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Search results 1 to 86 out of 86 for Nhej1

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
79840 | NHEJ1
Type: gene
Organism: human
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Gene
509157 | NHEJ1
Type: gene
Organism: cattle
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Gene
424205 | NHEJ1
Type: gene
Organism: chicken
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Gene
406593 | nhej1
Type: gene
Organism: zebrafish
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Gene
701542 | NHEJ1
Type: gene
Organism: macaque, rhesus
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Gene
100145147 | nhej1
Type: gene
Organism: frog, western clawed
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Gene
363251 | Nhej1
Type: gene
Organism: rat
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Gene
610570 | NHEJ1
Type: gene
Organism: dog, domestic
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Gene
742646 | NHEJ1
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1922820 | Nhej1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CAROLIEiJ_G0014281 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0016169 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1922820 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016560 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015522 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0016015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0016084 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0016035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016607 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027519 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0015087 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16439205 | J:116418
First Author: Ahnesorg P
Year: 2006
Journal: Cell
Title: XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining.
Volume: 124
Issue: 2
Pages: 301-13
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Publication
16439204 | J:116419
First Author: Buck D
Year: 2006
Journal: Cell
Title: Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly.
Volume: 124
Issue: 2
Pages: 287-99
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Publication
25661488 | J:219887
First Author: Liu P
Year: 2015
Journal: Mol Cell
Title: Akt-mediated phosphorylation of XLF impairs non-homologous end-joining DNA repair.
Volume: 57
Issue: 4
Pages: 648-61
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Publication
29950655 | J:267957
First Author: Bhargava R
Year: 2018
Journal: Nat Commun
Title: C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains.
Volume: 9
Issue: 1
Pages: 2484
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Publication
27601633 | J:238354
First Author: Kumar V
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: PAXX and XLF DNA repair factors are functionally redundant in joining DNA breaks in a G1-arrested progenitor B-cell line.
Volume: 113
Issue: 38
Pages: 10619-24
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Publication
22308489 | J:182021
First Author: Oksenych V
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Functional redundancy between repair factor XLF and damage response mediator 53BP1 in V(D)J recombination and DNA repair.
Volume: 109
Issue: 7
Pages: 2455-60
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Publication
22355127 | J:182138
First Author: Liu X
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Overlapping functions between XLF repair protein and 53BP1 DNA damage response factor in end joining and lymphocyte development.
Volume: 109
Issue: 10
Pages: 3903-8
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Publication
32355287 | J:311900
First Author: Liu X
Year: 2020
Journal: Cell Res
Title: ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells.
Volume: 30
Issue: 9
Pages: 732-744
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Publication
31915249 | J:285359
First Author: Musilli S
Year: 2020
Journal: J Biol Chem
Title: An in vivo study of the impact of deficiency in the DNA repair proteins PAXX and XLF on development and maturation of the hemolymphoid system.
Volume: 295
Issue: 8
Pages: 2398-2406
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Publication
19056826 | J:173044
First Author: Riballo E
Year: 2009
Journal: Nucleic Acids Res
Title: XLF-Cernunnos promotes DNA ligase IV-XRCC4 re-adenylation following ligation.
Volume: 37
Issue: 2
Pages: 482-92
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Publication
17360556 | J:120145
First Author: Zha S
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Defective DNA repair and increased genomic instability in Cernunnos-XLF-deficient murine ES cells.
Volume: 104
Issue: 11
Pages: 4518-23
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Publication
18775323 | J:138774
First Author: Li G
Year: 2008
Journal: Mol Cell
Title: Lymphocyte-specific compensation for XLF/cernunnos end-joining functions in V(D)J recombination.
Volume: 31
Issue: 5
Pages: 631-40
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Publication
25075129 | J:214608
First Author: Avagyan S
Year: 2014
Journal: Blood
Title: Hematopoietic stem cell dysfunction underlies the progressive lymphocytopenia in XLF/Cernunnos deficiency.
Volume: 124
Issue: 10
Pages: 1622-5
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Publication
19103754 | J:145721
First Author: Malivert L
Year: 2009
Journal: Mol Cell Biol
Title: The C-terminal domain of Cernunnos/XLF is dispensable for DNA repair in vivo.
Volume: 29
Issue: 5
Pages: 1116-22
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Publication
28051062 | J:238544
 
First Author: Liu X
Year: 2017
Journal: Nat Commun
Title: PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.
Volume: 8
Pages: 13816
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Publication
21160472 | J:167995
First Author: Zha S
Year: 2011
Journal: Nature
Title: ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks.
Volume: 469
Issue: 7329
Pages: 250-4
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Publication
31123184 | J:277567
First Author: Chen BR
Year: 2019
Journal: J Cell Biol
Title: XLF and H2AX function in series to promote replication fork stability.
Volume: 218
Issue: 7
Pages: 2113-2123
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Publication
29077092 | J:274050
First Author: Abramowski V
Year: 2018
Journal: Cell Death Differ
Title: PAXX and Xlf interplay revealed by impaired CNS development and immunodeficiency of double KO mice.
Volume: 25
Issue: 2
Pages: 444-452
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Publication
30923523 | J:294578
 
First Author: Roch B
Year: 2019
Journal: Front Immunol
Title: Cernunnos/Xlf Deficiency Results in Suboptimal V(D)J Recombination and Impaired Lymphoid Development in Mice.
Volume: 10
Pages: 443
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Publication
28057860 | J:240170
First Author: Bhargava R
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Contribution of canonical nonhomologous end joining to chromosomal rearrangements is enhanced by ATM kinase deficiency.
Volume: 114
Issue: 4
Pages: 728-733
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Publication
34519267 | J:316933
   
First Author: Roch B
Year: 2021
Journal: Elife
Title: An XRCC4 mutant mouse, a model for human X4 syndrome, reveals interplays with Xlf, PAXX, and ATM in lymphoid development.
Volume: 10
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Publication
35764636 | J:332737
First Author: Vincendeau E
Year: 2022
Journal: Nat Commun
Title: SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.
Volume: 13
Issue: 1
Pages: 3707
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Publication
23207905 | J:194422
First Author: Vera G
Year: 2013
Journal: Mol Cell Biol
Title: Cernunnos deficiency reduces thymocyte life span and alters the T cell repertoire in mice and humans.
Volume: 33
Issue: 4
Pages: 701-11
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Publication
30017584 | J:265834
First Author: Hung PJ
Year: 2018
Journal: Mol Cell
Title: MRI Is a DNA Damage Response Adaptor during Classical Non-homologous End Joining.
Volume: 71
Issue: 2
Pages: 332-342.e8
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Publication
27798842 | J:236776
First Author: Balmus G
Year: 2016
Journal: Genes Dev
Title: Synthetic lethality between PAXX and XLF in mammalian development.
Volume: 30
Issue: 19
Pages: 2152-2157
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Publication
30356064 | J:267747
First Author: Wang X
Year: 2018
Journal: Nat Commun
Title: SOX17 regulates uterine epithelial-stromal cross-talk acting via a distal enhancer upstream of Ihh.
Volume: 9
Issue: 1
Pages: 4421
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Publication
26833222 | J:236288
 
First Author: Lescale C
Year: 2016
Journal: Nat Commun
Title: RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair.
Volume: 7
Pages: 10529
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Publication
30579708 | J:286916
 
First Author: Castañeda-Zegarra S
Year: 2019
Journal: DNA Repair (Amst)
Title: Synthetic lethality between DNA repair factors Xlf and Paxx is rescued by inactivation of Trp53.
Volume: 73
Pages: 164-169
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Publication
28759779 | J:277029
 
First Author: Xing M
Year: 2017
Journal: DNA Repair (Amst)
Title: Synthetic lethality between murine DNA repair factors XLF and DNA-PKcs is rescued by inactivation of Ku70.
Volume: 57
Pages: 133-138
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Publication
23345432 | J:194333
First Author: Oksenych V
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joining.
Volume: 110
Issue: 6
Pages: 2234-9
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Publication
33289702 | J:305955
First Author: Castañeda-Zegarra S
Year: 2020
Journal: Aging (Albany NY)
Title: Leaky severe combined immunodeficiency in mice lacking non-homologous end joining factors XLF and MRI.
Volume: 12
Issue: 23
Pages: 23578-23597
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Publication
21459848 | J:182963
First Author: Laulier C
Year: 2011
Journal: Nucleic Acids Res
Title: The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation.
Volume: 39
Issue: 14
Pages: 5935-44
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Publication
23969417 | J:210718
First Author: Kakarougkas A
Year: 2013
Journal: Nucleic Acids Res
Title: Opposing roles for 53BP1 during homologous recombination.
Volume: 41
Issue: 21
Pages: 9719-31
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Publication
28846100 | J:260073
First Author: Will AJ
Year: 2017
Journal: Nat Genet
Title: Composition and dosage of a multipartite enhancer cluster control developmental expression of Ihh (Indian hedgehog).
Volume: 49
Issue: 10
Pages: 1539-1545
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
10512203 | J:93290
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
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Publication
15840001 | J:110088
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Nhej1<em1Smoc> | MGI:7291308
Name: non-homologous end joining factor 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
27855634 | J:239407
First Author: Rubin A
Year: 2016
Journal: BMC Genomics
Title: Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq.
Volume: 17
Issue: 1
Pages: 936
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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