
Type: gene
Organism: chimpanzee
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Gene
530401 | NFATC2
Type: gene
Organism: cattle
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Gene
419346 | NFATC2
Type: gene
Organism: chicken
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Gene
710601 | NFATC2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:102463 | Nfatc2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25573264 | J:233351
First Author: Zanotti S
Year: 2015
Journal: J Cell Physiol
Title: Activation of Nfatc2 in osteoblasts causes osteopenia.
Volume: 230
Issue: 7
Pages: 1689-95
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GXD Expression
GXD Expression
   
Probe: MGI:6506453
Assay Type: RNA in situ
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1608916
Pattern: Not Specified
Stage: TS16
Assay Id: MGI:6506465
Age: embryonic day 10.0
Specimen Label: S4 Nfatc2 E10
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6506453
Assay Type: RNA in situ
Annotation Date: 2021-02-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6506465
Age: embryonic day 14.0
Specimen Label: S4 Nfatc2 E14
Detected: true
Specimen Num: 2
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Publication
24507801 | J:319030
First Author: Bonami RH
Year: 2014
Journal: Mol Immunol
Title: NFATc2 (NFAT1) assists BCR-mediated anergy in anti-insulin B cells.
Volume: 62
Issue: 2
Pages: 321-8
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Publication
24248346 | J:203051
First Author: Greenblatt MB
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: NFATc1 and NFATc2 repress spontaneous osteoarthritis.
Volume: 110
Issue: 49
Pages: 19914-9
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Publication
15684054 | J:96502
First Author: Mehta DS
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: NFATc2 and T-bet contribute to T-helper-cell-subset-specific regulation of IL-21 expression.
Volume: 102
Issue: 6
Pages: 2016-21
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Publication
11163226 | J:67221
First Author: Peng SL
Year: 2001
Journal: Immunity
Title: NFATc1 and NFATc2 together control both T and B cell activation and differentiation.
Volume: 14
Issue: 1
Pages: 13-20
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Publication
11740499 | J:109185
First Author: Rengarajan J
Year: 2002
Journal: Nat Immunol
Title: NFATc2 and NFATc3 regulate T(H)2 differentiation and modulate TCR-responsiveness of naïve T(H)cells.
Volume: 3
Issue: 1
Pages: 48-54
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Publication
22738913 | J:191029
First Author: Gerlach K
Year: 2012
Journal: Cancer Res
Title: Transcription factor NFATc2 controls the emergence of colon cancer associated with IL-6-dependent colitis.
Volume: 72
Issue: 17
Pages: 4340-50
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Publication
19318584 | J:147351
First Author: Maxeiner JH
Year: 2009
Journal: Cancer Res
Title: A key regulatory role of the transcription factor NFATc2 in bronchial adenocarcinoma via CD8+ T lymphocytes.
Volume: 69
Issue: 7
Pages: 3069-76
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Publication
18477567 | J:139064
First Author: Bourajjaj M
Year: 2008
Journal: J Biol Chem
Title: NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure.
Volume: 283
Issue: 32
Pages: 22295-303
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Publication
28505967 | J:272736
First Author: Manocha GD
Year: 2017
Journal: J Alzheimers Dis
Title: NFATc2 Modulates Microglial Activation in the AβPP/PS1 Mouse Model of Alzheimer's Disease.
Volume: 58
Issue: 3
Pages: 775-787
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Publication
24945807 | J:218952
First Author: May SL
Year: 2014
Journal: PLoS One
Title: Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis.
Volume: 9
Issue: 6
Pages: e100629
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Publication
18710929 | J:138976
First Author: Weigmann B
Year: 2008
Journal: J Exp Med
Title: The transcription factor NFATc2 controls IL-6-dependent T cell activation in experimental colitis.
Volume: 205
Issue: 9
Pages: 2099-110
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Publication
35773432 | J:333979
First Author: Zhu L
Year: 2022
Journal: Nat Cell Biol
Title: Dapl1 controls NFATc2 activation to regulate CD8(+) T cell exhaustion and responses in chronic infection and cancer.
Volume: 24
Issue: 7
Pages: 1165-1176
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Publication
27935966 | J:237488
First Author: Keller MP
Year: 2016
Journal: PLoS Genet
Title: The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
Volume: 12
Issue: 12
Pages: e1006466
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Publication
12368232 | J:120161
First Author: Caetano MS
Year: 2002
Journal: FASEB J
Title: NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: evidence of its involvement in the control of cyclin gene expression.
Volume: 16
Issue: 14
Pages: 1940-2
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Publication
15657288 | J:95523
First Author: Bopp T
Year: 2005
Journal: J Exp Med
Title: NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4+ T lymphocytes by CD4+ CD25+ regulatory T cells.
Volume: 201
Issue: 2
Pages: 181-7
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Protein
Q6P3F6
Organism: Mus musculus/domesticus
Length: 624  
Fragment?: false
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Publication
14573689 | J:86279
First Author: Erb KJ
Year: 2003
Journal: Infect Immun
Title: Mice deficient in nuclear factor of activated T-cell transcription factor c2 mount increased Th2 responses after infection with Nippostrongylus brasiliensis and decreased Th1 responses after mycobacterial infection.
Volume: 71
Issue: 11
Pages: 6641-7
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Publication
20696888 | J:163688
First Author: Ghosh S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis.
Volume: 107
Issue: 34
Pages: 15169-74
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Publication
11309414 | J:68943
First Author: Horsley V
Year: 2001
Journal: J Cell Biol
Title: Regulation of the growth of multinucleated muscle cells by an NFATC2-dependent pathway.
Volume: 153
Issue: 2
Pages: 329-38
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Publication
16908540 | J:114654
First Author: Yang TT
Year: 2006
Journal: Mol Cell Biol
Title: Role of transcription factor NFAT in glucose and insulin homeostasis.
Volume: 26
Issue: 20
Pages: 7372-87
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Publication
12453415 | J:80577
First Author: Baksh S
Year: 2002
Journal: Mol Cell
Title: NFATc2-mediated repression of cyclin-dependent kinase 4 expression.
Volume: 10
Issue: 5
Pages: 1071-81
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Publication
15814705 | J:98146
First Author: Samanta DN
Year: 2005
Journal: J Immunol
Title: B cell hyperresponsiveness and expansion of mature follicular B cells but not of marginal zone B cells in NFATc2/c3 double-deficient mice.
Volume: 174
Issue: 8
Pages: 4797-802
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Publication
30010214 | J:289229
First Author: Yu J
Year: 2018
Journal: J Cell Biochem
Title: Nuclear factor of activated T cells 2 is required for osteoclast differentiation and function in vitro but not in vivo.
Volume: 119
Issue: 11
Pages: 9334-9345
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Publication
12757709 | J:107688
First Author: Horsley V
Year: 2003
Journal: Cell
Title: IL-4 acts as a myoblast recruitment factor during mammalian muscle growth.
Volume: 113
Issue: 4
Pages: 483-94
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Publication
16275763 | J:118753
First Author: Asagiri M
Year: 2005
Journal: J Exp Med
Title: Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.
Volume: 202
Issue: 9
Pages: 1261-9
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Publication
17986443 | J:130290
First Author: Tan AH
Year: 2008
Journal: J Biol Chem
Title: T helper cell-specific regulation of inducible costimulator expression via distinct mechanisms mediated by T-bet and GATA-3.
Volume: 283
Issue: 1
Pages: 128-36
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Publication
11786533 | J:75448
First Author: Zhou B
Year: 2002
Journal: J Biol Chem
Title: Regulation of the murine Nfatc1 gene by NFATc2.
Volume: 277
Issue: 12
Pages: 10704-11
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Publication
28894104 | J:247562
First Author: Klein-Hessling S
Year: 2017
Journal: Nat Commun
Title: NFATc1 controls the cytotoxicity of CD8+ T cells.
Volume: 8
Issue: 1
Pages: 511
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Publication
19414766 | J:148241
First Author: Becker M
Year: 2009
Journal: J Immunol
Title: Impaired mast cell-driven immune responses in mice lacking the transcription factor NFATc2.
Volume: 182
Issue: 10
Pages: 6136-42
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Publication
32778883 | J:320917
First Author: Rivaud MR
Year: 2020
Journal: Europace
Title: Functional modulation of atrio-ventricular conduction by enhanced late sodium current and calcium-dependent mechanisms in Scn5a1798insD/+ mice.
Volume: 22
Issue: 10
Pages: 1579-1589
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Publication
23509367 | J:195290
First Author: Mikami N
Year: 2013
Journal: J Immunol
Title: Calcitonin gene-related peptide and cyclic adenosine 5'-monophosphate/protein kinase A pathway promote IL-9 production in Th9 differentiation process.
Volume: 190
Issue: 8
Pages: 4046-55
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Publication
14595020 | J:86543
First Author: Berland R
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Normal B-1a cell development requires B cell-intrinsic NFATc1 activity.
Volume: 100
Issue: 23
Pages: 13459-64
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Publication
17082579 | J:140496
First Author: Klein M
Year: 2006
Journal: J Immunol
Title: Specific and redundant roles for NFAT transcription factors in the expression of mast cell-derived cytokines.
Volume: 177
Issue: 10
Pages: 6667-74
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Publication
27158674 | J:290980
First Author: Ge X
Year: 2016
Journal: JCI Insight
Title: NFAT restricts osteochondroma formation from entheseal progenitors.
Volume: 1
Issue: 4
Pages: e86254
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Publication
19752193 | J:154929
First Author: Maitra U
Year: 2009
Journal: Mol Cell Biol
Title: An innate immunity signaling process suppresses macrophage ABCA1 expression through IRAK-1-mediated downregulation of retinoic acid receptor alpha and NFATc2.
Volume: 29
Issue: 22
Pages: 5989-97
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Publication
16880206 | J:116928
First Author: Tan AH
Year: 2006
Journal: J Biol Chem
Title: Regulation of mouse inducible costimulator (ICOS) expression by Fyn-NFATc2 and ERK signaling in T cells.
Volume: 281
Issue: 39
Pages: 28666-78
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Publication
24106272 | J:319029
First Author: Crist SA
Year: 2013
Journal: J Biol Chem
Title: Early growth response-1 (EGR-1) and nuclear factor of activated T cells (NFAT) cooperate to mediate CD40L expression in megakaryocytes and platelets.
Volume: 288
Issue: 47
Pages: 33985-33996
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Publication
24039733 | J:206398
First Author: Nakashima Y
Year: 2013
Journal: PLoS One
Title: Stimulation of osteoclast formation by RANKL requires interferon regulatory factor-4 and is inhibited by simvastatin in a mouse model of bone loss.
Volume: 8
Issue: 9
Pages: e72033
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Publication
17579027 | J:141917
First Author: Canté-Barrett K
Year: 2007
Journal: J Immunol
Title: Selective role of NFATc3 in positive selection of thymocytes.
Volume: 179
Issue: 1
Pages: 103-10
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Publication
24301466 | J:206594
First Author: Daou N
Year: 2013
Journal: Development
Title: A new role for the calcineurin/NFAT pathway in neonatal myosin heavy chain expression via the NFATc2/MyoD complex during mouse myogenesis.
Volume: 140
Issue: 24
Pages: 4914-25
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Protein Coding Gene
MGP_CAROLIEiJ_G0024721 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026894 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026865 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026645 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_102463 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0027350 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026103 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026726 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026745 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027407 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025840 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0026176 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0026162 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025641 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8668213 | J:33570
First Author: Luo C
Year: 1996
Journal: Mol Cell Biol
Title: Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes.
Volume: 16
Issue: 7
Pages: 3955-66
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Publication
11278367 | J:87345
First Author: Plyte S
Year: 2001
Journal: J Biol Chem
Title: Identification and characterization of a novel nuclear factor of activated T-cells-1 isoform expressed in mouse brain.
Volume: 276
Issue: 17
Pages: 14350-8
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Publication
9442388 | J:45252
First Author: Heyer J
Year: 1997
Journal: Immunobiology
Title: Inefficient termination of antigen responses in NF-ATp-deficient mice.
Volume: 198
Issue: 1-3
Pages: 162-9
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Publication
9710223 | J:110686
First Author: Schuh K
Year: 1998
Journal: Eur J Immunol
Title: Retarded thymic involution and massive germinal center formation in NF-ATp-deficient mice.
Volume: 28
Issue: 8
Pages: 2456-66
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Publication
9232447 | J:150931
First Author: Schuh K
Year: 1997
Journal: Immunol Lett
Title: NF-ATp plays a prominent role in the transcriptional induction of Th2-type lymphokines.
Volume: 57
Issue: 1-3
Pages: 171-5
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Publication
10620601 | J:59243
First Author: Ranger AM
Year: 2000
Journal: J Exp Med
Title: The nuclear factor of activated T cells (NFAT) transcription factor NFATp (NFATc2) is a repressor of chondrogenesis.
Volume: 191
Issue: 1
Pages: 9-22
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Publication
19526482 | J:152860
First Author: Wang J
Year: 2009
Journal: J Pathol
Title: Transcription factor Nfat1 deficiency causes osteoarthritis through dysfunction of adult articular chondrocytes.
Volume: 219
Issue: 2
Pages: 163-72
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Publication
22844476 | J:189722
First Author: Via LE
Year: 2012
Journal: PLoS One
Title: The transcription factor NFATp plays a key role in susceptibility to TB in mice.
Volume: 7
Issue: 7
Pages: e41427
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Publication
28972088 | J:250819
First Author: Chae CS
Year: 2017
Journal: J Immunol
Title: NFAT1 Regulates Systemic Autoimmunity through the Modulation of a Dendritic Cell Property.
Volume: 199
Issue: 9
Pages: 3051-3062
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Publication
16849457 | J:137979
First Author: Barrington RA
Year: 2006
Journal: J Immunol
Title: Involvement of NFAT1 in B cell self-tolerance.
Volume: 177
Issue: 3
Pages: 1510-5
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Publication
31555297 | J:282113
 
First Author: Benevides L
Year: 2019
Journal: Front Immunol
Title: NFAT1 Regulates Ly6Chi Monocyte Recruitment to the CNS and Plays an Essential Role in Resistance to Toxoplasma gondii Infection.
Volume: 10
Pages: 2105
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Publication
16237086 | J:119337
First Author: Teixeira LK
Year: 2005
Journal: J Immunol
Title: IFN-gamma production by CD8+ T cells depends on NFAT1 transcription factor and regulates Th differentiation.
Volume: 175
Issue: 9
Pages: 5931-9
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Publication
9430230 | J:111250
First Author: Kiani A
Year: 1997
Journal: Immunity
Title: Down-regulation of IL-4 gene transcription and control of Th2 cell differentiation by a mechanism involving NFAT1.
Volume: 7
Issue: 6
Pages: 849-60
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Publication
9516119 | J:111023
First Author: Viola JP
Year: 1998
Journal: Blood
Title: Regulation of allergic inflammation and eosinophil recruitment in mice lacking the transcription factor NFAT1: role of interleukin-4 (IL-4) and IL-5.
Volume: 91
Issue: 7
Pages: 2223-30
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Publication
18664642 | J:155998
First Author: Fonseca BP
Year: 2009
Journal: Am J Respir Cell Mol Biol
Title: NFAT1 transcription factor regulates pulmonary allergic inflammation and airway responsiveness.
Volume: 40
Issue: 1
Pages: 66-75
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Publication
28630062 | J:326318
 
First Author: Ames RY
Year: 2017
Journal: Infect Immun
Title: The Transcription Factor NFAT1 Participates in the Induction of CD4+ T Cell Functional Exhaustion during Plasmodium yoelii Infection.
Volume: 85
Issue: 9
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Publication
23105117 | J:190673
First Author: Vázquez-Cedeira M
Year: 2012
Journal: J Biol Chem
Title: Human VRK2 (vaccinia-related kinase 2) modulates tumor cell invasion by hyperactivation of NFAT1 and expression of cyclooxygenase-2.
Volume: 287
Issue: 51
Pages: 42739-50
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Publication
7961754 | J:22132
First Author: Ho AM
Year: 1994
Journal: J Biol Chem
Title: Expression of the transcription factor NFATp in a neuronal cell line and in the murine nervous system.
Volume: 269
Issue: 45
Pages: 28181-6
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Publication
15117942 | J:91548
First Author: Terui Y
Year: 2004
Journal: J Biol Chem
Title: Dual role of sumoylation in the nuclear localization and transcriptional activation of NFAT1.
Volume: 279
Issue: 27
Pages: 28257-65
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Publication
10894164 | J:111995
First Author: Agarwal S
Year: 2000
Journal: Immunity
Title: Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo.
Volume: 12
Issue: 6
Pages: 643-52
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Publication
17651692 | J:123484
First Author: Holowachuk EW
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Nuclear factor of activated T cell (NFAT) transcription proteins regulate genes involved in adipocyte metabolism and lipolysis.
Volume: 361
Issue: 2
Pages: 427-32
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Publication
24894426 | J:318202
First Author: Barboza BA
Year: 2014
Journal: Immunobiology
Title: NFAT1 transcription factor in dendritic cells is required to modulate T helper cell differentiation.
Volume: 219
Issue: 9
Pages: 704-12
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Publication
36842570 | J:335708
 
First Author: Jiang F
Year: 2023
Journal: Brain Res
Title: Role of nuclear factor of activated T Cells-1 in Sepsis-induced behavioral deficits in mice.
Volume: 1806
Pages: 148299
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GXD Expression
GXD Expression
   
Probe: MGI:3708310
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610521
Stage: TS21
Assay Id: MGI:3708375
Age: embryonic day 13.5
Image: 7
Specimen Label: E13.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3708310
Assay Type: RT-PCR
Annotation Date: 2007-05-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610524
Stage: TS24
Assay Id: MGI:3708375
Age: embryonic day 16.5
Image: 7
Specimen Label: E16.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1195740
Assay Type: Northern blot
Annotation Date: 2018-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:6118208
Age: embryonic day 7.0
Specimen Label: 7
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1195740
Assay Type: Northern blot
Annotation Date: 2018-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:6118208
Age: embryonic day 11.0
Specimen Label: 11
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1195740
Assay Type: Northern blot
Annotation Date: 2018-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:6118208
Age: embryonic day 15.0
Specimen Label: 15
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:1195740
Assay Type: Northern blot
Annotation Date: 2018-03-01
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:6118208
Age: embryonic day 17.0
Specimen Label: 17
Detected: true
Specimen Num: 4
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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